Fast-Track Surgery for Hip and Knee Replacement

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Maisonneuve-Rosemont Hospital

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 2

150 Participants Needed

Trial Summary

What is the purpose of this trial?

Implementation of Fast-track surgery for total hip replacement and total knee replacement and evaluation of the risks and benefits for the patients.

Will I have to stop taking my current medications?

The trial does not specify if you need to stop taking your current medications, but it excludes those on long-term anticoagulation therapy, systemic corticotherapy, or treatment with certain medications affecting liver enzymes. It's best to discuss your specific medications with the trial team.

What data supports the effectiveness of the treatment Fast-track Total Hip and Knee Arthroplasty?

Fast-track hip and knee replacement surgery helps patients recover faster and spend less time in the hospital. Studies show it leads to quicker recovery, higher patient satisfaction, and fewer complications after surgery. ^{1 2 3 4 5}

Is fast-track surgery for hip and knee replacement safe?

Fast-track surgery for hip and knee replacement has been shown to reduce hospital stay and complications compared to traditional methods, indicating it is generally safe for humans. ^{2 3 5 6 7}

How is fast-track surgery for hip and knee replacement different from other treatments?

Fast-track surgery for hip and knee replacement is unique because it focuses on reducing the time patients spend in the hospital by using minimally invasive techniques and encouraging early mobilization. This approach allows patients to recover more quickly and take responsibility for their own care soon after surgery, often leading to higher satisfaction and faster recovery. ^{1 2 3 5 8}

Eligibility Criteria

This trial is for adults aged 18-75 needing a primary total hip or knee replacement, without severe psychiatric issues, inflammatory joint diseases, obesity (BMI over 40), recent serious blood clots, or special perisurgical care. Participants must live near Maisonneuve-Rosemont Hospital and have support at home post-surgery.

Inclusion Criteria

I need a standard hip or knee replacement without special procedures.

Patient able to give their informed consent

I have someone to support me before, during, and after my surgery for a week.

Exclusion Criteria

Psychiatric disease limiting participation in the study

I have a joint disease like rheumatoid arthritis or lupus.

I am currently taking medication that affects CYP3A4 enzyme activity.

Timeline

Screening

Participants are screened for eligibility to participate in the trial

up to 3 months

1 visit (in-person)

Surgery and Immediate Recovery

Participants undergo total hip or knee replacement surgery and are monitored for immediate recovery outcomes

1 day

1 visit (in-person)

Post-Surgery Monitoring

Participants are monitored for complications, pain management, and recovery progress

1 year

Multiple visits (in-person and virtual)

Follow-up

Participants are monitored for safety and effectiveness after treatment

1 year

Treatment Details

Interventions

• Fast-track Total Hip and knee arthroplasty

Trial Overview The study tests a 'Fast-track' surgery program for patients undergoing total hip or knee replacements. It aims to evaluate how this approach affects recovery times and overall outcomes compared to traditional surgical methods.

Participant Groups

Group I: Fast-track total hip or knee arthroplasty Experimental Treatment 1 Intervention

Be able to return patient home on the same day of a total hip or knee surgery.

Who Is Running the Clinical Trial?

Maisonneuve-Rosemont Hospital

Lead Sponsor

Trials

102

Recruited

38,300+

References

1. England pubmed.ncbi.nlm.nih.gov

Excellent PROM results after fast-track hip and knee arthroplasty with no postoperative restrictions: a cohort study validation of fast-track surgery without postoperative restrictions. [2022]

2. England pubmed.ncbi.nlm.nih.gov

Patients' experiences during the first 12 weeks after discharge in fast-track hip and knee arthroplasty - a qualitative study. [2019]

3. Netherlands pubmed.ncbi.nlm.nih.gov

Fast-track knee arthroplasty -- status and future challenges. [2022]

4. Denmark pubmed.ncbi.nlm.nih.gov

[Fast-track hip arthroplasty]. [2019]

5. Germany pubmed.ncbi.nlm.nih.gov

Reduced length of stay following hip and knee arthroplasty in Denmark 2000-2009: from research to implementation. [2022]

6. Spain pubmed.ncbi.nlm.nih.gov

Fast-track recovery technique applied to primary total hip and knee replacement surgery. Analysis of costs and complications. [2022]

7. Denmark pubmed.ncbi.nlm.nih.gov

Temporal trends in length of stay and readmissions after fast-track hip and knee arthroplasty. [2019]

8. Germany pubmed.ncbi.nlm.nih.gov

[Day-case outpatient endoprosthetics-"Ultra-Fast-Track"]. [2022]