Senyo App for Addiction

Recruiting at 1 trial location

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Mayo Clinic

Disqualifiers: Personality pathology, Severe cognitive impairment, Psychosis, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

70 Participants Needed

Trial Summary

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What data supports the effectiveness of the Senyo App treatment for addiction?

Research shows that mobile apps for addiction treatment, when used alongside standard care, can help reduce substance use. Apps that provide information, monitoring, and motivational tools have been found to enhance the effectiveness of traditional treatments. ^{1 2 3 4 5}

What safety data exists for the Senyo App for Addiction?

There is no specific safety data available for the Senyo App for Addiction, but a systematic review of mobile health applications for addiction found that many apps are designed to inform users about risks and help manage cravings, suggesting a focus on user safety. However, more robust and long-term studies are needed to fully understand their safety and effectiveness. ^{1 6 7 8 9}

How does the Senyo App treatment for addiction differ from other treatments?

The Senyo App treatment for addiction is unique because it leverages mobile health technology to improve access to care and manage cravings, which can help prevent relapse. Unlike traditional treatments, it offers a convenient, smartphone-based approach that can be used alongside standard treatments to enhance effectiveness. ^{1 3 10 11 12}

What is the purpose of this trial?

The purpose of this study is to examine the barriers, facilitators, and optimal processes for implementing a digitally enhanced screening, brief intervention, and referral to treatment (SBIRT) model for Substance Use Disorder SUD treatment among Mayo primary care clinics.

Research Team

Tyler Oesterle

Principal Investigator

Mayo Clinic

Eligibility Criteria

This trial is for individuals with Substance Use Disorder (SUD) who are patients at Mayo primary care clinics. The study aims to understand how a digital tool can help in their treatment.

Inclusion Criteria

Ability to read, write, and understand English

Minimum DAST score of 1+ and audit-C score of 3+

Access and willingness to use a mobile device for asynchronous (text) and synchronous (video) engagement with care

Exclusion Criteria

I choose not to answer questions about thoughts of harming myself.

Diagnosed personality pathology as the primary presenting concern based on clinical judgment, severe cognitive impairment (e.g., intellectual disability or dementia), or psychosis

Inability to actively participate in and learn from psychotherapeutic interaction based on clinical evaluation and clinical judgment

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Waitlist

Subjects randomized to the waitlist group will serve as a control group and receive intervention after 12 weeks on the waitlist

12 weeks

Intervention

Subjects randomized to the Senyo group will begin receiving intervention immediately

12 weeks

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 months

Treatment Details

Interventions

• Senyo App

Trial Overview The trial is testing the 'Senyo App' against a waitlist control group, assessing its effectiveness in enhancing SUD treatment through screening and referrals within primary care settings.

Participant Groups

Group I: Senyo Experimental Treatment 2 Interventions

Subjects randomized to the Senyo group will begin receiving intervention immediately, and will move to the follow-up phase after 12 weeks.

Group II: Waitlist Active Control 2 Interventions

Subjects randomized to the waitlist group will serve as a control group and receive intervention after 12 weeks on the waitlist.

Who Is Running the Clinical Trial?

Mayo Clinic

Lead Sponsor

Trials

3,427

Recruited

3,221,000+

Agency for Healthcare Research and Quality (AHRQ)

Collaborator

Trials

415

Recruited

6,777,000+

Findings from Research

A systematic review of 22 controlled trials found that mobile health applications targeting substance use disorders can effectively reduce substance use, with eight applications showing significant reductions in usage among participants.

Most applications focused on educating users about the risks of substance use and managing cravings, suggesting that addressing cravings is crucial for preventing relapse, although the studies were limited by short durations and variability in their designs.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Inventory and Analysis of Controlled Trials of Mobile Phone Applications Targeting Substance Use Disorders: A Systematic Review. Bahadoor, R., Alexandre, JM., Fournet, L., et al.[2021]

The Internet can significantly enhance addiction treatment by enabling efficient delivery of educational content and secure collection of self-reported data on substance use, making treatment more accessible and effective.

Internet applications support various aspects of addiction treatment, including assessment, monitoring patient outcomes, ongoing recovery support, and training for treatment providers, ultimately improving the quality of care and patient engagement.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

How Internet technology can improve the quality of care for substance use disorders. Cucciare, MA., Weingardt, KR., Humphreys, K.[2019]

Mobile phone applications, when used alongside standard addiction treatments, can enhance the effectiveness of these treatments by providing tools for information, monitoring, motivation, and relapse prevention.

Most studies reviewed indicated that patients using these applications experienced a greater reduction in substance consumption compared to those receiving standard treatment alone.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

[Mobile phone applications for addiction treatment]. Penzenstadler, L., Thorens, G., Bachmann, S.[2022]

The qualitative study involving 20 users of the SURE Recovery app revealed that first impressions, such as trust and personal recommendations, significantly influence the app's uptake among individuals seeking support for substance use issues.

User engagement with the app improved when it provided positive feelings and relevant content, highlighting the importance of incorporating end-user feedback into app design to enhance its effectiveness in addiction recovery.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Lessons for Uptake and Engagement of a Smartphone App (SURE Recovery) for People in Recovery From Alcohol and Other Drug Problems: Interview Study of App Users. Neale, J., Bowen, AM.[2022]

The SIDEAL mobile app was well-accepted by 24 adult patients with alcohol dependence, showing high usage rates (80% of study days) and high satisfaction levels, particularly with its self-register and feedback features.

Participants experienced significant reductions in alcohol consumption over 6 weeks, with binge drinking days decreasing from an average of 25 to 5.8 and mean daily consumption dropping from 6.5 to 1.9 standard units, indicating the app's potential efficacy in managing alcohol dependence.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Self-management and Shared Decision-Making in Alcohol Dependence via a Mobile App: a Pilot Study. Barrio, P., Ortega, L., López, H., et al.[2018]

Out of 651 smartphone apps analyzed for smoking cessation, only 15 were focused specifically on this goal, with a majority categorized as calendars or information tools.

The evaluated apps showed a low adherence to established smoking cessation guidelines, with a mean score of only 12.8, indicating a need for improvement and the development of future apps based on evidence-based practices.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

A review of smartphone apps for smoking cessation available in Portuguese. Formagini, TD., Ervilha, RR., Machado, NM., et al.[2018]

The study aims to evaluate the effectiveness of the 'CureApp Smoking Cessation' (CASC) app in improving smoking cessation rates among individuals with nicotine dependence, alongside a standard 12-week treatment program, with a total of 580 participants expected to be recruited.

CASC is designed to enhance treatment outcomes by providing personalized support through video tutorials, AI advice, and CO monitoring, and the primary outcome will be the continuous abstinence rate from weeks 9-24, which is anticipated to be significantly higher than that of a control app.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

A Novel Smoking Cessation Smartphone App Integrated With a Mobile Carbon Monoxide Checker for Smoking Cessation Treatment: Protocol for a Randomized Controlled Trial. Nomura, A., Tateno, H., Masaki, K., et al.[2020]

References

1. Switzerland pubmed.ncbi.nlm.nih.gov

Inventory and Analysis of Controlled Trials of Mobile Phone Applications Targeting Substance Use Disorders: A Systematic Review. [2021]

2. United Arab Emirates pubmed.ncbi.nlm.nih.gov

How Internet technology can improve the quality of care for substance use disorders. [2019]

3. Switzerland pubmed.ncbi.nlm.nih.gov

[Mobile phone applications for addiction treatment]. [2022]

4. England pubmed.ncbi.nlm.nih.gov

Mobile application recovery support for patients with an alcohol use disorder. Acceptance, usability, and perceived helpfulness. [2022]

5. Canada pubmed.ncbi.nlm.nih.gov

Lessons for Uptake and Engagement of a Smartphone App (SURE Recovery) for People in Recovery From Alcohol and Other Drug Problems: Interview Study of App Users. [2022]

6. England pubmed.ncbi.nlm.nih.gov

Self-management and Shared Decision-Making in Alcohol Dependence via a Mobile App: a Pilot Study. [2018]

7. England pubmed.ncbi.nlm.nih.gov

Augmented reality as a novel approach for addiction treatment: development of a smoking cessation app. [2023]

8. England pubmed.ncbi.nlm.nih.gov

Regulation and accreditation of addictive behaviour applications-navigating the landscape. [2021]

9. England pubmed.ncbi.nlm.nih.gov

Harmful smartphone applications promoting alcohol and illicit substance use: a review and content analysis in the United States. [2021]

10. Brazil pubmed.ncbi.nlm.nih.gov

A review of smartphone apps for smoking cessation available in Portuguese. [2018]

11. Canada pubmed.ncbi.nlm.nih.gov

A Novel Smoking Cessation Smartphone App Integrated With a Mobile Carbon Monoxide Checker for Smoking Cessation Treatment: Protocol for a Randomized Controlled Trial. [2020]

12. England pubmed.ncbi.nlm.nih.gov

Development and evaluation of the See Me Smoke-Free multi-behavioral mHealth app for women smokers. [2022]