Capex

Otitis Externa, Uveitis, Perianal erythema + 30 more
Treatment
2 FDA approvals
20 Active Studies for Capex

What is Capex

Fluocinolone acetonideThe Generic name of this drug
Treatment SummaryFluocinolone acetonide is a steroid used in skin medications and implantable devices. It helps reduce inflammation and has been studied for its use in medical implants. In 2016, the FDA approved a device containing fluocinolone acetonide developed by Taro Pharmaceuticals.
Neo-Synalaris the brand name
image of different drug pills on a surface
Capex Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Neo-Synalar
Fluocinolone acetonide
1963
93

Approved as Treatment by the FDA

Fluocinolone acetonide, otherwise called Neo-Synalar, is approved by the FDA for 2 uses like Uveitis and Uveitis .
Uveitis
Uveitis

Effectiveness

How Capex Affects PatientsFluocinolone acetonide is a medication that works by reducing inflammation and narrowing blood vessels. It is given as an implant in the eye to treat uveitis, a condition that causes inflammation. Studies have found that it can reduce the recurrence of uveitis flares by two times compared to patients who did not take it, and it can also cause a slight increase in eye pressure. It is important to monitor eye pressure while taking fluocinolone acetonide.
How Capex works in the bodyFluocinolone acetonide is a corticosteroid that reduces inflammation by preventing the release of certain molecules that cause swelling and irritation. It does this by binding to the glucocorticoid receptor, which then helps to create proteins that block the release of arachidonic acid - the precursor of inflammatory molecules like prostaglandins and leukotrienes.

When to interrupt dosage

The proposed dose of Capex is contingent upon the recognized illness, including Hemorrhoids, Perianal erythema and Itch. The quantity of dosage is contingent upon the technique of application (e.g. Kit or Emulsion - Topical) outlined in the table beneath.
Condition
Dosage
Administration
Uveitis
, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg
Topical, , Cream, Cream - Topical, Solution, Solution - Topical, Ointment, Ointment - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Intravitreal, Implant - Intravitreal, Implant, Shampoo - Topical, Shampoo, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Gel, Emulsion, Emulsion - Topical, Intraocular, Implant - Intraocular
Dermatosis
, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg
Topical, , Cream, Cream - Topical, Solution, Solution - Topical, Ointment, Ointment - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Intravitreal, Implant - Intravitreal, Implant, Shampoo - Topical, Shampoo, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Gel, Emulsion, Emulsion - Topical, Intraocular, Implant - Intraocular
Uveitis
, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg
Topical, , Cream, Cream - Topical, Solution, Solution - Topical, Ointment, Ointment - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Intravitreal, Implant - Intravitreal, Implant, Shampoo - Topical, Shampoo, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Gel, Emulsion, Emulsion - Topical, Intraocular, Implant - Intraocular
Psoriasis of the scalp
, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg
Topical, , Cream, Cream - Topical, Solution, Solution - Topical, Ointment, Ointment - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Intravitreal, Implant - Intravitreal, Implant, Shampoo - Topical, Shampoo, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Gel, Emulsion, Emulsion - Topical, Intraocular, Implant - Intraocular
Skin
, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg
Topical, , Cream, Cream - Topical, Solution, Solution - Topical, Ointment, Ointment - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Intravitreal, Implant - Intravitreal, Implant, Shampoo - Topical, Shampoo, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Gel, Emulsion, Emulsion - Topical, Intraocular, Implant - Intraocular
Anal disorder
, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg
Topical, , Cream, Cream - Topical, Solution, Solution - Topical, Ointment, Ointment - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Intravitreal, Implant - Intravitreal, Implant, Shampoo - Topical, Shampoo, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Gel, Emulsion, Emulsion - Topical, Intraocular, Implant - Intraocular
Perianal erythema
, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg
Topical, , Cream, Cream - Topical, Solution, Solution - Topical, Ointment, Ointment - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Intravitreal, Implant - Intravitreal, Implant, Shampoo - Topical, Shampoo, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Gel, Emulsion, Emulsion - Topical, Intraocular, Implant - Intraocular
Blisters
, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg
Topical, , Cream, Cream - Topical, Solution, Solution - Topical, Ointment, Ointment - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Intravitreal, Implant - Intravitreal, Implant, Shampoo - Topical, Shampoo, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Gel, Emulsion, Emulsion - Topical, Intraocular, Implant - Intraocular
Eczema
, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg
Topical, , Cream, Cream - Topical, Solution, Solution - Topical, Ointment, Ointment - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Intravitreal, Implant - Intravitreal, Implant, Shampoo - Topical, Shampoo, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Gel, Emulsion, Emulsion - Topical, Intraocular, Implant - Intraocular
Skin Inflammation caused by Bacterial Infections
, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg
Topical, , Cream, Cream - Topical, Solution, Solution - Topical, Ointment, Ointment - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Intravitreal, Implant - Intravitreal, Implant, Shampoo - Topical, Shampoo, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Gel, Emulsion, Emulsion - Topical, Intraocular, Implant - Intraocular
Fissure;Anal
, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg
Topical, , Cream, Cream - Topical, Solution, Solution - Topical, Ointment, Ointment - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Intravitreal, Implant - Intravitreal, Implant, Shampoo - Topical, Shampoo, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Gel, Emulsion, Emulsion - Topical, Intraocular, Implant - Intraocular
Eczema
, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg
Topical, , Cream, Cream - Topical, Solution, Solution - Topical, Ointment, Ointment - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Intravitreal, Implant - Intravitreal, Implant, Shampoo - Topical, Shampoo, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Gel, Emulsion, Emulsion - Topical, Intraocular, Implant - Intraocular
Purulent Wounds
, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg
Topical, , Cream, Cream - Topical, Solution, Solution - Topical, Ointment, Ointment - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Intravitreal, Implant - Intravitreal, Implant, Shampoo - Topical, Shampoo, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Gel, Emulsion, Emulsion - Topical, Intraocular, Implant - Intraocular
Secondary Infection
, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg
Topical, , Cream, Cream - Topical, Solution, Solution - Topical, Ointment, Ointment - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Intravitreal, Implant - Intravitreal, Implant, Shampoo - Topical, Shampoo, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Gel, Emulsion, Emulsion - Topical, Intraocular, Implant - Intraocular
Otitis Media
, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg
Topical, , Cream, Cream - Topical, Solution, Solution - Topical, Ointment, Ointment - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Intravitreal, Implant - Intravitreal, Implant, Shampoo - Topical, Shampoo, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Gel, Emulsion, Emulsion - Topical, Intraocular, Implant - Intraocular
Uveitis
, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg
Topical, , Cream, Cream - Topical, Solution, Solution - Topical, Ointment, Ointment - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Intravitreal, Implant - Intravitreal, Implant, Shampoo - Topical, Shampoo, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Gel, Emulsion, Emulsion - Topical, Intraocular, Implant - Intraocular
Surgery; Ear
, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg
Topical, , Cream, Cream - Topical, Solution, Solution - Topical, Ointment, Ointment - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Intravitreal, Implant - Intravitreal, Implant, Shampoo - Topical, Shampoo, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Gel, Emulsion, Emulsion - Topical, Intraocular, Implant - Intraocular
Chronic disease
, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg
Topical, , Cream, Cream - Topical, Solution, Solution - Topical, Ointment, Ointment - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Intravitreal, Implant - Intravitreal, Implant, Shampoo - Topical, Shampoo, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Gel, Emulsion, Emulsion - Topical, Intraocular, Implant - Intraocular
Ear structure
, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg
Topical, , Cream, Cream - Topical, Solution, Solution - Topical, Ointment, Ointment - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Intravitreal, Implant - Intravitreal, Implant, Shampoo - Topical, Shampoo, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Gel, Emulsion, Emulsion - Topical, Intraocular, Implant - Intraocular
Anger Management Therapy
, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg
Topical, , Cream, Cream - Topical, Solution, Solution - Topical, Ointment, Ointment - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Intravitreal, Implant - Intravitreal, Implant, Shampoo - Topical, Shampoo, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Gel, Emulsion, Emulsion - Topical, Intraocular, Implant - Intraocular

Warnings

Capex Contraindications
Condition
Risk Level
Notes
Mycoses
Do Not Combine
External auditory canal structure
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Fluocinolone Acetonide may interact with conjunctiva
Severe Hypersensitivity Reactions
Do Not Combine
Fluocinolone Acetonide may interact with conjunctiva
There are 20 known major drug interactions with Capex.
Common Capex Drug Interactions
Drug Name
Risk Level
Description
2-Methoxyethanol
Major
The risk or severity of adverse effects can be increased when Fluocinolone acetonide is combined with 2-Methoxyethanol.
9-(N-methyl-L-isoleucine)-cyclosporin A
Major
The risk or severity of adverse effects can be increased when Fluocinolone acetonide is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Abatacept
Major
The risk or severity of adverse effects can be increased when Fluocinolone acetonide is combined with Abatacept.
Abemaciclib
Major
The metabolism of Abemaciclib can be increased when combined with Fluocinolone acetonide.
Abetimus
Major
The risk or severity of adverse effects can be increased when Fluocinolone acetonide is combined with Abetimus.
Capex Toxicity & Overdose RiskStudies have not been done to see if fluocinolone acetonide has potential to cause cancer or fertility problems. However, other forms of corticosteroids have been linked to genetic damage, and the Ames test and mouse lymphoma TK assay have shown that this does not apply to fluocinolone acetonide.
image of a doctor in a lab doing drug, clinical research

Capex Novel Uses: Which Conditions Have a Clinical Trial Featuring Capex?

97 active trials are currently assessing the potential of Capex to mitigate Atopic Dermatitis, Otitis Media and Otitis Externa.
Condition
Clinical Trials
Trial Phases
Perianal erythema
0 Actively Recruiting
Friction and Pressure Injuries
0 Actively Recruiting
Chronic disease
0 Actively Recruiting
Itching
11 Actively Recruiting
Phase 2, Phase 4, Phase 3, Phase 1
Wound Infections
0 Actively Recruiting
Surgery; Ear
0 Actively Recruiting
Seborrheic dermatitis of the scalp
0 Actively Recruiting
Uveitis
0 Actively Recruiting
Hemorrhoids
0 Actively Recruiting
postoperative treatment
0 Actively Recruiting
Ear structure
0 Actively Recruiting
Eczema
0 Actively Recruiting
Blisters
0 Actively Recruiting
Skin Inflammation caused by Bacterial Infections
0 Actively Recruiting
Otitis Externa
0 Actively Recruiting
Postoperative Care
1 Actively Recruiting
Not Applicable
Otitis Media
0 Actively Recruiting
Dermatosis
0 Actively Recruiting
Hemorrhoids
0 Actively Recruiting
Acute Otitis Media (AOM)
2 Actively Recruiting
Not Applicable

Patient Q&A Section about capex

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How do you calculate CapEx?

"In order to calculate capital expenditures, you will need the financial statements from your company from the past two years. To get this number, take the fixed assets and subtract the accumulated depreciation. Then, add the total depreciation."

Answered by AI

Is CapEx an asset?

"A capital expenditure is recorded as an asset on a company's balance sheet and is then charged to expense over the useful life of the asset using depreciation."

Answered by AI

What is CapEx and OpEx?

"OpEx, on the other hand, are the expenses incurred from normal business operations, such as labor, rent, and utilities.

A company's capital expenditures are its major, long-term expenses for things like physical assets, while operating expenses are the day-to-day expenses incurred from normal business operations."

Answered by AI

What is an example of CapEx?

"Examples of capital expenditure (CapEx) items might include a new printing press or a fleet of servers for a data center. These items are significant expenses that will provide value for many years to come and can therefore be capitalized over an extended period. Other examples of CapEx include capital leases."

Answered by AI

Clinical Trials for Capex

Have you considered Capex clinical trials? We made a collection of clinical trials featuring Capex, we think they might fit your search criteria.
Have you considered Capex clinical trials? We made a collection of clinical trials featuring Capex, we think they might fit your search criteria.
Have you considered Capex clinical trials? We made a collection of clinical trials featuring Capex, we think they might fit your search criteria.