Maxitrol

Q: How long does it take for Maxitrol drops to work?

<p>This medication contains two <a href="https://www.withpower.com/clinical-trials/antibiotics">antibiotics</a>, neomycin and polymyxin B. Maxitrol begins working immediately, as it is placed directly on the site of inflammation and infection.</p>

Pemphigus, Macular Edema, Iridocyclitis + 102 more

Treatment

106 FDA approvals

20 Active Studies for Maxitrol

Treatment for

Pemphigus

What is Maxitrol

DexamethasoneThe Generic name of this drug

Treatment SummaryNeomycin is an antibiotic drug used to treat a variety of bacterial infections. It is made up of three components, Neomycin A, B, and C. Neomycin B and C are the active components, while Neomycin A acts as a connector between the two. The drug works by binding to bacterial ribosomes and blocking their ability to make proteins, which is necessary for their survival. Neomycin sulfate is the most commonly used form of the drug and is available in oral solutions as well as otic and ophthalmic preparations. It can also be found in topical products over-the-counter.

Decadronis the brand name

image of different drug pills on a surface

Maxitrol Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Decadron

Dexamethasone

1958

452

Approved as Treatment by the FDA

Dexamethasone, also known as Decadron, is approved by the FDA for 106 uses which include Tuberculosis (TB) and Drug Allergy .

Tuberculosis (TB)

Helps manage Tuberculosis (TB)

Drug Allergy

Helps manage Drug hypersensitivity reaction

Seborrheic dermatitis

Helps manage Severe Seborrheic Dermatitis

Berylliosis

Helps manage Berylliosis

Ankylosing Spondylitis

Helps manage Ankylosing Spondylitis (AS)

Lymphoma, Non-Hodgkin

Helps manage Malignant Lymphomas

Crohn Disease

Helps manage Regional Enteritis

Lupus

Helps manage Systemic Lupus Erythematosus (SLE)

Multiple Myeloma

Used to treat Multiple Myeloma (MM) in combination with Isatuximab

Rhinitis, Allergic

Helps manage Perennial Allergic Rhinitis (PAR)

Hay Fever

Helps manage Seasonal Allergic Rhinitis

Choroiditis

Helps manage Choroiditis

Edema of the cerebrum

Helps manage Edema of the cerebrum

Mycosis Fungoides

Helps manage Mycosis Fungoides (MF)

Conjunctivitis

Helps manage anterior eye segment inflammation

Tennis Elbow

Helps manage Epicondylitis

Arthritis, Gouty

Helps manage Acute Gouty Arthritis

Degenerative polyarthritis

Helps manage Posttraumatic Osteoarthritis

Bursitis

Helps manage Bursitis

Cushing Syndrome

Anemia, Hemolytic

Helps manage acquired immune hemolytic anemia

Congenital adrenal hyperplasia

Helps manage Congenital Adrenal Hyperplasia (CAH)

Rheumatoid Arthritis, Juvenile

Helps manage Rheumatoid Arthritis, Juvenile

Atopic Dermatitis

Helps manage Atopic Dermatitis

Mycosis Fungoides (MF)

Helps manage Mycosis Fungoides (MF)

Tenosynovitis

Helps manage Tenosynovitis

Epicondylitis

Helps manage Epicondylitis

Asthma

Helps manage Asthma

Erythroblastopenia

Helps manage Erythroblastopenia

Immune Thrombocytopenia (ITP)

Helps manage Immune Thrombocytopenia (ITP)

Serum Sickness

Helps manage Serum Sickness

Berylliosis

Helps manage Berylliosis

Rheumatoid Arthritis

Helps manage Rheumatoid Arthritis

Malignant Lymphomas

Helps manage Malignant Lymphomas

Secondary thrombocytopenia

Helps manage Secondary thrombocytopenia

Regional Enteritis

Helps manage Regional Enteritis

Optic Neuritis

Helps manage Optic Neuritis

Congenital Adrenal Hyperplasia (CAH)

Helps manage Congenital Adrenal Hyperplasia (CAH)

Sarcoidosis

Helps manage Sarcoidosis

Synovitis

Helps manage Synovitis

Uveitis

Helps manage Uveitis

Chorioretinitis

Helps manage Chorioretinitis

non-suppurative Thyroiditis

Helps manage non-suppurative Thyroiditis

Ophthalmia, Sympathetic

Helps manage Ophthalmia, Sympathetic

Optic Neuritis

Helps manage Optic Neuritis

Adrenal Insufficiency

Helps manage Adrenal cortical hypofunctions

Congenital Hypoplastic Anemia

Helps manage Congenital Hypoplastic Anemia

Aspiration Pneumonitis

Helps manage Aspiration Pneumonitis

Acute Leukemia (Category)

Helps manage Acute Leukemia (Category)

Acute Coryza

Helps manage acute rheumatic carditis

Keratitis

Helps manage Keratitis

Iridocyclitis

Helps manage Iridocyclitis

Bursitis

Helps manage Bursitis

Ankylosing Spondylitis (AS)

Helps manage Ankylosing Spondylitis (AS)

Synovitis

Helps manage Synovitis

anterior eye segment inflammation

Helps manage anterior eye segment inflammation

Choroiditis

Helps manage Choroiditis

Cancer

Helps manage Cancer

Hypercalcemia

Helps manage Hypercalcemia

Trichinosis

Helps manage Trichinosis

Adrenal cortical hypofunctions

Helps manage Adrenal cortical hypofunctions

Multiple Myeloma (MM)

Used to treat Multiple Myeloma (MM) in combination with Isatuximab

Drug hypersensitivity reaction

Helps manage Drug hypersensitivity reaction

Adrenocortical Hyperfunction

Trialled at least two prior therapies including lenalidomide and a proteasome inhibitor

Used to treat Trialled at least two prior therapies including lenalidomide and a proteasome inhibitor in combination with Isatuximab

Perennial Allergic Rhinitis (PAR)

Helps manage Perennial Allergic Rhinitis (PAR)

Inflammation

Seasonal Allergic Rhinitis

Helps manage Seasonal Allergic Rhinitis

Systemic Lupus Erythematosus (SLE)

Helps manage Systemic Lupus Erythematosus (SLE)

Ulcerative Colitis

Helps manage Ulcerative Colitis

severe Psoriasis

Helps manage severe Psoriasis

Contact Dermatitis

Helps manage Contact Dermatitis

acquired immune hemolytic anemia

Helps manage acquired immune hemolytic anemia

Tuberculosis

Helps manage Tuberculosis (TB)

Loeffler's syndrome

Helps manage Loeffler's syndrome

Pemphigus

Helps manage Pemphigus

Uveitis

Helps manage Uveitis

Iritis

Helps manage Iritis

Acute Gouty Arthritis

Helps manage Acute Gouty Arthritis

Posttraumatic Osteoarthritis

Helps manage Posttraumatic Osteoarthritis

Hypercalcemia

Helps manage Hypercalcemia

Asthma

Helps manage Asthma

Rosacea

Helps manage Rosacea

Adrenal Gland Hyperfunction

Brain

Helps manage Edema of the cerebrum

Inflammation

Severe Seborrheic Dermatitis

Helps manage Severe Seborrheic Dermatitis

exfoliative erythroderma

Helps manage exfoliative erythroderma

Iridocyclitis

Helps manage Iridocyclitis

Stevens-Johnson Syndrome

Helps manage Stevens-Johnson Syndrome

Cushing's Syndrome

Ulcerative Colitis

Helps manage Ulcerative Colitis

Iritis

Helps manage Iritis

Pulmonary Eosinophilia

Helps manage Loeffler's syndrome

Allergic Conjunctivitis (AC)

Helps manage Allergic Conjunctivitis (AC)

Anemia, Diamond-Blackfan

Helps manage Congenital Hypoplastic Anemia

Arthritis, Juvenile

Helps manage Rheumatoid Arthritis, Juvenile

Acute Myeloid Leukemia (AML)

Helps manage Acute Leukemia (Category)

varicella-zoster virus acute retinal necrosis

Helps manage varicella-zoster virus acute retinal necrosis

Rosacea

Helps manage Rosacea

Multiple Myeloma

Used to treat Trialled at least two prior therapies including lenalidomide and a proteasome inhibitor in combination with Isatuximab

Bullous dermatitis herpetiformis

Helps manage Bullous dermatitis herpetiformis

Thrombocytopenia

Helps manage Secondary thrombocytopenia

Pemphigus

Helps manage Pemphigus

Thyroiditis

Helps manage non-suppurative Thyroiditis

Psoriasis

Helps manage severe Psoriasis

Effectiveness

How Maxitrol Affects PatientsNeomycin is a medication that stops bacteria from making proteins, which can prevent the growth and survival of certain types of bacteria. After taking it orally, it usually stays in the body for up to 72 hours and can reduce the amount of bacteria that produce ammonia. Neomycin is effective against both gram positive and gram negative bacteria, including the common types of E. coli found in the colon, as well as certain types of Klebsiella and Proteus. In some cases, the bacteria may become resistant to neomycin, but it has no effect on fungi or some protozoa.

How Maxitrol works in the bodyNeomycin is an antibiotic that stops bacteria from making proteins. It does this by binding to the ribosomes of the bacteria, disrupting their ability to build proteins from mRNA. This prevents the bacteria from growing and multiplying.

When to interrupt dosage

The suggested portion of Maxitrol is contingent upon the diagnosed affliction, including Itching brought about by Infection, Secondarily Infected Eczema and Communicable Diseases. The quantity of dosage can be found in the table below, contingent upon the technique of delivery (e.g. Suspension - Auricular (otic) or Topical).

Condition

Dosage

Administration

Hypercalcemia

, 0.7 mg, 0.001 mg/mg, 10.0 mg/mL, 4.0 mg/mL, 1.5 mg, 1.0 mg/mL, 4.0 mg, 0.75 mg, 1.0 mg, 2.0 mg, 6.0 mg, 0.5 mg, 0.5 mg/mL, 0.1 %, 40.0 mg, 0.0005 mg/mg, 517.0 mg/mL, 0.0015 mg/mg, 0.4 mg, 20.0 mg, 0.1 mg/mL, 0.5 mg/units

, Implant, Implant - Intravitreal, Intravitreal, Ointment, Ointment - Ophthalmic, Ophthalmic, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Injection, solution, Intra-articular; Intralesional; Intramuscular; Intravenous; Soft tissue, Injection, solution - Intra-articular; Intralesional; Intramuscular; Intravenous; Soft tissue, Oral, Tablet, Tablet - Oral, Solution / drops - Ophthalmic, Solution / drops, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Suspension, Suspension / drops, Solution, Solution - Ophthalmic, Auricular (otic), Suspension - Auricular (otic), Intramuscular, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Injection, Intra-articular; Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Elixir, Elixir - Oral, Liquid, Liquid - Intramuscular; Intravenous, Intramuscular; Intrasynovial; Intravenous, Liquid - Intramuscular; Intrasynovial; Intravenous, Liquid - Intra-articular; Intralesional; Intramuscular; Intravenous; Soft tissue, Auricular (otic); Ophthalmic, Solution / drops - Auricular (otic); Ophthalmic, Solution - Intramuscular; Intrasynovial; Intravenous, Solution - Auricular (otic); Ophthalmic, Solution - Intra-articular; Intramuscular; Intravenous, Topical, Solution / drops - Topical, Ophthalmic; Topical, Liquid - Ophthalmic; Topical, Ointment - Topical, Liquid - Auricular (otic); Ophthalmic, Ointment - Auricular (otic); Ophthalmic, Solution - Intra-articular; Intralesional; Intramuscular; Intravenous; Soft tissue, Solution - Intramuscular; Intravenous, Liquid - Intra-articular; Intramuscular; Intravenous, Solution, concentrate, Solution, concentrate - Oral, Solution - Oral, Suspension / drops - Auricular (otic), Injection - Intra-articular; Intralesional; Intramuscular; Intravenous; Soft tissue, Dental, Liquid - Dental, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Injection - Intramuscular, Solution - Parenteral, Parenteral, Injection, solution - Ophthalmic, Intraocular, Injection, solution - Intraocular, Injection, suspension, Injection, suspension - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, suspension - Intra-articular; Intralesional; Intramuscular; Intravenous; Soft tissue, Intramuscular; Intravenous; Topical, Kit - Intramuscular; Intravenous; Topical, Injection, emulsion, Injection, emulsion - Intramuscular; Intravenous, Insert, Insert - Ophthalmic, Solution - Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Perineural; Topical, Epidural; Infiltration; Intramuscular; Intravenous; Perineural; Topical, Perineural, Suspension / drops - Topical

Anemia, Hemolytic

Pulmonary Eosinophilia

Otitis Media

Necrobiosis Lipoidica

Uveitis

Open-angle glaucoma

Pink Eye

Erythroblastopenia

Tennis Elbow

Bursitis

varicella-zoster virus acute retinal necrosis

Atopic Dermatitis

Bullous dermatitis herpetiformis

Granuloma Annulare

Acute Coryza

Rosacea

Neurodermatitis

Arthritis, Gouty

Brain

Warnings

Maxitrol has nine contraindications and should not be administered when encountering any of the situations specified in the table below.Maxitrol Contraindications

Condition

Risk Level

Notes

active periocular infections

Do Not Combine

Eye

Do Not Combine

Tympanic membrane structure

Do Not Combine

suspected periocular infections

Do Not Combine

Eye Infections, Fungal

Do Not Combine

Viral Conjunctivitis

Do Not Combine

Communicable Diseases

Do Not Combine

Eye Infection

Do Not Combine

Mycoses

Do Not Combine

Chickenpox

Do Not Combine

External auditory canal structure

Do Not Combine

epithelial herpes simplex keratitis

Do Not Combine

External Ear

Do Not Combine

torn posterior lens

Do Not Combine

Open-angle glaucoma

Do Not Combine

Cornea

Do Not Combine

Eye Infections

Do Not Combine

ruptured posterior lens

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Dexamethasone may interact with Pulse Frequency

There are 20 known major drug interactions with Maxitrol.

Common Maxitrol Drug Interactions

Drug Name

Risk Level

Description

1,2-Benzodiazepine

Major

The metabolism of 1,2-Benzodiazepine can be increased when combined with Dexamethasone.

2-Methoxyethanol

Major

The risk or severity of adverse effects can be increased when Dexamethasone is combined with 2-Methoxyethanol.

3,5-diiodothyropropionic acid

Major

The metabolism of 3,5-diiodothyropropionic acid can be increased when combined with Dexamethasone.

6-O-benzylguanine

Major

The metabolism of 6-O-benzylguanine can be increased when combined with Dexamethasone.

7-ethyl-10-hydroxycamptothecin

Major

The metabolism of 7-ethyl-10-hydroxycamptothecin can be increased when combined with Dexamethasone.

Maxitrol Toxicity & Overdose RiskNeomycin has been found to be toxic in mice when given orally, with a dose of over 8g/kg. The toxic doses in rats and mice when given through the skin are 200mg/kg and 190mg/kg, respectively. When given through the abdomen, the toxic dose is 305mg/kg in mice. In humans, the toxic dose for women is 12600mg/kg over 7 days. It is unlikely that acute overdosage will occur due to the low absorption rate of neomycin. However, it is important to avoid long-term use as it can lead to neurotoxicity, ototoxicity

image of a doctor in a lab doing drug, clinical research

Maxitrol Novel Uses: Which Conditions Have a Clinical Trial Featuring Maxitrol?

405 active trials are presently being conducted to evaluate the potential of Maxitrol in diminishing Inflammation, Atopic Dermatitis and other Atopic Dermatitis related conditions.

Condition

Clinical Trials

Trial Phases

Otitis Externa

0 Actively Recruiting

Trichinosis

0 Actively Recruiting

Tuberculosis

7 Actively Recruiting

Phase 2, Phase 3, Not Applicable, Phase 4

Urinary Tract Infection (UTI)

9 Actively Recruiting

Phase 1, Phase 3, Phase 4, Not Applicable

Bacterial Infections

0 Actively Recruiting

Lupus Erythematosus, Discoid

2 Actively Recruiting

Phase 2

Acute Coryza

0 Actively Recruiting

Lupus

57 Actively Recruiting

Phase 2, Phase 1, Not Applicable, Phase 3, Phase 4

Open-angle glaucoma

42 Actively Recruiting

Not Applicable, Phase 2, Phase 4, Early Phase 1, Phase 1

Inflammation

64 Actively Recruiting

Not Applicable, Early Phase 1, Phase 1, Phase 2, Phase 3, Phase 4

Ocular Itching

0 Actively Recruiting

Rheumatoid Arthritis

54 Actively Recruiting

Not Applicable, Phase 4, Phase 3, Phase 2, Phase 1

Acute Myeloid Leukemia (AML)

36 Actively Recruiting

Phase 1, Phase 2, Not Applicable, Phase 3

Asthma

88 Actively Recruiting

Phase 4, Early Phase 1, Phase 2, Not Applicable, Phase 1, Phase 3

Ulcerative Colitis

13 Actively Recruiting

Phase 3, Not Applicable, Phase 2, Phase 1

Diabetic Macular Edema

24 Actively Recruiting

Not Applicable, Phase 3, Phase 2, Phase 4, Phase 1

Uveitis

2 Actively Recruiting

Not Applicable, Phase 3

Thyroiditis

0 Actively Recruiting

Neurodermatitis

0 Actively Recruiting

Otitis Media

0 Actively Recruiting

Maxitrol Reviews: What are patients saying about Maxitrol?

2.7Patient Review

10/24/2008

Maxitrol for Inflammation of Eyelid Edges and the Lining of the Eye

This didn't work for me at all. My eye was still itchy and watering when I used this treatment.

2.7Patient Review

11/16/2007

Maxitrol for Scratch Wound on Cornea

I experienced swelling, mouth sores, and redness while taking this medication. Additionally, I had issues with dry mouth.

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about maxitrol

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Maxitrol used to treat?

"Before your doctor prescribes Maxitrol Eye Drops, they will examine your eye(s) to ensure that the medicine is right for you. Maxitrol Eye Drops are used to treat inflammation and bacterial infections in the external part of the eye."

Answered by AI

Is Maxitrol ointment an antibiotic?

"The active ingredients in Maxitrol Eye Ointment are dexamethasone, neomycin and polymyxin B. Neomycin and polymyxin B are both antibiotic agents."

Answered by AI

How long does it take for Maxitrol drops to work?

"This medication contains two antibiotics, neomycin and polymyxin B. Maxitrol begins working immediately, as it is placed directly on the site of inflammation and infection."

Answered by AI

Is Maxitrol safe for eyes?

"If you use Maxitrol for a long time, you might get a new type of fungal eye infection. You might also have a greater chance of other eye problems, such as glaucoma, cataracts, or delayed healing of wounds."

Answered by AI

Clinical Trials for Maxitrol

Have you considered Maxitrol clinical trials? We made a collection of clinical trials featuring Maxitrol, we think they might fit your search criteria.

Have you considered Maxitrol clinical trials? We made a collection of clinical trials featuring Maxitrol, we think they might fit your search criteria.