Pitavastatin Calcium
Hyperlipidemia, Hypercholesterolemia, Dyslipidemias
Treatment
5 FDA approvals
5 Active Studies for Pitavastatin Calcium
Treatment for
Hyperlipidemia
What is Pitavastatin Calcium
Pitavastatin
The Generic name of this drug
Treatment Summary
Pitavastatin, also known as Livalo, is a cholesterol-lowering drug from the statin class. It works by blocking an enzyme in the liver that helps produce cholesterol. Statins are typically prescribed for people who have had a cardiovascular event or have a moderate to high risk of developing cardiovascular disease (CVD). Studies have shown that statins can help lower bad cholesterol (LDL) levels and reduce the risk of CVD. Pitavastatin is one of the most commonly prescribed statins and has been found to be as effective as other statins in reducing LDL levels and increasing good cholesterol (HDL)
Livalo
is the brand name
Pitavastatin Calcium Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Livalo
Pitavastatin
2010
21
Approved as Treatment by the FDA
Pitavastatin, also called Livalo, is approved by the FDA for 5 uses including Heterozygous Familial Hypercholesterolemia (HeFH) and primary Hyperlipidemia .
Heterozygous Familial Hypercholesterolemia (HeFH)
primary Hyperlipidemia
Helps manage primary Hyperlipidemia
Hypercholesterolemia
Hyperlipidemia
Helps manage primary Hyperlipidemia
Dyslipidemias
Helps manage Mixed Dyslipidemias
Effectiveness
How Pitavastatin Calcium Affects Patients
Pitavastatin is a medication used to reduce cholesterol levels in the body. It lowers total cholesterol, LDL (bad) cholesterol, non-HDL cholesterol, and triglycerides while increasing HDL (good) cholesterol. High LDL cholesterol and low HDL cholesterol can increase the risk of developing coronary artery disease and other cardiovascular problems. Pitavastatin helps to lower these risks by decreasing LDL and increasing HDL. Long-term use of pitavastatin can cause muscle pain, tenderness, or weakness, as well as rhabdomyolysis (muscle breakdown) in rare cases. It is important to take the
How Pitavastatin Calcium works in the body
Pitavastatin is a medication that works to reduce cholesterol levels in the body. It does this by blocking an enzyme in the liver that helps make cholesterol. Blocking this enzyme reduces the amount of cholesterol circulating in the body. This medication also has additional benefits. It can help improve the function of blood vessels, reduce inflammation, and prevent blood clots. Finally, it can bind to molecules in the body that help control how white blood cells move around and how T-cells become activated.
When to interrupt dosage
The measure of Pitavastatin Calcium is reliant upon the recognized condition, including Hyperlipidemia, Hypercholesterolemia and Dyslipidemias. The amount of dosage is contingent upon the approach of delivery (e.g. Tablet, film coated - Oral or Tablet, film coated) featured in the table beneath.
Condition
Dosage
Administration
Hyperlipidemia
2.0 mg, 4.0 mg, , 1.0 mg, 2.09 mg, 1.045 mg, 4.18 mg
Tablet, film coated, Tablet, film coated - Oral, , Oral
Hypercholesterolemia
2.0 mg, 4.0 mg, , 1.0 mg, 2.09 mg, 1.045 mg, 4.18 mg
Tablet, film coated, Tablet, film coated - Oral, , Oral
Dyslipidemias
2.0 mg, 4.0 mg, , 1.0 mg, 2.09 mg, 1.045 mg, 4.18 mg
Tablet, film coated, Tablet, film coated - Oral, , Oral
Warnings
Pitavastatin Calcium Contraindications
Condition
Risk Level
Notes
Breast Milk Production
Do Not Combine
Liver Diseases
Do Not Combine
Transaminases
Do Not Combine
Pulse Frequency
Do Not Combine
There are 20 known major drug interactions with Pitavastatin Calcium.
Common Pitavastatin Calcium Drug Interactions
Drug Name
Risk Level
Description
Brigatinib
Major
The metabolism of Brigatinib can be decreased when combined with Pitavastatin.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Pitavastatin.
Enasidenib
Major
The metabolism of Enasidenib can be decreased when combined with Pitavastatin.
Fluorouracil
Major
The metabolism of Fluorouracil can be decreased when combined with Pitavastatin.
Fosphenytoin
Major
The metabolism of Fosphenytoin can be decreased when combined with Pitavastatin.
Pitavastatin Calcium Novel Uses: Which Conditions Have a Clinical Trial Featuring Pitavastatin Calcium?
Presently, 6 active studies are examining the potential of Pitavastatin Calcium in the management of Dyslipidemias, Hyperlipidemia and Hypercholesterolemia.
Condition
Clinical Trials
Trial Phases
Hypercholesterolemia
4 Actively Recruiting
Phase 1, Phase 3
Hyperlipidemia
0 Actively Recruiting
Dyslipidemias
1 Actively Recruiting
Phase 2
Pitavastatin Calcium Reviews: What are patients saying about Pitavastatin Calcium?
5
Patient Review
6/11/2013
Pitavastatin Calcium for High Cholesterol
2.3
Patient Review
5/10/2011
Pitavastatin Calcium for High Cholesterol
2
Patient Review
8/6/2014
Pitavastatin Calcium for High Cholesterol
Patient Q&A Section about pitavastatin calcium
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Is pitavastatin better than rosuvastatin?
"The average dose of rosuvastatin per day was 2.5 milligrams and the average dose of pitavastatin per day was 1.4 milligrams. All lipid parameters were significantly more improved in the rosuvastatin group. The rosuvastatin group's eGFR improved from baseline (p ＜ 0.0001) and showed no tendency to worsen in the pitavastatin group (p=0.2232)."
Answered by AI
What is pitavastatin calcium used for?
"Pitavastatin is a drug that is used to reduce cholesterol. It works by reducing the production of cholesterol in the body, which can build up on the walls of the arteries and block blood flow to the heart, brain, and other parts of the body."
Answered by AI
Is pitavastatin calcium a statin?
"Pitavastatin calcium is a new statin that has been approved for use in the United States for the treatment of primary hyperlipidemia and mixed dyslipidemia."
Answered by AI
What are the side effects of pitavastatin?
"You may experience muscle pain, back pain, joint pain, pain in your arms and legs, diarrhea, constipation, skin rash, or headache."
Answered by AI