Chemet

Arsenic Poisoning, lead, Lead Poisoning + 1 more

Treatment

1 FDA approval

1 Active Study for Chemet

What is Chemet

Succimer

The Generic name of this drug

Treatment Summary

Dimercaprol is a medication used to treat poisoning from heavy metals, by binding to the metals to remove them from the body.

Chemet

is the brand name

image of different drug pills on a surface

Chemet Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Chemet

Succimer

1991

3

Approved as Treatment by the FDA

Succimer, also known as Chemet, is approved by the FDA for 1 uses which include lead .

lead

Effectiveness

How Chemet Affects Patients

Succimer is an oral medication that helps the body get rid of lead. It binds to the lead in the body and makes it easier for it to be passed through urine. Succimer should not be taken as a preventative measure for lead poisoning, and the source of lead exposure should always be identified and removed.

How Chemet works in the body

Succimer binds to heavy metals, like lead, mercury, cadmium, and arsenic, in your blood. It then forms a water-soluble complex that can be easily removed from the body through the kidneys.

When to interrupt dosage

The quantity of Chemet is conditional upon the perceived state, such as Arsenic Poisoning, Poisoning, Lead and lead. The amount of dosage fluctuates as per the mode of delivery (e.g. Capsule - Oral or Injection, powder, lyophilized, for solution) presented in the table beneath.

Condition

Dosage

Administration

lead

, 100.0 mg

Capsule, Oral, Capsule - Oral,

Lead Poisoning

, 100.0 mg

Capsule, Oral, Capsule - Oral,

Mercury Poisoning

, 100.0 mg

Capsule, Oral, Capsule - Oral,

Arsenic Poisoning

, 100.0 mg

Capsule, Oral, Capsule - Oral,

Warnings

There are 1 known major drug interactions with Chemet.

Common Chemet Drug Interactions

Drug Name

Risk Level

Description

Technetium Tc-99m oxidronate

Major

Succimer may decrease effectiveness of Technetium Tc-99m oxidronate as a diagnostic agent.

Chemet Toxicity & Overdose Risk

The toxic dose of succimer in mice has been found to be over 5011 mg/kg. High doses in rats and mice have caused loss of balance, seizures, difficulty breathing, and sometimes death. There have been no reports of human overdosing on succimer, but limited data suggests it can be removed from the blood through dialysis.

image of a doctor in a lab doing drug, clinical research

Chemet Novel Uses: Which Conditions Have a Clinical Trial Featuring Chemet?

No active studies are in progress to examine the effectiveness of Chemet in alleviating Poisoning, Lead, Mercury Poisoning and Lead-Induced Conditions.

Condition

Clinical Trials

Trial Phases

lead

0 Actively Recruiting

Mercury Poisoning

0 Actively Recruiting

Lead Poisoning

0 Actively Recruiting

Arsenic Poisoning

1 Actively Recruiting

Not Applicable

Chemet Reviews: What are patients saying about Chemet?

4.3

Patient Review

5/26/2013

Chemet for Lead Poisoning

My one year old daughter had a lead poisoning level of 39. I kept her on the bottle longer because she couldn't smell it and would drink it. I believe it took two years for her levels to come down, but thankfully they did eventually with this treatment.

3.3

Patient Review

4/7/2009

Chemet for Lead Poisoning

Our daughter has been taking this medication for a while now and we've seen her lead level drop from 52 to 36. We're hoping with time and God's grace, that she'll make a full recovery.

1

Patient Review

5/20/2010

Chemet for Lead Poisoning

I took this medication for four days as prescribed, and I actually feel worse now. I'm constantly nauseous and just generally feeling crummy.

1

Patient Review

6/30/2008

Chemet for Lead Poisoning

I felt extremely ill after taking just one 100 mg tablet of this medication. I had been prescribed as part of a cleansing program.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about chemet

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How do you take succimer?

"The standard dose for succimer is 10mg/kg of body weight, given every 8 hours for 5 days. This dose may be adjusted based on the weight of the child."

Answered by AI

What is chemet used for?

"This medication is used to treat lead poisoning by binding to the lead and removing it from the body through the kidneys to lower the chance of severe problems caused by lead poisoning."

Answered by AI

How does succimer work?

"Succimer helps to remove lead from the body by combining with it in the blood stream and then being removed by the kidneys. This process lessens the damage that lead can cause to organs and tissues."

Answered by AI

How long do DMSA side effects last?

"The majority of cases involving adverse symptoms resolved within a week of discontinuing treatment. In one instance, a child being treated with DMSA appeared to lose some skills permanently, according to the child's parents."

Answered by AI

Clinical Trials for Chemet