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Podofilox
Perianal Warts, Condylomata Acuminata
Treatment
0 Active Studies for Podofilox
Treatment for
Perianal Warts
What is Podofilox
PodofiloxThe Generic name of this drug
Treatment SummaryPodophyllin is a chemical found in the roots of the podophyllum plant. It is poisonous if taken internally and can cause skin irritation and mucous membrane damage when applied topically. It has been used to treat warts, keratoses, and some skin cancers. It may also have anti-cancer properties.
Condyloxis the brand name
Podofilox Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Condylox
Podofilox
1990
16
Effectiveness
How Podofilox Affects PatientsPodofilox is a more concentrated and stable version of the compound podophyllin. It is used to remove certain types of warts found on the outside skin of the genital area.
How Podofilox works in the bodyThe exact way this drug works is not known, but it seems to target the enzyme topoisomerase II. This enzyme is responsible for forming temporary breaks in the double-stranded DNA molecule so that it can be unwound and replicated. The drug may bind to these breaks and prevent them from being mended, which stops the process of replication from happening.
When to interrupt dosage
The advocated dose of Podofilox is contingent upon the affirmed condition. The measure of dosage fluctuates, based on the outlined technique of administration, specified in the table below.Condition
Dosage
Administration
Perianal Warts
, 5.0 mg/mL, 0.005 mg/mg, 0.5 %
, Solution, Topical, Solution - Topical, Gel - Topical, Gel, Liquid, Liquid - Topical
Condylomata Acuminata
, 5.0 mg/mL, 0.005 mg/mg, 0.5 %
, Solution, Topical, Solution - Topical, Gel - Topical, Gel, Liquid, Liquid - Topical
Podofilox Novel Uses: Which Conditions Have a Clinical Trial Featuring Podofilox?
Currently, there are no active trials examining the potential of Podofilox to attenuate Condylomata Acuminata.Condition
Clinical Trials
Trial Phases
Perianal Warts
0 Actively Recruiting
Condylomata Acuminata
0 Actively Recruiting
Podofilox Reviews: What are patients saying about Podofilox?
5Patient Review
4/15/2016 This treatment is very effective. However, it should not be used for more than three days (six treatments). I found that by the second day, it might be extremely painful for an hour or two after application; however, the pain subsides.
4.3Patient Review
10/8/2021 I've been using this treatment for a while now and I recently noticed that my skin has started peeling off. Has anyone else experienced this?
4.3Patient Review
7/17/2022 Though it burns, this treatment is working well for me and beats out Imiquimod which I tried months ago to no avail. The only downside is that the application process isn't very precise.
4Patient Review
7/4/2022 This treatment is effective, but incredibly painful. I was only able to use it for two days before the pain became too much. On the plus side, by the fifth day most of the discomfort had subsided.
4Patient Review
6/4/2022 I've been using this medication for half a year, but only now that I'm following the directions to a tee am I seeing results. In just two days, I can already see an improvement.
3.7Patient Review
4/12/2022 Yes, this treatment stings quite a bit. However, it seems to be working and the warts are going away. I have noticed more discharge and odor, but nothing unbearable.
3.3Patient Review
3/22/2018 This treatment was incredibly painful and uncomfortable. I couldn't sleep for two days straight because of it. It's also very easy to apply, but you need to be careful with how much you use.
3.3Patient Review
1/26/2022 This treatment really burns, like others have said. I was too desperate to get rid of my genital warts, so I applied it for four days in a row instead of the recommended three. Now I'm paying the price; it still hurts a lot and I can barely move without being in pain. But at least the warts are gone!
3Patient Review
12/5/2016 I've been taking this medication for over a year without any results. I'm not sure what else to try and it's frustrating that it doesn't seem to be working. If anyone has any advice, I would appreciate it.
2.3Patient Review
2/10/2019 I've been using this treatment for three days, with the next four being a resting period. So far I haven't seen any results and am wondering if I should go back to my doctor. I'm also curious as to whether or not I'm applying it correctly. Usually, I just squeeze the tube until there's enough liquid to cover the wart. After that, am I supposed to wait for it to dry before putting my pants back on? Or should I use a bandaid? Either way, patience is probably key here.
2.3Patient Review
3/5/2022 I completed the full six applications over three days. I can say with certainty that I will not be doing this again. The burning sensation was unbearable and now I have redness on healthy skin that has turned white. Additionally, my skin feels like it's about to crack open and bleed. The pain is so severe that I haven't been able to get a decent night's sleep. There has been very slight change in the color of the genital warts, but not enough to warrant continuing treatment. At one point, the pain was so bad that I considered going to the emergency room.
2.3Patient Review
2/1/2018 I couldn't make it to the end of the recommended treatment period because the burning was too much. I don't know if that means it would have eventually worked or not, but I do know that living with a burning penis is not something I'm willing to do.
1.7Patient Review
5/1/2019 I am on day two of week two and the pain is so bad that I can barely walk. I don't know if I will be able to make it to day three, let alone week four. The medicated powder helps just a little bit, but not much. This hurts a lot!
Patient Q&A Section about podofilox
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is podofilox used to treat?
"Podofilox is a medication used to remove warts on the skin in the genital area. It can also be used to treat warts between the genitals and the rectum. However, the solution cannot be used for this purpose."
Answered by AI
Can I buy podofilox over the counter?
"No, podofilox (Condylox) requires a prescription from your provider."
Answered by AI
How quickly does podofilox work?
"If you don't see improvement in your symptoms within a week, new warts may have developed and you should tell your doctor. The course of treatment can be repeated up to four times a week."
Answered by AI
How long do you use podofilox?
"Apply the medication to the wart(s) two times a day, every twelve hours, for three days. Then, skip four days by not applying the medication. If the wart can still be seen, repeat this process for up to four weeks, until the wart is gone."
Answered by AI
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