Nocdurna

Polyuria, Nocturia, Polydipsia + 14 more

Treatment

18 Active Studies for Nocdurna

What is Nocdurna

Desmopressin

The Generic name of this drug

Treatment Summary

Desmopressin (dDAVP), is a drug that mimics a hormone made by the pituitary gland. It works by helping the body retain water, which helps to control the amount of water in the body. Desmopressin is used to treat polyuric conditions like primary nocturnal enuresis, nocturia, diabetes insipidus, mild classical hemophilia, and von Willebrand's disease. It was approved by the FDA in 1972 and is available in various forms, including intranasal solution, intravenous solution, oral tablet and oral lyophilisate. N

Ddavp

is the brand name

image of different drug pills on a surface

Nocdurna Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Ddavp

Desmopressin

1978

101

Effectiveness

How Nocdurna Affects Patients

Desmopressin is a drug that acts like a natural hormone in the body, called antidiuretic hormone (ADH), to reduce urine production. It is more effective than ADH in increasing factor VIII activity in people with hemophilia and von Willebrand's disease Type I. It has a much weaker effect when taken by nasal spray instead of injection.

How Nocdurna works in the body

When desmopressin binds to certain receptors in the kidneys, it triggers a series of reactions that cause more water channels to form in the kidney cells. These channels make it easier for water to pass into the cells.

When to interrupt dosage

The endorsed dose of Nocdurna is contingent upon the diagnosed condition, such as Minor Surgical Procedures, Pituitary Gland and Surgery, Hemophilia A. The quantity of dosage shifts, as per the delivery system featured in the table beneath.

Condition

Dosage

Administration

Nocturia

0.1 mg, 0.2 mg, , 0.1 mg/mL, 0.004 mg/mL, 0.0001 mg/mL, 0.01 mg, 0.06 mg, 0.12 mg, 0.24 mg, 0.025 mg, 0.05 mg, 1.5 mg/mL, 0.00083 mg, 0.00166 mg, 0.0277 mg, 0.0553 mg, 0.015 mg/mL, 0.01 mg/pump actuation, 0.15 mg/pump actuation

Oral, , Tablet - Oral, Tablet, Nasal, Solution, Solution - Nasal, Solution - Intravenous, Intravenous, Injection, solution - Intravenous; Subcutaneous, Injection - Intravenous, Injection, Spray - Nasal, Intramuscular; Intravenous; Subcutaneous, Liquid - Intramuscular; Intravenous; Subcutaneous, Liquid, Spray, metered - Nasal, Spray, metered, Sublingual, Tablet, orally disintegrating - Sublingual, Tablet, orally disintegrating, Aerosol, metered - Nasal, Aerosol, metered, Tablet - Sublingual, Spray, Injection, solution, Injection - Intravenous; Subcutaneous, Solution - Intramuscular; Intravenous; Subcutaneous, Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous

Polydipsia

0.1 mg, 0.2 mg, , 0.1 mg/mL, 0.004 mg/mL, 0.0001 mg/mL, 0.01 mg, 0.06 mg, 0.12 mg, 0.24 mg, 0.025 mg, 0.05 mg, 1.5 mg/mL, 0.00083 mg, 0.00166 mg, 0.0277 mg, 0.0553 mg, 0.015 mg/mL, 0.01 mg/pump actuation, 0.15 mg/pump actuation

Oral, , Tablet - Oral, Tablet, Nasal, Solution, Solution - Nasal, Solution - Intravenous, Intravenous, Injection, solution - Intravenous; Subcutaneous, Injection - Intravenous, Injection, Spray - Nasal, Intramuscular; Intravenous; Subcutaneous, Liquid - Intramuscular; Intravenous; Subcutaneous, Liquid, Spray, metered - Nasal, Spray, metered, Sublingual, Tablet, orally disintegrating - Sublingual, Tablet, orally disintegrating, Aerosol, metered - Nasal, Aerosol, metered, Tablet - Sublingual, Spray, Injection, solution, Injection - Intravenous; Subcutaneous, Solution - Intramuscular; Intravenous; Subcutaneous, Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous

von Willebrand Disease

0.1 mg, 0.2 mg, , 0.1 mg/mL, 0.004 mg/mL, 0.0001 mg/mL, 0.01 mg, 0.06 mg, 0.12 mg, 0.24 mg, 0.025 mg, 0.05 mg, 1.5 mg/mL, 0.00083 mg, 0.00166 mg, 0.0277 mg, 0.0553 mg, 0.015 mg/mL, 0.01 mg/pump actuation, 0.15 mg/pump actuation

Oral, , Tablet - Oral, Tablet, Nasal, Solution, Solution - Nasal, Solution - Intravenous, Intravenous, Injection, solution - Intravenous; Subcutaneous, Injection - Intravenous, Injection, Spray - Nasal, Intramuscular; Intravenous; Subcutaneous, Liquid - Intramuscular; Intravenous; Subcutaneous, Liquid, Spray, metered - Nasal, Spray, metered, Sublingual, Tablet, orally disintegrating - Sublingual, Tablet, orally disintegrating, Aerosol, metered - Nasal, Aerosol, metered, Tablet - Sublingual, Spray, Injection, solution, Injection - Intravenous; Subcutaneous, Solution - Intramuscular; Intravenous; Subcutaneous, Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous

Hemophilia A

0.1 mg, 0.2 mg, , 0.1 mg/mL, 0.004 mg/mL, 0.0001 mg/mL, 0.01 mg, 0.06 mg, 0.12 mg, 0.24 mg, 0.025 mg, 0.05 mg, 1.5 mg/mL, 0.00083 mg, 0.00166 mg, 0.0277 mg, 0.0553 mg, 0.015 mg/mL, 0.01 mg/pump actuation, 0.15 mg/pump actuation

Oral, , Tablet - Oral, Tablet, Nasal, Solution, Solution - Nasal, Solution - Intravenous, Intravenous, Injection, solution - Intravenous; Subcutaneous, Injection - Intravenous, Injection, Spray - Nasal, Intramuscular; Intravenous; Subcutaneous, Liquid - Intramuscular; Intravenous; Subcutaneous, Liquid, Spray, metered - Nasal, Spray, metered, Sublingual, Tablet, orally disintegrating - Sublingual, Tablet, orally disintegrating, Aerosol, metered - Nasal, Aerosol, metered, Tablet - Sublingual, Spray, Injection, solution, Injection - Intravenous; Subcutaneous, Solution - Intramuscular; Intravenous; Subcutaneous, Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous

Pituitary Diseases

0.1 mg, 0.2 mg, , 0.1 mg/mL, 0.004 mg/mL, 0.0001 mg/mL, 0.01 mg, 0.06 mg, 0.12 mg, 0.24 mg, 0.025 mg, 0.05 mg, 1.5 mg/mL, 0.00083 mg, 0.00166 mg, 0.0277 mg, 0.0553 mg, 0.015 mg/mL, 0.01 mg/pump actuation, 0.15 mg/pump actuation

Oral, , Tablet - Oral, Tablet, Nasal, Solution, Solution - Nasal, Solution - Intravenous, Intravenous, Injection, solution - Intravenous; Subcutaneous, Injection - Intravenous, Injection, Spray - Nasal, Intramuscular; Intravenous; Subcutaneous, Liquid - Intramuscular; Intravenous; Subcutaneous, Liquid, Spray, metered - Nasal, Spray, metered, Sublingual, Tablet, orally disintegrating - Sublingual, Tablet, orally disintegrating, Aerosol, metered - Nasal, Aerosol, metered, Tablet - Sublingual, Spray, Injection, solution, Injection - Intravenous; Subcutaneous, Solution - Intramuscular; Intravenous; Subcutaneous, Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous

Uremia

0.1 mg, 0.2 mg, , 0.1 mg/mL, 0.004 mg/mL, 0.0001 mg/mL, 0.01 mg, 0.06 mg, 0.12 mg, 0.24 mg, 0.025 mg, 0.05 mg, 1.5 mg/mL, 0.00083 mg, 0.00166 mg, 0.0277 mg, 0.0553 mg, 0.015 mg/mL, 0.01 mg/pump actuation, 0.15 mg/pump actuation

Oral, , Tablet - Oral, Tablet, Nasal, Solution, Solution - Nasal, Solution - Intravenous, Intravenous, Injection, solution - Intravenous; Subcutaneous, Injection - Intravenous, Injection, Spray - Nasal, Intramuscular; Intravenous; Subcutaneous, Liquid - Intramuscular; Intravenous; Subcutaneous, Liquid, Spray, metered - Nasal, Spray, metered, Sublingual, Tablet, orally disintegrating - Sublingual, Tablet, orally disintegrating, Aerosol, metered - Nasal, Aerosol, metered, Tablet - Sublingual, Spray, Injection, solution, Injection - Intravenous; Subcutaneous, Solution - Intramuscular; Intravenous; Subcutaneous, Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous

Hemorrhage

0.1 mg, 0.2 mg, , 0.1 mg/mL, 0.004 mg/mL, 0.0001 mg/mL, 0.01 mg, 0.06 mg, 0.12 mg, 0.24 mg, 0.025 mg, 0.05 mg, 1.5 mg/mL, 0.00083 mg, 0.00166 mg, 0.0277 mg, 0.0553 mg, 0.015 mg/mL, 0.01 mg/pump actuation, 0.15 mg/pump actuation

Oral, , Tablet - Oral, Tablet, Nasal, Solution, Solution - Nasal, Solution - Intravenous, Intravenous, Injection, solution - Intravenous; Subcutaneous, Injection - Intravenous, Injection, Spray - Nasal, Intramuscular; Intravenous; Subcutaneous, Liquid - Intramuscular; Intravenous; Subcutaneous, Liquid, Spray, metered - Nasal, Spray, metered, Sublingual, Tablet, orally disintegrating - Sublingual, Tablet, orally disintegrating, Aerosol, metered - Nasal, Aerosol, metered, Tablet - Sublingual, Spray, Injection, solution, Injection - Intravenous; Subcutaneous, Solution - Intramuscular; Intravenous; Subcutaneous, Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous

von Willebrand Disease

0.1 mg, 0.2 mg, , 0.1 mg/mL, 0.004 mg/mL, 0.0001 mg/mL, 0.01 mg, 0.06 mg, 0.12 mg, 0.24 mg, 0.025 mg, 0.05 mg, 1.5 mg/mL, 0.00083 mg, 0.00166 mg, 0.0277 mg, 0.0553 mg, 0.015 mg/mL, 0.01 mg/pump actuation, 0.15 mg/pump actuation

Oral, , Tablet - Oral, Tablet, Nasal, Solution, Solution - Nasal, Solution - Intravenous, Intravenous, Injection, solution - Intravenous; Subcutaneous, Injection - Intravenous, Injection, Spray - Nasal, Intramuscular; Intravenous; Subcutaneous, Liquid - Intramuscular; Intravenous; Subcutaneous, Liquid, Spray, metered - Nasal, Spray, metered, Sublingual, Tablet, orally disintegrating - Sublingual, Tablet, orally disintegrating, Aerosol, metered - Nasal, Aerosol, metered, Tablet - Sublingual, Spray, Injection, solution, Injection - Intravenous; Subcutaneous, Solution - Intramuscular; Intravenous; Subcutaneous, Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous

Hemorrhage

0.1 mg, 0.2 mg, , 0.1 mg/mL, 0.004 mg/mL, 0.0001 mg/mL, 0.01 mg, 0.06 mg, 0.12 mg, 0.24 mg, 0.025 mg, 0.05 mg, 1.5 mg/mL, 0.00083 mg, 0.00166 mg, 0.0277 mg, 0.0553 mg, 0.015 mg/mL, 0.01 mg/pump actuation, 0.15 mg/pump actuation

Oral, , Tablet - Oral, Tablet, Nasal, Solution, Solution - Nasal, Solution - Intravenous, Intravenous, Injection, solution - Intravenous; Subcutaneous, Injection - Intravenous, Injection, Spray - Nasal, Intramuscular; Intravenous; Subcutaneous, Liquid - Intramuscular; Intravenous; Subcutaneous, Liquid, Spray, metered - Nasal, Spray, metered, Sublingual, Tablet, orally disintegrating - Sublingual, Tablet, orally disintegrating, Aerosol, metered - Nasal, Aerosol, metered, Tablet - Sublingual, Spray, Injection, solution, Injection - Intravenous; Subcutaneous, Solution - Intramuscular; Intravenous; Subcutaneous, Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous

Hemophilia A

0.1 mg, 0.2 mg, , 0.1 mg/mL, 0.004 mg/mL, 0.0001 mg/mL, 0.01 mg, 0.06 mg, 0.12 mg, 0.24 mg, 0.025 mg, 0.05 mg, 1.5 mg/mL, 0.00083 mg, 0.00166 mg, 0.0277 mg, 0.0553 mg, 0.015 mg/mL, 0.01 mg/pump actuation, 0.15 mg/pump actuation

Oral, , Tablet - Oral, Tablet, Nasal, Solution, Solution - Nasal, Solution - Intravenous, Intravenous, Injection, solution - Intravenous; Subcutaneous, Injection - Intravenous, Injection, Spray - Nasal, Intramuscular; Intravenous; Subcutaneous, Liquid - Intramuscular; Intravenous; Subcutaneous, Liquid, Spray, metered - Nasal, Spray, metered, Sublingual, Tablet, orally disintegrating - Sublingual, Tablet, orally disintegrating, Aerosol, metered - Nasal, Aerosol, metered, Tablet - Sublingual, Spray, Injection, solution, Injection - Intravenous; Subcutaneous, Solution - Intramuscular; Intravenous; Subcutaneous, Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous

Diabetes Insipidus, Neurogenic

0.1 mg, 0.2 mg, , 0.1 mg/mL, 0.004 mg/mL, 0.0001 mg/mL, 0.01 mg, 0.06 mg, 0.12 mg, 0.24 mg, 0.025 mg, 0.05 mg, 1.5 mg/mL, 0.00083 mg, 0.00166 mg, 0.0277 mg, 0.0553 mg, 0.015 mg/mL, 0.01 mg/pump actuation, 0.15 mg/pump actuation

Oral, , Tablet - Oral, Tablet, Nasal, Solution, Solution - Nasal, Solution - Intravenous, Intravenous, Injection, solution - Intravenous; Subcutaneous, Injection - Intravenous, Injection, Spray - Nasal, Intramuscular; Intravenous; Subcutaneous, Liquid - Intramuscular; Intravenous; Subcutaneous, Liquid, Spray, metered - Nasal, Spray, metered, Sublingual, Tablet, orally disintegrating - Sublingual, Tablet, orally disintegrating, Aerosol, metered - Nasal, Aerosol, metered, Tablet - Sublingual, Spray, Injection, solution, Injection - Intravenous; Subcutaneous, Solution - Intramuscular; Intravenous; Subcutaneous, Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous

Pituitary Surgery

0.1 mg, 0.2 mg, , 0.1 mg/mL, 0.004 mg/mL, 0.0001 mg/mL, 0.01 mg, 0.06 mg, 0.12 mg, 0.24 mg, 0.025 mg, 0.05 mg, 1.5 mg/mL, 0.00083 mg, 0.00166 mg, 0.0277 mg, 0.0553 mg, 0.015 mg/mL, 0.01 mg/pump actuation, 0.15 mg/pump actuation

Oral, , Tablet - Oral, Tablet, Nasal, Solution, Solution - Nasal, Solution - Intravenous, Intravenous, Injection, solution - Intravenous; Subcutaneous, Injection - Intravenous, Injection, Spray - Nasal, Intramuscular; Intravenous; Subcutaneous, Liquid - Intramuscular; Intravenous; Subcutaneous, Liquid, Spray, metered - Nasal, Spray, metered, Sublingual, Tablet, orally disintegrating - Sublingual, Tablet, orally disintegrating, Aerosol, metered - Nasal, Aerosol, metered, Tablet - Sublingual, Spray, Injection, solution, Injection - Intravenous; Subcutaneous, Solution - Intramuscular; Intravenous; Subcutaneous, Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous

Polyuria

0.1 mg, 0.2 mg, , 0.1 mg/mL, 0.004 mg/mL, 0.0001 mg/mL, 0.01 mg, 0.06 mg, 0.12 mg, 0.24 mg, 0.025 mg, 0.05 mg, 1.5 mg/mL, 0.00083 mg, 0.00166 mg, 0.0277 mg, 0.0553 mg, 0.015 mg/mL, 0.01 mg/pump actuation, 0.15 mg/pump actuation

Oral, , Tablet - Oral, Tablet, Nasal, Solution, Solution - Nasal, Solution - Intravenous, Intravenous, Injection, solution - Intravenous; Subcutaneous, Injection - Intravenous, Injection, Spray - Nasal, Intramuscular; Intravenous; Subcutaneous, Liquid - Intramuscular; Intravenous; Subcutaneous, Liquid, Spray, metered - Nasal, Spray, metered, Sublingual, Tablet, orally disintegrating - Sublingual, Tablet, orally disintegrating, Aerosol, metered - Nasal, Aerosol, metered, Tablet - Sublingual, Spray, Injection, solution, Injection - Intravenous; Subcutaneous, Solution - Intramuscular; Intravenous; Subcutaneous, Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous

Nocturnal Enuresis

0.1 mg, 0.2 mg, , 0.1 mg/mL, 0.004 mg/mL, 0.0001 mg/mL, 0.01 mg, 0.06 mg, 0.12 mg, 0.24 mg, 0.025 mg, 0.05 mg, 1.5 mg/mL, 0.00083 mg, 0.00166 mg, 0.0277 mg, 0.0553 mg, 0.015 mg/mL, 0.01 mg/pump actuation, 0.15 mg/pump actuation

Oral, , Tablet - Oral, Tablet, Nasal, Solution, Solution - Nasal, Solution - Intravenous, Intravenous, Injection, solution - Intravenous; Subcutaneous, Injection - Intravenous, Injection, Spray - Nasal, Intramuscular; Intravenous; Subcutaneous, Liquid - Intramuscular; Intravenous; Subcutaneous, Liquid, Spray, metered - Nasal, Spray, metered, Sublingual, Tablet, orally disintegrating - Sublingual, Tablet, orally disintegrating, Aerosol, metered - Nasal, Aerosol, metered, Tablet - Sublingual, Spray, Injection, solution, Injection - Intravenous; Subcutaneous, Solution - Intramuscular; Intravenous; Subcutaneous, Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous

Minor Surgical Procedures

0.1 mg, 0.2 mg, , 0.1 mg/mL, 0.004 mg/mL, 0.0001 mg/mL, 0.01 mg, 0.06 mg, 0.12 mg, 0.24 mg, 0.025 mg, 0.05 mg, 1.5 mg/mL, 0.00083 mg, 0.00166 mg, 0.0277 mg, 0.0553 mg, 0.015 mg/mL, 0.01 mg/pump actuation, 0.15 mg/pump actuation

Oral, , Tablet - Oral, Tablet, Nasal, Solution, Solution - Nasal, Solution - Intravenous, Intravenous, Injection, solution - Intravenous; Subcutaneous, Injection - Intravenous, Injection, Spray - Nasal, Intramuscular; Intravenous; Subcutaneous, Liquid - Intramuscular; Intravenous; Subcutaneous, Liquid, Spray, metered - Nasal, Spray, metered, Sublingual, Tablet, orally disintegrating - Sublingual, Tablet, orally disintegrating, Aerosol, metered - Nasal, Aerosol, metered, Tablet - Sublingual, Spray, Injection, solution, Injection - Intravenous; Subcutaneous, Solution - Intramuscular; Intravenous; Subcutaneous, Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous

Polyuria

0.1 mg, 0.2 mg, , 0.1 mg/mL, 0.004 mg/mL, 0.0001 mg/mL, 0.01 mg, 0.06 mg, 0.12 mg, 0.24 mg, 0.025 mg, 0.05 mg, 1.5 mg/mL, 0.00083 mg, 0.00166 mg, 0.0277 mg, 0.0553 mg, 0.015 mg/mL, 0.01 mg/pump actuation, 0.15 mg/pump actuation

Oral, , Tablet - Oral, Tablet, Nasal, Solution, Solution - Nasal, Solution - Intravenous, Intravenous, Injection, solution - Intravenous; Subcutaneous, Injection - Intravenous, Injection, Spray - Nasal, Intramuscular; Intravenous; Subcutaneous, Liquid - Intramuscular; Intravenous; Subcutaneous, Liquid, Spray, metered - Nasal, Spray, metered, Sublingual, Tablet, orally disintegrating - Sublingual, Tablet, orally disintegrating, Aerosol, metered - Nasal, Aerosol, metered, Tablet - Sublingual, Spray, Injection, solution, Injection - Intravenous; Subcutaneous, Solution - Intramuscular; Intravenous; Subcutaneous, Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous

Hemophilia A

0.1 mg, 0.2 mg, , 0.1 mg/mL, 0.004 mg/mL, 0.0001 mg/mL, 0.01 mg, 0.06 mg, 0.12 mg, 0.24 mg, 0.025 mg, 0.05 mg, 1.5 mg/mL, 0.00083 mg, 0.00166 mg, 0.0277 mg, 0.0553 mg, 0.015 mg/mL, 0.01 mg/pump actuation, 0.15 mg/pump actuation

Oral, , Tablet - Oral, Tablet, Nasal, Solution, Solution - Nasal, Solution - Intravenous, Intravenous, Injection, solution - Intravenous; Subcutaneous, Injection - Intravenous, Injection, Spray - Nasal, Intramuscular; Intravenous; Subcutaneous, Liquid - Intramuscular; Intravenous; Subcutaneous, Liquid, Spray, metered - Nasal, Spray, metered, Sublingual, Tablet, orally disintegrating - Sublingual, Tablet, orally disintegrating, Aerosol, metered - Nasal, Aerosol, metered, Tablet - Sublingual, Spray, Injection, solution, Injection - Intravenous; Subcutaneous, Solution - Intramuscular; Intravenous; Subcutaneous, Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous

Warnings

Nocdurna Contraindications

Condition

Risk Level

Notes

Hyponatremia

Do Not Combine

Renal Insufficiency

Do Not Combine

Hyponatremia

Do Not Combine

There are 20 known major drug interactions with Nocdurna.

Common Nocdurna Drug Interactions

Drug Name

Risk Level

Description

1-benzylimidazole

Minor

The risk or severity of hypertension can be increased when Desmopressin is combined with 1-benzylimidazole.

2,5-Dimethoxy-4-ethylamphetamine

Minor

The risk or severity of hypertension can be increased when Desmopressin is combined with 2,5-Dimethoxy-4-ethylamphetamine.

2,5-Dimethoxy-4-ethylthioamphetamine

Minor

The risk or severity of hypertension can be increased when Desmopressin is combined with 2,5-Dimethoxy-4-ethylthioamphetamine.

4-Bromo-2,5-dimethoxyamphetamine

Minor

The risk or severity of hypertension can be increased when Desmopressin is combined with 4-Bromo-2,5-dimethoxyamphetamine.

4-Methoxyamphetamine

Minor

The risk or severity of hypertension can be increased when Desmopressin is combined with 4-Methoxyamphetamine.

Nocdurna Toxicity & Overdose Risk

The lowest toxic dose of desmopressin in humans is 0.3 µg/kg/10M. Overdosing on desmopressin can lead to low levels of sodium in the blood, which can cause seizures, confusion, drowsiness, headaches, heart rhythm problems, and swelling. If an overdose occurs, the dose or frequency of the drug should be reduced or stopped. Checking the levels of sodium in the blood and seeking medical treatment is also recommended.

image of a doctor in a lab doing drug, clinical research

Nocdurna Novel Uses: Which Conditions Have a Clinical Trial Featuring Nocdurna?

Currently, 30 active trials are being conducted to assess the potential of Nocdurna in providing relief from Polyuria, Hemophilia A and Hemophilia B.

Condition

Clinical Trials

Trial Phases

Pituitary Diseases

0 Actively Recruiting

Hemorrhage

0 Actively Recruiting

Pituitary Surgery

0 Actively Recruiting

von Willebrand Disease

5 Actively Recruiting

Phase 3, Phase 1, Phase 2

Hemophilia A

3 Actively Recruiting

Phase 3, Phase 1

Uremia

0 Actively Recruiting

Nocturia

4 Actively Recruiting

Not Applicable, Phase 4

Polyuria

0 Actively Recruiting

Minor Surgical Procedures

0 Actively Recruiting

von Willebrand Disease

0 Actively Recruiting

Polydipsia

0 Actively Recruiting

Diabetes Insipidus, Neurogenic

2 Actively Recruiting

Phase 1, Early Phase 1

Hemophilia A

0 Actively Recruiting

Polyuria

0 Actively Recruiting

Hemorrhage

0 Actively Recruiting

Hemophilia A

0 Actively Recruiting

Nocturnal Enuresis

4 Actively Recruiting

Phase 3, Not Applicable

Nocdurna Reviews: What are patients saying about Nocdurna?

3

Patient Review

11/28/2021

Nocdurna for Urination During the Night

Nocdurna has helped me a lot. I used to wake up 12 times per night, and now it's more like 2-6.

2.7

Patient Review

10/31/2019

Nocdurna for Urination During the Night

1.7

Patient Review

8/5/2020

Nocdurna for Urination During the Night

Despite being able to afford the medication, it has not been effective in reducing my frequency. I'm very disappointed after 4 months of use.

1

Patient Review

9/8/2021

Nocdurna for Urination During the Night

Ineffective and did not provide any relief.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about nocdurna

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Nocdurna used for?

"NOCDURNA is used to help reduce the number of times you wake up at night to urinate due to nocturnal polyuria."

Answered by AI

How long does it take for Nocdurna to work?

"Antidiuretic hormone (ADH) helps the kidneys to produce less urine. NOCDURNA, on average, starts working within 30 minutes after you take it."

Answered by AI

Who manufactures Nocdurna?

"The FDA has approved NOCDURNA, the first sublingual tablet for the treatment of nocturia due to nocturnal polyuria in adults. NOCDURNA is taken before bedtime and dissolves under the tongue to help reduce the number of times you need to wake up at night to go to the bathroom."

Answered by AI

Is there a generic for Nocdurna?

"At this time, there are no drugs that are the same as Nocdurna, but not under the same name."

Answered by AI

Clinical Trials for Nocdurna

Have you considered Nocdurna clinical trials?

We made a collection of clinical trials featuring Nocdurna, we think they might fit your search criteria.
Go to Trials
Image of Children's Hospital Los Angeles in Los Angeles, United States.

Timed Awakening for Bedwetting

6 - 17
All Sexes
Los Angeles, CA

The goal of this clinical trial is to evaluate the effectiveness of nightly timed awakening in the treatment of nocturnal enuresis in children aged 6-17. The main questions it aims to: * Determine feasibility of nightly timed awakenings * Determine the role, if any, of comorbidities on resolution of enuresis * Determine incidence of daytime accidents * Obtain patient and parental satisfaction scores Researchers will compare a control group to treatment groups to see if there is any impact on nocturnal enuresis. Participants will be woken up by parents in the middle of the night to use the restroom. In addition, participants will receive 30 minute psychotherapy sessions using telehealth.

Waitlist Available
Has No Placebo

Children's Hospital Los Angeles

Evalynn Vasquez, MD

Image of Massachusetts General Hospital in Boston, United States.

Norethindrone Acetate-Ethinyl Estradiol for Oxytocin Deficiency

18 - 65
All Sexes
Boston, MA

This is an open-label, pilot study, to characterize oxytocin response to a single dose of oral Estrogen-progestin in patients with arginine-vasopressin deficiency compared to healthy controls. The association between oxytocin levels and measures of psychopathology (i.e., anxiety and depression) and quality of life across groups will be examined. We hypothesize that: 1. Salivary and blood oxytocin response to Estrogen-progestin will be lower in arginine-vasopressin deficiency compared to healthy control. 2. Lower salivary and blood oxytocin levels will be associated with more severe symptoms of anxiety, depression, and social emotional difficulties as well as lower quality of life.

Phase < 1
Recruiting

Massachusetts General Hospital

Elizabeth A Lawson, MD

Image of Albany Medical College in Albany, United States.

TENS for Bedwetting

5 - 17
All Sexes
Albany, NY

Children referred to pediatric urology clinic for primary nocturnal enuresis will be screened for enrollment. Patients who fail will next be offered therapy with a bedwetting alarm device or a TENS unit as an alternative, and those who chose TENS therapy will be included in the study.The patients will be randomized into two groups of 35 patients each.Group 1 will be the high pulse width set at 260us. Group 2 will be the low pulse width set at 50us. The patients will be provided with a TENS unit and electrode pads and caretakers instructed on how to use the apparatus. The child's TENS unit will be set at a pulse width determined by randomization, frequency of 10Hz, and an intensity to be determined in the office based upon when the child feels sensitive to the TENS unit. The child will be randomized and will place the electrodes along the posterior tibial nerve on the medial ankle each night before bed time for 30 minutes for a total of 30 days. Diaries including nighttime incontinence episodes and a "wet sheet" scale (dry, damp, wet, soaked) will be recorded, along with any adverse reactions to the TENS unit. Patients will be followed up after one month of TENS with evaluation including the Bowel \& Bladder Questionnaire (BBQ), a validated tool for measuring symptoms in children with voiding dysfunction \[6\]; this questionnaire will be filled out prior to starting TENS treatment in order to compare the effect of treatment. The data will be collected at different time points (baseline and after 1 month of treatment) for each group by itself and the groups compared against each other using statistical analysis.

Recruiting
Has No Placebo

Albany Medical College

Adam Howe, MD

Have you considered Nocdurna clinical trials?

We made a collection of clinical trials featuring Nocdurna, we think they might fit your search criteria.
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Have you considered Nocdurna clinical trials?

We made a collection of clinical trials featuring Nocdurna, we think they might fit your search criteria.
Go to Trials