Pitavastatin Calcium

Q: What is pitavastatin calcium used for?

<p>Pitavastatin is a drug that is used to reduce <a href="https://www.withpower.com/clinical-trials/cholesterol">cholesterol</a>. It works by reducing the production of cholesterol in the body, which can build up on the walls of the arteries and block blood flow to the heart, brain, and other parts of the body.</p>

Q: What are the side effects of pitavastatin?

<p>You may experience muscle pain, <a href="https://www.withpower.com/clinical-trials/back-pain">back pain</a>, joint pain, pain in your arms and legs, diarrhea, constipation, skin rash, or headache.</p>

Hyperlipidemia, Hypercholesterolemia, Dyslipidemias

Treatment

5 FDA approvals

3 Active Studies for Pitavastatin Calcium

Treatment for

Hyperlipidemia

What is Pitavastatin Calcium

PitavastatinThe Generic name of this drug

Treatment SummaryPitavastatin, also known as Livalo, is a cholesterol-lowering drug from the statin class. It works by blocking an enzyme in the liver that helps produce cholesterol. Statins are typically prescribed for people who have had a cardiovascular event or have a moderate to high risk of developing cardiovascular disease (CVD). Studies have shown that statins can help lower bad cholesterol (LDL) levels and reduce the risk of CVD. Pitavastatin is one of the most commonly prescribed statins and has been found to be as effective as other statins in reducing LDL levels and increasing good cholesterol (HDL)

Livalois the brand name

image of different drug pills on a surface

Pitavastatin Calcium Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Livalo

Pitavastatin

2010

Approved as Treatment by the FDA

Pitavastatin, also called Livalo, is approved by the FDA for 5 uses including Heterozygous Familial Hypercholesterolemia (HeFH) and primary Hyperlipidemia .

Heterozygous Familial Hypercholesterolemia (HeFH)

primary Hyperlipidemia

Helps manage primary Hyperlipidemia

Hypercholesterolemia

Hyperlipidemia

Helps manage primary Hyperlipidemia

Dyslipidemias

Helps manage Mixed Dyslipidemias

Effectiveness

How Pitavastatin Calcium Affects PatientsPitavastatin is a medication used to reduce cholesterol levels in the body. It lowers total cholesterol, LDL (bad) cholesterol, non-HDL cholesterol, and triglycerides while increasing HDL (good) cholesterol. High LDL cholesterol and low HDL cholesterol can increase the risk of developing coronary artery disease and other cardiovascular problems. Pitavastatin helps to lower these risks by decreasing LDL and increasing HDL. Long-term use of pitavastatin can cause muscle pain, tenderness, or weakness, as well as rhabdomyolysis (muscle breakdown) in rare cases. It is important to take the

How Pitavastatin Calcium works in the bodyPitavastatin is a medication that works to reduce cholesterol levels in the body. It does this by blocking an enzyme in the liver that helps make cholesterol. Blocking this enzyme reduces the amount of cholesterol circulating in the body. This medication also has additional benefits. It can help improve the function of blood vessels, reduce inflammation, and prevent blood clots. Finally, it can bind to molecules in the body that help control how white blood cells move around and how T-cells become activated.

When to interrupt dosage

The measure of Pitavastatin Calcium is reliant upon the recognized condition, including Hyperlipidemia, Hypercholesterolemia and Dyslipidemias. The amount of dosage is contingent upon the approach of delivery (e.g. Tablet, film coated - Oral or Tablet, film coated) featured in the table beneath.

Condition

Dosage

Administration

Hyperlipidemia

2.0 mg, 4.0 mg, , 1.0 mg, 2.09 mg, 1.045 mg, 4.18 mg

Tablet, film coated, Oral, , Tablet, film coated - Oral

Hypercholesterolemia

2.0 mg, 4.0 mg, , 1.0 mg, 2.09 mg, 1.045 mg, 4.18 mg

Tablet, film coated, Oral, , Tablet, film coated - Oral

Dyslipidemias

2.0 mg, 4.0 mg, , 1.0 mg, 2.09 mg, 1.045 mg, 4.18 mg

Tablet, film coated, Oral, , Tablet, film coated - Oral

Warnings

Pitavastatin Calcium Contraindications

Condition

Risk Level

Notes

Breast Milk Production

Do Not Combine

Liver Diseases

Do Not Combine

Transaminases

Do Not Combine

Pulse Frequency

Do Not Combine

There are 20 known major drug interactions with Pitavastatin Calcium.

Common Pitavastatin Calcium Drug Interactions

Drug Name

Risk Level

Description

Brigatinib

Major

The metabolism of Brigatinib can be decreased when combined with Pitavastatin.

Cabazitaxel

Major

The metabolism of Cabazitaxel can be decreased when combined with Pitavastatin.

Enasidenib

Major

The metabolism of Enasidenib can be decreased when combined with Pitavastatin.

Fluorouracil

Major

The metabolism of Fluorouracil can be decreased when combined with Pitavastatin.

Fosphenytoin

Major

The metabolism of Fosphenytoin can be decreased when combined with Pitavastatin.

image of a doctor in a lab doing drug, clinical research

Pitavastatin Calcium Novel Uses: Which Conditions Have a Clinical Trial Featuring Pitavastatin Calcium?

Presently, 6 active studies are examining the potential of Pitavastatin Calcium in the management of Dyslipidemias, Hyperlipidemia and Hypercholesterolemia.

Condition

Clinical Trials

Trial Phases

Hypercholesterolemia

2 Actively Recruiting

Phase 1, Phase 3

Hyperlipidemia

0 Actively Recruiting

Dyslipidemias

1 Actively Recruiting

Phase 2

Pitavastatin Calcium Reviews: What are patients saying about Pitavastatin Calcium?

5Patient Review

6/11/2013

Pitavastatin Calcium for High Cholesterol

I had taken Cretor and Lipitor before, but both of those caused me to feel very tired and weak. Livalo doesn't have any of those side effects, and it's lowered my cholesterol significantly.

2.3Patient Review

5/10/2011

Pitavastatin Calcium for High Cholesterol

I was on this medication for two years, but my stroke doctor instructed me to switch to crestor. I was taking 80mg of prevastatin.

2Patient Review

8/6/2014

Pitavastatin Calcium for High Cholesterol

I'm going to need to change treatments after two years of taking this one. I've had too many issues this past year.

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Patient Q&A Section about pitavastatin calcium

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is pitavastatin better than rosuvastatin?

"The average dose of rosuvastatin per day was 2.5 milligrams and the average dose of pitavastatin per day was 1.4 milligrams. All lipid parameters were significantly more improved in the rosuvastatin group. The rosuvastatin group's eGFR improved from baseline (p ＜ 0.0001) and showed no tendency to worsen in the pitavastatin group (p=0.2232)."

Answered by AI

What is pitavastatin calcium used for?

"Pitavastatin is a drug that is used to reduce cholesterol. It works by reducing the production of cholesterol in the body, which can build up on the walls of the arteries and block blood flow to the heart, brain, and other parts of the body."

Answered by AI

Is pitavastatin calcium a statin?

"Pitavastatin calcium is a new statin that has been approved for use in the United States for the treatment of primary hyperlipidemia and mixed dyslipidemia."

Answered by AI