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Moderate-intensity aerobic exercise for Post-Traumatic Stress Disorder

N/A
Recruiting
Research Sponsored by University of Alabama, Tuscaloosa
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Inclusion Criteria for PTSD: 1) male or female sex, 2) right-handed, 3) age 18-64, and 4) a current diagnosis of PTSD where the index event involves interpersonal violence exposure (e.g., physical/sexual assault).
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up collected during fear conditioning, fear extinction, and extinction recall task.
Awards & highlights

Study Summary

This trial will test if doing aerobic exercise after learning to overcome fear can improve memory, physical response, and brain activity related to overcoming fear in people who have experienced trauma, with or without posttraumatic

Who is the study for?
This trial is for right-handed men and women aged 18-64 who have experienced interpersonal violence. It's specifically for those with PTSD, but also includes a control group without PTSD. Participants must not have other conditions that could interfere with the study.Check my eligibility
What is being tested?
The study tests if aerobic exercise after fear extinction learning can help people with PTSD recall how to manage their fear better. Over three days, participants will undergo conditioning, perform exercises, and then be tested on recalling these techniques.See study design
What are the potential side effects?
Since the intervention involves exercise, potential side effects may include typical post-exercise symptoms such as muscle soreness or fatigue. No severe side effects are expected from this type of non-invasive intervention.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am right-handed, aged 18-64, and have PTSD from violence like assault.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~collected during fear conditioning, fear extinction, and extinction recall task.
This trial's timeline: 3 weeks for screening, Varies for treatment, and collected during fear conditioning, fear extinction, and extinction recall task. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Neural activity
Skin conductance responses
Threat expectancy ratings

Trial Design

3Treatment groups
Experimental Treatment
Group I: Moderate-intensity aerobic exerciseExperimental Treatment1 Intervention
Group II: Light-intensity aerobic exerciseExperimental Treatment1 Intervention
Group III: High-intensity aerobic exerciseExperimental Treatment1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Exercise
2016
Completed Phase 1
~760

Find a Location

Who is running the clinical trial?

University of Alabama, TuscaloosaLead Sponsor
44 Previous Clinical Trials
19,396 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Do I meet the necessary criteria to participate in this medical study?

"To be eligible for enrollment in this research study, potential participants must have a diagnosis of post-traumatic stress disorder (PTSD) and fall between the ages of 18 and 64. The clinical trial aims to recruit approximately 120 individuals."

Answered by AI

Are individuals still being accepted for participation in this ongoing medical study?

"Indeed, clinicaltrials.gov indicates that this trial is currently in the recruitment phase. The initial posting of the trial was on January 29th, 2024, and it underwent its most recent update on January 19th, 2024."

Answered by AI

What is the upper limit for patient participation in this particular research endeavor?

"Indeed, the data found on clinicaltrials.gov confirms that this study is presently in the recruitment phase. The trial was initially posted on January 29th, 2024 and underwent its most recent revision on January 19th, 2024. To complete enrollment, a total of 120 participants are sought from a single designated site."

Answered by AI

Is there an age restriction pertaining to patients who are above the age of 45 for participation in this study?

"The study is open to individuals aged 18 and above, but excludes those who are 64 years old or older."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
The Influence of Aerobic Exercise on Consolidation of Fear Extinction Learning in PTSD
Kevin Crombie 2024. "The Influence of Aerobic Exercise on Consolidation of Fear Extinction Learning in PTSD". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06144203.
~80 spots leftby Mar 2029
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