Lithobid

Bipolar Disorder, Acute Coryza, Bipolar Disorder

Treatment

0 Active Studies for Lithobid

Treatment for

Bipolar Disorder

What is Lithobid

Lithium carbonate

The Generic name of this drug

Treatment Summary

Lithium has been used to treat manic episodes for over a century. Its exact method of action is still unknown, but it is known that lithium carbonate has a small therapeutic range and needs to be closely monitored to prevent negative side effects.

Eskalith

is the brand name

image of different drug pills on a surface

Lithobid Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Eskalith

Lithium carbonate

1970

174

Effectiveness

How Lithobid Affects Patients

The exact way lithium works is still not completely understood, but it is thought to help by stopping certain enzymes from working, and by changing how the brain responds to a chemical called glutamate.

How Lithobid works in the body

The exact way lithium works is not yet known, but there are several potential pathways. The “inositol depletion theory” suggests that lithium affects inositol monophosphatase, inositol polyphosphatase, and glycogen synthase kinase 3 (GSK-3). Lithium is an uncompetitive inhibitor of inositol monophosphatase, decreasing the amount of inositol triphosphate in the body. Low levels of inositol triphosphate have been linked to memory impairment. Lithium also acts as an uncompetitive inhibitor of inositol polyphosph

When to interrupt dosage

The proposed dosage of Lithobid is dependent on the established condition. The measure of dosage can be found in the table below, contingent upon the method of administration (e.g. Oral or Tablet, extended release - Oral).

Condition

Dosage

Administration

Bipolar Disorder

, 300.0 mg, 150.0 mg, 600.0 mg, 450.0 mg, 400.0 mg, 250.0 mg, 8.0 meq/mL

Oral, , Tablet, Tablet, extended release, Capsule, Capsule - Oral, Tablet, extended release - Oral, Tablet - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Solution, Solution - Oral

Acute Coryza

, 300.0 mg, 150.0 mg, 600.0 mg, 450.0 mg, 400.0 mg, 250.0 mg, 8.0 meq/mL

Bipolar Disorder

, 300.0 mg, 150.0 mg, 600.0 mg, 450.0 mg, 400.0 mg, 250.0 mg, 8.0 meq/mL

Warnings

Lithobid Contraindications

Condition

Risk Level

Notes

Severe Hypersensitivity Reactions

Do Not Combine

Lithium Carbonate may interact with Pulse Frequency

There are 20 known major drug interactions with Lithobid.

Common Lithobid Drug Interactions

Drug Name

Risk Level

Description

Azelastine

Major

Lithium carbonate may increase the central nervous system depressant (CNS depressant) activities of Azelastine.

Ethanol

Major

Lithium carbonate may increase the central nervous system depressant (CNS depressant) activities of Ethanol.

Neomycin

Major

The risk or severity of nephrotoxicity can be increased when Lithium carbonate is combined with Neomycin.

Oliceridine

Major

The risk or severity of hypotension, sedation, death, somnolence, and respiratory depression can be increased when Lithium carbonate is combined with Oliceridine.

Tenofovir

Major

Lithium carbonate may increase the nephrotoxic activities of Tenofovir.

Lithobid Toxicity & Overdose Risk

The toxic dose of lithium carbonate in rats is 525mg/kg. There is not enough evidence to determine if lithium carbonate is carcinogenic, mutagenic, or affects fertility. However, studies have shown that repeated doses of lithium carbonate can have negative effects on male reproductive organs and testosterone levels. There is conflicting evidence about cardiovascular problems with lithium use in the first trimester of pregnancy. Animal studies suggest that it can be dangerous for the fetus and fertility, so the risks and benefits must be weighed before using it. Breastfeeding while taking lithium should be avoided, but if it is continued the infant should be monitored for thyroid function

image of a doctor in a lab doing drug, clinical research

Lithobid Novel Uses: Which Conditions Have a Clinical Trial Featuring Lithobid?

Two active investigations are currently underway to ascertain the potential of Lithobid in alleviating Acute Coryza.

Condition

Clinical Trials

Trial Phases

Bipolar Disorder

0 Actively Recruiting

Bipolar Disorder

0 Actively Recruiting

Acute Coryza

1 Actively Recruiting

Not Applicable

Lithobid Reviews: What are patients saying about Lithobid?

Patient Review

2/21/2009

Lithobid for Bipolar Disorder in Remission

I've been taking this for 20 years and it's been working great, minus some occasional stomach issues.

Patient Review

12/23/2009

Lithobid for Mania associated with Bipolar Disorder

This medication has been the only one I can tolerate for my bipolar disorder. It helps to control my extremes, though I wish it helped me function better. Unfortunately, it also comes with weight gain as a side effect.

Patient Review

2/12/2008

Lithobid for Manic-Depression

4.7

Patient Review

7/26/2011

Lithobid for Additional Medications to Treat Depression

The only downsides are having to get bloodwork done, and increased thirst and urination. But for me, it was TOTALLY worth it! I am truly a new person today! The happiest I've been in years! And it worked in only 2 weeks!

4.3

Patient Review

8/10/2012

Lithobid for Mania associated with Bipolar Disorder

I feel pretty stable on this medication. No huge ups or downs, which is a relief. I'm thankful that Obama care will help me afford it until 2014 when I can get insurance through my job.

4.3

Patient Review

5/17/2008

Lithobid for Bipolar Depression

Lithobid has been effective for me, though I have noticed an increase in my weight since starting the medication.

4.3

Patient Review

5/3/2010

Lithobid for Manic-Depression

For the last 20 years, lithium has been a total game-changer for me. The only side effect I've experienced is a slight hand tremor, but my doctor was able to prescribe medication that took care of that. Overall, I couldn't be happier with the results.

Patient Review

3/26/2008

Lithobid for Bipolar Depression

Patient Review

1/14/2009

Lithobid for Bipolar Depression

The only downside to this treatment is that it caused some mild stomach cramping and pregnancy symptoms.

2.3

Patient Review

10/19/2009

Lithobid for Mania associated with Bipolar Disorder

I've been on this medication for a while now and it's not great. I experience terrible mood swings and have gained a lot of weight.

2.3

Patient Review

10/16/2008

Lithobid for Bipolar Depression

It caused a lot of swelling for me.

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about lithobid

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Lithobid the same as lithium?

"The drug Lithobid contains lithium carbonate, a white, odorless, alkaline powder. Lithium is a chemical element in the alkali-metal group. Its atomic number is 3, atomic weight is 6.94, and it has an emission line at 671 nm on the flame photometer."

Answered by AI

What does lithium do to a person?

"Lithium is a medicine known as a mood stabiliser, used to treat mood disorders such as mania, hypo-mania, and depression."

Answered by AI

What is Lithobid used to treat?

"This medication is used to treat bipolar disorder by restoring the balance of certain natural substances (neurotransmitters) in the brain."

Answered by AI

Is Lithobid an antidepressant?

"Lithobid is a mood stabilizer that is used to treat or control bipolar disorder. Manic symptoms include hyperactivity, rushed speech, poor judgment, reduced need for sleep, aggression, and anger. This medicine also helps to prevent or lessen the intensity of manic episodes."

Answered by AI