Neptazane

Open Angle Glaucoma

Treatment

3 FDA approvals

12 Active Studies for Neptazane

Treatment for

Open Angle Glaucoma

What is Neptazane

MethazolamideThe Generic name of this drug

Treatment SummaryAcetazolamide is a medication used to reduce fluid buildup in the body and treat glaucoma. It works by blocking an enzyme called carbonic anhydrase, which helps the body produce fluids. Acetazolamide is a type of diuretic, which means it helps the body get rid of excess fluid.

Methazolamideis the brand name

image of different drug pills on a surface

Neptazane Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Methazolamide

1993

Approved as Treatment by the FDA

Methazolamide, also known as Methazolamide, is approved by the FDA for 3 uses which include Acute angle-closure glaucoma and Open Angle Glaucoma (OAG) .

Acute angle-closure glaucoma

Open Angle Glaucoma (OAG)

Helps manage Open Angle Glaucoma (OAG)

Open Angle Glaucoma

Helps manage Open Angle Glaucoma (OAG)

Effectiveness

How Neptazane Affects PatientsMethazolamide is a drug used to lower pressure in the eyes of people with glaucoma or ocular hypertension who don't respond well to beta-blockers. It is a sulfonamide derivative, but does not have any strong antimicrobial properties. It is not used as an anticonvulsant and only has a small, short-term diuretic effect, resulting in more urine being produced with higher amounts of sodium, potassium, and chloride.

How Neptazane works in the bodyMethazolamide works by slowing down the production of bicarbonate ions in the eyes. This reduces the amount of sodium and fluid in the eye, leading to decreased aqueous humor secretion.

When to interrupt dosage

The proposed measure of Neptazane is contingent upon the diagnosed condition. The quantity of dosage fluctuates, as per the technique of delivery (e.g. Oral or Tablet) featured in the table beneath.

Condition

Dosage

Administration

Open Angle Glaucoma

, 50.0 mg, 25.0 mg

, Oral, Tablet, Tablet - Oral

Warnings

Neptazane has nine contraindications, so it should not be employed when having any of the ailments enumerated in the following table.Neptazane Contraindications

Condition

Risk Level

Notes

Cirrhosis

Do Not Combine

Adrenal Insufficiency

Do Not Combine

Hyponatremia

Do Not Combine

Glaucoma, Angle-Closure

Do Not Combine

hyperchloremic acidosis

Do Not Combine

Abnormal Renal Function

Do Not Combine

Hypokalemia

Do Not Combine

Pulse Frequency

Do Not Combine

Liver Dysfunction

Do Not Combine

There are 20 known major drug interactions with Neptazane.

Common Neptazane Drug Interactions

Drug Name

Risk Level

Description

Acetazolamide

Major

The risk or severity of adverse effects can be increased when Methazolamide is combined with Acetazolamide.

Cyclopentamine

Major

The risk or severity of adverse effects can be increased when Methazolamide is combined with Cyclopentamine.

Diclofenamide

Major

The risk or severity of adverse effects can be increased when Methazolamide is combined with Diclofenamide.

Dorzolamide

Major

The risk or severity of adverse effects can be increased when Methazolamide is combined with Dorzolamide.

Hexamethonium

Major

The risk or severity of adverse effects can be increased when Methazolamide is combined with Hexamethonium.

Neptazane Toxicity & Overdose RiskAn overdose on electrolytes can lead to an imbalance of these minerals in the body, an acidic environment, and effects on the central nervous system.

image of a doctor in a lab doing drug, clinical research

Neptazane Novel Uses: Which Conditions Have a Clinical Trial Featuring Neptazane?

12 active trials are being conducted to examine the potential of Neptazane in alleviating Glaucoma.

Condition

Clinical Trials

Trial Phases

Open Angle Glaucoma

12 Actively Recruiting

Phase 3, Not Applicable, Phase 2, Phase 4, Phase 1

Neptazane Reviews: What are patients saying about Neptazane?

4Patient Review

3/6/2009

Neptazane for High Eye Pressure or Glaucoma that May Worsen without Treatment

Patient Q&A Section about neptazane

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the difference between methazolamide and acetazolamide?

"Acetazolamide, which inhibits carbonic anhydrase, is recommended as a prophylactic against AMS, but may cause side effects such as tingling. Methazolamide has the same pharmacological effect, but diffuses more quickly into tissue and is more potent than acetazolamide."

Answered by AI

Does methazolamide lower blood pressure?

"Although the pressure-lowering effects of methazolamide begin after two to four hours, it is unclear if people with glaucoma should continue using their current eye drops. Some people might require multiple medications to appropriately treat their glaucoma."

Answered by AI

What is Neptazane used for?

"This medication works by decreasing the amount of fluid in the eye, which lowers pressure inside the eye."

Answered by AI

What does methazolamide do to the body?

"Methazolamide reduces the activity of the carbonic anhydrase protein in your body. Blocking this protein can help reduce the amount of fluid in the eye and lower pressure inside the eye. Methazolamide is used to treat glaucoma by lowering intraocular pressure."

Answered by AI

Clinical Trials for Neptazane

Have you considered Neptazane clinical trials? We made a collection of clinical trials featuring Neptazane, we think they might fit your search criteria.

Have you considered Neptazane clinical trials? We made a collection of clinical trials featuring Neptazane, we think they might fit your search criteria.