What is Hydrocortisone Butyrate
Hydrocortisone butyrateThe Generic name of this drug
Hydrocortisone Butyrateis the brand name
Hydrocortisone Butyrate Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Hydrocortisone Butyrate
Hydrocortisone butyrate
1987
34
Approved as Treatment by the FDA
Hydrocortisone butyrate, also known as Hydrocortisone Butyrate, is approved by the FDA for 3 uses like Pruritus and Pruritus .Pruritus
Pruritus
corticosteroid responsive, Inflammatory Dermatosis
Effectiveness
How Hydrocortisone Butyrate Affects PatientsHydrocortisone is a steroid hormone that helps regulate important body functions like blood pressure, metabolism, and immunity. It is applied to the skin to reduce inflammation and itching caused by skin conditions. Glucocorticoids like hydrocortisone work by suppressing the production of cytokines, which are chemicals involved in the immune response. This reduces the expansion of B cells and T cells, resulting in fewer activated T lymphocyte cells.
How Hydrocortisone Butyrate works in the bodyHydrocortisone works by binding to receptors in the cell nucleus and increasing the expression of certain genes. It also prevents chemical compounds called eicosanoids from being produced. These compounds are involved in inflammation, and when they are prevented from forming, inflammation decreases. Hydrocortisone also suppresses the immune system by reducing the function of the lymphatic system, lowering immunoglobulin and complement concentrations, and reducing lymphocytes. This helps prevent the body from overreacting to allergens and other sources of inflammation.
When to interrupt dosage
The advocated dose of Hydrocortisone Butyrate is contingent upon the diagnosed condition, such as Atopic Dermatitis, Pruritus and corticosteroid responsive, Inflammatory Dermatosis. The quantity also depends on the delivery system (e.g. Cream or Patch - Cutaneous) featured in the following table.Condition
Dosage
Administration
Atopic Dermatitis
0.0016 mg/hour, 0.003 mg/mg, , 0.00003 mg/mg, 0.001 mg/mg, 1.0 mg/mL
Cream, Patch - Cutaneous, Cutaneous, Topical, , Ointment, Solution - Topical, Kit, Ointment - Topical, Cream - Topical, Patch, Solution, Lotion - Topical, Kit - Cutaneous, Lotion
Pruritus
0.0016 mg/hour, 0.003 mg/mg, , 0.00003 mg/mg, 0.001 mg/mg, 1.0 mg/mL
Cream, Patch - Cutaneous, Cutaneous, Topical, , Ointment, Solution - Topical, Kit, Ointment - Topical, Cream - Topical, Patch, Solution, Lotion - Topical, Kit - Cutaneous, Lotion
corticosteroid responsive, Inflammatory Dermatosis
0.0016 mg/hour, 0.003 mg/mg, , 0.00003 mg/mg, 0.001 mg/mg, 1.0 mg/mL
Cream, Patch - Cutaneous, Cutaneous, Topical, , Ointment, Solution - Topical, Kit, Ointment - Topical, Cream - Topical, Patch, Solution, Lotion - Topical, Kit - Cutaneous, Lotion
Pruritus
0.0016 mg/hour, 0.003 mg/mg, , 0.00003 mg/mg, 0.001 mg/mg, 1.0 mg/mL
Cream, Patch - Cutaneous, Cutaneous, Topical, , Ointment, Solution - Topical, Kit, Ointment - Topical, Cream - Topical, Patch, Solution, Lotion - Topical, Kit - Cutaneous, Lotion
Warnings
There are 20 known major drug interactions with Hydrocortisone Butyrate.Common Hydrocortisone Butyrate Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The metabolism of Abemaciclib can be increased when combined with Hydrocortisone butyrate.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be increased when combined with Hydrocortisone butyrate.
Alectinib
Major
The metabolism of Alectinib can be increased when combined with Hydrocortisone butyrate.
Alpelisib
Major
The metabolism of Alpelisib can be increased when combined with Hydrocortisone butyrate.
Aminophylline
Major
The metabolism of Aminophylline can be increased when combined with Hydrocortisone butyrate.
Hydrocortisone Butyrate Toxicity & Overdose RiskTaking too much of this drug can lead to problems with bone growth, decreased calcium absorption, and slower healing of wounds.
Hydrocortisone Butyrate Novel Uses: Which Conditions Have a Clinical Trial Featuring Hydrocortisone Butyrate?
67 active trials are currently assessing the potential of Hydrocortisone Butyrate for providing relief from Atopic Dermatitis, Pruritus and corticosteroid responsive Inflammatory Dermatoses.Condition
Clinical Trials
Trial Phases
Atopic Dermatitis
75 Actively Recruiting
Phase 3, Phase 4, Not Applicable, Phase 1, Phase 2, Early Phase 1
Pruritus
0 Actively Recruiting
corticosteroid responsive, Inflammatory Dermatosis
0 Actively Recruiting
Pruritus
0 Actively Recruiting
Hydrocortisone Butyrate Reviews: What are patients saying about Hydrocortisone Butyrate?
5Patient Review
3/1/2013 I applied hydrocortisone butyrate 0.1% to my baby's severe cradle cap and it worked wonders.
4.7Patient Review
3/9/2012 I've been using this cream around my eyes, per doctor's directions, and it has completely stopped the itchiness I was experiencing. Two days in and no more swelling or crusting, either.
4.3Patient Review
8/11/2010 It's working well, although it took slightly longer to take effect than I was expecting. That said, I didn't exactly ask my doctor how long it would take, so my expectations might not have been realistic in the first place.
4.3Patient Review
6/10/2010 I've used this for two days now, and the rash on my hand has already cleared up significantly. I'll continue using it for a few more days to be safe, but so far I'm really happy with the results.
3.7Patient Review
2/10/2015 This helps when my nose and ears turn red from an autoimmune skin condition, but the effect only lasts for about two weeks. I need to use it once every four weeks or so to prevent a bright red nose. Not sure how long my nose can take this kind of treatment, but we'll see.
2Patient Review
12/1/20091Patient Review
5/6/2010 I had a really terrible experience using this. If you're allergic to steroids, please ask your doctor first. I'm now on a long course of antibiotics because this medicine caused me to have a severe reaction.
Patient Q&A Section about hydrocortisone butyrate
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is hydrocortisone butyrate the same as hydrocortisone?
"It is important not to confuse hydrocortisone butyrate preparations with creams and ointments called 'hydrocortisone'. These are milder topical steroid preparations available from pharmacies. Hydrocortisone butyrate is a much more potent steroid only available on prescription."
Answered by AI
Can you put hydrocortisone butyrate on your face?
"Apply a small amount of medication to the area and rub in gently.
This medication is meant to be used on the skin only. However, do not use it on the face, groin, or underarms, unless your doctor says it is okay. To use the medication, wash and dry your hands first. Next, clean and dry the affected area. Finally, apply a small amount of medication to the area and rub it in gently."
Answered by AI
What is hydrocortisone butyrate used for?
"Hydrocortisone butyrate topical is a corticosteroid that is used to relieve redness, itching, swelling, or other discomfort caused by skin conditions such as atopic dermatitis or seborrheic dermatitis."
Answered by AI
Is hydrocortisone cream an emollient?
"To use hydrocortisone-emollient:
Apply a small amount of the lotion or cream to the affected area.
Rub it in until it is absorbed.
Do not apply hydrocortisone to broken skin.
To use the kit:
Clean the affected area with the cleansing pad.
Do not scrub.
Apply a small amount of the lotion or cream to the affected area.
Rub it in until it is absorbed.
Throw away the used pad.
There are many hydrocortisone products available. Many can be purchased without a prescription.
To use hydrocortisone-emollient:
Apply a small amount of the lotion or cream to the affected area.
Rub it in until it is absorbed.
Do not apply hydrocortisone to broken skin.
To use the kit:
Clean the affected area with the cleansing pad.
Do not scrub.
Apply a small amount of the lotion or cream to the affected area.
Rub it in until it is absorbed.
Throw away the used pad."
Answered by AI