Your session is about to expire
← Back to Search
Immunotherapy for Bladder Cancer
Study Summary
This trial looks at new treatments for people with advanced urothelial cancer who can't take chemotherapy.
Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
Find a Location
Who is running the clinical trial?
Media Library
- I have high calcium levels in my blood that are causing symptoms.I have had lung conditions like pulmonary fibrosis or pneumonitis, or my CT scan shows active pneumonitis.My kidney function is very low.I have had a previous transplant of stem cells or an organ.I haven't taken any experimental drugs recently.I have not taken antibiotics for treatment, only for prevention, in the last 2 weeks.I have or had an autoimmune disease or immune deficiency.I frequently need procedures to remove excess fluid from my chest or abdomen.I am currently on medication for hepatitis B.My blood and organs are functioning well.My heart is healthy and functions well.I have had cancer spread to the lining of my brain and spinal cord.I have not been treated with specific immune therapies like CD137 agonists or anti-TIGIT.I haven't taken any immune-weakening drugs in the last 2 weeks and don't expect to need any during the study.I haven't had a heart or stroke issue in the last 3 months.I haven't had major surgery in the last 4 weeks and don't expect to need one during the study.I have not had a severe infection in the last 4 weeks.I do not have active tuberculosis or a recent Epstein-Barr virus infection.I have not had chemotherapy for my advanced or recurrent bladder cancer.I haven't had a live vaccine recently and don't plan to during or soon after treatment.My cancer is a type of bladder cancer that has spread and includes urothelial cells.I have pain from my cancer that isn't managed well.I have brain metastases that are untreated or getting worse.I have not had cancer other than bladder cancer in the last 2 years, except for very low-risk types.I haven't had cancer treatment, including chemo or hormonal therapy, in the last 3 weeks.I cannot receive platinum-based chemotherapy due to health reasons.I have a leftover tumor sample available for PD-L1 testing.I can perform daily activities with minimal assistance.I haven't taken immune-boosting drugs in the last 4 weeks or 5 half-lives.
- Group 1: Arm B
- Group 2: Arm C
- Group 3: Arm A
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
To what degree do the risks of Arm B outweigh its potential benefits?
"Due to its Phase 2 status, Arm B was assigned a score of two on our safety scale as there is evidence for the drug's security but not yet any data backing up efficacy."
Is this research currently accessible to potential participants?
"Correct. According to the data accessible on clinicaltrials.gov, this medical trial which was initially posted on April 13th 2023 is actively seeking participants. A total of 240 patients are needed from 31 different sites for enrollment in the study."
In which geographic areas is this experiment being conducted?
"Numerous medical centres have recruited patients for this trial, including Advent Health Orlando in Orlando, SCRI Mark H. Zangmeister Center in Columbus and the Tennessee Oncology Chattanooga site in Chattanooga. Altogether 31 sites are actively recruiting participants."
How many participants are actively engaging in the experiment?
"Affirmative. According to the clinicaltrials.gov registry, this scientific trial started accepting applicants on April 13th 2023 and is still actively seeking participants. There are 31 sites across the country participating in this study, which requires 240 patients for completion."
Share this study with friends
Copy Link
Messenger