What is Chemet
SuccimerThe Generic name of this drug
Treatment SummaryDimercaprol is a medication used to treat poisoning from heavy metals, by binding to the metals to remove them from the body.
Chemetis the brand name
Chemet Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Chemet
Succimer
1991
3
Approved as Treatment by the FDA
Succimer, also known as Chemet, is approved by the FDA for 1 uses which include lead .lead
Effectiveness
How Chemet Affects PatientsSuccimer is an oral medication that helps the body get rid of lead. It binds to the lead in the body and makes it easier for it to be passed through urine. Succimer should not be taken as a preventative measure for lead poisoning, and the source of lead exposure should always be identified and removed.
How Chemet works in the bodySuccimer binds to heavy metals, like lead, mercury, cadmium, and arsenic, in your blood. It then forms a water-soluble complex that can be easily removed from the body through the kidneys.
When to interrupt dosage
The quantity of Chemet is conditional upon the perceived state, such as Arsenic Poisoning, Poisoning, Lead and lead. The amount of dosage fluctuates as per the mode of delivery (e.g. Capsule - Oral or Injection, powder, lyophilized, for solution) presented in the table beneath.Condition
Dosage
Administration
Poisoning, Lead
100.0 mg, , 1.0 mg
Capsule - Oral, Injection, powder, lyophilized, for solution, Intravenous, Capsule, Oral, , Injection, powder, lyophilized, for solution - Intravenous
lead
100.0 mg, , 1.0 mg
Capsule - Oral, Injection, powder, lyophilized, for solution, Intravenous, Capsule, Oral, , Injection, powder, lyophilized, for solution - Intravenous
Arsenic Poisoning
100.0 mg, , 1.0 mg
Capsule - Oral, Injection, powder, lyophilized, for solution, Intravenous, Capsule, Oral, , Injection, powder, lyophilized, for solution - Intravenous
Mercury Poisoning
100.0 mg, , 1.0 mg
Capsule - Oral, Injection, powder, lyophilized, for solution, Intravenous, Capsule, Oral, , Injection, powder, lyophilized, for solution - Intravenous
Warnings
There are 1 known major drug interactions with Chemet.Common Chemet Drug Interactions
Drug Name
Risk Level
Description
Technetium Tc-99m oxidronate
Major
Succimer may decrease effectiveness of Technetium Tc-99m oxidronate as a diagnostic agent.
Chemet Toxicity & Overdose RiskThe toxic dose of succimer in mice has been found to be over 5011 mg/kg. High doses in rats and mice have caused loss of balance, seizures, difficulty breathing, and sometimes death. There have been no reports of human overdosing on succimer, but limited data suggests it can be removed from the blood through dialysis.
Chemet Novel Uses: Which Conditions Have a Clinical Trial Featuring Chemet?
No active studies are in progress to examine the effectiveness of Chemet in alleviating Poisoning, Lead, Mercury Poisoning and Lead-Induced Conditions.Condition
Clinical Trials
Trial Phases
Poisoning, Lead
0 Actively Recruiting
Mercury Poisoning
0 Actively Recruiting
lead
0 Actively Recruiting
Arsenic Poisoning
0 Actively Recruiting
Chemet Reviews: What are patients saying about Chemet?
4.3Patient Review
5/26/2013 My one year old daughter had a lead poisoning level of 39. I kept her on the bottle longer because she couldn't smell it and would drink it. I believe it took two years for her levels to come down, but thankfully they did eventually with this treatment.
3.3Patient Review
4/7/2009 Our daughter has been taking this medication for a while now and we've seen her lead level drop from 52 to 36. We're hoping with time and God's grace, that she'll make a full recovery.
1Patient Review
5/20/2010 I took this medication for four days as prescribed, and I actually feel worse now. I'm constantly nauseous and just generally feeling crummy.
1Patient Review
6/30/2008 I felt extremely ill after taking just one 100 mg tablet of this medication. I had been prescribed as part of a cleansing program.
Patient Q&A Section about chemet
How do you take succimer?
"The standard dose for succimer is 10mg/kg of body weight, given every 8 hours for 5 days. This dose may be adjusted based on the weight of the child." - Anonymous Online Contributor
Unverified Answer
What is chemet used for?
"This medication is used to treat lead poisoning by binding to the lead and removing it from the body through the kidneys to lower the chance of severe problems caused by lead poisoning." - Anonymous Online Contributor
Unverified Answer
How does succimer work?
"Succimer helps to remove lead from the body by combining with it in the blood stream and then being removed by the kidneys. This process lessens the damage that lead can cause to organs and tissues." - Anonymous Online Contributor
Unverified Answer
How long do DMSA side effects last?
"The majority of cases involving adverse symptoms resolved within a week of discontinuing treatment. In one instance, a child being treated with DMSA appeared to lose some skills permanently, according to the child's parents." - Anonymous Online Contributor
Unverified Answer