Your session is about to expire
← Back to Search
Multidomain Exercise & Cognitive Training for Aging-related Cognitive Decline (ACTIONcR Trial)
N/A
Recruiting
Led By Louis Bherer, PhD
Research Sponsored by Louis Bherer
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Normal or corrected vision and normal hearing for their age range
Adult aged 60 and older
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline and post-intervention at 12 months.
Awards & highlights
ACTIONcR Trial Summary
This trial is designed to investigate the effect of different types of exercise on the neurocognitive functioning of sedentary older adults with and without cardiovascular risk factors.
Who is the study for?
This trial is for sedentary adults aged 60 and older who are generally healthy, with no cognitive impairment (scoring at least 25 on the MMSE), and have normal vision and hearing for their age. It's not suitable for those with severe cardiovascular or respiratory diseases, excessive alcohol consumption, certain heart conditions, uncontrolled mental health issues within the past six months, neurological diseases or dementia.Check my eligibility
What is being tested?
The ACTIONcardioRisk trial examines if a combination of aerobic exercises, resistance training, and brain exercises can help prevent memory loss in older adults who don't exercise much but may have heart health risks. Participants will be guided through specific physical and cognitive activities.See study design
What are the potential side effects?
While this program focuses on safe exercises and brain games designed to improve health without significant risk, some participants might experience muscle soreness or fatigue due to new physical activities. Cognitive training typically does not cause side effects.
ACTIONcR Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
My vision and hearing are normal or corrected to normal for my age.
Select...
I am 60 years old or older.
ACTIONcR Trial Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ baseline and post-intervention at 12 months.
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline and post-intervention at 12 months.
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Change in episodic memory
Change in executive functions
Change in general cognitive functioning
+1 moreSecondary outcome measures
Change in brain structure
Change in cerebral activity
Change in cerebral autoregulation - frontal cortical region
+6 moreOther outcome measures
Baseline level of physical activity
Change in Balance performance
Change in Dietary patterns
+35 moreACTIONcR Trial Design
3Treatment groups
Experimental Treatment
Active Control
Group I: Physical exercise interventionExperimental Treatment1 Intervention
The physical exercises intervention will include aerobic and resistance exercises training, three sessions per week for 46 weeks. Participants will be allowed to perform cognitive and exercise training sessions either home-based or centre-based.
Group II: Multidomain interventionExperimental Treatment2 Interventions
The multidomain intervention will combine a cognitive training with aerobic and resistance exercises training, three sessions per week for 46 weeks. Participants will be allowed to perform cognitive and exercise training sessions either home-based or centre-based.
Group III: Active control interventionActive Control1 Intervention
The active control intervention will include stretching and toning exercises, three sessions per week for 46 weeks. Participants will be allowed to perform cognitive and exercise training sessions either home-based or centre-based.
Find a Location
Who is running the clinical trial?
Louis BhererLead Sponsor
5 Previous Clinical Trials
272 Total Patients Enrolled
3 Trials studying Aging
178 Patients Enrolled for Aging
Canadian Institutes of Health Research (CIHR)OTHER_GOV
1,344 Previous Clinical Trials
26,453,258 Total Patients Enrolled
14 Trials studying Aging
4,433 Patients Enrolled for Aging
The Montreal Health Innovations Coordinating Center (MHICC)OTHER
13 Previous Clinical Trials
10,727 Total Patients Enrolled
1 Trials studying Aging
216 Patients Enrolled for Aging
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- My vision and hearing are normal or corrected to normal for my age.I cannot tolerate heavy physical activity.I am 60 years old or older.I have symptoms from a narrowed heart valve.I have long-term heart failure.I have atrial fibrillation.I have a neurological condition.I have a respiratory condition like asthma or COPD.I have been diagnosed with atherosclerosis in my brain, limbs, or heart.I have dangerous heart rhythms when I exercise.
Research Study Groups:
This trial has the following groups:- Group 1: Multidomain intervention
- Group 2: Physical exercise intervention
- Group 3: Active control intervention
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
How many participants are contributing to this research project?
"Affirmative. Clinicaltrials.gov documents the fact that this research project, which was first listed on September 1st 2021, is still enrolling patients. The total count of participants sought after stands at 318 from a single site."
Answered by AI
What are the desired outcomes of this trial?
"This experiment's primary goal is to gauge changes in executive functions over the course of 12 months. In addition, secondary objectives include measuring Cerebral VasoReactivity (CVR) using TCD and NIRS on middle cerebral arteries and prefrontal cortex respectively as well as Pulsatility with NIRS applied to the prefrontal cortical region."
Answered by AI
Are there any unfilled slots available in this research project?
"Affirmative. As indicated by the clinicaltrials.gov data, this clinical trial is currently accepting participants. This trial was first posted on September 1st 2021 and has most recently been updated on September 29th 2021; 318 individuals need to be recruited from one medical centre."
Answered by AI
Recent research and studies
Other Trials to Consider
Popular Categories
Share this study with friends
Copy Link
Messenger