Mellaril

Schizophrenia, Schizophrenia, Alzheimer's Disease
Treatment
1 FDA approval
20 Active Studies for Mellaril

What is Mellaril

ThioridazineThe Generic name of this drug
Treatment SummaryThioridazine is a type of antipsychotic medication used to treat schizophrenia and agitation. It does not have the same anti-nausea effects as other similar medications, but it has a lower risk of causing side effects like muscle stiffness. Thioridazine was taken off the market in 2005 due to its association with heart rhythm problems.
Thioridazine Hydrochlorideis the brand name
image of different drug pills on a surface
Mellaril Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Thioridazine Hydrochloride
Thioridazine
1983
20

Approved as Treatment by the FDA

Thioridazine, otherwise known as Thioridazine Hydrochloride, is approved by the FDA for 1 uses like Schizophrenia .
Schizophrenia
Helps manage Schizophrenia

Effectiveness

How Mellaril Affects PatientsThioridazine is a drug used to treat schizophrenia and other mental health disorders. It has not been found to be helpful in managing behavioral issues in people with intellectual disabilities.
How Mellaril works in the bodyThioridazine works by blocking two types of dopamine receptors in the brain. It also reduces the effects of certain hormones released by the hypothalamus and pituitary gland, and suppresses activity in the parts of the brain that control metabolism, body temperature, alertness and vomiting.

When to interrupt dosage

The advised dose of Mellaril is contingent upon the diagnosed condition, like Schizophrenia, Alzheimer's Disease and Schizophrenia. The measure of dosage fluctuates as per the method of administration depicted in the table below.
Condition
Dosage
Administration
Schizophrenia
, 25.0 mg, 50.0 mg, 10.0 mg, 100.0 mg, 200.0 mg, 30.0 mg/mL, 10.0 mg/mL, 5.0 mg/mL, 2.0 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Suspension, Suspension - Oral, Liquid - Oral, Liquid, Solution, Solution - Oral
Alzheimer's Disease
, 25.0 mg, 50.0 mg, 10.0 mg, 100.0 mg, 200.0 mg, 30.0 mg/mL, 10.0 mg/mL, 5.0 mg/mL, 2.0 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Suspension, Suspension - Oral, Liquid - Oral, Liquid, Solution, Solution - Oral
Schizophrenia
, 25.0 mg, 50.0 mg, 10.0 mg, 100.0 mg, 200.0 mg, 30.0 mg/mL, 10.0 mg/mL, 5.0 mg/mL, 2.0 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Suspension, Suspension - Oral, Liquid - Oral, Liquid, Solution, Solution - Oral

Warnings

Mellaril Contraindications
Condition
Risk Level
Notes
Comatose
Do Not Combine
Hypotension
Do Not Combine
Pulse Frequency
Do Not Combine
extremely hypertensive heart disease
Do Not Combine
Mental Depression
Do Not Combine
Long QT Syndrome
Do Not Combine
Pulse Frequency
Do Not Combine
Cardiac Arrhythmia
Do Not Combine
Cytochrome P450
Do Not Combine
There are 20 known major drug interactions with Mellaril.
Common Mellaril Drug Interactions
Drug Name
Risk Level
Description
4-Methoxyamphetamine
Major
The metabolism of 4-Methoxyamphetamine can be decreased when combined with Thioridazine.
5-methoxy-N,N-dimethyltryptamine
Major
The metabolism of 5-methoxy-N,N-dimethyltryptamine can be decreased when combined with Thioridazine.
Acebutolol
Major
The metabolism of Acebutolol can be decreased when combined with Thioridazine.
Acepromazine
Major
Thioridazine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Acepromazine.
Alfuzosin
Major
Thioridazine may increase the hypotensive activities of Alfuzosin.
Mellaril Toxicity & Overdose RiskThe lowest toxic dose of the drug in rats is between 956-1034mg/kg when taken orally. Overdosing can cause symptoms such as agitation, blurred vision, confusion, constipation, difficulty breathing, dilated or constricted pupils, dry mouth and skin, low body temperature, low blood pressure, fluid in the lungs, heart abnormalities, inability to urinate, intestinal blockage, nasal congestion, restlessness, sedation, seizures, and shock.
image of a doctor in a lab doing drug, clinical research

Mellaril Novel Uses: Which Conditions Have a Clinical Trial Featuring Mellaril?

241 active clinical trials are presently examining the potential of Mellaril to alleviate Schizophrenia, Alzheimer's Disease and Schizophrenic Symptoms.
Condition
Clinical Trials
Trial Phases
Schizophrenia
34 Actively Recruiting
Early Phase 1, Not Applicable, Phase 4
Schizophrenia
174 Actively Recruiting
Not Applicable, Phase 3, Phase 2, Early Phase 1, Phase 4, Phase 1
Alzheimer's Disease
41 Actively Recruiting
Phase 2, Phase 3, Phase 4, Not Applicable, Phase 1

Mellaril Reviews: What are patients saying about Mellaril?

5Patient Review
10/24/2007
Mellaril for Schizophrenia
Millaril was much more effective than Seroquel in helping my anxiety and nervous habits, like pulling out my hair. And it's way cheaper too!
3.7Patient Review
5/7/2009
Mellaril for Schizophrenia
I'm starting to experience congestive heart failure.
1Patient Review
3/9/2008
Mellaril for Schizophrenia
I was misdiagnosed with Schizophrenia over 14 years ago and as a result, took Mellaril for an extended period of time. I have since stopped taking the medication, but have developed a heart condition because of it. This is extremely frustrating as I never actually had a mental illness to begin with.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about mellaril

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Mellaril still available?

"The Mellaril brand name has been discontinued, but there may be generic equivalents available in the US."

Answered by AI

What kind of drug is Mellaril?

"Mellaril is a medication used to treat psychotic disorders such as schizophrenia. It is usually given after other medications have been tried without successful treatment of schizophrenia."

Answered by AI

Is Mellaril the same as Thorazine?

"Thorazine and Mellaril are two different brands of drugs that have similar effects. Thorazine is a brand name for chlorpromazine, and thioridazine is the generic name of Mellaril. Both of these drugs are antipsychotics that work by blocking dopamine receptors in the brain."

Answered by AI

What is Mellaril prescribed for?

"It can reduce aggression and the desire to hurt others. It can reduce aggression and the desire to hurt others.

  1. This medication is used to treat certain mental/mood disorders (such as schizophrenia).

  2. This medication helps you to think more clearly, feel less nervous, and take part in everyday life.

  3. It can also help prevent suicide in people likely to harm themselves and reduce aggression and the desire to hurt others.

  4. It can reduce aggression and the desire to hurt others.

  5. It can reduce aggression and the desire to hurt others.

  6. This medication is a psychiatric medication (a type of drug) that works by restoring the balance of certain natural substances (neurotransmitters) in the brain.

  7. This medication is a psychiatric medication (a type of drug) that works by restoring the balance of certain natural substances (neurotransmitters) in the brain.

  8. This medication is a psychiatric medication (a type of drug) that works by restoring the balance of certain natural substances (neurotransmitters) in the brain.

  9. This medication is a psychiatric medication (a type of drug) that works by restoring the balance of certain natural substances (neurotransmitters) in the brain.

  10. This medication is a psychiatric medication (a type of drug) that works by restoring the balance of certain natural substances (neurotransmitters) in the brain.

  11. This medication is a psychiatric medication (a type of drug) that works by restoring the balance of certain natural substances (neurotransmitters) in the brain.

  12. This medication is a psychiatric medication (a type of drug) that works by restoring the balance of certain natural substances (neurotransmitters) in the brain."

Answered by AI

Clinical Trials for Mellaril

Have you considered Mellaril clinical trials? We made a collection of clinical trials featuring Mellaril, we think they might fit your search criteria.
Have you considered Mellaril clinical trials? We made a collection of clinical trials featuring Mellaril, we think they might fit your search criteria.
Have you considered Mellaril clinical trials? We made a collection of clinical trials featuring Mellaril, we think they might fit your search criteria.
Unbiased ResultsWe believe in providing patients with all the options.
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