Sinuva

Dermatophytosis, Asthma, Itching + 14 more

Treatment

2 FDA approvals

20 Active Studies for Sinuva

What is Sinuva

Mometasone furoate

The Generic name of this drug

Treatment Summary

Mometasone furoate is a corticosteroid medication used to treat asthma, allergic rhinitis, and certain skin conditions. It is 22 times more effective than the common corticosteroid dexamethasone, and is available as an inhaler, nasal spray, or ointment.

Elocon

is the brand name

Sinuva Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Elocon

Mometasone furoate

1987

114

Approved as Treatment by the FDA

Mometasone furoate, also known as Elocon, is approved by the FDA for 2 uses including Asthma and Asthma .

Asthma

Helps manage Asthma

Asthma

Helps manage Asthma

Effectiveness

How Sinuva Affects Patients

Mometasone is a synthetic steroid with the ability to target certain pathways in the body that reduce inflammation. It has a much stronger bond to the glucocorticoid receptors than dexamethasone, and a weaker bond to mineralocorticoid receptors, making it more specific in its action. It's able to pass through cell membranes to reach these pathways and help reduce inflammation.

How Sinuva works in the body

Mometasone is used to treat asthma by blocking inflammation-causing molecules like histamine and leukotrienes. It works by entering cells and binding to glucocorticoid receptors, which then move to the nucleus of the cell and dimerize. This causes changes in gene expression that reduce inflammation. Mometasone also blocks certain transcription factors that stimulate inflammation, such as activator-protein-1 and nuclear factor kappa B (NF-kappaB).

When to interrupt dosage

The quantity of Sinuva is contingent upon the determined condition, including Dermatitis, Eczematous caused by surface Fungal skin infection, Psoriasis and Skin Diseases, Eczematous. The dosage fluctuates, in line with the approach of delivery (e.g. Powder or Topical) featured in the table beneath.

Condition

Dosage

Administration

Dermatophytosis

, 0.001 mg/mg, 1.0 mg/mL, 0.05 mg, 0.22 mg, 0.11 mg, 0.1 %, 0.2 mg, 0.1 mg, 1.35 mg, 0.01 mg/mg, 1.0 mg, 0.32 mg, 0.08 mg, 0.16 mg, 0.0625 mg, 0.1275 mg, 0.26 mg, 0.136 mg, 0.1 mg/pump actuation, 0.05 mg/spray, 0.2 mg/pump actuation, 0.05 mg/pump actuation, 0.4 mg/pump actuation, 0.025 mg

Ointment - Topical, Topical, , Lotion, Lotion - Topical, Ointment, Nasal, Spray, metered - Nasal, Spray, metered, Inhalant, Inhalant - Respiratory (inhalation), Respiratory (inhalation), Cream, Solution - Topical, Solution, Cream - Topical, Aerosol, metered - Respiratory (inhalation), Aerosol, metered, Aerosol - Respiratory (inhalation), Aerosol, Intrasinal, Implant - Intrasinal, Implant, Powder, Kit, Kit - Topical, Capsule - Respiratory (inhalation), Capsule, Powder - Respiratory (inhalation), Spray, Spray - Nasal

Asthma

, 0.001 mg/mg, 1.0 mg/mL, 0.05 mg, 0.22 mg, 0.11 mg, 0.1 %, 0.2 mg, 0.1 mg, 1.35 mg, 0.01 mg/mg, 1.0 mg, 0.32 mg, 0.08 mg, 0.16 mg, 0.0625 mg, 0.1275 mg, 0.26 mg, 0.136 mg, 0.1 mg/pump actuation, 0.05 mg/spray, 0.2 mg/pump actuation, 0.05 mg/pump actuation, 0.4 mg/pump actuation, 0.025 mg

Ointment - Topical, Topical, , Lotion, Lotion - Topical, Ointment, Nasal, Spray, metered - Nasal, Spray, metered, Inhalant, Inhalant - Respiratory (inhalation), Respiratory (inhalation), Cream, Solution - Topical, Solution, Cream - Topical, Aerosol, metered - Respiratory (inhalation), Aerosol, metered, Aerosol - Respiratory (inhalation), Aerosol, Intrasinal, Implant - Intrasinal, Implant, Powder, Kit, Kit - Topical, Capsule - Respiratory (inhalation), Capsule, Powder - Respiratory (inhalation), Spray, Spray - Nasal

Itching

, 0.001 mg/mg, 1.0 mg/mL, 0.05 mg, 0.22 mg, 0.11 mg, 0.1 %, 0.2 mg, 0.1 mg, 1.35 mg, 0.01 mg/mg, 1.0 mg, 0.32 mg, 0.08 mg, 0.16 mg, 0.0625 mg, 0.1275 mg, 0.26 mg, 0.136 mg, 0.1 mg/pump actuation, 0.05 mg/spray, 0.2 mg/pump actuation, 0.05 mg/pump actuation, 0.4 mg/pump actuation, 0.025 mg

Ointment - Topical, Topical, , Lotion, Lotion - Topical, Ointment, Nasal, Spray, metered - Nasal, Spray, metered, Inhalant, Inhalant - Respiratory (inhalation), Respiratory (inhalation), Cream, Solution - Topical, Solution, Cream - Topical, Aerosol, metered - Respiratory (inhalation), Aerosol, metered, Aerosol - Respiratory (inhalation), Aerosol, Intrasinal, Implant - Intrasinal, Implant, Powder, Kit, Kit - Topical, Capsule - Respiratory (inhalation), Capsule, Powder - Respiratory (inhalation), Spray, Spray - Nasal

Atopic Dermatitis

, 0.001 mg/mg, 1.0 mg/mL, 0.05 mg, 0.22 mg, 0.11 mg, 0.1 %, 0.2 mg, 0.1 mg, 1.35 mg, 0.01 mg/mg, 1.0 mg, 0.32 mg, 0.08 mg, 0.16 mg, 0.0625 mg, 0.1275 mg, 0.26 mg, 0.136 mg, 0.1 mg/pump actuation, 0.05 mg/spray, 0.2 mg/pump actuation, 0.05 mg/pump actuation, 0.4 mg/pump actuation, 0.025 mg

Ointment - Topical, Topical, , Lotion, Lotion - Topical, Ointment, Nasal, Spray, metered - Nasal, Spray, metered, Inhalant, Inhalant - Respiratory (inhalation), Respiratory (inhalation), Cream, Solution - Topical, Solution, Cream - Topical, Aerosol, metered - Respiratory (inhalation), Aerosol, metered, Aerosol - Respiratory (inhalation), Aerosol, Intrasinal, Implant - Intrasinal, Implant, Powder, Kit, Kit - Topical, Capsule - Respiratory (inhalation), Capsule, Powder - Respiratory (inhalation), Spray, Spray - Nasal

prophylaxis of seasonal Allergic rhinitis

, 0.001 mg/mg, 1.0 mg/mL, 0.05 mg, 0.22 mg, 0.11 mg, 0.1 %, 0.2 mg, 0.1 mg, 1.35 mg, 0.01 mg/mg, 1.0 mg, 0.32 mg, 0.08 mg, 0.16 mg, 0.0625 mg, 0.1275 mg, 0.26 mg, 0.136 mg, 0.1 mg/pump actuation, 0.05 mg/spray, 0.2 mg/pump actuation, 0.05 mg/pump actuation, 0.4 mg/pump actuation, 0.025 mg

Ointment - Topical, Topical, , Lotion, Lotion - Topical, Ointment, Nasal, Spray, metered - Nasal, Spray, metered, Inhalant, Inhalant - Respiratory (inhalation), Respiratory (inhalation), Cream, Solution - Topical, Solution, Cream - Topical, Aerosol, metered - Respiratory (inhalation), Aerosol, metered, Aerosol - Respiratory (inhalation), Aerosol, Intrasinal, Implant - Intrasinal, Implant, Powder, Kit, Kit - Topical, Capsule - Respiratory (inhalation), Capsule, Powder - Respiratory (inhalation), Spray, Spray - Nasal

Hay Fever

, 0.001 mg/mg, 1.0 mg/mL, 0.05 mg, 0.22 mg, 0.11 mg, 0.1 %, 0.2 mg, 0.1 mg, 1.35 mg, 0.01 mg/mg, 1.0 mg, 0.32 mg, 0.08 mg, 0.16 mg, 0.0625 mg, 0.1275 mg, 0.26 mg, 0.136 mg, 0.1 mg/pump actuation, 0.05 mg/spray, 0.2 mg/pump actuation, 0.05 mg/pump actuation, 0.4 mg/pump actuation, 0.025 mg

Ointment - Topical, Topical, , Lotion, Lotion - Topical, Ointment, Nasal, Spray, metered - Nasal, Spray, metered, Inhalant, Inhalant - Respiratory (inhalation), Respiratory (inhalation), Cream, Solution - Topical, Solution, Cream - Topical, Aerosol, metered - Respiratory (inhalation), Aerosol, metered, Aerosol - Respiratory (inhalation), Aerosol, Intrasinal, Implant - Intrasinal, Implant, Powder, Kit, Kit - Topical, Capsule - Respiratory (inhalation), Capsule, Powder - Respiratory (inhalation), Spray, Spray - Nasal

Seasonal Allergies

, 0.001 mg/mg, 1.0 mg/mL, 0.05 mg, 0.22 mg, 0.11 mg, 0.1 %, 0.2 mg, 0.1 mg, 1.35 mg, 0.01 mg/mg, 1.0 mg, 0.32 mg, 0.08 mg, 0.16 mg, 0.0625 mg, 0.1275 mg, 0.26 mg, 0.136 mg, 0.1 mg/pump actuation, 0.05 mg/spray, 0.2 mg/pump actuation, 0.05 mg/pump actuation, 0.4 mg/pump actuation, 0.025 mg

Ointment - Topical, Topical, , Lotion, Lotion - Topical, Ointment, Nasal, Spray, metered - Nasal, Spray, metered, Inhalant, Inhalant - Respiratory (inhalation), Respiratory (inhalation), Cream, Solution - Topical, Solution, Cream - Topical, Aerosol, metered - Respiratory (inhalation), Aerosol, metered, Aerosol - Respiratory (inhalation), Aerosol, Intrasinal, Implant - Intrasinal, Implant, Powder, Kit, Kit - Topical, Capsule - Respiratory (inhalation), Capsule, Powder - Respiratory (inhalation), Spray, Spray - Nasal

Psoriasis

, 0.001 mg/mg, 1.0 mg/mL, 0.05 mg, 0.22 mg, 0.11 mg, 0.1 %, 0.2 mg, 0.1 mg, 1.35 mg, 0.01 mg/mg, 1.0 mg, 0.32 mg, 0.08 mg, 0.16 mg, 0.0625 mg, 0.1275 mg, 0.26 mg, 0.136 mg, 0.1 mg/pump actuation, 0.05 mg/spray, 0.2 mg/pump actuation, 0.05 mg/pump actuation, 0.4 mg/pump actuation, 0.025 mg

Ointment - Topical, Topical, , Lotion, Lotion - Topical, Ointment, Nasal, Spray, metered - Nasal, Spray, metered, Inhalant, Inhalant - Respiratory (inhalation), Respiratory (inhalation), Cream, Solution - Topical, Solution, Cream - Topical, Aerosol, metered - Respiratory (inhalation), Aerosol, metered, Aerosol - Respiratory (inhalation), Aerosol, Intrasinal, Implant - Intrasinal, Implant, Powder, Kit, Kit - Topical, Capsule - Respiratory (inhalation), Capsule, Powder - Respiratory (inhalation), Spray, Spray - Nasal

Psoriasis

, 0.001 mg/mg, 1.0 mg/mL, 0.05 mg, 0.22 mg, 0.11 mg, 0.1 %, 0.2 mg, 0.1 mg, 1.35 mg, 0.01 mg/mg, 1.0 mg, 0.32 mg, 0.08 mg, 0.16 mg, 0.0625 mg, 0.1275 mg, 0.26 mg, 0.136 mg, 0.1 mg/pump actuation, 0.05 mg/spray, 0.2 mg/pump actuation, 0.05 mg/pump actuation, 0.4 mg/pump actuation, 0.025 mg

Ointment - Topical, Topical, , Lotion, Lotion - Topical, Ointment, Nasal, Spray, metered - Nasal, Spray, metered, Inhalant, Inhalant - Respiratory (inhalation), Respiratory (inhalation), Cream, Solution - Topical, Solution, Cream - Topical, Aerosol, metered - Respiratory (inhalation), Aerosol, metered, Aerosol - Respiratory (inhalation), Aerosol, Intrasinal, Implant - Intrasinal, Implant, Powder, Kit, Kit - Topical, Capsule - Respiratory (inhalation), Capsule, Powder - Respiratory (inhalation), Spray, Spray - Nasal

Skin Diseases, Eczematous

, 0.001 mg/mg, 1.0 mg/mL, 0.05 mg, 0.22 mg, 0.11 mg, 0.1 %, 0.2 mg, 0.1 mg, 1.35 mg, 0.01 mg/mg, 1.0 mg, 0.32 mg, 0.08 mg, 0.16 mg, 0.0625 mg, 0.1275 mg, 0.26 mg, 0.136 mg, 0.1 mg/pump actuation, 0.05 mg/spray, 0.2 mg/pump actuation, 0.05 mg/pump actuation, 0.4 mg/pump actuation, 0.025 mg

Ointment - Topical, Topical, , Lotion, Lotion - Topical, Ointment, Nasal, Spray, metered - Nasal, Spray, metered, Inhalant, Inhalant - Respiratory (inhalation), Respiratory (inhalation), Cream, Solution - Topical, Solution, Cream - Topical, Aerosol, metered - Respiratory (inhalation), Aerosol, metered, Aerosol - Respiratory (inhalation), Aerosol, Intrasinal, Implant - Intrasinal, Implant, Powder, Kit, Kit - Topical, Capsule - Respiratory (inhalation), Capsule, Powder - Respiratory (inhalation), Spray, Spray - Nasal

Communicable Diseases

, 0.001 mg/mg, 1.0 mg/mL, 0.05 mg, 0.22 mg, 0.11 mg, 0.1 %, 0.2 mg, 0.1 mg, 1.35 mg, 0.01 mg/mg, 1.0 mg, 0.32 mg, 0.08 mg, 0.16 mg, 0.0625 mg, 0.1275 mg, 0.26 mg, 0.136 mg, 0.1 mg/pump actuation, 0.05 mg/spray, 0.2 mg/pump actuation, 0.05 mg/pump actuation, 0.4 mg/pump actuation, 0.025 mg

Ointment - Topical, Topical, , Lotion, Lotion - Topical, Ointment, Nasal, Spray, metered - Nasal, Spray, metered, Inhalant, Inhalant - Respiratory (inhalation), Respiratory (inhalation), Cream, Solution - Topical, Solution, Cream - Topical, Aerosol, metered - Respiratory (inhalation), Aerosol, metered, Aerosol - Respiratory (inhalation), Aerosol, Intrasinal, Implant - Intrasinal, Implant, Powder, Kit, Kit - Topical, Capsule - Respiratory (inhalation), Capsule, Powder - Respiratory (inhalation), Spray, Spray - Nasal

Systemic Treatment

, 0.001 mg/mg, 1.0 mg/mL, 0.05 mg, 0.22 mg, 0.11 mg, 0.1 %, 0.2 mg, 0.1 mg, 1.35 mg, 0.01 mg/mg, 1.0 mg, 0.32 mg, 0.08 mg, 0.16 mg, 0.0625 mg, 0.1275 mg, 0.26 mg, 0.136 mg, 0.1 mg/pump actuation, 0.05 mg/spray, 0.2 mg/pump actuation, 0.05 mg/pump actuation, 0.4 mg/pump actuation, 0.025 mg

Ointment - Topical, Topical, , Lotion, Lotion - Topical, Ointment, Nasal, Spray, metered - Nasal, Spray, metered, Inhalant, Inhalant - Respiratory (inhalation), Respiratory (inhalation), Cream, Solution - Topical, Solution, Cream - Topical, Aerosol, metered - Respiratory (inhalation), Aerosol, metered, Aerosol - Respiratory (inhalation), Aerosol, Intrasinal, Implant - Intrasinal, Implant, Powder, Kit, Kit - Topical, Capsule - Respiratory (inhalation), Capsule, Powder - Respiratory (inhalation), Spray, Spray - Nasal

Nasal Decongestants

, 0.001 mg/mg, 1.0 mg/mL, 0.05 mg, 0.22 mg, 0.11 mg, 0.1 %, 0.2 mg, 0.1 mg, 1.35 mg, 0.01 mg/mg, 1.0 mg, 0.32 mg, 0.08 mg, 0.16 mg, 0.0625 mg, 0.1275 mg, 0.26 mg, 0.136 mg, 0.1 mg/pump actuation, 0.05 mg/spray, 0.2 mg/pump actuation, 0.05 mg/pump actuation, 0.4 mg/pump actuation, 0.025 mg

Ointment - Topical, Topical, , Lotion, Lotion - Topical, Ointment, Nasal, Spray, metered - Nasal, Spray, metered, Inhalant, Inhalant - Respiratory (inhalation), Respiratory (inhalation), Cream, Solution - Topical, Solution, Cream - Topical, Aerosol, metered - Respiratory (inhalation), Aerosol, metered, Aerosol - Respiratory (inhalation), Aerosol, Intrasinal, Implant - Intrasinal, Implant, Powder, Kit, Kit - Topical, Capsule - Respiratory (inhalation), Capsule, Powder - Respiratory (inhalation), Spray, Spray - Nasal

Communicable Diseases

, 0.001 mg/mg, 1.0 mg/mL, 0.05 mg, 0.22 mg, 0.11 mg, 0.1 %, 0.2 mg, 0.1 mg, 1.35 mg, 0.01 mg/mg, 1.0 mg, 0.32 mg, 0.08 mg, 0.16 mg, 0.0625 mg, 0.1275 mg, 0.26 mg, 0.136 mg, 0.1 mg/pump actuation, 0.05 mg/spray, 0.2 mg/pump actuation, 0.05 mg/pump actuation, 0.4 mg/pump actuation, 0.025 mg

Ointment - Topical, Topical, , Lotion, Lotion - Topical, Ointment, Nasal, Spray, metered - Nasal, Spray, metered, Inhalant, Inhalant - Respiratory (inhalation), Respiratory (inhalation), Cream, Solution - Topical, Solution, Cream - Topical, Aerosol, metered - Respiratory (inhalation), Aerosol, metered, Aerosol - Respiratory (inhalation), Aerosol, Intrasinal, Implant - Intrasinal, Implant, Powder, Kit, Kit - Topical, Capsule - Respiratory (inhalation), Capsule, Powder - Respiratory (inhalation), Spray, Spray - Nasal

Bacterial Infections

, 0.001 mg/mg, 1.0 mg/mL, 0.05 mg, 0.22 mg, 0.11 mg, 0.1 %, 0.2 mg, 0.1 mg, 1.35 mg, 0.01 mg/mg, 1.0 mg, 0.32 mg, 0.08 mg, 0.16 mg, 0.0625 mg, 0.1275 mg, 0.26 mg, 0.136 mg, 0.1 mg/pump actuation, 0.05 mg/spray, 0.2 mg/pump actuation, 0.05 mg/pump actuation, 0.4 mg/pump actuation, 0.025 mg

Ointment - Topical, Topical, , Lotion, Lotion - Topical, Ointment, Nasal, Spray, metered - Nasal, Spray, metered, Inhalant, Inhalant - Respiratory (inhalation), Respiratory (inhalation), Cream, Solution - Topical, Solution, Cream - Topical, Aerosol, metered - Respiratory (inhalation), Aerosol, metered, Aerosol - Respiratory (inhalation), Aerosol, Intrasinal, Implant - Intrasinal, Implant, Powder, Kit, Kit - Topical, Capsule - Respiratory (inhalation), Capsule, Powder - Respiratory (inhalation), Spray, Spray - Nasal

Psoriasis

, 0.001 mg/mg, 1.0 mg/mL, 0.05 mg, 0.22 mg, 0.11 mg, 0.1 %, 0.2 mg, 0.1 mg, 1.35 mg, 0.01 mg/mg, 1.0 mg, 0.32 mg, 0.08 mg, 0.16 mg, 0.0625 mg, 0.1275 mg, 0.26 mg, 0.136 mg, 0.1 mg/pump actuation, 0.05 mg/spray, 0.2 mg/pump actuation, 0.05 mg/pump actuation, 0.4 mg/pump actuation, 0.025 mg

Ointment - Topical, Topical, , Lotion, Lotion - Topical, Ointment, Nasal, Spray, metered - Nasal, Spray, metered, Inhalant, Inhalant - Respiratory (inhalation), Respiratory (inhalation), Cream, Solution - Topical, Solution, Cream - Topical, Aerosol, metered - Respiratory (inhalation), Aerosol, metered, Aerosol - Respiratory (inhalation), Aerosol, Intrasinal, Implant - Intrasinal, Implant, Powder, Kit, Kit - Topical, Capsule - Respiratory (inhalation), Capsule, Powder - Respiratory (inhalation), Spray, Spray - Nasal

Dermatitis

, 0.001 mg/mg, 1.0 mg/mL, 0.05 mg, 0.22 mg, 0.11 mg, 0.1 %, 0.2 mg, 0.1 mg, 1.35 mg, 0.01 mg/mg, 1.0 mg, 0.32 mg, 0.08 mg, 0.16 mg, 0.0625 mg, 0.1275 mg, 0.26 mg, 0.136 mg, 0.1 mg/pump actuation, 0.05 mg/spray, 0.2 mg/pump actuation, 0.05 mg/pump actuation, 0.4 mg/pump actuation, 0.025 mg

Ointment - Topical, Topical, , Lotion, Lotion - Topical, Ointment, Nasal, Spray, metered - Nasal, Spray, metered, Inhalant, Inhalant - Respiratory (inhalation), Respiratory (inhalation), Cream, Solution - Topical, Solution, Cream - Topical, Aerosol, metered - Respiratory (inhalation), Aerosol, metered, Aerosol - Respiratory (inhalation), Aerosol, Intrasinal, Implant - Intrasinal, Implant, Powder, Kit, Kit - Topical, Capsule - Respiratory (inhalation), Capsule, Powder - Respiratory (inhalation), Spray, Spray - Nasal

Warnings

Sinuva has six contraindications and should not be employed if you are suffering from any of the conditions outlined in the following table.

Sinuva Contraindications

Condition

Risk Level

Notes

Asthma

Do Not Combine

Status Asthmaticus

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Mometasone Furoate may interact with Pulse Frequency

There are 20 known major drug interactions with Sinuva.

Common Sinuva Drug Interactions

Drug Name

Risk Level

Description

Abemaciclib

Major

The metabolism of Abemaciclib can be increased when combined with Mometasone furoate.

Acalabrutinib

Major

The metabolism of Acalabrutinib can be increased when combined with Mometasone furoate.

Aldesleukin

Major

The therapeutic efficacy of Aldesleukin can be decreased when used in combination with Mometasone furoate.

Alectinib

Major

The metabolism of Alectinib can be increased when combined with Mometasone furoate.

Almotriptan

Major

The metabolism of Almotriptan can be decreased when combined with Mometasone furoate.

Sinuva Toxicity & Overdose Risk

Taking too much of a mometasone furoate inhaler may cause symptoms of hypercorticism or adrenal suppression. Animal studies have shown that taking too much can be toxic to a fetus, but humans are not as sensitive to these effects. It is unknown if mometasone furoate is passed into breast milk, so caution should be used when administering to nursing mothers. Children should be prescribed the lowest effective dose of the inhaler, and elderly patients may be more sensitive to its effects. Those with moderate or severe liver impairment may not have detectable concentrations of the drug in their blood, and the effects of the

image of a doctor in a lab doing drug, clinical research

Sinuva Novel Uses: Which Conditions Have a Clinical Trial Featuring Sinuva?

Currently, 279 active studies are analyzing the potential of Sinuva to alleviate Atopic Dermatitis, Seasonal Allergies and Psoriasis.

Condition

Clinical Trials

Trial Phases

Asthma

87 Actively Recruiting

Phase 1, Phase 4, Early Phase 1, Not Applicable, Phase 2, Phase 3

Dermatophytosis

0 Actively Recruiting

Systemic Treatment

0 Actively Recruiting

Seasonal Allergies

0 Actively Recruiting

Itching

3 Actively Recruiting

Phase 3, Not Applicable

Hay Fever

0 Actively Recruiting

Skin Diseases, Eczematous

0 Actively Recruiting

Bacterial Infections

0 Actively Recruiting

Psoriasis

0 Actively Recruiting

prophylaxis of seasonal Allergic rhinitis

0 Actively Recruiting

Dermatitis

0 Actively Recruiting

Psoriasis

0 Actively Recruiting

Psoriasis

0 Actively Recruiting

Communicable Diseases

0 Actively Recruiting

Nasal Decongestants

9 Actively Recruiting

Early Phase 1, Phase 4, Not Applicable, Phase 3, Phase 2

Atopic Dermatitis

12 Actively Recruiting

Phase 2, Phase 3, Phase 4, Not Applicable

Communicable Diseases

0 Actively Recruiting

Sinuva Reviews: What are patients saying about Sinuva?

5

Patient Review

4/14/2021

Sinuva for Presence of Polyps in the Nose

Sinuva has been amazing for me. I've had polyps my whole life and it's really impacted my ability to taste and smell food, but this treatment completely changed that. It was a quick procedure with barely any recovery time, and I'm so grateful to have found something that finally works for me.

1

Patient Review

1/3/2020

Sinuva for Presence of Polyps in the Nose

The implantation process was very unpleasant and caused me a lot of headaches. I have seen no benefits from the treatment whatsoever; my sinuses are still just as stuffed up as before, and I can't smell anything.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about sinuva

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Sinuva FDA approved?

"The company XENT (NASDAQ) dedicated to transforming care for patients with ear, nose and throat conditions, today announced that it has received approval from the U.S. Food and Drug Administration ( FDA ) for the SINUVA™ (mometasone furoate) Sinus Implant, a new targeted approach to treating recurrent nasal polyp ...Dec 11, 2017"

Answered by AI

What is Sinuva used for?

"The SINUVA Sinus Implant is a prescription device that slowly releases the steroid mometasone furoate over a period of time. It is indicated for the treatment of nasal polyps in patients 18 years or older who have had ethmoid sinus surgery."

Answered by AI

Is Sinuva a drug or device?

"The device is a self-expanding, absorbable, sinus implant that is coated with a drugs that help it to expand. The drug is mometasone furoate and it is available in a variety of strengths."

Answered by AI

How long does it take for Sinuva to work?

"The medicine in SINUVA is designed to be released over a period of 90 days, with 80% of the total dosage being released in the first 60 days after placement."

Answered by AI

Clinical Trials for Sinuva

Image of ALS Global in Irving, United States.

GX-03 for Eczema

18 - 70
All Sexes
Irving, TX

This is a randomized, double-blind, vehicle-controlled clinical study designed to evaluate the efficacy and safety of GX-03, a topically applied emollient, in adult subjects with moderate to severe eczema. Approximately 120 adult participants will be enrolled and randomized in a 1:1 ratio to receive either GX-03 or a petrolatum-based vehicle control for 8 consecutive weeks. Efficacy will be assessed using validated clinical outcome measures, including the Eczema Area and Severity Index (EASI), the Validated Investigator Global Assessment for Atopic Dermatitis (vIGA-AD™), and the Peak Pruritus Numeric Rating Scale (PP-NRS). Safety will be evaluated through monitoring of treatment-emergent adverse events throughout the study period.

Phase 2
Recruiting

ALS Global

Turn Therapeutics

Image of Seeding Labs INC in Austin, United States.

Tailored Recommendations for Infant Gut Microbiome

No minimum age - 3
All Sexes
Austin, TX

The goal of this clinical trial is to learn whether microbiome analysis, education, and personalized recommendations can improve gut health and reduce early markers of immune-related conditions in infants aged 0-3 months delivered via Cesarean section. The study aims to determine whether these interventions can increase beneficial bacteria, decrease C-section-associated microbiome signatures, reduce opportunistic pathogens, and improve functional potential for HMO digestion and SCFA production. The study also seeks to assess whether improvements in microbiome composition are associated with a reduced prevalence of early atopic symptoms. Researchers will compare three groups: a full intervention arm that receives microbiome reports, coaching, personalized recommendations, and educational materials; a limited intervention arm that receives simplified reports and basic recommendations; and a control arm that receives no results until study completion. This design allows evaluation of both a comprehensive intervention and a more scalable, minimal-results model. Participants will: 1. Provide six microbiome stool samples over a 24-month period. 2. Provide additional small stool samples at two timepoints for exploratory metabolomic analysis. 3. Receive microbiome reports and guidance according to their assigned study arm. 4. Complete surveys on infant health history, symptoms, diet, and environmental exposures. 5. Participate in standardized eczema assessment(s) administered by a Nurse Practitioner and evaluated by a Pediatric Allergy Specialist if any symptoms are reported. This study seeks to demonstrate that targeted microbiome support can positively shift gut microbial development in C-section infants and may reduce risks linked to the early stages of the atopic march. Findings may inform scalable strategies for delivering microbiome-based support in early life and improve long-term health outcomes for this high-risk population.

Waitlist Available
Has No Placebo

Seeding Labs INC

Qian Yuan, MD

Seeding, Inc DBA Tiny Health

Image of Johns Hopkins Bayview Medical Center in Baltimore, United States.

VR-Enhanced PMR for Post-Burn Symptoms

18+
All Sexes
Baltimore, MD

The goal of this clinical trial is to learn whether progressive muscle relaxation (PMR), delivered either alone or enhanced with virtual reality (VR), can help treat chronic symptom, such as pain, itch, anxiety, sleep disturbances, and fatigue, in adult burn survivors. The main questions it aims to answer are: * Does VR-enhanced PMR (VR-PMR) reduce chronic pain, anxiety, itch, sleep disturbances, and fatigue more effectively than standard PMR? * Is VR-PMR a feasible and acceptable self-administered home-based intervention for burn survivors? Researchers will compare two self-administered intervention conditions, VR-enhanced PMR and standard PMR, using a randomized to sequence crossover design to see if VR technology enhances the therapeutic effects of PMR on chronic symptom management in burn survivors. Participants will: * Complete home-based sessions of VR-enhanced PMR * Complete home-based sessions of standard PMR * Report symptoms such as pain, itch, anxiety, sleep disturbances, and fatigue throughout the study * Use VR equipment provided for the intervention period (during the VR-PMR arm)

Recruiting
Has No Placebo

Johns Hopkins Bayview Medical Center

Sheera Lerman Zohar, PhD

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Have you considered Sinuva clinical trials?

We made a collection of clinical trials featuring Sinuva, we think they might fit your search criteria.
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Image of Allergy Immunology Associates in Mayfield Heights, United States.

Osteopathic Manipulative Treatment for Asthma

18 - 60
All Sexes
Mayfield Heights, OH

Asthma is a common respiratory condition that can be difficult to control despite the use of medications such as inhalers, oral steroids or even injectable medications. Osteopathic Manipulative Treatment (OMT) is a hands-on technique used to improve the chest structure and function and may help in improving breathing. Previous research showed that OMT in asthma patients, can improve the movement of the ribs and improve the "peak flow" which is the maximum rate at which a person can exhale air after taking a deep breath. However, no studies have evaluated the impact of OMT on lung inflammation. This single-site research study at University Hospitals aims to evaluate whether Osteopathic Manipulative Treatment (OMT) can reduce lung inflammation and improve breathing and lung function in adult patients with asthma. The lung function will be evaluated by Spirometry which is a test that measures how much air you can breathe in and out of your lungs, as well as how quickly and easily you can exhale air. The lung inflammation will be measured using a device that can detect how much you are breathing out Nitric Oxide which is a gas produced by inflamed cells in the lungs, this test is called: Fractional exhaled Nitric Oxide or FeNO. Approximately 100 participants will be enrolled.

Waitlist Available
Has No Placebo

Allergy Immunology Associates

Nancy Wasserbauer-Kingston, DO

Image of DARTNet Institute in Aurora, United States.

Inhaled Corticosteroids + Azithromycin for Asthma

13 - 75
All Sexes
Aurora, CO

While asthma therapy is becoming more individualized based on asthma phenotypes, more research is needed to tailor newer therapies to individuals. Inhaled corticosteroid (ICS) medications are the foundation of care for all individuals with persistent asthma. But ICS use is not without possible long term side effects. This study will compare two currently available approaches to reduce AEX in primary care patients: (1) use of inhaled corticosteroids (ICS) as part of rescue therapy, also known as MART (Maintenance And Reliever Therapy) or PARTICS (Patient Activated Reliever Trigger Inhaled Corticosteriods) therapy - either of these therapies will be called Rescue-Inhaled Corticosteroids or R-ICS pronounced "Ricks," and (2) use of azithromycin (AZ) as a preventive therapy. These treatments will be studied both individually and in combination.

Phase 4
Recruiting

DARTNet Institute (+12 Sites)

Wilson D Pace, MD, FAAFP

Image of St. Paul's Hospital in Vancouver, Canada.

Salbutamol for Athletic Performance

18 - 55
All Sexes
Vancouver, Canada

β2-Agonists, commonly used to treat asthma, have also been used by athletes to enhance performance, leading to their ban by the International Olympic Committee in 1972. Research has shown non-asthmatics receive no benefit from these drugs at therapeutic dosages; however, many elite athletes still use them, and asthmatic athletes often win more Olympic medals. In some non-asthmatics, β2-agonists may improve breathing limitations during high intensity exercise, which may improve performance. Therefore, we aim to examine if there is a select group of non-asthmatic individuals who experience breathing limitations that may receive benefit from β2-agonists.

Waitlist Available
Paid Trial

St. Paul's Hospital

Jordan A Guenette, PhD

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