Adalat Cc

Anal sphincter hypertonia, Proctalgia, Altitude Sickness + 12 more
Treatment
3 FDA approvals
20 Active Studies for Adalat Cc

What is Adalat Cc

NifedipineThe Generic name of this drug
Treatment SummaryNifedipine, also known as BAY a 1040, is a type of calcium channel blocker used to treat high blood pressure. This drug was developed by Bayer in 1972 and approved by the FDA in 1981. It is a first generation dihydropyridine drug and since its development, newer versions have been created that have slower onset and longer lasting effects. The most popular version of this drug is called amlodipine.
Procardiais the brand name
image of different drug pills on a surface
Adalat Cc Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Procardia
Nifedipine
1981
355

Approved as Treatment by the FDA

Nifedipine, otherwise called Procardia, is approved by the FDA for 3 uses like Angina, Stable and Failed conventional therapy .
Angina, Stable
Helps manage Chronic Stable Angina Pectoris
Failed conventional therapy
Helps manage Failed conventional therapy
Vasospastic Angina
Helps manage Vasospastic Angina

Effectiveness

How Adalat Cc Affects PatientsNifedipine helps to lower blood pressure and increases the amount of oxygen that the heart receives. To keep these effects going, it should be taken three times per day, typically 10-120mg. Some side effects to be aware of include excessive low blood pressure, chest pain, and heart attack.
How Adalat Cc works in the bodyNifedipine works by blocking calcium from entering cells in your arteries and heart. This reduces the pressure in your vessels and increases the oxygen supply to your heart, helping to relieve angina.

When to interrupt dosage

The recommended dosage of Adalat Cc is based on the diagnosed affliction, such as Achalasia, Ureteral Calculus and Hypertensive disease. The amount deviates according to the delivery approach (e.g. Tablet, film coated, extended release or Capsule) delineated in the table below.
Condition
Dosage
Administration
Vasospastic Angina
30.0 mg, 60.0 mg, 90.0 mg, , 10.0 mg, 20.0 mg, 5.0 mg, 20.0 mg/mL
, Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit; Tablet, delayed release; Tablet, extended release, Kit; Tablet, delayed release; Tablet, extended release - Oral
Failed conventional therapy
30.0 mg, 60.0 mg, 90.0 mg, , 10.0 mg, 20.0 mg, 5.0 mg, 20.0 mg/mL
, Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit; Tablet, delayed release; Tablet, extended release, Kit; Tablet, delayed release; Tablet, extended release - Oral
Ureteral Calculi
30.0 mg, 60.0 mg, 90.0 mg, , 10.0 mg, 20.0 mg, 5.0 mg, 20.0 mg/mL
, Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit; Tablet, delayed release; Tablet, extended release, Kit; Tablet, delayed release; Tablet, extended release - Oral
Proctalgia
30.0 mg, 60.0 mg, 90.0 mg, , 10.0 mg, 20.0 mg, 5.0 mg, 20.0 mg/mL
, Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit; Tablet, delayed release; Tablet, extended release, Kit; Tablet, delayed release; Tablet, extended release - Oral
Angina, Stable
30.0 mg, 60.0 mg, 90.0 mg, , 10.0 mg, 20.0 mg, 5.0 mg, 20.0 mg/mL
, Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit; Tablet, delayed release; Tablet, extended release, Kit; Tablet, delayed release; Tablet, extended release - Oral
Pulmonary Edema
30.0 mg, 60.0 mg, 90.0 mg, , 10.0 mg, 20.0 mg, 5.0 mg, 20.0 mg/mL
, Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit; Tablet, delayed release; Tablet, extended release, Kit; Tablet, delayed release; Tablet, extended release - Oral
Fissure in Ano
30.0 mg, 60.0 mg, 90.0 mg, , 10.0 mg, 20.0 mg, 5.0 mg, 20.0 mg/mL
, Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit; Tablet, delayed release; Tablet, extended release, Kit; Tablet, delayed release; Tablet, extended release - Oral
Altitude Sickness
30.0 mg, 60.0 mg, 90.0 mg, , 10.0 mg, 20.0 mg, 5.0 mg, 20.0 mg/mL
, Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit; Tablet, delayed release; Tablet, extended release, Kit; Tablet, delayed release; Tablet, extended release - Oral
Raynaud Disease
30.0 mg, 60.0 mg, 90.0 mg, , 10.0 mg, 20.0 mg, 5.0 mg, 20.0 mg/mL
, Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit; Tablet, delayed release; Tablet, extended release, Kit; Tablet, delayed release; Tablet, extended release - Oral
Hypertensive disease
30.0 mg, 60.0 mg, 90.0 mg, , 10.0 mg, 20.0 mg, 5.0 mg, 20.0 mg/mL
, Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit; Tablet, delayed release; Tablet, extended release, Kit; Tablet, delayed release; Tablet, extended release - Oral
Hypertensive Emergency
30.0 mg, 60.0 mg, 90.0 mg, , 10.0 mg, 20.0 mg, 5.0 mg, 20.0 mg/mL
, Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit; Tablet, delayed release; Tablet, extended release, Kit; Tablet, delayed release; Tablet, extended release - Oral
Anal sphincter hypertonia
30.0 mg, 60.0 mg, 90.0 mg, , 10.0 mg, 20.0 mg, 5.0 mg, 20.0 mg/mL
, Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit; Tablet, delayed release; Tablet, extended release, Kit; Tablet, delayed release; Tablet, extended release - Oral
Obstetric Labor, Premature
30.0 mg, 60.0 mg, 90.0 mg, , 10.0 mg, 20.0 mg, 5.0 mg, 20.0 mg/mL
, Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit; Tablet, delayed release; Tablet, extended release, Kit; Tablet, delayed release; Tablet, extended release - Oral
Esophageal Achalasia
30.0 mg, 60.0 mg, 90.0 mg, , 10.0 mg, 20.0 mg, 5.0 mg, 20.0 mg/mL
, Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit; Tablet, delayed release; Tablet, extended release, Kit; Tablet, delayed release; Tablet, extended release - Oral
Pulmonary Hypertension
30.0 mg, 60.0 mg, 90.0 mg, , 10.0 mg, 20.0 mg, 5.0 mg, 20.0 mg/mL
, Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit; Tablet, delayed release; Tablet, extended release, Kit; Tablet, delayed release; Tablet, extended release - Oral

Warnings

Adalat Cc has one contraindication, which should be kept in mind when managing any of the conditions mentioned in the table below.Adalat Cc Contraindications
Condition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Nifedipine may interact with Pulse Frequency
There are 20 known major drug interactions with Adalat Cc.
Common Adalat Cc Drug Interactions
Drug Name
Risk Level
Description
Amitriptyline
Major
The metabolism of Amitriptyline can be decreased when combined with Nifedipine.
Amoxapine
Major
The metabolism of Amoxapine can be decreased when combined with Nifedipine.
Anagrelide
Major
The risk or severity of QTc prolongation can be increased when Nifedipine is combined with Anagrelide.
Arsenic trioxide
Major
The risk or severity of QTc prolongation can be increased when Nifedipine is combined with Arsenic trioxide.
Artemether
Major
The risk or severity of QTc prolongation can be increased when Nifedipine is combined with Artemether.
Adalat Cc Toxicity & Overdose RiskThe lowest toxic dose of the drug in rats is 1022mg/kg and in mice is 202mg/kg. Those who overdose may experience low blood pressure, abnormal heart rhythm, and a rapid heartbeat. Treatments for overdose include monitoring vital signs, raising the patient's arms and legs, and administering fluids, vasopressors, and calcium.
image of a doctor in a lab doing drug, clinical research

Adalat Cc Novel Uses: Which Conditions Have a Clinical Trial Featuring Adalat Cc?

101 active clinical trials are currently underway to discern if Adalat Cc can be used to alleviate Achalasia, Hypertensive Emergency and Anal Fissure.
Condition
Clinical Trials
Trial Phases
Pulmonary Edema
0 Actively Recruiting
Hypertensive disease
27 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3
Obstetric Labor, Premature
2 Actively Recruiting
Not Applicable
Angina, Stable
0 Actively Recruiting
Esophageal Achalasia
0 Actively Recruiting
Altitude Sickness
0 Actively Recruiting
Raynaud Disease
1 Actively Recruiting
Phase 4
Pulmonary Hypertension
30 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 1, Early Phase 1
Proctalgia
0 Actively Recruiting
Hypertensive Emergency
1 Actively Recruiting
Phase 4
Fissure in Ano
0 Actively Recruiting
Vasospastic Angina
1 Actively Recruiting
Phase 2, Phase 3
Anal sphincter hypertonia
0 Actively Recruiting
Ureteral Calculi
0 Actively Recruiting
Failed conventional therapy
0 Actively Recruiting

Adalat Cc Reviews: What are patients saying about Adalat Cc?

5Patient Review
5/26/2008
Adalat Cc for High Blood Pressure
This medication has been incredibly helpful for me.
4.7Patient Review
9/17/2009
Adalat Cc for Type of Angina Where Chest Pain Occurs at Rest
This lowered my blood pressure for about five hours after taking it, which is good. However, I would prefer if it were more consistent throughout the day and night.
4.7Patient Review
10/6/2016
Adalat Cc for High Blood Pressure
This drug works well for me in conjunction with Altace. I get the occasional cramping in my lower legs but no other negative side effects that I've noticed.
4.3Patient Review
9/21/2009
Adalat Cc for High Blood Pressure
I've been on this medication for over six years now. I had originally started because of severe chest pains that were frequent and hospitalizing. After some testing, it was determined that I didn't have any blockages, but rather spasms in my arteries. This medication has helped to almost entirely remove the pain and severity when they do occur.
4.3Patient Review
12/4/2007
Adalat Cc for High Blood Pressure
I unfortunately had an allergic reaction to the medication. My baby has also been experiencing diarrhea since I started taking it.
4Patient Review
6/15/2011
Adalat Cc for High Blood Pressure
AdalatXL - 30 mg. was very effective for lowering my blood pressure, to the point where my doctor no longer prescribed it because my readings were too low. However, I began experiencing protein in my urine and chest congestion.
4Patient Review
7/1/2012
Adalat Cc for Type of Angina Where Chest Pain Occurs at Rest
I was on this medication for a little over two years when my angina first developed. At that time, it was classified as "stable." Unfortunately, this past March it progressed to "unstable" angina. I had an angiogram and there's no blockage. The doctors think the spasms are in the muscles around my heart. Once my angina turned unstable, I had to switch to a different medication because this one didn't work anymore.
4Patient Review
10/20/2007
Adalat Cc for High Blood Pressure
3.7Patient Review
10/13/2009
Adalat Cc for High Blood Pressure
I constantly experience muscle cramps and can only sleep for two hours at a time. I also have to use the restroom frequently.
3.7Patient Review
7/11/2009
Adalat Cc for High Blood Pressure
This treatment helped me with my insomnia, but I found that I had to wake up more often to urinate at night.
3.3Patient Review
7/26/2012
Adalat Cc for High Blood Pressure
I've been on this medication for years and have only recently started experiencing negative side effects. These include an itchy rash, hot flashes, swollen legs and ankles. I am seeing my doctor tomorrow to get this sorted out and will be finding a new one afterwards.
3Patient Review
9/28/2010
Adalat Cc for High Blood Pressure
While this medication does effectively control blood pressure, it unfortunately comes with a host of other irritating side effects, such as swelling, flushing, heartburn, and tingling in hands and feet. Additionally, I experienced hair loss while taking this medication. It's frustrating that all hypertension medications seem to come with such a long list of negative side effects.
2.3Patient Review
12/2/2007
Adalat Cc for High Blood Pressure
I'm concerned about the warnings for use of this medication. May cause kidney damage, reduce white cells, destroy cell to cell communication and increase risk to cancer. I just completed treatments for prostrate cancer. Only med that seems to control high blood press.
1.3Patient Review
3/2/2008
Adalat Cc for Occasional Numbness, Prickling, or Tingling of Fingers and Toes
My blood pressure has gone down to 125/85.
1Patient Review
7/7/2008
Adalat Cc for High Blood Pressure
I've been using Adalat CC for eight years now and I'm really happy with it. No negative side effects that I know of, and my blood pressure is great.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about adalat cc

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What does CC stand for in Adalat CC?

"Calcium channel blocking agents are a type of drug that block calcium from entering cells. This can help to reduce blood pressure and treat heart conditions."

Answered by AI

What is the difference between Procardia XL and Adalat CC?

"The main difference between the two drugs is how they release nifedipine. Procardia XL releases nifedipine through an osmotic pump delivery system, while Adalat CC releases it by successively dissolving layers."

Answered by AI

Who makes Adalat CC?

"Aurobindo Pharma's nifedipine extended-release tablets have been approved by the Food and Drug Administration in three dosage strengths. The product, a generic of Alvogen's Adalat CC, is indicated as a treatment for hypertension. Aurobindo's generic will be available in dosage strengths of 30-, 60- and 90mg."

Answered by AI

What are the side effects of Adalat CC?

"anxiety

Perhaps you've been experiencing some side effects from the medication you've been taking. These may include headache, dizziness, fatigue, tiredness, drowsiness, flushing, sleep problems, vivid or abnormal dreams, or anxiety."

Answered by AI

Clinical Trials for Adalat Cc

Image of U Health in Miami, United States.

Cuffless PPG Monitor for High Blood Pressure

18+
All Sexes
Miami, FL
This study aims to validate the accuracy and reliability of blood pressure (BP) estimates obtained over 24 hours using a PPG-based chest-patch device compared to the gold standard ambulatory blood pressure monitoring (ABPM) method using an upper arm cuff-based oscillometric BP device, in both hypertensive and normotensive individuals referred by their provider to undergo a 24-hours ABPM for clinical indication. The Awake/Asleep test, which is the primary test recommended for automated wearable cuffless BP devices that are cuff-calibrated (based on the 2023 European Society of Hypertension (ESH) recommendations for the validation of cuffless blood pressure measuring devices), will be conducted in this study. The secondary aim of the study is to assess the feasibility and convenience of the PPG-based device.
Waitlist Available
Has No Placebo
U Health (+1 Sites)Ziad Zoghby, M.D., M.B.A.Biobeat Technologies Ltd.
Image of UPMC Presybeterian in Pittsburgh, United States.

Telaglenastat for Pulmonary Hypertension

18 - 75
All Sexes
Pittsburgh, PA
The research study is being conducted to evaluate the effectiveness of a drug called Telaglenastat in adults diagnosed with Pulmonary Hypertension (PH). PH is a progressive condition that affects the arteries in the lungs, specifically the pulmonary arteries, which carry blood from the right side of the heart to the lungs. Telaglenastat is not currently approved by the Food and Drug Administration for the treatment of PH. However, the study investigators believe that Telaglenastat may help lower blood pressure in the lungs and improve both heart and lung function. It is important to note that the drug will not be available to participants once the study concludes.
Phase 1 & 2
Waitlist Available
UPMC PresybeterianMichael Risbano, MD
Have you considered Adalat Cc clinical trials? We made a collection of clinical trials featuring Adalat Cc, we think they might fit your search criteria.Go to Trials
Image of University of Alabama at Birmingham in Birmingham, United States.

Dietary Interventions for Hypertension

18+
All Sexes
Birmingham, AL
Natriuretic peptides (NPs) are hormones produced by the heart and play an important role in maintaining cardiovascular health and have favorable metabolic benefits. Low NP levels are associated with an increased likelihood of the development of cardiometabolic diseases like diabetes and hypertension. NP levels are known to be highly heritable, with up to half of the differences in NP levels being explained by genetics. The investigators aim to describe the genetic architecture of NPs by examining the genetic variants associated with NPs, and generate and validate a polygenic score (PGS) for NPs. The investigators will use this NP PGS to examine the association of genetically determined NP levels with cardiometabolic and cardiovascular outcomes. The investigators will conduct a genotype-guided physiological clinical trial that aims to assess the genetic factors affecting NP levels and their impact on blood pressure and NP response to saline infusion, high-salt diet, and low-salt diet. These findings will help support personal medicine approaches to lower the increasing burden of hypertension in the United States.
Waitlist Available
Has No Placebo
University of Alabama at BirminghamPankaj Arora, MD, FAHA
Image of Brigham and Women's Hospital in Boston, United States.

Oral Treprostinil for Raynaud's Disease

18+
All Sexes
Boston, MA
Raynaud's phenomenon is a condition where the blood vessels in participants fingers and toes get too narrow when cold or stressed. This makes participants fingers and toes change colors - they might turn white, then blue, and finally red as blood flow returns. It can be painful and cause numbness or tingling. When participants have Raynaud's, blood vessels react too strongly to cold or stress. Fingers and toes may turn white (blood moves away from the area), blue (lack of oxygen), or red and feel painful or tingly when warming up. These episodes usually last from a few minutes to several hours. There are two types of Raynaud's. Primary Raynaud's (also called Raynaud's disease) itself and isn't connected to other health problems. It's the most common type and affects mostly women under 30. Secondary Raynaud's (also called Raynaud's phenomenon) is caused by other diseases like lupus, scleroderma, or rheumatoid arthritis. This type tends to be more serious and may cause painful sores on fingertips called digital ulcers. For mild cases, staying warm might be enough. But if symptoms are severe, participants doctor might prescribe various medications including calcium channel blockers - blood pressure medicines that help open blood vessels, or other vasodilators - medicines that widen blood vessels. About 40% of people with scleroderma develop painful sores on their fingertips called digital ulcers. These happen when there isn't enough blood flow to heal small injuries. For severe cases with digital ulcers, doctors might use prostacyclin therapy - medicines that mimic a natural substance that opens blood vessels. Oral treprostinil is a newer pill form of prostacyclin therapy that helps improve blood flow. The investigators are conducting a research study testing whether oral treprostinil - a pill that mimics prostacyclin (a natural blood vessel opener) - can help people with severe Raynaud's that doesn't respond to usual treatments. This represents hope for better treatment options for people with the most challenging cases of this condition.
Phase 4
Waitlist Available
Brigham and Women's HospitalAaron B Waxman, MD, PhD
Have you considered Adalat Cc clinical trials? We made a collection of clinical trials featuring Adalat Cc, we think they might fit your search criteria.Go to Trials
Image of University of Oklahoma health sciences Center in Oklahoma City, United States.

Neuromodulation for Pulmonary Arterial Hypertension

18 - 90
All Sexes
Oklahoma City, OK
Patients with Group 1 pulmonary hypertension will be enrolled in this study. Investigators will test the hypothesis of low-level tragal stimulation in patients with pulmonary hypertension. The study will be conducted over 4 weeks and patients will undergo low-level tragus stimulation for 1 hour every day for 4 weeks. At baseline the following tests will be conducted-6-minute walk distance, vascular function testing using noninvasive device and blood samples will be collected. Patient will also undergo a limited echocardiography to assess right ventricular function. After 4 weeks of stimulation patients will come back to undergo these tests again. Investigators hypothesized that low-level tragus stimulation (neuromodulation) will lead to improvement in vascular function, 6-minute walk distance and blood based biomarkers in patients with pulmonary hypertension.
Phase 1 & 2
Waitlist Available
University of Oklahoma health sciences CenterTarun Dasari, MD
Have you considered Adalat Cc clinical trials? We made a collection of clinical trials featuring Adalat Cc, we think they might fit your search criteria.Go to Trials
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