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Chemotherapy + Radiation/Surgery for Stomach Cancer
Study Summary
This trial looks at how well chemotherapy works when given with radiation or surgery to people with esophageal or gastric cancer that has spread to no more than 3 places in the body.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I am at risk for severe side effects due to a specific enzyme deficiency.I have had chemotherapy or radiation for esophageal or gastric cancer, but not for curing it at its primary site.My doctor expects I have more than 6 months to live and I can care for myself.My bone marrow does not work well.I am currently dealing with a serious infection.My cancer in the esophagus or stomach is confirmed as adenocarcinoma.My tumor is MSI-High.I have 3 or fewer spots of cancer spread that can be seen on scans.I have had serious heart issues like uncontrolled chest pain, heart failure, or a heart attack in the last 6 months.I am not pregnant, as confirmed by a bHCG lab test.My cancer stage was determined using EGD and PET/CT scans.I am currently breastfeeding.
- Group 1: Group I (maintenance chemotherapy)
- Group 2: Group II (local therapy)
- All Individual Drugs Already Approved - Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
- Approved for 5 Other Conditions - This treatment demonstrated efficacy for 5 other conditions.
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
What other previous trials have explored the use of Chemotherapy?
"Currently, there are 204 phase 3 trials and 591 active studies in total researching the efficacy of Chemotherapy. Most of these research sites exist in Adelaide, South Australia though there are 24767 laboratories across the world that have conducted clinical investigations into this treatment modality."
Has Chemotherapy been given the green light by the Food and Drug Administration?
"We have given chemotherapy a score of 2 on our risk assessment scale, as there is evidence that the treatment is safe but no proof yet of its effectiveness."
To what diseases and illnesses is Chemotherapy typically administered?
"Superficial basal cell carcinoma is often managed with chemotherapy, and this form of treatment may also be advantageous for individuals dealing with rectal carcinoma, metastatic colorectal carcinoma, or pancreatic endocrine carcinoma."
Am I eligible to be a participant in this clinical experiment?
"This clinical trial seeks to enrol 100 individuals with malignant stomach neoplasms, ranging in ages from 18 to 79. These participants must meet the following criteria: (1) ECOG performance status 0-2 and a life expectancy of at least 6 months; (2) three or fewer metastatic lesions observable on PET/CT scan; (3) pathologic diagnosis of tumor biopsy or FNA confirming adenocarcinoma histology; (4) women of childbearing age need to have pregnancy test conducted prior to enrollment and agree to use adequate contraception for duration of study plus an additional six months after discontinuation of systemic"
Is enrollment still available for this trial?
"Affirmative. Documentation on clinicaltrials.gov confirms that this medical investigation is actively searching for participants, having been posted to the website in February 2018 and adjusted as recently as September 2022. This research needs roughly one hundred volunteers from a single location."
Does this medical trial include individuals over twenty-five years of age as participants?
"Qualified patients for this research require to be between 18 and 79 years of age. Additionally, there are 35 studies available for minors and 1761 trials designed for those aged 65 or older."
How many participants have been selected for this research endeavor?
"Indeed, the information on clinicaltrials.gov reveals that this experiment is currently seeking participants. This study was initially shared on February 19th 2018 and has been revised most recently on September 20th 2022. 100 candidates need to be sourced from 1 medical facility for this trial to progress."
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