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Active 1000 mg Tempol Solution for Mucositis

Phase 2
Waitlist Available
Research Sponsored by Matrix Biomed, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 10 weeks
Awards & highlights

Study Summary

This trial will assess whether Tempol can help prevent or reduce toxicities from cisplatin and radiation treatment in head and neck cancer patients. Mucositis, nephrotoxicity, and ototoxicity will be monitored over 10 weeks.

Eligible Conditions
  • Mucositis
  • Ototoxicity
  • Kidney Damage
  • Hearing Loss

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~10 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 10 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Secondary outcome measures
Mucositis
Nephrotoxicity

Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: Active 1000 mg Tempol SolutionActive Control1 Intervention
Patients will take 1000 mg of Tempol a day for the duration of radiation treatment (6-8 weeks)
Group II: Placebo SolutionPlacebo Group1 Intervention
Patients will take placebo solution everyday for the duration of radiation treatment (6-8 weeks)

Find a Location

Who is running the clinical trial?

Matrix Biomed, Inc.Lead Sponsor
5 Previous Clinical Trials
130 Total Patients Enrolled
Benji CraneStudy DirectorMatrix Biomed, Inc.

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Has the FDA cleared Active 1000 mg Tempol Solution for use?

"While Phase 2 trials don't have the same efficacy data as later stages, our team believes that the Active 1000 mg Tempol Solution is safe enough to warrant a score of 2."

Answered by AI

Are there any patients still needed for this experimental treatment?

"According to the latest information available on clinicaltrials.gov, this trial is still recruiting patients. Originally posted on May 13th, 2019; the listing was most recently updated on February 2nd, 2022."

Answered by AI

Has the Active 1000 mg Tempol Solution been studied elsewhere?

"The first study of Active 1000 mg Tempol Solution took place in 2019 at Montefiore Medical Center-Einstein Campus. As of now, there have been 9 completed studies with 4 more clinical trials underway; many of these located in Merced, California."

Answered by AI

How many different sites are coordinating this trial?

"There are 11 total sites for this trial, which are enrolling patients currently. These locations include Mercy Medical Center in Merced, California; University of Washington Medical Center in Seattle, Washington; and Central Coast Medical Oncology in Santa Maria, North carolina."

Answered by AI

Does this clinical trial use any new treatments or drugs?

"Since 2019, Active 1000 mg Tempol Solution has been the subject of medical research. The first clinical trial was sponsored by Matrix Biomed, Inc. and took place in 2019. This initial study involved 120 participants. Following the successful completion of this Phase 1 trial, Active 1000 mg Tempol Solution received approval for Phase 2 trials. As of today, there are 4 active trials underway across 10 cities in 1 country."

Answered by AI
~20 spots leftby Apr 2025