Pulmonary Function Testing (PFT) for Obstructive Sleep Apnea (OSA)

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Emory University Hospital Midtown, Atlanta, GA
Obstructive Sleep Apnea (OSA)+2 More
Pulmonary Function Testing (PFT) - Device
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This trial will study if lung volume has an effect on sleep apnea severity by observing patients during a drug induced sleep endoscopy. Pulmonary Function Testing (PFT) is a treatment for Obstructive Sleep Apnea (OSA) that has been approved by the FDA for a different condition. No patients in this trial will receive a placebo.

Eligible Conditions

  • Obstructive Sleep Apnea (OSA)

Treatment Effectiveness

Effectiveness Progress

1 of 3

Other trials for Obstructive Sleep Apnea (OSA)

Study Objectives

6 Primary · 0 Secondary · Reporting Duration: During PFT

During PFT
Expiratory Reserve Volume (ERV)
Functional Residual Capacity (FRC)
During clinical DISE and intervention DISE
Change in Critical Closing Pressure (Pcrit)
Change in Pharyngeal Opening Pressures
Change in VOTE Collapse Patterns - Configuration of Obstruction
Change in VOTE Collapse Patterns - Degree of Obstruction

Trial Safety

Safety Progress

1 of 3

Other trials for Obstructive Sleep Apnea (OSA)

Trial Design

1 Treatment Group

Negative Pressure Ventilator
1 of 1
Experimental Treatment

50 Total Participants · 1 Treatment Group

Primary Treatment: Pulmonary Function Testing (PFT) · No Placebo Group · N/A

Negative Pressure VentilatorExperimental Group · 2 Interventions: Negative Pressure Ventilator, Pulmonary Function Testing (PFT) · Intervention Types: Device, Device
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Pulmonary Function Testing (PFT)
2013
N/A
~10

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: during pft
Closest Location: Emory University Hospital Midtown · Atlanta, GA
Photo of Atlanta 1Photo of Atlanta 2Photo of Atlanta 3
2014First Recorded Clinical Trial
1 TrialsResearching Obstructive Sleep Apnea (OSA)
119 CompletedClinical Trials

Who is running the clinical trial?

Emory UniversityLead Sponsor
1,498 Previous Clinical Trials
2,666,277 Total Patients Enrolled
3 Trials studying Obstructive Sleep Apnea (OSA)
178 Patients Enrolled for Obstructive Sleep Apnea (OSA)
Jason Yu, MDPrincipal InvestigatorEmory University

Eligibility Criteria

Age 18+ · All Participants · 6 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You are an adult patient (≥ 18 yrs) willing and capable of providing informed consent.
You have obstructive sleep apnea.\n
You must be willing and able to provide informed consent to participate in the study.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.

References