Micronase

Glycemic Control, Type 2 Diabetes, Gestational Diabetes Mellitus
Treatment
3 FDA approvals
20 Active Studies for Micronase

What is Micronase

GlyburideThe Generic name of this drug
Treatment SummaryGlyburide is a medication used to treat type 2 diabetes. It is usually given to patients who cannot control their diabetes with metformin, the standard first-line therapy. Glyburide works by stimulating insulin production by closing off potassium channels on the beta cells, which increases the amount of potassium and calcium in the cells. Glyburide was approved by the FDA in 1984 and a combination formulation with metformin was approved in 2000.
Micronaseis the brand name
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Micronase Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Micronase
Glyburide
1984
341

Approved as Treatment by the FDA

Glyburide, also known as Micronase, is approved by the FDA for 3 uses which include Type 2 Diabetes Mellitus and Type 2 Diabetes .
Type 2 Diabetes Mellitus
Helps manage Type 2 Diabetes Mellitus
Type 2 Diabetes
Helps manage Type 2 Diabetes Mellitus
Glycemic Control
Used to treat Glycemic Control in combination with Metformin

Effectiveness

How Micronase Affects PatientsGlyburide is a medication that helps the body produce more insulin. It usually needs to be taken just once per day and is usually started at a low dose (0.75mg) but can be increased to 10mg or more. However, taking glyburide may increase the risk of cardiovascular death, just like with another type of medicine called tolbutamide.
How Micronase works in the bodyGlyburide is a medication used to help with diabetes. It belongs to a class of drugs called sulfonylureas. These drugs work by blocking a special kind of potassium channel that is found in the pancreas. Normally, these channels open and close in response to glucose levels in the body, which helps to regulate insulin production. Glyburide forces these channels to stay closed, which increases the amount of insulin produced.

When to interrupt dosage

The recommended measure of Micronase is contingent upon the determined condition, including Glycemic Control, Type 2 Diabetes and Gestational Diabetes. The quantity of dosage is delineated in the following table, relying on the technique of administration (e.g. Oral or Tablet).
Condition
Dosage
Administration
Type 2 Diabetes
, 1.25 mg, 2.5 mg, 1.5 mg, 3.0 mg, 6.0 mg, 5.0 mg, 6.0 mg/mL, 0.6 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral
Gestational Diabetes Mellitus
, 1.25 mg, 2.5 mg, 1.5 mg, 3.0 mg, 6.0 mg, 5.0 mg, 6.0 mg/mL, 0.6 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral
Glycemic Control
, 1.25 mg, 2.5 mg, 1.5 mg, 3.0 mg, 6.0 mg, 5.0 mg, 6.0 mg/mL, 0.6 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral

Warnings

Micronase has six contraindications. It should not be consumed while encountering any of the conditions set forth in the following table.Micronase Contraindications
Condition
Risk Level
Notes
Type 1 Diabetes
Do Not Combine
Acidosis
Do Not Combine
Comatose
Do Not Combine
Diabetic Ketoacidosis
Do Not Combine
Pulse Frequency
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Glyburide may interact with Pulse Frequency
There are 20 known major drug interactions with Micronase.
Common Micronase Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The metabolism of Abemaciclib can be decreased when combined with Glyburide.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be decreased when combined with Glyburide.
Alectinib
Major
The metabolism of Alectinib can be decreased when combined with Glyburide.
Aminophylline
Major
The metabolism of Aminophylline can be decreased when combined with Glyburide.
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Glyburide.
Micronase Toxicity & Overdose RiskThe lowest toxic dose of the drug in rats is greater than 3200mg/kg, in mice is greater than 1500mg/kg, in rabbits is greater than 10,000mg/kg, and in guinea pigs is greater than 1500mg/kg. Those who overdose may experience low blood sugar levels. Mild cases can be treated by consuming glucose and adjusting doses or meal times. Severe cases require hospitalization with an IV of glucose and monitoring for up to two days.
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Micronase Novel Uses: Which Conditions Have a Clinical Trial Featuring Micronase?

Currently, there are 196 active trials looking into the potential of Micronase to provide Gestational Diabetes, Glycemic Control and Type 2 Diabetes management.
Condition
Clinical Trials
Trial Phases
Type 2 Diabetes
174 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3, Phase 4, Early Phase 1
Gestational Diabetes Mellitus
33 Actively Recruiting
Not Applicable, Phase 4, Phase 2, Phase 3, Early Phase 1
Glycemic Control
2 Actively Recruiting
Not Applicable

Micronase Reviews: What are patients saying about Micronase?

5Patient Review
2/18/2009
Micronase for Type 2 Diabetes Mellitus
I've only been using this medication for three weeks, but the results were immediate and great! The only downside is that I have to eat a mid-morning snack to prevent low blood sugar, but that's not really a big deal.
4.7Patient Review
8/24/2009
Micronase for Type 2 Diabetes Mellitus
This has been an effective treatment for me.
4.7Patient Review
10/29/2008
Micronase for Type 2 Diabetes Mellitus
I lost a perfectly healthy baby due to my doctor's negligence in monitoring my liver and kidney function. They recklessly increased my dosage from 1.25 pills to 6 pills in 2 weeks.
4Patient Review
2/13/2008
Micronase for Type 2 Diabetes Mellitus
3Patient Review
5/28/2010
Micronase for Type 2 Diabetes Mellitus
I've been taking Metformin with Glyburid for a few years now, and it hasn't done much to lower my blood sugar. Recently, my doctor discovered that I have a liver problem. This is concerning because last year my liver was healthy.
View All Reviews
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Patient Q&A Section about micronase

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the most common side effect of glyburide?

"Glyburide can cause side effects such as diarrhea, dizziness, and headache."

Answered by AI

What are the most common adverse effects of glyburide Micronase )?

"You may experience low blood sugar, nausea, heartburn, feeling full, muscle or joint pain, blurred vision, or a mild rash or skin redness."

Answered by AI

What is Micronase used for?

"Glyburide is a medication used to control high blood sugar in people with type 2 diabetes. It is typically used in conjunction with a proper diet and exercise program. Controlling high blood sugar helps prevent a variety of issues including kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems."

Answered by AI

Is Micronase the same as glyburide?

"The drug Micronase, which is used to lower blood sugar, contains the compound glyburide. Glyburide is a white, crystalline substance that is available in tablets of 1.25, 2.5, and 5 mg strengths."

Answered by AI

Clinical Trials for Micronase

Have you considered Micronase clinical trials? We made a collection of clinical trials featuring Micronase, we think they might fit your search criteria.
Have you considered Micronase clinical trials? We made a collection of clinical trials featuring Micronase, we think they might fit your search criteria.
Have you considered Micronase clinical trials? We made a collection of clinical trials featuring Micronase, we think they might fit your search criteria.
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