Neptazane
Open Angle Glaucoma
Treatment
3 FDA approvals
9 Active Studies for Neptazane
Treatment for
Open Angle Glaucoma
What is Neptazane
Methazolamide
The Generic name of this drug
Treatment Summary
Acetazolamide is a medication used to reduce fluid buildup in the body and treat glaucoma. It works by blocking an enzyme called carbonic anhydrase, which helps the body produce fluids. Acetazolamide is a type of diuretic, which means it helps the body get rid of excess fluid.
Methazolamide
is the brand name
Neptazane Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Methazolamide
Methazolamide
1993
34
Approved as Treatment by the FDA
Methazolamide, also known as Methazolamide, is approved by the FDA for 3 uses which include Open Angle Glaucoma (OAG) and Acute angle-closure glaucoma .
Open Angle Glaucoma (OAG)
Helps manage Open Angle Glaucoma (OAG)
Acute angle-closure glaucoma
Open Angle Glaucoma
Helps manage Open Angle Glaucoma (OAG)
Effectiveness
How Neptazane Affects Patients
Methazolamide is a drug used to lower pressure in the eyes of people with glaucoma or ocular hypertension who don't respond well to beta-blockers. It is a sulfonamide derivative, but does not have any strong antimicrobial properties. It is not used as an anticonvulsant and only has a small, short-term diuretic effect, resulting in more urine being produced with higher amounts of sodium, potassium, and chloride.
How Neptazane works in the body
Methazolamide works by slowing down the production of bicarbonate ions in the eyes. This reduces the amount of sodium and fluid in the eye, leading to decreased aqueous humor secretion.
When to interrupt dosage
The proposed measure of Neptazane is contingent upon the diagnosed condition. The quantity of dosage fluctuates, as per the technique of delivery (e.g. Oral or Tablet) featured in the table beneath.
Condition
Dosage
Administration
Open Angle Glaucoma
, 50.0 mg, 25.0 mg
, Tablet - Oral, Tablet, Oral
Warnings
Neptazane has nine contraindications, so it should not be employed when having any of the ailments enumerated in the following table.
Neptazane Contraindications
Condition
Risk Level
Notes
Cirrhosis
Do Not Combine
Adrenal Insufficiency
Do Not Combine
Hyponatremia
Do Not Combine
Glaucoma, Angle-Closure
Do Not Combine
hyperchloremic acidosis
Do Not Combine
Abnormal Renal Function
Do Not Combine
Hypokalemia
Do Not Combine
Pulse Frequency
Do Not Combine
Liver Dysfunction
Do Not Combine
There are 20 known major drug interactions with Neptazane.
Common Neptazane Drug Interactions
Drug Name
Risk Level
Description
Acetazolamide
Major
The risk or severity of adverse effects can be increased when Methazolamide is combined with Acetazolamide.
Cyclopentamine
Major
The risk or severity of adverse effects can be increased when Methazolamide is combined with Cyclopentamine.
Diclofenamide
Major
The risk or severity of adverse effects can be increased when Methazolamide is combined with Diclofenamide.
Dorzolamide
Major
The risk or severity of adverse effects can be increased when Methazolamide is combined with Dorzolamide.
Hexamethonium
Major
The risk or severity of adverse effects can be increased when Methazolamide is combined with Hexamethonium.
Neptazane Toxicity & Overdose Risk
An overdose on electrolytes can lead to an imbalance of these minerals in the body, an acidic environment, and effects on the central nervous system.
Neptazane Novel Uses: Which Conditions Have a Clinical Trial Featuring Neptazane?
12 active trials are being conducted to examine the potential of Neptazane in alleviating Glaucoma.
Condition
Clinical Trials
Trial Phases
Open Angle Glaucoma
10 Actively Recruiting
Phase 3, Not Applicable, Phase 4
Neptazane Reviews: What are patients saying about Neptazane?
4
Patient Review
3/6/2009
Neptazane for High Eye Pressure or Glaucoma that May Worsen without Treatment
Patient Q&A Section about neptazane
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
What is the difference between methazolamide and acetazolamide?
"Acetazolamide, which inhibits carbonic anhydrase, is recommended as a prophylactic against AMS, but may cause side effects such as tingling. Methazolamide has the same pharmacological effect, but diffuses more quickly into tissue and is more potent than acetazolamide."
Answered by AI
Does methazolamide lower blood pressure?
"Although the pressure-lowering effects of methazolamide begin after two to four hours, it is unclear if people with glaucoma should continue using their current eye drops. Some people might require multiple medications to appropriately treat their glaucoma."
Answered by AI
What is Neptazane used for?
"This medication works by decreasing the amount of fluid in the eye, which lowers pressure inside the eye."
Answered by AI
What does methazolamide do to the body?
"Methazolamide reduces the activity of the carbonic anhydrase protein in your body. Blocking this protein can help reduce the amount of fluid in the eye and lower pressure inside the eye. Methazolamide is used to treat glaucoma by lowering intraocular pressure."
Answered by AI