L-Serine for Lou Gehrig's Disease

Dartmouth-Hitchcock Medical Center, Lebanon, NH
Lou Gehrig's DiseaseL-Serine - Drug
All Sexes
What conditions do you have?

Study Summary

This trial is testing a new ALS treatment to see if it is safe and effective.

Eligible Conditions
  • Lou Gehrig's Disease

Treatment Effectiveness

Phase-Based Effectiveness

1 of 3
Phase 2

Study Objectives

1 Primary · 3 Secondary · Reporting Duration: Baseline, 1 year

6 months
Dose tolerability based on subject reporting
Baseline, 1 year
Efficacy based on ALS Functional Rating Scale - Revised (ALSFRS-R)
Baseline, 6 months
Efficacy based on neurological exam
Efficacy based on pulmonary forced vital capacity

Trial Safety

Phase-Based Safety

2 of 3
This is further along than 68% of similar trials

Awards & Highlights

No Placebo Group
All patients enrolled in this trial will receive the new treatment.

Trial Design

1 Treatment Group

1 of 1

Experimental Treatment

43 Total Participants · 1 Treatment Group

Primary Treatment: L-Serine · No Placebo Group · Phase 2

Experimental Group · 1 Intervention: L-Serine · Intervention Types: Drug

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: baseline, 1 year

Who is running the clinical trial?

Elijah W. StommelLead Sponsor
Brain Chemistry Labs, Institute for EthnomedicineUNKNOWN
1 Previous Clinical Trials
40 Total Patients Enrolled
Elijah W Stommel, MD,PHDPrincipal InvestigatorDartmouth-Htichcock Medical Center

Eligibility Criteria

Age 18+ · All Participants · 3 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:

Frequently Asked Questions

What maladies has L-Serine been found to alleviate?

"L-Serine has proven to be an efficacious therapy when treating iron deficiency and supplementing amino acid deficiencies." - Anonymous Online Contributor

Unverified Answer

Has the FDA sanctioned L-Serine for therapeutic applications?

"Our team at Power has evaluated the safety of L-Serine and assigned it a score of 2 due to evidence from Phase 2 trials that suggest its harmlessness, yet lack any proof for effectiveness." - Anonymous Online Contributor

Unverified Answer

What is the current cohort size of this clinical trial?

"Affirmative. The information on clinicaltrials.gov suggests that enrollment for this trial is ongoing - the study was established on October 24th 2018 and the details were last updated on February 22nd 2022. At present, they are seeking 50 participants from one location." - Anonymous Online Contributor

Unverified Answer

Could you tell me if this clinical experiment is currently seeking participants?

"Affirmative. Data from clinicaltrials.gov shows that this medical trial, which commenced on October 24th 2018, is actively seeking participants for enrolment. 50 patients are needed to be recruited from one location." - Anonymous Online Contributor

Unverified Answer

Has L-Serine been investigated in prior empirical investigations?

"Currently, 4 clinical trials exploring the effects of L-Serine are ongoing with none in their final stages. While Lebanon, New Hampshire has a concentration of these studies, there exists another 5 sites where research is taking place." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.