Locoid

Pruritus, Pruritus, corticosteroid responsive, Inflammatory Dermatosis
Treatment
3 FDA approvals
0 Active Studies for Locoid

What is Locoid

Hydrocortisone butyrateThe Generic name of this drug
Hydrocortisone Butyrateis the brand name
Locoid Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Hydrocortisone Butyrate
Hydrocortisone butyrate
1987
34

Approved as Treatment by the FDA

Hydrocortisone butyrate, also known as Hydrocortisone Butyrate, is approved by the FDA for 3 uses like corticosteroid responsive, Inflammatory Dermatosis and Pruritus .
corticosteroid responsive, Inflammatory Dermatosis
Pruritus
Pruritus

Effectiveness

How Locoid Affects PatientsHydrocortisone is a steroid hormone that is essential for life, helping to regulate and support a variety of functions in the body. It is often used as a cream to treat skin inflammation. Glucocorticoids like hydrocortisone work to suppress cell-mediated immunity, meaning they stop the production of certain proteins that cause inflammation. They also reduce the production of another protein (IL-2) that helps activate T and B lymphocytes, which are cells involved in the immune system. As a result, these cells are less likely to be activated and cause inflammation.
How Locoid works in the bodyHydrocortisone works by binding to a receptor in cells and causing them to produce proteins that help reduce inflammation. This protein, also called lipocortin, helps stop the production of substances that lead to inflammation, like prostaglandins and leukotrienes. It also reduces the ability of the immune system to cause inflammation by decreasing the activity of the lymphatic system, reducing immunoglobulin and complement concentrations, and preventing antigen-antibody binding.

When to interrupt dosage

The quantity of Locoid is contingent upon the recognized affliction, including Atopic Dermatitis, Pruritus and corticosteroid responsive, Inflammatory Dermatosis. The amount of dosage fluctuates as per the technique of delivery (e.g. Cream or Patch - Cutaneous) featured in the table beneath.
Condition
Dosage
Administration
Pruritus
, 0.001 mg/mg, 1.0 mg/mL, 0.0016 mg/hour, 0.00003 mg/mg, 0.003 mg/mg
, Topical, Cream, Cream - Topical, Ointment, Ointment - Topical, Solution, Solution - Topical, Lotion, Lotion - Topical, Cutaneous, Patch - Cutaneous, Patch
corticosteroid responsive, Inflammatory Dermatosis
, 0.001 mg/mg, 1.0 mg/mL, 0.0016 mg/hour, 0.00003 mg/mg, 0.003 mg/mg
, Topical, Cream, Cream - Topical, Ointment, Ointment - Topical, Solution, Solution - Topical, Lotion, Lotion - Topical, Cutaneous, Patch - Cutaneous, Patch
Pruritus
, 0.001 mg/mg, 1.0 mg/mL, 0.0016 mg/hour, 0.00003 mg/mg, 0.003 mg/mg
, Topical, Cream, Cream - Topical, Ointment, Ointment - Topical, Solution, Solution - Topical, Lotion, Lotion - Topical, Cutaneous, Patch - Cutaneous, Patch

Warnings

There are 20 known major drug interactions with Locoid.
Common Locoid Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The metabolism of Abemaciclib can be increased when combined with Hydrocortisone butyrate.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be increased when combined with Hydrocortisone butyrate.
Alectinib
Major
The metabolism of Alectinib can be increased when combined with Hydrocortisone butyrate.
Alpelisib
Major
The metabolism of Alpelisib can be increased when combined with Hydrocortisone butyrate.
Aminophylline
Major
The metabolism of Aminophylline can be increased when combined with Hydrocortisone butyrate.
Locoid Toxicity & Overdose RiskTaking too much of this drug can lead to reduced bone growth, decreased calcium absorption, and slower healing of wounds.
image of a doctor in a lab doing drug, clinical research

Locoid Novel Uses: Which Conditions Have a Clinical Trial Featuring Locoid?

67 active studies are being conducted to investigate the potential of Locoid in treating Atopic Dermatitis, Pruritus and corticosteroid responsive Inflammatory Dermatoses.
Condition
Clinical Trials
Trial Phases
Pruritus
0 Actively Recruiting
Pruritus
0 Actively Recruiting
corticosteroid responsive, Inflammatory Dermatosis
0 Actively Recruiting

Locoid Reviews: What are patients saying about Locoid?

5Patient Review
9/4/2009
Locoid for Inflammation of Skin caused by an Allergy
I had really bad redness, bumps, and itchiness on my face. This went away within a few days of using the treatment. I've only experienced positive results and would recommend it to others!
4.3Patient Review
12/6/2013
Locoid for Reddish Nodules Arranged in a Circle On the Skin
I found relief after the first application of this treatment.

Patient Q&A Section about locoid

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Locoid cream a steroid?

"Locoid Lipocream (hydrocortisone butyrate) is a steroid cream used topically to treat inflammation of the skin caused by various conditions such as allergies, eczema, or psoriasis."

Answered by AI

What is Locoid cream used to treat?

"The cream can be used on adults, children, and infants who are at least 3 months old for the treatment of inflammatory skin disorders that are not caused by microorganisms, such as eczema, dermatitis, and psoriasis."

Answered by AI

Is Locoid a strong steroid?

"Topical corticosteroids are divided into four categories according to their strength: mild, moderate, potent, and very potent. Locoid Lipocream is in the potent category. Topical corticosteroids can reduce the inflammation caused by various skin conditions and help the skin heal."

Answered by AI