Stendra

Impotence
Treatment
2 FDA approvals
18 Active Studies for Stendra

What is Stendra

AvanafilThe Generic name of this drug
Treatment SummaryAvanafil is a drug used to treat erectile dysfunction. It works by preventing the breakdown of a certain enzyme in the body, allowing blood flow to the penis and resulting in the ability to achieve an erection. Avanafil is less likely than other similar drugs to cause vision problems, but it is less selective than tadalafil. The FDA approved Avanafil in 2012 and the EMA approved it in 2013.
Stendrais the brand name
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Stendra Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Stendra
Avanafil
2013
12

Approved as Treatment by the FDA

Avanafil, otherwise called Stendra, is approved by the FDA for 2 uses including Erectile dysfunction and Impotence .
Erectile dysfunction
Helps manage Erectile Dysfunction
Impotence
Helps manage Erectile Dysfunction

Effectiveness

How Stendra Affects PatientsAvanafil is a medication that works by blocking an enzyme (PDE5) in order to improve blood flow. It is more effective at blocking the enzyme than other similar medications, like sildenafil and vardenafil, so it is less likely to cause vision problems or heart side effects. It also takes effect quickly, usually within fifteen minutes of taking it. Avanafil can have dangerous interactions with certain blood pressure medications and alcohol, and should not be taken by those who have had vision problems in the past.
How Stendra works in the bodyAvanafil helps people get erections by blocking an enzyme that breaks down a compound called cyclic guanosine monophosphate (cGMP). When you are sexually aroused, the body releases a molecule called nitric oxide which causes cGMP to build up in the muscles of the penis. This cGMP relaxes the muscles and allows blood to flow into the penis, creating an erection. Avanafil prevents the breakdown of cGMP so that it can remain at higher levels, helping to keep the erection. However, this only works when you are aroused, as avanafil needs nitric

When to interrupt dosage

The recommended dose of Stendra is contingent upon the diagnosed disorder. The quantity of the dosage fluctuates in regard to the method of administration detailed in the table beneath.
Condition
Dosage
Administration
Impotence
50.0 mg, 100.0 mg, 200.0 mg,
, Oral, Tablet, Tablet - Oral

Warnings

Stendra Contraindications
Condition
Risk Level
Notes
Retinal Degeneration
Do Not Combine
Renal Insufficiency
Do Not Combine
Pulse Frequency
Do Not Combine
Heart failure
Do Not Combine
Severe Hepatic Impairment
Do Not Combine
Pulse Frequency
Do Not Combine
Hypotension
Do Not Combine
Pulse Frequency
Do Not Combine
Optic Neuropathy, Ischemic
Do Not Combine
Angina, Unstable
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Avanafil may interact with Pulse Frequency
There are 20 known major drug interactions with Stendra.
Common Stendra Drug Interactions
Drug Name
Risk Level
Description
Alprostadil
Major
The risk or severity of hypotension and priapism can be increased when Avanafil is combined with Alprostadil.
Amyl Nitrite
Major
The risk or severity of hypotension can be increased when Avanafil is combined with Amyl Nitrite.
Doxofylline
Major
The risk or severity of adverse effects can be increased when Avanafil is combined with Doxofylline.
Erythrityl tetranitrate
Major
The risk or severity of hypotension can be increased when Avanafil is combined with Erythrityl tetranitrate.
Fostamatinib
Major
The risk or severity of adverse effects can be increased when Avanafil is combined with Fostamatinib.
Stendra Toxicity & Overdose RiskNot much is known about overdoses of avanafil. Some people have taken single doses of up to 800mg and repeat doses of up to 300mg, and experienced side effects similar to those seen with regular doses, but more intense. Those who overdose on avanafil should receive standard treatments for the symptoms and be supported. Dialysis is not likely to help, as avanafil binds to proteins in the blood.
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Stendra Novel Uses: Which Conditions Have a Clinical Trial Featuring Stendra?

There are 22 active clinical trials assessing the potential of Stendra to combat Impotence.
Condition
Clinical Trials
Trial Phases
Impotence
18 Actively Recruiting
Not Applicable, Phase 4, Early Phase 1, Phase 3, Phase 1

Stendra Reviews: What are patients saying about Stendra?

5Patient Review
1/8/2016
Stendra for Inability to have an Erection
Viagra really helped me out. I was surprised at how quickly it worked and how long the effects lasted.
4.7Patient Review
2/13/2016
Stendra for Inability to have an Erection
100mg is really effective. Just be careful not to drink alcohol while using it, as that will give you a nasty headache.
4Patient Review
3/12/2017
Stendra for Inability to have an Erection
This medication usually works well for me, but my insurance recently stopped covering it. Now I'm trying to figure out what else to ask my doctor for.
3.7Patient Review
9/25/2017
Stendra for Inability to have an Erection
Worked decently quickly, produced rock hard erections. Unfortunately, it also gave me a splitting headache every time I used it.
2.3Patient Review
3/15/2017
Stendra for Inability to have an Erection
I had a surgery to remove cancer which also resulted in erectile dysfunction. Stendra didn't work for me, but Viagra, Cialis or pumps didn't either.
View All Reviews
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Patient Q&A Section about stendra

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the medicine avanafil used for?

"This medicine is used to treat erectile dysfunction in men. It belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors."

Answered by AI

When should I take avanafil?

"Avanafil comes in the form of a tablet that is meant to be taken orally. The recommended dosage for men is 100-mg or 200-mg, and it should be taken with or without food, depending on the need, about 15 minutes before sexual activity. The recommended dosage for men taking the 50-mg dose is to take it with or without food, depending on the need, about 30 minutes before sexual activity."

Answered by AI

Is avanafil good for Ed?

"Avanafil is safe and effective for treating erectile dysfunction in men with diabetes. It is effective as early as 15 minutes and more than 6 hours after dosing. The adverse events seen with avanafil are similar to those seen with other phosphodiesterase 5 inhibitors."

Answered by AI

Can you take avanafil with high blood pressure?

"It is important that your doctor knows when you last took avanafil if you need emergency medical care for a heart problem. Do not use this medicine if you are also using a nitrate medicine, often used to treat angina (chest pain) or high blood pressure."

Answered by AI

Clinical Trials for Stendra

Have you considered Stendra clinical trials? We made a collection of clinical trials featuring Stendra, we think they might fit your search criteria.
Have you considered Stendra clinical trials? We made a collection of clinical trials featuring Stendra, we think they might fit your search criteria.
Have you considered Stendra clinical trials? We made a collection of clinical trials featuring Stendra, we think they might fit your search criteria.
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
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