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What is Oxistat
OxiconazoleThe Generic name of this drug
Treatment SummaryOxiconazole is a medication used to treat fungal skin infections such as athlete's foot, jock itch, and ringworm. It is available in topical formulations and sold under the brand names Oxistat and Oxistat.
Oxistatis the brand name
Oxistat Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Oxistat
Oxiconazole
1988
11
Approved as Treatment by the FDA
Oxiconazole, also called Oxistat, is approved by the FDA for 6 uses including Malassezia and Tinea cruris .Malassezia
Tinea cruris
Cellulitis
Pityriasis versicolor
Tinea Pedis
Tinea Corporis
Effectiveness
How Oxistat Affects PatientsOxiconazole is a drug used to treat fungal infections. It works by blocking the production of a certain molecule (ergosterol) that is necessary for the fungus to survive and grow. This drug has been shown to be effective against several types of fungi, including the dermatophytes and yeasts like Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Trichophyton violaceum, Epidermophyton floccosum, Microsporum canis, Microsporum audouinii, Microsporum gyp
How Oxistat works in the bodyOxiconazole prevents fungi from forming a cell membrane. It does this by targeting a specific enzyme that is necessary for the formation of the membrane. Without this membrane, the fungus is unable to survive and will die. Oxiconazole also stops the fungus from producing DNA and energy, making it even more difficult for the fungus to survive. Oxiconazole also makes the cell more permeable to zinc, which has toxic effects on the fungus.
When to interrupt dosage
The dosage of Oxistat is contingent on the recognized condition, encompassing Cellulitis, Tinea cruris and Malassezia. The amount of dosage changes, based on the system of delivery noted in the table below.Condition
Dosage
Administration
Tinea Corporis
0.01 mg/mg, , 0.03 mg/mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Lotion, Lotion - Topical
Pityriasis versicolor
0.01 mg/mg, , 0.03 mg/mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Lotion, Lotion - Topical
Malassezia
0.01 mg/mg, , 0.03 mg/mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Lotion, Lotion - Topical
Tinea Pedis
0.01 mg/mg, , 0.03 mg/mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Lotion, Lotion - Topical
Cellulitis
0.01 mg/mg, , 0.03 mg/mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Lotion, Lotion - Topical
Tinea cruris
0.01 mg/mg, , 0.03 mg/mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Lotion, Lotion - Topical
Warnings
There are 10 known major drug interactions with Oxistat.Common Oxistat Drug Interactions
Drug Name
Risk Level
Description
Capmatinib
Major
The serum concentration of Capmatinib can be decreased when it is combined with Oxiconazole.
Lumateperone
Major
The serum concentration of Lumateperone can be decreased when it is combined with Oxiconazole.
Ranolazine
Major
The metabolism of Ranolazine can be increased when combined with Oxiconazole.
Rimegepant
Major
The metabolism of Rimegepant can be increased when combined with Oxiconazole.
Tivozanib
Major
The metabolism of Tivozanib can be increased when combined with Oxiconazole.
Oxistat Toxicity & Overdose RiskSide effects of this drug include itching, burning, redness, stinging, and allergic skin reactions such as bumps and rashes.
Oxistat Novel Uses: Which Conditions Have a Clinical Trial Featuring Oxistat?
No active studies are currently assessing the potential of Oxistat to provide relief from Pityriasis versicolor, Cellulitis and Tinea Pedis.Condition
Clinical Trials
Trial Phases
Tinea Corporis
0 Actively Recruiting
Pityriasis versicolor
0 Actively Recruiting
Cellulitis
0 Actively Recruiting
Tinea cruris
0 Actively Recruiting
Malassezia
0 Actively Recruiting
Tinea Pedis
0 Actively Recruiting
Oxistat Reviews: What are patients saying about Oxistat?
5Patient Review
3/5/20085Patient Review
9/2/2008 I've found this to be a really effective solution for when my eczema flares up, especially on my face and scalp.
4Patient Review
3/11/2009 I found this lotion to be effective, even though it gets wiped off by socks. I would recommend using a bandaid with it, even though the instructions say not to.
2.3Patient Review
4/10/2014 Oxistat did little more than provide temporary relief from the itching. In other words, it didn't really help me that much and failed to cure the infection.
Patient Q&A Section about oxistat
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Oxistat over the counter?
"Even though it is available over-the-counter, Oxistat (oxiconazole) is more expensive than other antifungals. For treating athlete's foot, there are other antifungals that might work better."
Answered by AI
Is Oxistat used for yeast infection?
"The medicine oxiconazole is used to treat fungal infections of the skin."
Answered by AI
How long does it take for Oxistat to work?
"For ringworm, jock itch, and tinea versicolor, you can expect to see results from Oxistat (oxiconazole) within 2 weeks. For athlete's foot, you can expect to see results within a month."
Answered by AI
What is Oxistat cream used for?
"This medication is used to treat various types of skin infections and also to treat pityriasis, a fungal infection that causes the skin to lighten or darken."
Answered by AI