This trial is testing a new, more targeted form of radiation therapy against the standard form of radiation therapy to see if it is just as effective in treating brain metastases.
- Brain Metastases
1 Primary · 7 Secondary · Reporting Duration: 1 year
Awards & Highlights
2 Treatment Groups
20 Gy in 5 Fractions Volumetric Modulated Arc Therapy to Brain Metastases
1 of 2
8 Gy in 1 Fraction Volumetric Modulated Arc Therapy to Brain Metastases
1 of 2
100 Total Participants · 2 Treatment Groups
Primary Treatment: Targeting All Brain Metastases · No Placebo Group · Phase 2
Who is running the clinical trial?
Age 18 - 100 · All Participants · 2 Total Inclusion CriteriaMark “Yes” if the following statements are true for you:
- Mulvenna, Paula, Matthew Nankivell, Rachael Barton, Corinne Faivre-Finn, Paula Wilson, Elaine McColl, Barbara Moore, et al.. 2016. “Dexamethasone and Supportive Care with or Without Whole Brain Radiotherapy in Treating Patients with Non-small Cell Lung Cancer with Brain Metastases Unsuitable for Resection or Stereotactic Radiotherapy (QUARTZ): Results from a Phase 3, Non-inferiority, Randomised Trial”. The Lancet. Elsevier BV. doi:10.1016/s0140-6736(16)30825-x.
- Alan Nichol 2022. "RAPid SimPLE Targeted Radiation Treatment for Brain Metastases". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05050929.
Frequently Asked Questions
What health risks have been identified with Targeting All Brain Metastases?
"Our experts at Power have judged the safety of Targeting All Brain Metastases to be a 2, due to this being a Phase 2 trial. This implies that there is data in support of its security, yet no proof that it actually works as intended." - Anonymous Online Contributor
How many participants can join this examination?
"Affirmative. According to clinicaltrials.gov, this medical experiment is presently enlisting patients who meet the eligibility criteria. It was first advertised on July 1st 2022 and updated as recently as October 1 of the same year; it aims to recruit 100 participants from a single site." - Anonymous Online Contributor
To what demographic is this research opportunity available?
"Patient recruitment for this trial is seeking to enrol 100 individuals, aged 18 or above and below the age of 65, who have been diagnosed with neoplasm metastasis. Additionally, those accepted must possess a DS-GPA ≤ 2.0; brain tumours that can be contoured and targeted; an expected median survival time too short for surgery/stereotactic radiosurgery; a willingness to partake in regular imaging follow up sessions; as well as any size of extracranial disease." - Anonymous Online Contributor
Is the age qualification for this trial less than seventy-five years old?
"According to the study's eligibility requirements, the minimum age for participation is 18 and seniors up to 100 years old are able to join." - Anonymous Online Contributor
Are there any opportunities for volunteers to join this research project?
"Affirmative. The clinical trial's entry on clinicialtrials.gov reveals that the study, which was initially posted on July 1st 2022, is actively recruiting volunteers. There are one hundred participants needed from a single research centre to complete this investigation." - Anonymous Online Contributor