Adasuve

Schizophrenia, Bipolar Disorder, Acute Agitation
Treatment
20 Active Studies for Adasuve

What is Adasuve

LoxapineThe Generic name of this drug
Treatment SummaryAn antipsychotic medication used to treat schizophrenia.
Loxapineis the brand name
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Adasuve Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Loxapine
Loxapine
1988
78

Effectiveness

How Adasuve Affects PatientsLoxapine is a type of tranquilizer believed to work by blocking dopamine and serotonin receptors in the brain, resulting in a calming effect and reduced aggression. The exact way it works is not yet known.
How Adasuve works in the bodyLoxapine works by blocking dopamine and serotonin receptors in the brain. This reduces the excitability of some areas in the brain, resulting in a calming effect and diminished aggression. The exact mechanism of action is not well understood.

When to interrupt dosage

The prescribed dose of Adasuve is contingent upon the diagnosed condition, such as Acute Agitation, Schizophrenia and Bipolar Disorder. The quantity of dosage is contingent upon the administration technique as indicated in the table below.
Condition
Dosage
Administration
Acute Agitation
, 5.0 mg, 10.0 mg, 50.0 mg, 25.0 mg, 2.5 mg, 13.6 mg, 34.0 mg, 6.8 mg, 68.0 mg, 4.5 mg, 9.1 mg, 50.0 mg/mL, 25.0 mg/mL
, Oral, Capsule, Capsule - Oral, Intramuscular, Liquid, Liquid - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Oral, Liquid - Oral, Respiratory (inhalation), Powder, metered, Powder, metered - Respiratory (inhalation), Aerosol, powder, Aerosol, powder - Respiratory (inhalation)
Schizophrenia
, 5.0 mg, 10.0 mg, 50.0 mg, 25.0 mg, 2.5 mg, 13.6 mg, 34.0 mg, 6.8 mg, 68.0 mg, 4.5 mg, 9.1 mg, 50.0 mg/mL, 25.0 mg/mL
, Oral, Capsule, Capsule - Oral, Intramuscular, Liquid, Liquid - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Oral, Liquid - Oral, Respiratory (inhalation), Powder, metered, Powder, metered - Respiratory (inhalation), Aerosol, powder, Aerosol, powder - Respiratory (inhalation)
Bipolar Disorder
, 5.0 mg, 10.0 mg, 50.0 mg, 25.0 mg, 2.5 mg, 13.6 mg, 34.0 mg, 6.8 mg, 68.0 mg, 4.5 mg, 9.1 mg, 50.0 mg/mL, 25.0 mg/mL
, Oral, Capsule, Capsule - Oral, Intramuscular, Liquid, Liquid - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Oral, Liquid - Oral, Respiratory (inhalation), Powder, metered, Powder, metered - Respiratory (inhalation), Aerosol, powder, Aerosol, powder - Respiratory (inhalation)

Warnings

Adasuve Contraindications
Condition
Risk Level
Notes
Asthma
Do Not Combine
Lung Diseases
Do Not Combine
Brain Injuries, Traumatic
Do Not Combine
Shock
Do Not Combine
Disease
Do Not Combine
Pulmonary Disease, Chronic Obstructive
Do Not Combine
Coma
Do Not Combine
Pulse Frequency
Do Not Combine
Heart Diseases
Do Not Combine
Pheochromocytoma
Do Not Combine
Chronic Obstructive Pulmonary Disease
Do Not Combine
severe, drug-induced depressed states
Do Not Combine
Pulse Frequency
Do Not Combine
Asthma
Do Not Combine
Renal Insufficiency
Do Not Combine
acute respiratory symptoms
Do Not Combine
Anesthesia, Cardiac Procedures
Do Not Combine
severe,drug-induced depressive states
Do Not Combine
Coma
Do Not Combine
Disease
Do Not Combine
Pulse Frequency
Do Not Combine
There are 20 known major drug interactions with Adasuve.
Common Adasuve Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The serum concentration of Abemaciclib can be increased when it is combined with Loxapine.
Aclidinium
Major
The therapeutic efficacy of Aclidinium can be decreased when used in combination with Loxapine.
Amisulpride
Major
Loxapine may increase the antipsychotic activities of Amisulpride.
Arformoterol
Major
The therapeutic efficacy of Arformoterol can be decreased when used in combination with Loxapine.
Axitinib
Major
The serum concentration of Axitinib can be increased when it is combined with Loxapine.
Adasuve Toxicity & Overdose RiskThe lowest toxic dose of this drug in mice when taken orally is 65mg/kg.
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Adasuve Novel Uses: Which Conditions Have a Clinical Trial Featuring Adasuve?

171 active trials are presently being conducted to assess the potential of Adasuve in alleviating Schizophrenia, Bipolar Disorder and Acute Agitation.
Condition
Clinical Trials
Trial Phases
Schizophrenia
108 Actively Recruiting
Phase 3, Not Applicable, Early Phase 1, Phase 4, Phase 2, Phase 1
Acute Agitation
0 Actively Recruiting
Bipolar Disorder
0 Actively Recruiting

Adasuve Reviews: What are patients saying about Adasuve?

4.7Patient Review
2/12/2015
Adasuve for Schizophrenia
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Patient Q&A Section about adasuve

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What class of drug is loxapine?

"Loxapine is a medication used to treat psychosis by decreasing abnormal excitement in the brain."

Answered by AI

What class of drug is Caplyta?

"CAPLYTA belongs to a class of drugs known as atypical antipsychotics."

Answered by AI

How do you use adasuve?

"ADASUVE should only be taken by mouth using the provided inhaler. The recommended dose for acute agitation is 10 mg, given only once within 24 hours."

Answered by AI

Clinical Trials for Adasuve

Have you considered Adasuve clinical trials? We made a collection of clinical trials featuring Adasuve, we think they might fit your search criteria.
Have you considered Adasuve clinical trials? We made a collection of clinical trials featuring Adasuve, we think they might fit your search criteria.
Have you considered Adasuve clinical trials? We made a collection of clinical trials featuring Adasuve, we think they might fit your search criteria.
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