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What is Sulfisoxazole
SulfisoxazoleThe Generic name of this drug
Treatment SummarySulfamethoxazole is a short-term antibiotic that can be used to treat bacterial infections caused by both gram-positive and gram-negative bacteria.
Sulfisoxazole Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Sulfisoxazole
0
Approved as Treatment by the FDA
Sulfisoxazole, otherwise called Sulfisoxazole, is approved by the FDA for 1 uses like Acute Otitis Media (AOM) .Acute Otitis Media (AOM)
Used to treat Acute Otitis Media (AOM) in combination with Erythromycin
Effectiveness
How Sulfisoxazole Affects PatientsSulfisoxazole is an antibiotic that can stop bacteria from multiplying. It works by blocking an essential component of bacteria's metabolism. Most sulfonamides, including sulfisoxazole, can be taken orally, though it can be difficult to administer it in other ways because it is a very alkaline and irritating substance. It is able to spread throughout the body, and particularly high levels are found in fluids in the eye, the pleural cavity, the peritoneum, and the synovial cavity. Although it is not used to treat meningitis anymore, sulfisoxazole still reaches high levels in
How Sulfisoxazole works in the bodySulfisoxazole works by preventing bacteria from making folic acid. It does this by blocking an enzyme that helps the bacteria combine two molecules in order to form folic acid. Without this enzyme, the bacteria can't make folic acid and can't survive.
When to interrupt dosage
The recommended amount of Sulfisoxazole is contingent upon the determined disorder. The quantity of dosage deviates, as per the method of delivery sketched out in the table hereinafter.Condition
Dosage
Administration
Acute Otitis Media (AOM)
600.0 mg/mL, , 500.0 mg
, Oral, Granule, for suspension - Oral, Tablet, Tablet - Oral, Powder, for suspension, Powder, for suspension - Oral
Warnings
Sulfisoxazole ContraindicationsCondition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Common Sulfisoxazole Drug Interactions
Drug Name
Risk Level
Description
Acenocoumarol
Major
The metabolism of Acenocoumarol can be decreased when combined with Sulfisoxazole.
Amiodarone
Major
The risk or severity of QTc prolongation can be increased when Sulfisoxazole is combined with Amiodarone.
Anagrelide
Major
The risk or severity of QTc prolongation can be increased when Sulfisoxazole is combined with Anagrelide.
Arsenic trioxide
Major
The risk or severity of QTc prolongation can be increased when Sulfisoxazole is combined with Arsenic trioxide.
Artemether
Major
The risk or severity of QTc prolongation can be increased when Sulfisoxazole is combined with Artemether.
Sulfisoxazole Toxicity & Overdose RiskThe lowest toxic dose of the drug in mice is 6800mg/kg when taken orally.
Sulfisoxazole Novel Uses: Which Conditions Have a Clinical Trial Featuring Sulfisoxazole?
One active clinical trial is underway to assess the potential of Sulfisoxazole to ameliorate Acute Otitis Media (AOM).Condition
Clinical Trials
Trial Phases
Acute Otitis Media (AOM)
3 Actively Recruiting
Not Applicable
Patient Q&A Section about sulfisoxazole
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is the brand name for sulfisoxazole?
"The active ingredient in sulfisoxazole is also available under the trade names Sulfafurazole and Gantrisin."
Answered by AI
What is sulfisoxazole used for?
"Sulfisoxazole is an antibiotic used to treat or prevent infections caused by bacteria."
Answered by AI
What bacteria does sulfisoxazole treat?
"This medication is used to treat or prevent a variety of bacterial infections. It may also be used for other purposes not listed in this guide."
Answered by AI
What is the mechanism of action of sulfisoxazole?
"Sulfisoxazole is an antibacterial agent$.
Sulfisoxazole works by preventing the enzyme dihydropteroate synthetase from condensing pteridine with para-aminobenzoic acid (PABA). This inhibits bacterial synthesis of dihydrofolic acid."
Answered by AI