Acuvail

Eye Pain, Inflammation, corneal refractive surgery + 20 more
Treatment
2 FDA approvals
20 Active Studies for Acuvail

What is Acuvail

KetorolacThe Generic name of this drug
Treatment SummaryKetorolac is a type of anti-inflammatory drug used to reduce pain. It is available in pill form, as an injection, nasal spray, and eye drops. It is generally used for post-operative pain, arthritis, menstrual cramps, headaches, muscle and tissue pain, and ankylosing spondylitis. It works similarly to morphine and meperidine, but with fewer side effects.
Toradolis the brand name
image of different drug pills on a surface
Acuvail Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Toradol
Ketorolac
1991
316

Approved as Treatment by the FDA

Ketorolac, also called Toradol, is approved by the FDA for 2 uses like caudal epidural block therapy and induction of Nerve Block .
caudal epidural block therapy
Used to treat caudal epidural block therapy in combination with Bupivacaine
induction of Nerve Block
Used to treat induction of Nerve Block in combination with Bupivacaine

Effectiveness

How Acuvail Affects PatientsKetorolac is a non-selective NSAID that works by blocking the enzymes (COX-1 and COX-2) that convert arachidonic acid to prostaglandins. The COX-1 enzyme is always active and found in blood cells, the stomach lining, and blood vessel walls. The COX-2 enzyme is responsible for inflammation, pain, and fever. Inhibiting the COX-1 enzyme can increase the risk of bleeding and stomach ulcers, whereas targeting the COX-2 enzyme is associated with reducing inflammation and pain. Unfortunately, taking ketorolac
How Acuvail works in the bodyKetorolac is an anti-inflammatory medication that works by blocking the production of prostaglandins. Prostaglandins are chemicals that trigger pain and inflammation. Ketorolac targets an enzyme called cyclooxygenase, which is responsible for producing prostaglandins. By blocking this enzyme, ketorolac is able to reduce pain and inflammation. The "S" enantiomer of ketorolac is the most active form of the drug and is responsible for the majority of its therapeutic effects.

When to interrupt dosage

The suggested dosage of Acuvail is contingent upon the diagnosed circumstances, such as Eye, Macular Edema, Cystoid and Pericarditis Acute. The quantity of dosage can be found in the table beneath, subject to the technique of delivery (e.g. Tablet - Oral or Ophthalmic).
Condition
Dosage
Administration
Eye Pain
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, film coated, Tablet, film coated - Oral, Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Injection, solution, concentrate - Intraocular, Injection, solution, concentrate, Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Epidural; Infiltration; Intramuscular; Intravenous, Kit, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Topical, Spray, metered - Topical, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Miosis disorder
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, film coated, Tablet, film coated - Oral, Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Injection, solution, concentrate - Intraocular, Injection, solution, concentrate, Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Epidural; Infiltration; Intramuscular; Intravenous, Kit, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Topical, Spray, metered - Topical, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Macular Edema, Cystoid
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, film coated, Tablet, film coated - Oral, Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Injection, solution, concentrate - Intraocular, Injection, solution, concentrate, Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Epidural; Infiltration; Intramuscular; Intravenous, Kit, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Topical, Spray, metered - Topical, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Seasonal Allergic Conjunctivitis
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, film coated, Tablet, film coated - Oral, Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Injection, solution, concentrate - Intraocular, Injection, solution, concentrate, Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Epidural; Infiltration; Intramuscular; Intravenous, Kit, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Topical, Spray, metered - Topical, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Cataract Surgery
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, film coated, Tablet, film coated - Oral, Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Injection, solution, concentrate - Intraocular, Injection, solution, concentrate, Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Epidural; Infiltration; Intramuscular; Intravenous, Kit, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Topical, Spray, metered - Topical, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Intraocular Lens Replacement
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, film coated, Tablet, film coated - Oral, Oral, Nasal, Spray, metered, Spray, metered - Nasal, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intramuscular, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Solution - Intramuscular, Injection, solution, concentrate, Intraocular, Injection, solution, concentrate - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous, Liquid - Intramuscular, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Injection, solution - Intraocular, Topical, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Spray, metered - Topical, Kit, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Liquid, Kit - Ophthalmic, Injection - Intramuscular
Macular Edema, Cystoid
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, film coated, Tablet, film coated - Oral, Oral, Nasal, Spray, metered, Spray, metered - Nasal, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intramuscular, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Solution - Intramuscular, Injection, solution, concentrate, Intraocular, Injection, solution, concentrate - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous, Liquid - Intramuscular, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Injection, solution - Intraocular, Topical, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Spray, metered - Topical, Kit, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Liquid, Kit - Ophthalmic, Injection - Intramuscular
Ocular Itching
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, film coated, Tablet, film coated - Oral, Oral, Nasal, Spray, metered, Spray, metered - Nasal, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intramuscular, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Solution - Intramuscular, Injection, solution, concentrate, Intraocular, Injection, solution, concentrate - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous, Liquid - Intramuscular, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Injection, solution - Intraocular, Topical, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Spray, metered - Topical, Kit, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Liquid, Kit - Ophthalmic, Injection - Intramuscular
postoperative ocular pain
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, film coated, Tablet, film coated - Oral, Oral, Nasal, Spray, metered, Spray, metered - Nasal, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intramuscular, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Solution - Intramuscular, Injection, solution, concentrate, Intraocular, Injection, solution, concentrate - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous, Liquid - Intramuscular, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Injection, solution - Intraocular, Topical, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Spray, metered - Topical, Kit, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Liquid, Kit - Ophthalmic, Injection - Intramuscular
Pain
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, film coated, Tablet, film coated - Oral, Oral, Nasal, Spray, metered, Spray, metered - Nasal, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intramuscular, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Solution - Intramuscular, Injection, solution, concentrate, Intraocular, Injection, solution, concentrate - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous, Liquid - Intramuscular, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Injection, solution - Intraocular, Topical, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Spray, metered - Topical, Kit, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Liquid, Kit - Ophthalmic, Injection - Intramuscular
caudal epidural block therapy
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, film coated, Tablet, film coated - Oral, Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Injection, solution, concentrate - Intraocular, Injection, solution, concentrate, Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Epidural; Infiltration; Intramuscular; Intravenous, Kit, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Topical, Spray, metered - Topical, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Macular Edema
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, film coated, Tablet, film coated - Oral, Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Injection, solution, concentrate - Intraocular, Injection, solution, concentrate, Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Epidural; Infiltration; Intramuscular; Intravenous, Kit, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Topical, Spray, metered - Topical, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Acute Coryza
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, film coated, Tablet, film coated - Oral, Oral, Nasal, Spray, metered, Spray, metered - Nasal, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intramuscular, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Solution - Intramuscular, Injection, solution, concentrate, Intraocular, Injection, solution, concentrate - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous, Liquid - Intramuscular, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Injection, solution - Intraocular, Topical, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Spray, metered - Topical, Kit, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Liquid, Kit - Ophthalmic, Injection - Intramuscular
Pupil
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, film coated, Tablet, film coated - Oral, Oral, Nasal, Spray, metered, Spray, metered - Nasal, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intramuscular, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Solution - Intramuscular, Injection, solution, concentrate, Intraocular, Injection, solution, concentrate - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous, Liquid - Intramuscular, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Injection, solution - Intraocular, Topical, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Spray, metered - Topical, Kit, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Liquid, Kit - Ophthalmic, Injection - Intramuscular
induction of Nerve Block
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, film coated, Tablet, film coated - Oral, Oral, Nasal, Spray, metered, Spray, metered - Nasal, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intramuscular, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Solution - Intramuscular, Injection, solution, concentrate, Intraocular, Injection, solution, concentrate - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous, Liquid - Intramuscular, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Injection, solution - Intraocular, Topical, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Spray, metered - Topical, Kit, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Liquid, Kit - Ophthalmic, Injection - Intramuscular
induction of Local Anaesthesia
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, film coated, Tablet, film coated - Oral, Oral, Nasal, Spray, metered, Spray, metered - Nasal, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intramuscular, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Solution - Intramuscular, Injection, solution, concentrate, Intraocular, Injection, solution, concentrate - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous, Liquid - Intramuscular, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Injection, solution - Intraocular, Topical, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Spray, metered - Topical, Kit, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Liquid, Kit - Ophthalmic, Injection - Intramuscular
Pericarditis Acute
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, film coated, Tablet, film coated - Oral, Oral, Nasal, Spray, metered, Spray, metered - Nasal, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intramuscular, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Solution - Intramuscular, Injection, solution, concentrate, Intraocular, Injection, solution, concentrate - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous, Liquid - Intramuscular, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Injection, solution - Intraocular, Topical, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Spray, metered - Topical, Kit, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Liquid, Kit - Ophthalmic, Injection - Intramuscular
Inflammation
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, film coated, Tablet, film coated - Oral, Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Injection, solution, concentrate - Intraocular, Injection, solution, concentrate, Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Epidural; Infiltration; Intramuscular; Intravenous, Kit, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Topical, Spray, metered - Topical, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
corneal refractive surgery
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, film coated, Tablet, film coated - Oral, Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Injection, solution, concentrate - Intraocular, Injection, solution, concentrate, Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Epidural; Infiltration; Intramuscular; Intravenous, Kit, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Topical, Spray, metered - Topical, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Induced Hyperthermia
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, film coated, Tablet, film coated - Oral, Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Injection, solution, concentrate - Intraocular, Injection, solution, concentrate, Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Epidural; Infiltration; Intramuscular; Intravenous, Kit, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Topical, Spray, metered - Topical, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic

Warnings

Acuvail has twenty-eight counterindications. It should not be ingested when encountering any of the illnesses enumerated in the following table.Acuvail Contraindications
Condition
Risk Level
Notes
Heart failure
Do Not Combine
Hyperkalemia
Do Not Combine
Renal Insufficiency
Do Not Combine
Hemorrhagic Disorders
Do Not Combine
Kidney Failure
Do Not Combine
A History of Gastric or Duodenal Ulcers
Do Not Combine
Liver Diseases
Do Not Combine
Major Surgery
Do Not Combine
Pulse Frequency
Do Not Combine
Gastrointestinal Hemorrhage
Do Not Combine
Crohn's Disease
Do Not Combine
suspected cerebrovascular bleeding
Do Not Combine
active Gastrointestinal Bleeding
Do Not Combine
NSAID-Induced Asthma
Do Not Combine
Severe Hepatic Impairment
Do Not Combine
incomplete hemostasis
Do Not Combine
Coronary Artery Bypass Grafting
Do Not Combine
Gastrointestinal Perforation
Do Not Combine
Pulse Frequency
Do Not Combine
Hemorrhage
Do Not Combine
Peptic Ulcer
Do Not Combine
Pulse Frequency
Do Not Combine
Labour
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Third trimester of pregnancy
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Ketorolac may interact with Pulse Frequency
Severe Hypersensitivity Reactions
Do Not Combine
Ketorolac may interact with Pulse Frequency
There are 20 known major drug interactions with Acuvail.
Common Acuvail Drug Interactions
Drug Name
Risk Level
Description
Aceclofenac
Major
The risk or severity of adverse effects can be increased when Ketorolac is combined with Aceclofenac.
Acemetacin
Major
The risk or severity of adverse effects can be increased when Ketorolac is combined with Acemetacin.
Acetylsalicylic acid
Major
The risk or severity of adverse effects can be increased when Ketorolac is combined with Acetylsalicylic acid.
Alclofenac
Major
The risk or severity of adverse effects can be increased when Ketorolac is combined with Alclofenac.
Alminoprofen
Major
The risk or severity of adverse effects can be increased when Ketorolac is combined with Alminoprofen.
Acuvail Toxicity & Overdose RiskTaking higher doses of ketorolac increases your chances of experiencing side effects. Common side effects include abdominal pain, indigestion, nausea, and headaches. Overdosing on ketorolac can cause nausea, vomiting, upper abdominal pain, fatigue, and drowsiness. More severe symptoms such as kidney failure, high blood pressure, and coma are possible but rare. Pregnant women and those trying to conceive should not take ketorolac as it may affect fertility and increase the risk of fetal ductus arteriosus closure. If taken while breastfeeding, the mother should carefully monitor the baby for any adverse effects.
image of a doctor in a lab doing drug, clinical research

Acuvail Novel Uses: Which Conditions Have a Clinical Trial Featuring Acuvail?

188 active trials are currently being conducted to assess the potential of Acuvail in treating Macular Edema, Cystoid, acute, moderate Pain and Intraocular Lens Replacement.
Condition
Clinical Trials
Trial Phases
Inflammation
58 Actively Recruiting
Not Applicable, Early Phase 1, Phase 1, Phase 2, Phase 3, Phase 4
Induced Hyperthermia
0 Actively Recruiting
caudal epidural block therapy
6 Actively Recruiting
Not Applicable, Phase 4, Phase 3, Phase 2
Intraocular Lens Replacement
0 Actively Recruiting
Acute Coryza
0 Actively Recruiting
Macular Edema, Cystoid
0 Actively Recruiting
induction of Nerve Block
0 Actively Recruiting
Pupil
0 Actively Recruiting
Local Anaesthesia therapy
0 Actively Recruiting
corneal refractive surgery
0 Actively Recruiting
Seasonal Allergic Conjunctivitis
0 Actively Recruiting
Eye Pain
0 Actively Recruiting
postoperative ocular pain
0 Actively Recruiting
Eye
0 Actively Recruiting
Ocular Itching
0 Actively Recruiting
Pericarditis Acute
1 Actively Recruiting
Phase 2, Phase 3
Miosis disorder
0 Actively Recruiting
Macular Edema, Cystoid
0 Actively Recruiting
Macular Edema
1 Actively Recruiting
Phase 1, Phase 2
Cataract Surgery
3 Actively Recruiting
Not Applicable, Phase 4

Acuvail Reviews: What are patients saying about Acuvail?

5Patient Review
1/4/2010
Acuvail for Postoperative Pain in Eye
I was prescribed this medication, but unfortunately I haven't been able to use it because my local pharmacies are all out of stock.
4Patient Review
9/10/2010
Acuvail for Postoperative Pain in Eye
My surgery went great! I can't believe how much better my vision is now.
2.7Patient Review
2/12/2010
Acuvail for Postoperative Pain in Eye
After using for a few days, I find that there's a burning sensation in my eye when the drop is applied.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about acuvail

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Acuvail a prescription?

"Acuvail should be used as prescribed by your doctor. Do not use more of it, or use it for a longer time than recommended. Follow the directions on the prescription label. Acuvail is usually given 24 hours before cataract surgery, and continued for up to 14 days after surgery."

Answered by AI

Is Acuvail an NSAID?

"Acuvail is an anti-inflammatory drug that is used to treat post-surgical pain and inflammation or to provide relief from itchy eyes caused by seasonal allergies."

Answered by AI

What does Acuvail cost?

"Acuvail is a medication used to decrease inflammation. It belongs to a class of medications called NSAIDs (nonsteroidal anti-inflammatory drugs). The lowest GoodRx price for the most common version of Acuvail is around $336.48, which is 18% off the average retail price of $413.44."

Answered by AI

What is Acuvail used for?

"This drug is used to relieve eye pain and swelling after cataract surgery. It is classified as an NSAID drug and works by blocking certain natural substances in the body to reduce pain and swelling."

Answered by AI

Clinical Trials for Acuvail

Image of University of California, San Francisco in San Francisco, United States.

Vision Centers for Eye Care

Any Age
All Sexes
San Francisco, CA
The goal of this clinical trial is to evaluate the effect of vision centers on access to eye care and eye health outcomes in South Asia. The main questions it aims to answer are: 1. Do vision centers increase visits to eyecare centers? 2. Do vision centers increase spectacle ownership and wearing? 3. Do vision centers improve visual acuity of the population? Researchers will compare outcomes in communities randomized to have a vision center is established with communities randomized to delay establishment of a vision center. Outcomes will be assessed through population-based surveys at baseline and after two years as well as through hospital records collected throughout the study period.
Waitlist Available
Has No Placebo
University of California, San FranciscoKieran O'Brien, PhD, MPH
Image of UConn Health in Farmington, United States.

Cognitive Remediation for Memory and Thinking Difficulties

18+
All Sexes
Farmington, CT
The goal of this clinical trial is to determine if a neuroscience-based computerized cognitive remediation ("brain training") program can treat neurocognitive dysfunction (i.e., memory or thinking difficulties) that emerges in some older adults following a viral infection. The main questions it aims to answer are: * Does computerized cognitive remediation improve cognitive performance and day-to-day functioning in older adults with postviral neurocognitive dysfunction? * Will treatment effects be maintained over time, leading to better long term cognitive outcomes? * Does the treatment lead to reductions in blood-based markers of inflammation as a potential mechanism of cognitive symptom improvement? * Can the treatment be optimized and refined based on feedback from participants to improve user (patient) experience? Researchers will compare the computerized cognitive remediation program to an active computer-based control condition (alternative computer activities) to see if the computerized cognitive remediation program works to treat postviral neurocognitive dysfunction. Participation takes approximately 43-48 hours over 7 months, with most activities (40-46 hours) completed within the first 7-8 weeks, including: * Initial intake visit: Eligibility confirmation (\~2-3 hours) * Computer activities: About 5 hours per week for \~6 weeks (total \~30 hours) completed on a computer tablet provided by the study and loaned to participants for use during the treatment phase * Weekly remote check-in meetings: \~30 minutes each during treatment * Blood draws: Two sessions (before and after treatment), \~20-30 minutes each * Three research visits: Pre-treatment, post-treatment, and 6-month follow-up (\~2-3 hours each, including assessments of cognitive, emotional, and daily functioning)
Waitlist Available
Has No Placebo
UConn HealthCutter Lindbergh, Ph.D.
Have you considered Acuvail clinical trials? We made a collection of clinical trials featuring Acuvail, we think they might fit your search criteria.Go to Trials
Image of Mount Sinai Hospital in Toronto, Canada.

Intrathecal Morphine for Urinary Retention

18+
All Sexes
Toronto, Canada
Revision total knee arthroplasty (rTKA) is a frequently performed procedure. Adequate pain management is an important feature, especially for fast-track and Enhanced Recovery After Surgery (ERAS) programs. The multimodal approach, including single shot or continuous nerve blocks with catheters and spinal or epidural morphine, is a stablished strategy. Although the administration of intrathecal morphine (IM) has been shown to significantly reduce pain scores, it is not free of adverse effects. Postoperative urinary retention (POUR) is possible and might increase the risk of periprosthetic infection. The purpose of this study is to compare patients undergoing rTKAS under spinal anesthesia with IM to patients undergoing the same procedure, under the same anesthetic technique, but with no IM, for POUR and postoperative pain related outcomes. All patients will have single shot and continuous adductor canal block (CACB) and single shot IPACK (interspace between the popliteal artery and the posterior knee capsule) block. The hypothesis is that postoperative pain control is comparable between the groups, with lower incidence of POUR in patients with no IM given.
Phase 3
Recruiting
Mount Sinai HospitalHermann dos Santos Fernandes, MD, PhD
Image of Abcentra Investigational Site in Los Angeles, United States.

Orticumab for Heart Attack

18+
All Sexes
Los Angeles, CA
The goal of this clinical trial is to determine the clinical effect of orticumab treatment on inflammation in study participants with prior myocardial infarction who have elevated coronary inflammation based on CCTA. The main question it aims to answer is: Clinical effects of orticumab treatment on inflammation of the coronary artery parameters measured with CCTA Researchers will compare the effects with placebo group after 6 months of treatment Participants will Keep the planned study visit appointments Provide complete information about medical and medical history Speak to the study doctor before changing any of non-study treatments, including starting new medications, receiving any vaccinations, or setting out to join any other clinical studies
Phase 2
Recruiting
Abcentra Investigational Site (+6 Sites)Abcentra
Have you considered Acuvail clinical trials? We made a collection of clinical trials featuring Acuvail, we think they might fit your search criteria.Go to Trials
Image of School of Public Health in Bloomington, United States.

High Salt Intake for High Blood Pressure

60 - 85
All Sexes
Bloomington, IN
Most Americans consume excess dietary salt based on the recommendations set by the American Heart Association and Dietary Guidelines for Americans. High dietary salt impairs blood pressure control by affecting systemic blood vessels and the kidneys. These changes contribute to excess salt consumption being associated with increased risk for chronic kidney disease and cardiovascular disease, the leading cause of death in America. Salt is particularly deleterious in older adults who are more likely to exhibit salt-sensitive hypertension. However, salt consumption remains high in the United States. Thus, there is a critical need for strategies to counteract the effects of high dietary salt as consumption is likely not going to decrease. One promising option is ketones, metabolites that are produced in the liver during prolonged exercise and very low-calorie diets. While exercise and low-calorie diets are beneficial, not many people engage in these activities. Limited evidence indicates that ketone supplements improve cardiovascular health in humans. Additionally, published rodent data indicates that ketone supplements prevent high salt-induced increases in blood pressure, blood vessel dysfunction, and kidney injury. Our human pilot data also indicates that high dietary salt reduces intrinsic ketone production, but it is unclear whether ketone supplementation confers humans' protection against high salt similar to rodents. Therefore, the investigators seek to conduct a short-term high-dietary salt study to determine whether ketone supplementation prevents high dietary salt from eliciting increased blood pressure, blood vessel dysfunction, and kidney injury/impaired blood flow. The investigators will also measure inflammatory markers in blood samples and isolate immune cells that control inflammation. Lastly, the investigators will also measure blood ketone concentration and other circulating metabolites that may be altered by high salt, which could facilitate novel therapeutic targets to combat high salt.
Recruiting
Has No Placebo
School of Public Health
Image of Tesla MedBed at Tampa-FL in Tampa, United States.

Biophoton Therapy for Stem Cell Proliferation

18 - 70
All Sexes
Tampa, FL
Study Objective The purpose of this clinical study is to evaluate if biophoton therapy, delivered by Tesla BioHealing® Biophoton Generators (Biophotonizer), can increase self-grown stem cells naturally. Study Design This is a randomized, double-blinded, placebo-controlled intervention clinical study to assess the effectiveness of biophoton therapy in impacting stem cells. Approximately 46 volunteers who want to increase self-grown stem cells will participate in the study. Study Randomization The biostatistician will prepare a randomization schedule including a serial of subject numbers. A subject number will be randomly assigned to each study participant, which will assign them to either the control group or the treatment group. Other than the Informed Consent Form (ICF), all study information will be recorded by using the subject number. The Principal Investigator, study physicians, study nurse, data-entry specialists, and biostatisticians, as well as the participants, will be blinded about who received which product during the first two weeks of study participation.
Recruiting
Online Trial
Tesla MedBed at Tampa-FL (+1 Sites)James Z Liu, MD, PhD
Image of Goldring Center for High Performance Sport in Toronto, Canada.

Physical Activity for Delayed Onset Muscle Soreness

18 - 35
All Sexes
Toronto, Canada
After completing novel activity or exercise we may experience exercise-induced muscle damage (EIMD), resulting in a period of reduced muscle function and delayed onset muscle soreness (DOMS). DOMS is characterized by muscle pain and tenderness that typically resolves within a week. While the precise cause of DOMS is unknown, there is growing evidence implicating damage to the connective tissue that surrounds our muscle fibers and is related to a small amount of inflammation. This inflammation is a normal part of our body's ability to recovery from injuries and may be visualized through the use of ultrasound technology. A variety of recovery techniques have been proposed that may help with the recovery of DOMS such as massage and electrical muscle stimulation, but these are not always accessible. Therefore, we are interested in investigating whether the number of daily steps can affect how you experience DOMS.
Waitlist Available
Has No Placebo
Goldring Center for High Performance Sport
Have you considered Acuvail clinical trials? We made a collection of clinical trials featuring Acuvail, we think they might fit your search criteria.Go to Trials
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Terms of Service·Privacy Policy·Cookies·Security