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What is Icosapent Ethyl
Icosapent ethylThe Generic name of this drug
Treatment SummaryIcosapent ethyl is a synthetic form of the omega-3 fatty acid eicosapentaenoic acid (EPA). It is used as an additional treatment for very high levels of triglycerides (TG) in the blood (greater than 500 milligrams per deciliter). The FDA approved it in 2012.
Vascepais the brand name
Icosapent Ethyl Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Vascepa
Icosapent ethyl
2012
14
Approved as Treatment by the FDA
Icosapent ethyl, otherwise known as Vascepa, is approved by the FDA for 6 uses such as Hospitalizations and Cardiovascular Disease .Hospitalizations
Cardiovascular Disease
Diabetes
Cardiovascular Diseases
Cardiovascular Events
elevation of serum triglyceride levels
Effectiveness
How Icosapent Ethyl works in the bodyEPA helps to reduce triglyceride levels by increasing fat burning, stopping fat production in the liver, and boosting the activity of a protein that helps break down triglycerides. These effects work together to help lower the amount of triglycerides in the body.
When to interrupt dosage
The allotment of Icosapent Ethyl is contingent upon the diagnosed condition. The dose likewise depends on the technique of administration specified in the table below.Condition
Dosage
Administration
Cardiovascular Diseases
, 1000.0 mg, 500.0 mg, 0.625 mg, 998.0 mg
, Oral, Capsule, Capsule - Oral, Tablet, coated - Oral, Tablet, coated
Cardiovascular Events
, 1000.0 mg, 500.0 mg, 0.625 mg, 998.0 mg
, Oral, Capsule, Capsule - Oral, Tablet, coated - Oral, Tablet, coated
Hospitalizations
, 1000.0 mg, 500.0 mg, 0.625 mg, 998.0 mg
, Oral, Capsule, Capsule - Oral, Tablet, coated - Oral, Tablet, coated
Diet
, 1000.0 mg, 500.0 mg, 0.625 mg, 998.0 mg
, Oral, Capsule, Capsule - Oral, Tablet, coated - Oral, Tablet, coated
elevation of serum triglyceride levels
, 1000.0 mg, 500.0 mg, 0.625 mg, 998.0 mg
, Oral, Capsule, Capsule - Oral, Tablet, coated - Oral, Tablet, coated
Cardiovascular Disease
, 1000.0 mg, 500.0 mg, 0.625 mg, 998.0 mg
, Oral, Capsule, Capsule - Oral, Tablet, coated - Oral, Tablet, coated
Diabetes
, 1000.0 mg, 500.0 mg, 0.625 mg, 998.0 mg
, Oral, Capsule, Capsule - Oral, Tablet, coated - Oral, Tablet, coated
Warnings
Icosapent Ethyl has one contraindication, thus it should not be employed for any of the ailments listed in the subsequent table.Icosapent Ethyl ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Icosapent Ethyl may interact with Pulse Frequency
Common Icosapent Ethyl Drug Interactions
Drug Name
Risk Level
Description
Abrocitinib
Major
The risk or severity of bleeding and thrombocytopenia can be increased when Icosapent ethyl is combined with Abrocitinib.
Aldesleukin
Minor
The risk or severity of bleeding can be increased when Icosapent ethyl is combined with Aldesleukin.
Alemtuzumab
Minor
The risk or severity of bleeding can be increased when Icosapent ethyl is combined with Alemtuzumab.
Altretamine
Minor
The risk or severity of bleeding can be increased when Icosapent ethyl is combined with Altretamine.
Amsacrine
Minor
The risk or severity of bleeding can be increased when Icosapent ethyl is combined with Amsacrine.
Icosapent Ethyl Toxicity & Overdose RiskIcosapent ethyl is generally safe and any reported side effects are not related to taking the drug.
Icosapent Ethyl Novel Uses: Which Conditions Have a Clinical Trial Featuring Icosapent Ethyl?
Four investigations are currently analyzing the potential of Icosapent Ethyl to mitigate Hypertriglyceridemia.Condition
Clinical Trials
Trial Phases
Cardiovascular Disease
30 Actively Recruiting
Not Applicable, Phase 1, Early Phase 1, Phase 3, Phase 2
Hospitalizations
2 Actively Recruiting
Not Applicable
elevation of serum triglyceride levels
2 Actively Recruiting
Not Applicable
Diet
5 Actively Recruiting
Not Applicable
Cardiovascular Events
3 Actively Recruiting
Not Applicable
Cardiovascular Diseases
0 Actively Recruiting
Diabetes
542 Actively Recruiting
Phase 2, Phase 1, Phase 3, Not Applicable, Phase 4, Early Phase 1
Icosapent Ethyl Reviews: What are patients saying about Icosapent Ethyl?
5Patient Review
7/13/2018 I'm really pleased with this medication. I saw a significant reduction in my triglyceride levels within six months of taking two capsules twice daily.
4.3Patient Review
2/27/2017 I take two 1gm capsules twice daily during meals and it lowered my triglyceride levels by 1/3 . Only side effect was wrist joint pain that eventually went away. Highly recommend it, even though it can be quite expensive without insurance.
Patient Q&A Section about icosapent ethyl
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is icosapent ethyl the same as fish oil?
"Vascepa (icosapent ethyl) is a prescription omega-3 fatty acid. It is similar to fish oil, but not exactly the same."
Answered by AI
What is icosapent ethyl prescribed for?
"Icosapent ethyl is a drug used to control high triglyceride levels in the blood when taken with a proper diet."
Answered by AI
Is icosapent ethyl good for you?
"When taken together with a statin, Vascepa (icosapent ethyl) can help protect the heart of certain people who are at high risk of heart disease by lowering their triglyceride levels."
Answered by AI
What is the difference between Vascepa and icosapent ethyl?
"Omega-3-acid ethyl esters, also known by its brand name Lovaza, is a medication taken in the form of a capsule that is swallowed. It is taken either once or twice a day. Another medication, Vascepa, which is also a formulation of omega-3 fatty acids derived from fish oil, is taken in the same way, but twice a day."
Answered by AI