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What is Lithobid
Lithium carbonateThe Generic name of this drug
Treatment SummaryLithium has been used to treat manic episodes for over a century. Its exact method of action is still unknown, but it is known that lithium carbonate has a small therapeutic range and needs to be closely monitored to prevent negative side effects.
Eskalithis the brand name
Lithobid Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Eskalith
Lithium carbonate
1970
174
Effectiveness
How Lithobid Affects PatientsThe exact way lithium works is still not completely understood, but it is thought to help by stopping certain enzymes from working, and by changing how the brain responds to a chemical called glutamate.
How Lithobid works in the bodyThe exact way lithium works is not yet known, but there are several potential pathways. The “inositol depletion theory” suggests that lithium affects inositol monophosphatase, inositol polyphosphatase, and glycogen synthase kinase 3 (GSK-3). Lithium is an uncompetitive inhibitor of inositol monophosphatase, decreasing the amount of inositol triphosphate in the body. Low levels of inositol triphosphate have been linked to memory impairment. Lithium also acts as an uncompetitive inhibitor of inositol polyphosph
When to interrupt dosage
The proposed dosage of Lithobid is dependent on the established condition. The measure of dosage can be found in the table below, contingent upon the method of administration (e.g. Oral or Tablet, extended release - Oral).Condition
Dosage
Administration
Bipolar Disorder
, 300.0 mg, 150.0 mg, 600.0 mg, 450.0 mg, 400.0 mg, 250.0 mg, 8.0 meq/mL
, Tablet, extended release, Oral, Tablet, extended release - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Solution, Solution - Oral
Bipolar Disorder
, 300.0 mg, 150.0 mg, 600.0 mg, 450.0 mg, 400.0 mg, 250.0 mg, 8.0 meq/mL
, Tablet, extended release, Oral, Tablet, extended release - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Solution, Solution - Oral
Acute Coryza
, 300.0 mg, 150.0 mg, 600.0 mg, 450.0 mg, 400.0 mg, 250.0 mg, 8.0 meq/mL
, Tablet, extended release, Oral, Tablet, extended release - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Solution, Solution - Oral
Warnings
Lithobid ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Lithium Carbonate may interact with Pulse Frequency
Common Lithobid Drug Interactions
Drug Name
Risk Level
Description
Azelastine
Major
Lithium carbonate may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Ethanol
Major
Lithium carbonate may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Neomycin
Major
The risk or severity of nephrotoxicity can be increased when Lithium carbonate is combined with Neomycin.
Oliceridine
Major
The risk or severity of hypotension, sedation, death, somnolence, and respiratory depression can be increased when Lithium carbonate is combined with Oliceridine.
Tenofovir
Major
Lithium carbonate may increase the nephrotoxic activities of Tenofovir.
Lithobid Toxicity & Overdose RiskThe toxic dose of lithium carbonate in rats is 525mg/kg. There is not enough evidence to determine if lithium carbonate is carcinogenic, mutagenic, or affects fertility. However, studies have shown that repeated doses of lithium carbonate can have negative effects on male reproductive organs and testosterone levels. There is conflicting evidence about cardiovascular problems with lithium use in the first trimester of pregnancy. Animal studies suggest that it can be dangerous for the fetus and fertility, so the risks and benefits must be weighed before using it. Breastfeeding while taking lithium should be avoided, but if it is continued the infant should be monitored for thyroid function
Lithobid Novel Uses: Which Conditions Have a Clinical Trial Featuring Lithobid?
Two active investigations are currently underway to ascertain the potential of Lithobid in alleviating Acute Coryza.Condition
Clinical Trials
Trial Phases
Bipolar Disorder
1 Actively Recruiting
Phase 4
Bipolar Disorder
0 Actively Recruiting
Acute Coryza
1 Actively Recruiting
Not Applicable
Lithobid Reviews: What are patients saying about Lithobid?
5Patient Review
2/21/2009 I've been taking this for 20 years and it's been working great, minus some occasional stomach issues.
5Patient Review
12/23/2009 This medication has been the only one I can tolerate for my bipolar disorder. It helps to control my extremes, though I wish it helped me function better. Unfortunately, it also comes with weight gain as a side effect.
5Patient Review
2/12/20084.7Patient Review
7/26/2011 The only downsides are having to get bloodwork done, and increased thirst and urination. But for me, it was TOTALLY worth it! I am truly a new person today! The happiest I've been in years! And it worked in only 2 weeks!
4.3Patient Review
8/10/2012 I feel pretty stable on this medication. No huge ups or downs, which is a relief. I'm thankful that Obama care will help me afford it until 2014 when I can get insurance through my job.
4.3Patient Review
5/17/2008 Lithobid has been effective for me, though I have noticed an increase in my weight since starting the medication.
4.3Patient Review
5/3/2010 For the last 20 years, lithium has been a total game-changer for me. The only side effect I've experienced is a slight hand tremor, but my doctor was able to prescribe medication that took care of that. Overall, I couldn't be happier with the results.
4Patient Review
3/26/20083Patient Review
1/14/2009 The only downside to this treatment is that it caused some mild stomach cramping and pregnancy symptoms.
2.3Patient Review
10/19/2009 I've been on this medication for a while now and it's not great. I experience terrible mood swings and have gained a lot of weight.
2.3Patient Review
10/16/2008 It caused a lot of swelling for me.
Patient Q&A Section about lithobid
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Lithobid the same as lithium?
"The drug Lithobid contains lithium carbonate, a white, odorless, alkaline powder. Lithium is a chemical element in the alkali-metal group. Its atomic number is 3, atomic weight is 6.94, and it has an emission line at 671 nm on the flame photometer."
Answered by AI
What does lithium do to a person?
"Lithium is a medicine known as a mood stabiliser, used to treat mood disorders such as mania, hypo-mania, and depression."
Answered by AI
What is Lithobid used to treat?
"This medication is used to treat bipolar disorder by restoring the balance of certain natural substances (neurotransmitters) in the brain."
Answered by AI
Is Lithobid an antidepressant?
"Lithobid is a mood stabilizer that is used to treat or control bipolar disorder. Manic symptoms include hyperactivity, rushed speech, poor judgment, reduced need for sleep, aggression, and anger. This medicine also helps to prevent or lessen the intensity of manic episodes."
Answered by AI