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What is Armodafinil
ArmodafinilThe Generic name of this drug
Treatment SummaryArmodafinil is a drug used to treat excessive daytime sleepiness in adults caused by obstructive sleep apnea, narcolepsy, or shift work disorder. It is the single-enantiomer form of modafinil (Provigil) and has been proven to improve driving performance in patients with shift work disorder. Armodafinil is produced by Cephalon Inc., a subsidiary of Teva Pharmaceutical Industries Ltd., and was approved by the FDA in 2007.
Nuvigilis the brand name
Armodafinil Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Nuvigil
Armodafinil
2009
66
Approved as Treatment by the FDA
Armodafinil, commonly known as Nuvigil, is approved by the FDA for 5 uses which include Somnolence and Shift-work related sleep disturbance .Somnolence
Helps manage Somnolence
Shift-work related sleep disturbance
Helps manage Shift-work related sleep disturbance
Narcolepsy
Helps manage Narcolepsy
Sleep Disorders, Circadian Rhythm
Helps manage Shift-work related sleep disturbance
Sleepiness
Helps manage Somnolence
Effectiveness
How Armodafinil works in the bodyNuvigil (armodafinil) is a long-lasting stimulant, but how it works is still unknown. It doesn't seem to affect the receptors and enzymes that control sleep and wakefulness. But it does bind to and block the dopamine transporter, stopping dopamine from being reabsorbed. This helps to keep you alert and awake.
When to interrupt dosage
The advised amount of Armodafinil is subject to the diagnosed affliction, such as Narcolepsy, Shift-work related sleep disturbance and Somnolence. The magnitude of dosage fluctuates as per the technique of administration cataloged in the table below.Condition
Dosage
Administration
Sleepiness
, 250.0 mg, 50.0 mg, 100.0 mg, 200.0 mg, 150.0 mg
, Oral, Tablet, Tablet - Oral
Narcolepsy
, 250.0 mg, 50.0 mg, 100.0 mg, 200.0 mg, 150.0 mg
, Oral, Tablet, Tablet - Oral
Sleep Disorders, Circadian Rhythm
, 250.0 mg, 50.0 mg, 100.0 mg, 200.0 mg, 150.0 mg
, Oral, Tablet, Tablet - Oral
Warnings
There are 20 known major drug interactions with Armodafinil.Common Armodafinil Drug Interactions
Drug Name
Risk Level
Description
Anagrelide
Major
The metabolism of Anagrelide can be increased when combined with Armodafinil.
Bendamustine
Major
The metabolism of Bendamustine can be increased when combined with Armodafinil.
Cabozantinib
Major
The metabolism of Cabozantinib can be decreased when combined with Armodafinil.
Capecitabine
Major
The metabolism of Capecitabine can be decreased when combined with Armodafinil.
Capmatinib
Major
The serum concentration of Capmatinib can be decreased when it is combined with Armodafinil.
Armodafinil Novel Uses: Which Conditions Have a Clinical Trial Featuring Armodafinil?
Thirteen active trials are currently investigating the potential of Armodafinil to counter Shift-work related sleep disturbances, Somnolence and Narcolepsy.Condition
Clinical Trials
Trial Phases
Sleep Disorders, Circadian Rhythm
6 Actively Recruiting
Not Applicable, Phase 2, Phase 3
Narcolepsy
1 Actively Recruiting
Phase 1
Sleepiness
7 Actively Recruiting
Not Applicable, Phase 3
Armodafinil Reviews: What are patients saying about Armodafinil?
5Patient Review
10/11/2009 I have taken this for 3 days and have a terrible headache.
5Patient Review
7/29/2020 Nuvigil was such an improvement from the other medications I tried before it. My insurance company made me try several different things before they would cover this, and I'm so glad they did. It's helped me immensely.
4Patient Review
1/12/2011 I experienced good results with this treatment, but unfortunately had to discontinue use because it was too costly. Even with insurance, the out-of-pocket costs were prohibitive.
4Patient Review
9/4/2013 This drug is effective and long-lasting, similar to Nuvigil or Provigil.
3Patient Review
8/6/2021 While this medication does help a little with narcolepsy-induced daytime sleepiness, it unfortunately doesn't do anything for the brain fog that comes along with the condition. It's like my body is awake but my brain isn't. Additionally, it makes me feel dizzy and disoriented, like I stopped taking an antidepressant suddenly.
Patient Q&A Section about armodafinil
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What does armodafinil do to your body?
"Armodafinil is a wakefulness-promoting agent that works by changing the amounts of certain natural substances in the area of the brain that controls sleep and wakefulness."
Answered by AI
Does armodafinil give you energy?
"Armodafinil and modafinil can help people with SWD, narcolepsy, and OSA to stay awake and feel more alert."
Answered by AI
Is armodafinil similar to Adderall?
"Armodafinil is a Schedule II medication, while Adderall is a Schedule III.
Armodafinil (Nuvigil) is a wakefulness-promoting medication similar to Adderall in that it can improve both wakefulness and alertness. However, Armodafinil works differently in the brain and affects different chemicals than Adderall. Armodafinil is classified as a Schedule II medication, while Adderall is classified as a Schedule III."
Answered by AI
Is armodafinil a narcotic?
"Armodafinil is a non-narcotic drug that is classified as a Schedule IV compound. Many patients who suffer from excessive sleepiness may prefer armodafinil because it has a longer duration of effect. Armodafinil is also known for having good compliance rates among patients (low doses)."
Answered by AI
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