Alyacen 1/35

Endometriosis, Low Testosterone, Osteoporosis + 16 more
Treatment
20 Active Studies for Alyacen 1/35

What is Alyacen 1/35

NorethisteroneThe Generic name of this drug
Treatment SummaryNorethisterone is a synthetic hormone that mimics the effects of progesterone. It is classified as a second-generation progestin, and is more potent than other progestins like levonorgestrel. It is used to treat irregular menstruation, endometriosis, and as a form of contraception and hormone replacement therapy. It was first developed in 1951 in Mexico City and was not marketed for use as an oral contraceptive until 1962.
Neconis the brand name
image of different drug pills on a surface
Alyacen 1/35 Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Necon
Norethisterone
1967
347

Effectiveness

How Alyacen 1/35 Affects PatientsNorethisterone is a synthetic pill taken to prevent pregnancy or treat hormone-related issues, such as menopause or endometriosis. This medicine works much more powerfully than the hormone progesterone normally found in the body. It works by affecting the pelvic area and preventing ovulation, as well as by stopping the hormones that normally control ovulation. Taking norethisterone can increase the risk of developing breast cancer, so people on this medication should be aware of this risk and regularly check for any suspicious lumps.
How Alyacen 1/35 works in the bodyNorethisterone works by binding to progesterone receptors, which can be found in various parts of the body such as the reproductive tract, breasts, and brain. When used as a contraceptive, it thickens the cervical mucus to make it difficult for sperm to pass through. It also changes the endometrium, making it harder for a fertilized egg to implant there. Finally, it suppresses the release of hormones from the pituitary gland, preventing follicular development and ovulation. When used as a component of hormone replacement therapy in menopausal women, it helps suppress the growth of the endometrium to reduce

When to interrupt dosage

The measure of Alyacen 1/35 is contingent upon the recognized condition, including Atrophic, Fracture and Hormone Replacement Therapy. The dosage likewise fluctuates as per the technique of delivery (e.g. Oral or Tablet) featured in the table beneath.
Condition
Dosage
Administration
Hot flashes
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Hormone Replacement Therapy
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Atrophic
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
female castration
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Low Testosterone
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
hypoestrogenism
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Therapeutic procedure
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Fracture
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Ovarian Failure
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Postmenopausal Osteoporosis
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Vasomotor System
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Oral Contraceptives
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Hormonal Contraception
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Estrogen Deprivation Symptoms
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Menopause
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Endometriosis
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Birth Control
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Osteoporosis
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Endometriosis
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical

Warnings

Alyacen 1/35 has eight contraindications, thus it should not be used when encountering any of the conditions in the below table.Alyacen 1/35 Contraindications
Condition
Risk Level
Notes
active liver disease
Do Not Combine
Thrombophilia
Do Not Combine
Vaginal Hemorrhage
Do Not Combine
Malignant Neoplasms
Do Not Combine
Benign hepatic neoplasm
Do Not Combine
Breast Cancer
Do Not Combine
Thromboembolism
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Norethisterone may interact with Pulse Frequency
There are 20 known major drug interactions with Alyacen 1/35.
Common Alyacen 1/35 Drug Interactions
Drug Name
Risk Level
Description
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Norethisterone.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Norethisterone.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Norethisterone.
Clomipramine
Major
The metabolism of Clomipramine can be increased when combined with Norethisterone.
Copanlisib
Major
The metabolism of Copanlisib can be decreased when combined with Norethisterone.
Alyacen 1/35 Toxicity & Overdose RiskThe lowest toxic dose of oral contraceptives in mice is 6 g/kg and the lowest toxic dose in women is 42 mg/kg. Serious side effects have not been reported from an overdose, but some may experience severe nausea or vomiting.
image of a doctor in a lab doing drug, clinical research

Alyacen 1/35 Novel Uses: Which Conditions Have a Clinical Trial Featuring Alyacen 1/35?

A total of 160 active studies are assessing the potential of Alyacen 1/35 in providing Birth Control, Atrophic Uterine Conditions and Low Testosterone Solutions.
Condition
Clinical Trials
Trial Phases
Estrogen Deprivation Symptoms
0 Actively Recruiting
Hot flashes
22 Actively Recruiting
Phase 2, Not Applicable, Phase 1, Phase 4, Early Phase 1
Osteoporosis
39 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Early Phase 1, Phase 4, Phase 3
Birth Control
31 Actively Recruiting
Not Applicable, Phase 3, Phase 4, Early Phase 1
Endometriosis
30 Actively Recruiting
Phase 3, Not Applicable, Early Phase 1, Phase 2, Phase 4, Phase 1
Low Testosterone
15 Actively Recruiting
Phase 1, Phase 4, Phase 2, Not Applicable
Oral Contraceptives
2 Actively Recruiting
Not Applicable
Hormone Replacement Therapy
0 Actively Recruiting
Therapeutic procedure
0 Actively Recruiting
Menopause
0 Actively Recruiting
Atrophic
5 Actively Recruiting
Phase 2, Phase 4, Not Applicable
Postmenopausal Osteoporosis
3 Actively Recruiting
Not Applicable, Phase 4
Fracture
0 Actively Recruiting
female castration
0 Actively Recruiting
hypoestrogenism
2 Actively Recruiting
Phase 4
Vasomotor System
0 Actively Recruiting
Endometriosis
1 Actively Recruiting
Phase 4
Ovarian Failure
2 Actively Recruiting
Not Applicable, Phase 1
Hormonal Contraception
0 Actively Recruiting

Alyacen 1/35 Reviews: What are patients saying about Alyacen 1/35?

5Patient Review
6/8/2015
Alyacen 1/35 for Birth Control
Alyacen has been great. I was switched after Necon was no longer available and have had the same great results. I've never experienced any of the side affects associated with some birth controls and I have been on it for 6 years.
4.7Patient Review
7/9/2018
Alyacen 1/35 for Abnormally Long or Heavy Periods
I had to switch birth controls because the ones I was taking before made my periods really heavy, but this one regulated them back to normal. The only problem is that it caused me to develop cystic acne, which fortunately cleared up after I started taking minocycline. All in all, it's been an effective medication with few side effects.
4Patient Review
8/19/2016
Alyacen 1/35 for Birth Control
The first week was tough as my body adjusted. I experienced common side effects like dizziness and nausea, but they eventually subsided. There have been some changes in mood, but nothing unmanageable. With extra effort to watch my diet and fluid intake, I haven't seen any change in weight.
4Patient Review
10/20/2017
Alyacen 1/35 for Abnormal Bleeding from the Uterus
I bled quite heavily after taking this medication, to the point where I had to go to the emergency room. Thankfully, it's decreased since then and I'm almost back to normal. However, be sure to take this medication with food in your stomach, preferably at night time.
4Patient Review
2/3/2016
Alyacen 1/35 for Birth Control
I'm on my second pack of this medication and I've had my blood pressure checked twice since starting it. It's been through the roof! Normally, I'm just below 120/80 but yesterday it was 159/98. A week ago, I went to the med stop and it was around the same thing. I've also gained weight and been very moody. The high blood pressure scares me, so I'm going to call my doctor in the morning.
3.7Patient Review
10/26/2018
Alyacen 1/35 for Birth Control
I was on Necon 1/35 for many years, but then I couldn't get it anymore so my doctor switched me to Alyacen 1/35. I haven't been happy with this new pill; it has made me sweat for no reason, emotional, dizzy, and gain 20 pounds! This is totally unlike me and I'm thinking about getting off the pill soon.
2.3Patient Review
2/8/2017
Alyacen 1/35 for Acne
I tried this pill to help with my acne, but it made it worse than it's ever been. I had to switch pills and am now on Yaz.
1Patient Review
6/29/2018
Alyacen 1/35 for Birth Control
I took this for two days and felt awful the entire time. I had constant bees-stinging sensation, my hands and feet felt tingly and painful, and I was nauseous constantly. My va-jj also started hurting for no reason. Do not recommend this birth control at all!
1Patient Review
2/15/2018
Alyacen 1/35 for Abnormally Long or Heavy Periods
I had two heart attacks from clots. The doctors couldn't find any other reason than birth control.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about alyacen 1/35

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Alyacen a good birth control?

"User reviews for Alyacen 1/35 indicate that it is an effective treatment for birth control, with an average rating of 5.1 out of 10 from a total of 27 ratings. 33% of reviewers reported a positive experience, while 44% reported a negative experience."

Answered by AI

Does Alyacen 1/35 cause weight gain?

"While side effects vary from person to person, the most commonly reported ones are headaches, vaginal yeast infections, nausea, menstrual cramps, breast tenderness, abdominal pain, mood changes, bacterial vaginitis, acne, irregular uterine bleeding, and weight gain."

Answered by AI

What type of pill is Alyacen 1 35?

"This medication contains a combination of two hormones, progestin and estrogen, which are used in order to prevent pregnancy. In addition to preventing pregnancy, birth control pills can also make your periods more regular, reduce the amount of blood loss and pain experienced during periods, decrease your risk of developing ovarian cysts, and also treat acne."

Answered by AI

What is Alyacen generic for?

"The FDA has assigned the generic version an "AB" rating, meaning it is equivalent to the brand-name version.

Alyacen 1/35 is a brand name drug. Norethindrone & Eth Estradiol is the generic version of Alyacen 1/35 and has been rated by the FDA as "AB", meaning it is equivalent to the brand-name version."

Answered by AI

Clinical Trials for Alyacen 1/35

Have you considered Alyacen 1/35 clinical trials? We made a collection of clinical trials featuring Alyacen 1/35, we think they might fit your search criteria.
Have you considered Alyacen 1/35 clinical trials? We made a collection of clinical trials featuring Alyacen 1/35, we think they might fit your search criteria.
Have you considered Alyacen 1/35 clinical trials? We made a collection of clinical trials featuring Alyacen 1/35, we think they might fit your search criteria.
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