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What is Isentress
RaltegravirThe Generic name of this drug
Treatment SummaryRaltegravir is a medication used to treat HIV infections. It was first approved by the FDA in 2007 and is the first drug of its kind, known as an integrase inhibitor. It is produced by Merck & Co. and is used to help control HIV infections.
Isentressis the brand name
Isentress Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Isentress
Raltegravir
2007
20
Approved as Treatment by the FDA
Raltegravir, commonly known as Isentress, is approved by the FDA for 1 uses like HIV .HIV
Used to treat Human Immunodeficiency Virus Type 1 (HIV-1) Infection in combination with null
Effectiveness
How Isentress works in the bodyRaltegravir stops HIV from copying its genetic material into human cells. It is broken down in the body by glucuronidation.
When to interrupt dosage
The advised dosage of Isentress is contingent upon the identified affliction. The sum additionally depends on the technique of delivery specified in the table beneath.Condition
Dosage
Administration
post-exposure prophylaxis for occupational exposure to HIV therapy
400.0 mg, , 300.0 mg, 25.0 mg, 100.0 mg, 600.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, chewable, Tablet, chewable - Oral, Granule, for suspension, Granule, for suspension - Oral, Tablet, Tablet - Oral, Granule, Granule - Oral
HIV
400.0 mg, , 300.0 mg, 25.0 mg, 100.0 mg, 600.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, chewable, Tablet, chewable - Oral, Granule, for suspension, Granule, for suspension - Oral, Tablet, Tablet - Oral, Granule, Granule - Oral
Warnings
Isentress ContraindicationsCondition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Common Isentress Drug Interactions
Drug Name
Risk Level
Description
Atorvastatin
Minor
The risk or severity of myopathy and rhabdomyolysis can be increased when Raltegravir is combined with Atorvastatin.
Cerivastatin
Minor
The risk or severity of myopathy and rhabdomyolysis can be increased when Raltegravir is combined with Cerivastatin.
Fluvastatin
Minor
The risk or severity of myopathy and rhabdomyolysis can be increased when Raltegravir is combined with Fluvastatin.
Lovastatin
Minor
The risk or severity of myopathy and rhabdomyolysis can be increased when Raltegravir is combined with Lovastatin.
Mevastatin
Minor
The risk or severity of myopathy and rhabdomyolysis can be increased when Raltegravir is combined with Mevastatin.
Isentress Novel Uses: Which Conditions Have a Clinical Trial Featuring Isentress?
43 active trials are examining the potential of Isentress to provide treatment for HIV (Human Immunodeficiency Virus).Condition
Clinical Trials
Trial Phases
HIV
38 Actively Recruiting
Phase 2, Phase 3, Early Phase 1, Not Applicable, Phase 1, Phase 4
post-exposure prophylaxis for occupational exposure to HIV therapy
0 Actively Recruiting
Isentress Reviews: What are patients saying about Isentress?
5Patient Review
10/1/2011 I've been on this treatment for two years and it has done a great job of keeping my virus undetectable. My CD4 count is slowly rising, which is encouraging. I do still have some trouble sleeping, but that's manageable.
5Patient Review
7/21/2013 So far, I've had zero side effects from taking Truvada and Isentress. This is my first experience with HIV medication, so I'm cautiously optimistic. I'll update this review when I have more information.
5Patient Review
10/6/2010 I began to experience some adverse effects after a couple of months on this medication. They included difficulty sleeping, dizziness, and severe joint pain in my knees which also radiated to my lower back.
5Patient Review
6/16/2011 I was feeling really weak and depressed before I started this treatment, but it's helped me a lot. I'm not as annoyed with everything, either.
5Patient Review
7/2/2013 So far the medication has been effective and the virus is no longer detectable.
Patient Q&A Section about isentress
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is Isentress used for?
"This text is discussing ISENTRESS, a prescription medication used to treat HIV-1 infection in both adults and children. The medication is taken with other antiretroviral medicines, and is safe for children weighing at least 4.4 pounds."
Answered by AI
What type of drug is Isentress?
"Isentress is a medication used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). It belongs to a group of antiretroviral drugs that prevent the virus from multiplying in your body. Raltegravir is not a cure for HIV or AIDS."
Answered by AI
How long do you take Isentress for?
"You should take Isentress for 28 days if you are taking it as part of your PEP regimen. If you are taking Isentress as part of your HIV regimen, you should continue taking it until your healthcare provider tells you to stop."
Answered by AI
Do you have to take Truvada and Isentress together?
"It's important to take Isentress at the same time every day. You can take it with or without food. If you're also taking Truvada, you can take them at the same time."
Answered by AI
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