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What is Aptiom
Eslicarbazepine acetateThe Generic name of this drug
Treatment SummaryEslicarbazepine acetate (ESL) is a medication used to treat partial-onset seizures that are not adequately controlled with other treatments. It works by blocking the return of voltage-gated sodium channels to their activated state, thus preventing seizure activity. ESL is sold under the brand names Aptiom, Zebinix, and Exalief and comes in 200, 400, 600, or 800mg tablets that can be taken once daily with or without food. Side effects can include dizziness, drowsiness, nausea, vomiting, diarrhea, headache, difficulty concentrating, slowed thinking and speech, depression, and
Aptiomis the brand name
Aptiom Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Aptiom
Eslicarbazepine acetate
2014
5
Approved as Treatment by the FDA
Eslicarbazepine acetate, otherwise called Aptiom, is approved by the FDA for 1 uses which include Seizures .Seizures
Helps manage Partial-Onset Seizures
Effectiveness
How Aptiom Affects PatientsEslicarbazepine acetate will increase your heart rate and lengthen the time between each heartbeat as the dose increases.
How Aptiom works in the bodyEslicarbazepine acetate helps reduce seizures by blocking sodium and calcium channels in the brain. These channels control nerve firing, and when they are blocked, it prevents the repeated firing of neurons that can cause seizures. Eslicarbazepine prevents these channels from returning to their active state, which helps reduce epileptic activity.
When to interrupt dosage
The advisable dose of Aptiom is contingent on the identified affliction. The quantity of dosage fluctuates, depending on the approach of administration (e.g. Suspension or Tablet - Oral) as listed in the table beneath.Condition
Dosage
Administration
Seizures
, 400.0 mg, 600.0 mg, 800.0 mg, 200.0 mg, 50.0 mg/mL
, Oral, Tablet, Tablet - Oral, Kit - Oral, Kit, Suspension, Suspension - Oral
Warnings
Aptiom ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Eslicarbazepine Acetate may interact with Pulse Frequency
Common Aptiom Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The metabolism of Abemaciclib can be increased when combined with Eslicarbazepine acetate.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be increased when combined with Eslicarbazepine acetate.
Alectinib
Major
The metabolism of Alectinib can be increased when combined with Eslicarbazepine acetate.
Alpelisib
Major
The metabolism of Alpelisib can be increased when combined with Eslicarbazepine acetate.
Aminophylline
Major
The metabolism of Aminophylline can be increased when combined with Eslicarbazepine acetate.
Aptiom Toxicity & Overdose RiskNo studies have been done to examine the effects of eslicarbazepine acetate use in pregnant women. Animal studies have found that taking eslicarbazepine acetate during pregnancy can lead to birth defects, miscarriages, and slowed growth of the fetus. Taking eslicarbazepine acetate can also lead to mild to moderate liver damage, and overdosing can cause symptoms like low sodium levels, dizziness, nausea, vomiting, feeling very relaxed, tingling around the mouth, trouble with balance, double vision, and other symptoms. There is no specific antidote for an overdose of eslicarbazep
Aptiom Novel Uses: Which Conditions Have a Clinical Trial Featuring Aptiom?
Currently, two clinical trials are investigating the potential of Aptiom to provide relief for Seizure symptoms.Condition
Clinical Trials
Trial Phases
Seizures
2 Actively Recruiting
Phase 3
Aptiom Reviews: What are patients saying about Aptiom?
5Patient Review
2/13/2017 I've been having seizures since the mid-1990's, related to a pituitary tumor. I tried Topamax first and found it uncomfortable. Now I'm using a low dose of Keppra and 1200mg of Aptiom, and no seizures for several years. BUT...it is expensive and if you do not have insurance, it will put you in debt.
5Patient Review
1/12/2018 So far, I haven't had any issues with side effects or seizures. This is really good news!
4.3Patient Review
7/7/2015 Aptiom has been a godsend. I've gone from having 3-4 seizures a month to only 3-4 per year. The downside is that I have to take it at night, which can sometimes lead to balance problems. But even that hasn't stopped me from living my life; I went through physical therapy and everything.
3.7Patient Review
10/4/2016 I'm feeling pretty tired and dizzy, plus my vision is blurry. I'm still having seizures unfortunately.
3.3Patient Review
11/22/2017 The side effects are really bad. I was sweating, agitated, and trembling. And the worst part is that it made me think about killing myself and act on impulse. Any drug that has those kinds of side effects shouldn't be allowed on the market.
3.3Patient Review
12/4/2014 I unfortunately have not been feeling well since I started this medication. Headaches, nausea, muscle pains, and sweats have all become regular occurrences.
3Patient Review
1/23/2015 I'm starting to feel nauseated on day four of this 400mg dosage. I puked earlier today. My neurologist wants me to eventually work up to an 800mg night dose, but I'm rethinking that plan after reading the pamphlet that came with the medicine. I do appreciate the 24 hour coverage though.
3Patient Review
5/2/2016 I was doing well on the lower dosage of 400mg, but when I was increased to 800mg as per my doctor's suggestion, I began experiencing some serious side effects like headaches and difficulty thinking clearly. So,I went back down to 400mg and have been feeling better since.
2.7Patient Review
9/21/2015 This medication has made me very tired. I have also experienced dizziness and nausea since the dosage was increased to 800mg.
2.3Patient Review
11/25/2021 After taking my morning dose of Aptiom, I become a different person. I switch from being happy to seeing things like nasty spirits. When it starts levelling down mid afternoon I become more myself. Does not control my partial seizures. And by the way it causes me severe insomnia. It's by far the worse one I have been on.
1.3Patient Review
12/3/2021 I took the pill as directed and within two hours, I was feeling so ill I had to go to bed. It's been 24 hours since I last took one and I'm still experiencing severe side effects.
1Patient Review
2/7/2016 My girlfriend has been taking this medication for a few weeks now, and she's started seeing evil spirits that keep her up at night. Has anyone else had similar experiences? We're really struggling and could use some help.
Patient Q&A Section about aptiom
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is Aptiom medication used for?
"This drug is used to treat focal seizures. It may help to reduce the number of seizures you have."
Answered by AI
What kind of seizures does Aptiom treat?
"Aptiom is a prescription medicine typically used to treat focal seizures associated with epilepsy in adults and children four years of age or older. Aptiom can be administered orally as a tablet once per day, and can be used alone or in combination with other seizure medicines."
Answered by AI
What are the side effects of Aptiom?
"Common side effects for people taking APTIOM include dizziness, sleepiness, nausea, headache, double vision, vomiting, feeling tired, problems with coordination, blurred vision, and shakiness."
Answered by AI
What does Aptiom do to the brain?
"Aptiom is an antiepileptic (anti-seizure) medication that is believed to work by targeting the activity of sodium channels in the brain. This might help calm down signaling from nerves and brain activity, which can help prevent seizures."
Answered by AI