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Non-Invasive Cerebral Mapping for Cerebral Autoregulation

N/A

Recruiting

Led By Frederick A Zeiler, MD PhD FRCSC

Research Sponsored by University of Manitoba

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Age > 17

Healthy volunteers (male and female)

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 3 years

Awards & highlights

Study Summary

This trial will use a new wearable and portable imaging system that employs advanced near infrared spectroscopy (NIRS) technology to create maps of the entire brain with high sampling rates. The objectives of the trial are to test and optimize the device, and to explore the impact of aging and sex on regional disparities in cerebral autoregulation (CA).

Who is the study for?

This trial is for healthy volunteers over the age of 17 who want to help test a new brain mapping system. People with a history of cerebrovascular or neurological illness, or systemic vascular issues cannot participate.Check my eligibility

What is being tested?

Researchers are testing a wearable device that uses light (NIRS) and blood pressure monitoring to map how well blood flow in the brain responds to changes like standing up quickly or increased carbon dioxide levels.See study design

What are the potential side effects?

Since this study involves non-invasive techniques and is conducted on healthy individuals, significant side effects are not anticipated. However, some discomfort from wearing the device may occur.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am 18 years old or older.

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I am a healthy volunteer.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 3 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~3 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and 3 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Explore impact of aging and sex on regional disparities in Cerebral Autoregulation

In Vivo testing and optimization of device during various perturbations

Trial Design

1Treatment groups

Experimental Treatment

Group I: Block TestingExperimental Treatment4 Interventions

Perturbations to the system will be investigated through a series of testing (block design separated by baseline rest): A. transient hyperemic response testing via carotid compression methods, B. orthostatic challenge responses (lying-to-sit, sit-to-stand),8 C. vascular chemo-reactivity via fast and slow breathing exercises and D. impact of neurovascular coupling through cognitive/Stroop testing. Work here will establish areas for improvement in real time.

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of ManitobaLead Sponsor

595 Previous Clinical Trials

199,276 Total Patients Enrolled

Health Sciences Centre, Winnipeg, ManitobaOTHER

14 Previous Clinical Trials

8,655 Total Patients Enrolled

Natural Sciences and Engineering Research Council, CanadaOTHER

57 Previous Clinical Trials

2,839 Total Patients Enrolled

Media Library

Block Testing Clinical Trial Eligibility Overview. Trial Name: NCT05433129 — N/A

Cerebral Autoregulation Mapping Research Study Groups: Block Testing

Cerebral Autoregulation Mapping Clinical Trial 2023: Block Testing Highlights & Side Effects. Trial Name: NCT05433129 — N/A

Block Testing 2023 Treatment Timeline for Medical Study. Trial Name: NCT05433129 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there available slots for participants in this experiment?

"Clinicaltrials.gov indicates that this medical trial, which began seeking participants on September 1st 2022 and was last modified June 20th 2022, is not currently enrolling volunteers. Nevertheless, there is one other active study looking for patients at the present moment."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Non-Invasive Mapping of Cerebral Autoregulation Using Near Infrared Spectroscopy

2023. "Non-Invasive Mapping of Cerebral Autoregulation Using Near Infrared Spectroscopy". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05433129.