Povorcitinib for Healthy Subjects
Trial Summary
What is the purpose of this trial?
The purpose of this study is to Assess the Effect of Povorcitinib on Digoxin, Rosuvastatin, and Metformin Pharmacokinetics and the Effect of Probenecid on Povorcitinib Pharmacokinetics When Administered Orally to Healthy Adult Participants.
Research Team
Incyte Medical Monitor
Principal Investigator
Incyte Corporation
Eligibility Criteria
This clinical trial is for healthy adults. Specific eligibility criteria are not provided, but typically participants should have no significant health issues and be on no other medications that could affect the study results.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive oral administration of povorcitinib with digoxin, rosuvastatin, metformin, or probenecid as per cohort assignment
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Povorcitinib
Find a Clinic Near You
Who Is Running the Clinical Trial?
Incyte Corporation
Lead Sponsor
Steven Stein
Incyte Corporation
Chief Medical Officer since 2015
MD from University of Witwatersrand
Hervé Hoppenot
Incyte Corporation
Chief Executive Officer since 2014
MBA from ESSEC Business School