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What is Morphabond Er
MorphineThe Generic name of this drug
Treatment SummaryMorphine is a strong pain reliever, first extracted from poppy plants in 1805. It is still used today to treat severe pain, however other medications such as codeine, fentanyl, methadone, hydrocodone, hydromorphone, meperidine, and oxycodone are often used as alternatives due to the risks associated with morphine use (tolerance, withdrawal, and abuse). Morphine was officially approved by the FDA in 1941.
Morphine Sulfateis the brand name
Morphabond Er Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Morphine Sulfate
Morphine
1971
459
Approved as Treatment by the FDA
Morphine, also known as Morphine Sulfate, is approved by the FDA for 2 uses including Chronic Pain and Pain .Chronic Pain
Helps manage Pain, Chronic
Pain
Effectiveness
How Morphabond Er Affects PatientsMorphine blocks pain signals from reaching the brain, which helps reduce pain. Its effects can take anywhere from 6-30 minutes to kick in. Taking too much morphine and other opioids can cause permanent changes in the brain. Morphine works differently in men and women, with women needing less of it to feel the same effects. Morphine-6-glucuronide is much weaker than morphine when it comes to constricting the pupils.
How Morphabond Er works in the bodyMorphine-6-glucuronide is the primary chemical responsible for the effects of morphine. It binds to two types of opioid receptors: mu and kappa. The mu-opioid receptor is responsible for morphine's effects on the brain's reward system, breathing, and addiction. The kappa-opioid receptor helps with pain relief.
When to interrupt dosage
The suggested dosage of Morphabond Er is founded on the diagnosed condition, including Therapeutic procedure, Pain and Chronic Pain. The amount additionally alters as per the method of delivery exemplified in the table below.Condition
Dosage
Administration
Chronic Pain
10.0 mg/mL, , 20.0 mg, 50.0 mg, 60.0 mg, 30.0 mg, 10.0 mg, 80.0 mg, 100.0 mg, 200.0 mg, 0.5 mg/mL, 1.0 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 3.0 mg/mL, 100.0 mg/mL, 5.0 mg, 15.0 mg, 20.0 mg/mL, 15.0 mg/mL, 5.0 mg/mL, 8.0 mg/mL, 4.0 mg/mL, 90.0 mg, 120.0 mg, 40.0 mg, 70.0 mg, 130.0 mg, 150.0 mg, 2.0 mg/mL, 45.0 mg, 75.0 mg, 25.0 mg, 40.0 mg/mL, 1.1 mg/mL, 0.1 mg/mL
, Oral, Solution, Solution - Oral, Capsule, extended release - Oral, Capsule, extended release, Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Injection, solution - Epidural; Intrathecal; Intravenous, Epidural; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intravenous, Intravenous; Subcutaneous, Injection, solution - Intravenous; Subcutaneous, Rectal, Suppository, Suppository - Rectal, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Intramuscular; Intravenous; Subcutaneous, Injection, Injection - Intramuscular; Intravenous; Subcutaneous, Injection - Intravenous, Capsule, coated, extended release, Capsule, coated, extended release - Oral, Tablet - Oral, Tablet, Tablet, extended release, Tablet, extended release - Oral, Intrathecal; Intravenous, Injection, solution - Intrathecal; Intravenous, Epidural; Intramuscular; Intrathecal; Intravenous, Injection, solution - Epidural; Intramuscular; Intrathecal; Intravenous, Capsule, Capsule - Oral, Solution / drops, Solution / drops - Oral, Solution - Intramuscular; Intravenous; Subcutaneous, Epidural, Solution - Epidural, Solution - Intravenous; Subcutaneous, Epidural; Intravenous; Subcutaneous, Solution - Epidural; Intravenous; Subcutaneous, Liquid, Liquid - Intramuscular; Intravenous; Subcutaneous, Liquid - Intravenous; Subcutaneous, Syrup - Oral, Syrup, Solution - Intravenous, Liquid - Intravenous, Tincture, Tincture - Oral, Suppository, extended release, Suppository, extended release - Rectal, Intramuscular, Injection - Intramuscular, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Injection - Epidural; Intrathecal; Intravenous, Epidural; Intrathecal, Injection, solution - Epidural; Intrathecal, Solution, concentrate, Solution, concentrate - Oral, Liquid - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Parenteral, Solution - Parenteral, Tablet, film coated, Tablet, film coated - Oral, Injection, lipid complex - Epidural, Injection, lipid complex, Injection - Parenteral, Intrathecal, Injection, solution - Intrathecal, Injection - Epidural; Intrathecal, Injection, solution - Epidural; Intraspinal; Intrathecal; Intravenous; Subarachnoid, Epidural; Intraspinal; Intrathecal; Intravenous; Subarachnoid
Pain
10.0 mg/mL, , 20.0 mg, 50.0 mg, 60.0 mg, 30.0 mg, 10.0 mg, 80.0 mg, 100.0 mg, 200.0 mg, 0.5 mg/mL, 1.0 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 3.0 mg/mL, 100.0 mg/mL, 5.0 mg, 15.0 mg, 20.0 mg/mL, 15.0 mg/mL, 5.0 mg/mL, 8.0 mg/mL, 4.0 mg/mL, 90.0 mg, 120.0 mg, 40.0 mg, 70.0 mg, 130.0 mg, 150.0 mg, 2.0 mg/mL, 45.0 mg, 75.0 mg, 25.0 mg, 40.0 mg/mL, 1.1 mg/mL, 0.1 mg/mL
, Oral, Solution, Solution - Oral, Capsule, extended release - Oral, Capsule, extended release, Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Injection, solution - Epidural; Intrathecal; Intravenous, Epidural; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intravenous, Intravenous; Subcutaneous, Injection, solution - Intravenous; Subcutaneous, Rectal, Suppository, Suppository - Rectal, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Intramuscular; Intravenous; Subcutaneous, Injection, Injection - Intramuscular; Intravenous; Subcutaneous, Injection - Intravenous, Capsule, coated, extended release, Capsule, coated, extended release - Oral, Tablet - Oral, Tablet, Tablet, extended release, Tablet, extended release - Oral, Intrathecal; Intravenous, Injection, solution - Intrathecal; Intravenous, Epidural; Intramuscular; Intrathecal; Intravenous, Injection, solution - Epidural; Intramuscular; Intrathecal; Intravenous, Capsule, Capsule - Oral, Solution / drops, Solution / drops - Oral, Solution - Intramuscular; Intravenous; Subcutaneous, Epidural, Solution - Epidural, Solution - Intravenous; Subcutaneous, Epidural; Intravenous; Subcutaneous, Solution - Epidural; Intravenous; Subcutaneous, Liquid, Liquid - Intramuscular; Intravenous; Subcutaneous, Liquid - Intravenous; Subcutaneous, Syrup - Oral, Syrup, Solution - Intravenous, Liquid - Intravenous, Tincture, Tincture - Oral, Suppository, extended release, Suppository, extended release - Rectal, Intramuscular, Injection - Intramuscular, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Injection - Epidural; Intrathecal; Intravenous, Epidural; Intrathecal, Injection, solution - Epidural; Intrathecal, Solution, concentrate, Solution, concentrate - Oral, Liquid - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Parenteral, Solution - Parenteral, Tablet, film coated, Tablet, film coated - Oral, Injection, lipid complex - Epidural, Injection, lipid complex, Injection - Parenteral, Intrathecal, Injection, solution - Intrathecal, Injection - Epidural; Intrathecal, Injection, solution - Epidural; Intraspinal; Intrathecal; Intravenous; Subarachnoid, Epidural; Intraspinal; Intrathecal; Intravenous; Subarachnoid
Therapeutic procedure
10.0 mg/mL, , 20.0 mg, 50.0 mg, 60.0 mg, 30.0 mg, 10.0 mg, 80.0 mg, 100.0 mg, 200.0 mg, 0.5 mg/mL, 1.0 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 3.0 mg/mL, 100.0 mg/mL, 5.0 mg, 15.0 mg, 20.0 mg/mL, 15.0 mg/mL, 5.0 mg/mL, 8.0 mg/mL, 4.0 mg/mL, 90.0 mg, 120.0 mg, 40.0 mg, 70.0 mg, 130.0 mg, 150.0 mg, 2.0 mg/mL, 45.0 mg, 75.0 mg, 25.0 mg, 40.0 mg/mL, 1.1 mg/mL, 0.1 mg/mL
, Oral, Solution, Solution - Oral, Capsule, extended release - Oral, Capsule, extended release, Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Injection, solution - Epidural; Intrathecal; Intravenous, Epidural; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intravenous, Intravenous; Subcutaneous, Injection, solution - Intravenous; Subcutaneous, Rectal, Suppository, Suppository - Rectal, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Intramuscular; Intravenous; Subcutaneous, Injection, Injection - Intramuscular; Intravenous; Subcutaneous, Injection - Intravenous, Capsule, coated, extended release, Capsule, coated, extended release - Oral, Tablet - Oral, Tablet, Tablet, extended release, Tablet, extended release - Oral, Intrathecal; Intravenous, Injection, solution - Intrathecal; Intravenous, Epidural; Intramuscular; Intrathecal; Intravenous, Injection, solution - Epidural; Intramuscular; Intrathecal; Intravenous, Capsule, Capsule - Oral, Solution / drops, Solution / drops - Oral, Solution - Intramuscular; Intravenous; Subcutaneous, Epidural, Solution - Epidural, Solution - Intravenous; Subcutaneous, Epidural; Intravenous; Subcutaneous, Solution - Epidural; Intravenous; Subcutaneous, Liquid, Liquid - Intramuscular; Intravenous; Subcutaneous, Liquid - Intravenous; Subcutaneous, Syrup - Oral, Syrup, Solution - Intravenous, Liquid - Intravenous, Tincture, Tincture - Oral, Suppository, extended release, Suppository, extended release - Rectal, Intramuscular, Injection - Intramuscular, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Injection - Epidural; Intrathecal; Intravenous, Epidural; Intrathecal, Injection, solution - Epidural; Intrathecal, Solution, concentrate, Solution, concentrate - Oral, Liquid - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Parenteral, Solution - Parenteral, Tablet, film coated, Tablet, film coated - Oral, Injection, lipid complex - Epidural, Injection, lipid complex, Injection - Parenteral, Intrathecal, Injection, solution - Intrathecal, Injection - Epidural; Intrathecal, Injection, solution - Epidural; Intraspinal; Intrathecal; Intravenous; Subarachnoid, Epidural; Intraspinal; Intrathecal; Intravenous; Subarachnoid
Warnings
Morphabond Er has six contraindications, so it must not be simultaneously taken with any of the conditions in the table below.Morphabond Er ContraindicationsCondition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Mental Depression
Do Not Combine
Asthma
Do Not Combine
Gastrointestinal obstruction
Do Not Combine
Pulse Frequency
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Morphine may interact with Pulse Frequency
Common Morphabond Er Drug Interactions
Drug Name
Risk Level
Description
Azelastine
Major
Morphine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Brigatinib
Major
The metabolism of Brigatinib can be decreased when combined with Morphine.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Morphine.
Eluxadoline
Major
The risk or severity of constipation can be increased when Morphine is combined with Eluxadoline.
Enasidenib
Major
The metabolism of Enasidenib can be decreased when combined with Morphine.
Morphabond Er Toxicity & Overdose RiskThe toxic dose of this drug is 0.78 micrograms per milliliter for males and 0.98 micrograms per milliliter for females. An overdose can cause difficulty breathing, drowsiness, limp muscles, cold and clammy skin, constricted pupils, and dilated pupils. Severe symptoms may include fluid buildup in the lungs, slow heartbeat, low blood pressure, heart failure, and even death. Treatment of an overdose involves providing oxygen, medications to raise blood pressure, and a medicine called naloxone.
Morphabond Er Novel Uses: Which Conditions Have a Clinical Trial Featuring Morphabond Er?
24 active clinical trials are currently being conducted to assess the potential of Morphabond Er in providing therapeutic intervention, alleviating Pain and ameliorating Chronic Pain.Condition
Clinical Trials
Trial Phases
Chronic Pain
31 Actively Recruiting
Phase 2, Not Applicable, Phase 3
Therapeutic procedure
0 Actively Recruiting
Pain
0 Actively Recruiting
Morphabond Er Reviews: What are patients saying about Morphabond Er?
4.3Patient Review
11/20/2018 Though I follow the prescribed dosage, these pills do nothing for me in terms of relief. All they do is make me feel like I'm sweating all the time.
2.3Patient Review
9/10/2019 I was pretty disappointed with this treatment. It didn't work nearly as well as my usual, generic brand. I think it releases too slowly over too long of a time compared to the other. I now constantly feel pain and need more medication.
Patient Q&A Section about morphabond er
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Can MS Contin 15 mg ER be crushed?
"You should swallow MS Contin tablets whole, and not break, chew, dissolve or crush them."
Answered by AI
Can you crush morphine sulfate immediate release?
"Take morphine sulfate extended-release tablets as a whole. Do not cut, break, chew, crush, dissolve, snort, or inject morphine sulfate extended-release tablets as this can lead to an overdose and death."
Answered by AI
What is MST analgesic?
"MST Continus is a medication used to relieve severe pain over a period of 12 hours. It contains the active ingredient morphine which belongs to a group of medicines called strong analgesics or 'painkillers'."
Answered by AI
What is Morphabond used for?
"Morphabond is a Morphine Sulfate that is used to treat the symptoms of Acute Pain and Chronic Severe Pain. It may be used alone or with other medications."
Answered by AI