What is Kerydin
TavaboroleThe Generic name of this drug
Treatment SummaryTavaborole is a topical antifungal medication used to treat onychomycosis, a fungal infection of the nail and nail bed. This medication works by blocking an essential fungal enzyme known as Leucyl-tRNA synthetase, which is necessary for protein synthesis and for attaching L-leucine to tRNA(Leu). Tavaborole is specifically used to treat infections caused by *Trichophyton rubrum* and *Trichophyton mentagrophytes*.
Kerydinis the brand name
Kerydin Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Kerydin
Tavaborole
2014
15
Effectiveness
How Kerydin Affects PatientsAfter one dose, the highest amount of tavaborole in the bloodstream was usually around 3.54 ng/mL (range 0.618-10.2 ng/mL). After taking the drug daily for two weeks, the highest amount of tavaborole in the bloodstream was around 5.17 ng/mL (range 1.51-12.8 ng/mL).
How Kerydin works in the bodyTavaborole works by preventing cells from making proteins. It binds to a type of transfer RNA and blocks it from making proteins in the cell.
When to interrupt dosage
The suggested dosage of Kerydin depends on the identified state. The measure can also be found in the table below, contingent upon the method of delivery (e.g. Topical or Liquid - Topical).Condition
Dosage
Administration
Onychomycosis
, 43.5 mg/mL
Topical, Liquid - Topical, Solution - Topical, , Solution, Liquid
Warnings
Common Kerydin Drug Interactions
Drug Name
Risk Level
Description
Kerydin Toxicity & Overdose RiskTaking tavaborole is usually safe and causes few side effects. In some cases, people experience mild skin reactions such as peeling, redness, or inflammation at the application site. Ingrown toenails may also occur in more than one percent of users.
Kerydin Novel Uses: Which Conditions Have a Clinical Trial Featuring Kerydin?
Six clinical trials are presently being conducted to evaluate Kerydin's capacity to address Onychomycosis.Condition
Clinical Trials
Trial Phases
Onychomycosis
3 Actively Recruiting
Phase 2, Phase 3, Phase 1
Kerydin Reviews: What are patients saying about Kerydin?
5Patient Review
1/25/2017 I have had toenail fungus for two decades now, and this is the only treatment that has worked for me. I started using it about a year ago and my nails are now healthy and clear. The only downside is that I've experienced some peeling skin, but it's a small price to pay for clear nails!
5Patient Review
9/15/2017 I started using this treatment in November 2016 and had a $0 copay for the first 3 months. The price then went up to over $450, so I unfortunately had to stop using it. However, even just using a tiny drop of the product once per day cleared my big toe completely of fungus within that time period!
5Patient Review
1/30/2020 Kerydin was the only thing that worked for me when it came to getting rid of my fungus.
4.7Patient Review
9/8/2016 Kerydin was my last resort and I'm glad I tried it. In just five months, it's completely cleared up my toenail fungus. The only downside is the cost of the medication.
3.7Patient Review
11/12/2015 This is clearing up the fungus I've had for many years. It's helpful to have someone apply it for me.
3.7Patient Review
11/16/2015 Even though it's easy to accidentally spill, this is a very effective treatment -- but be patient, because it can take up to four years to see full results.
3.3Patient Review
5/24/2016 I've been using this medication for half a year now, and I'm only just beginning to see results. The yellowing from the fungal infection is slowly starting to fade, but I still have a ways to go.
3.3Patient Review
6/21/2016 So far, this treatment has cleared up one toenail. I haven't seen a difference on the other yet, but it's only been a few weeks. It's very expensive (over $400 per bottle), but the company will work with you for a few bottles. I've also started using orange sticks, tossing them when done with each affected toe and clippers and other nail instruments get set in alcohol or anti fungal cleaner!
2.7Patient Review
5/20/2019 I had to use this everyday for 40 weeks. It seemed to clear up the severe cracking/ breaking of my big toenails but did not clear it up completely. I used it as directed. Now my toenails are still yellowed and break easily, are impossible to cut or file without breakage, and are brittle. My insurance paid over $900 for a tiny bottle that I had to pay $50 copay.
2Patient Review
10/6/2015 Measuring and dispensing the medication is quite difficult and easy to make a mess with. I didn't notice any improvement in my nails and overall it was quite unsuccessful based on other reviews I've read. It's also very overpriced.
Patient Q&A Section about kerydin
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.How effective is Kerydin for toenail fungus?
"There two main types of antifungal agents, Jublia (efinaconazole) and Kerydin (tacaborole). Jublia was applied daily for 48 weeks and evaluated after one full year. The results showed that 15 to 18% of study subjects were completely cured of nail fungus. Daily use of Kerydin resulted in a cure rate for 6.5-9% of study subjects."
Answered by AI
Does Kerydin really work?
"Kerydin and Jublia are only effective in curing nail fungus in a small percentage of patients. The best option for treating onychomycosis is laser removal."
Answered by AI
How long does Kerydin take to work?
"Whenever you are treating fungal toenail infections, you will need to be very patient. This is because it usually takes many months to get rid of fungus and for healthy nails to grow back. Tavaborole (Kerydin) should be used for 48 weeks (over 10 months)."
Answered by AI
Do I need a prescription for Kerydin?
"Kerydin is a prescription medication that is used to treat the symptoms of Onychomycosis of the Toenail. Kerydin may be used by itself or in combination with other medications. Kerydin is classified as an Antifungal, Topical drug."
Answered by AI