Grifulvin V

Tinea Pedis, Tinea barbae, Kerion Celsi + 3 more

Treatment

11 FDA approvals

0 Active Studies for Grifulvin V

What is Grifulvin V

Griseofulvin

The Generic name of this drug

Treatment Summary

Griseofulvin is an antibiotic used to treat fungal infections such as tinea. It is taken orally.

Griseofulvin MICROSIZE

is the brand name

image of different drug pills on a surface

Grifulvin V Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Griseofulvin MICROSIZE

Griseofulvin

1971

41

Approved as Treatment by the FDA

Griseofulvin, otherwise known as Griseofulvin MICROSIZE, is approved by the FDA for 11 uses including Tinea Cruris and Tinea Corporis .

Tinea Cruris

Tinea Corporis

Tinea Unguium

Tinea Capitis

Tinea Pedis

Tinea barbae

Tinea Cruris

Kerion Celsi

Onychomycosis

Foot

Tinea

Effectiveness

How Grifulvin V Affects Patients

Griseofulvin is a medication made from a type of mold. It is used to treat fungal infections on the skin, and has been used for over forty years. After being taken orally, Griseofulvin is deposited in the cells that create skin and hair, and has a stronger affinity for infected areas. It binds to the newly created cells, which makes them resistant to fungal invasions. Once it reaches the affected area, it binds to the fungal microtubules and changes the way the fungus grows.

How Grifulvin V works in the body

Griseofulvin works to stop the growth of fungi. It does this by stopping the cell division process in fungi and disrupting the production of new molecules. Griseofulvin also binds to certain proteins in fungal cells, which prevents them from forming the structures needed for successful cell division. Finally, it binds to keratin in human cells, which helps it reach the fungi and then binds to the fungal cells, further disrupting the cell division process.

When to interrupt dosage

The measure of Grifulvin V is predicated upon the determined condition, including Tinea cruris, Tinea barbae and Tinea Unguium. The magnitude of dosage relies upon the system of delivery as specified in the table below.

Condition

Dosage

Administration

Tinea barbae

, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg

, Oral, Tablet - Oral, Tablet, Suspension - Oral, Suspension, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, film coated

Kerion Celsi

, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg

, Oral, Tablet - Oral, Tablet, Suspension - Oral, Suspension, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, film coated

Tinea Cruris

, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg

, Oral, Tablet - Oral, Tablet, Suspension - Oral, Suspension, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, film coated

Tinea Pedis

, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg

, Oral, Tablet - Oral, Tablet, Suspension - Oral, Suspension, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, film coated

Tinea

, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg

, Oral, Tablet - Oral, Tablet, Suspension - Oral, Suspension, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, film coated

Onychomycosis

, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg

, Oral, Tablet - Oral, Tablet, Suspension - Oral, Suspension, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, film coated

Warnings

Grifulvin V Contraindications

Condition

Risk Level

Notes

Porphyrias

Do Not Combine

Liver Failure

Do Not Combine

There are 20 known major drug interactions with Grifulvin V.

Common Grifulvin V Drug Interactions

Drug Name

Risk Level

Description

Abemaciclib

Major

The metabolism of Abemaciclib can be increased when combined with Griseofulvin.

Acalabrutinib

Major

The metabolism of Acalabrutinib can be increased when combined with Griseofulvin.

Alectinib

Major

The metabolism of Alectinib can be increased when combined with Griseofulvin.

Alpelisib

Major

The metabolism of Alpelisib can be increased when combined with Griseofulvin.

Aminophylline

Major

The metabolism of Aminophylline can be increased when combined with Griseofulvin.

Grifulvin V Toxicity & Overdose Risk

Common side effects from taking this drug are headaches, digestive issues, and skin rashes.

image of a doctor in a lab doing drug, clinical research

Grifulvin V Novel Uses: Which Conditions Have a Clinical Trial Featuring Grifulvin V?

Currently, there are no active studies examining the potential of Grifulvin V in treating Tinea Corporis, Tinea barbae and Tinea Pedis.

Condition

Clinical Trials

Trial Phases

Tinea Pedis

0 Actively Recruiting

Tinea barbae

0 Actively Recruiting

Tinea

0 Actively Recruiting

Onychomycosis

0 Actively Recruiting

Tinea Cruris

0 Actively Recruiting

Kerion Celsi

0 Actively Recruiting

Grifulvin V Reviews: What are patients saying about Grifulvin V?

5

Patient Review

7/10/2013

Grifulvin V for Ringworm of Scalp

These oral tabs have been working great for me. I've only been taking them for a few days, but the ringworm is already starting to clear up.

5

Patient Review

12/30/2012

Grifulvin V for Ringworm of Scalp

I've used this medicine before and it worked great, so I had no hesitation using it again when my child got ringworm.

4.7

Patient Review

8/28/2009

Grifulvin V for Fungal Infection of Fingernails - Onychomycosis

For the first week I had incredibly severe headaches and stomach aches. The doctor neglected to mention that this drug would make me dizzy. After taking for the first week, the ringworm started itching horribly worse than it ever had before. Even though it's drying up now, when I put anti itch cream on it burns very badly for about 20 minutes before the itchiness goes away.

4

Patient Review

9/10/2010

Grifulvin V for Ringworm of Groin Area

I took this medication once a day for five weeks, and it cleared up an infection as well as some nail fungus on my toes.

3.7

Patient Review

12/10/2009

Grifulvin V for Ringworm of the Body

My twelve year old daughter has had ringworm for a year now. I've tried every topical cream there is. She started with the liquid Griseofulvin 10 days ago. (300mg 2x's a day for 8 weeks) Haven't noticed any change in ringworm, but no side effects either which is good. Will continue to update on progress.

3.7

Patient Review

1/20/2010

Grifulvin V for Ringworm of the Body

I saw results from this medication overnight, which was amazing. However, after about a week of use my gout flared up again. I stopped taking the medication and the pain went away, so I'm not sure if it's worth the risk for me.

3.7

Patient Review

2/4/2009

Grifulvin V for Ringworm of the Body

I had a severe headache all weekend after taking the first dosage on Thursday.

3

Patient Review

5/5/2011

Grifulvin V for Ringworm of the Body

While this medication did help get rid of my ringworm, I constantly felt tired and it took a toll on my work and family life.

2.3

Patient Review

1/11/2009

Grifulvin V for Ringworm of Scalp

2

Patient Review

2/22/2009

Grifulvin V for Ringworm of the Body

I was disappointed that there wasn't a warning about sun sensitivity on the label. I got seriously sunburned as a result of using this treatment and it still hasn't completely gone away even though it's been weeks.

2

Patient Review

9/8/2009

Grifulvin V for Ringworm of Scalp

I've been taking this for about a month now. Prior to starting the medication, I would get one nail infection at a time. Since starting it, though, I haven't had any new infections. Now I'm just waiting to see if it will improve the nails that were already infected.

1.7

Patient Review

4/10/2010

Grifulvin V for Ringworm of the Body

I took this medication for only two days because the side effects were so severe. I had a terrible headache, felt nauseous, and my stomach hurt terribly. Do not recommend this medicine to anyone.

1

Patient Review

9/22/2009

Grifulvin V for Ringworm of the Body

There was very little improvement after taking this drug for a month. I experienced severe headaches, loss of appetite, severe stomach aches, and extreme itchiness in the affected area. Additionally, the cost for 30 pills was $155.

1

Patient Review

11/3/2009

Grifulvin V for Ringworm of the Body

I tried soaking in a bath of epsom salts before taking any medication for ringworm and it worked like a charm.

1

Patient Review

3/10/2010

Grifulvin V for Ringworm of the Body

I was extremely disappointed with this treatment. I had a few ringworms and saw no change after completing the prescribed dosage. The only thing that changed were some bothersome side effects like headaches, insomnia, and a sore tongue.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about grifulvin v

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is griseofulvin an antibiotic?

"A new oral antibiotic, griseofulvin, has been found to be effective in treating fungal infections of the skin. This new medication is taken in pill form and is well tolerated by most patients. It is especially useful in treating children with fungal infections of the scalp and nails."

Answered by AI

What is grifulvin V used for?

"This medication is used to treat fungal infections of the skin, hair, and nails. Clearing such infections will get rid of symptoms such as itching, red/peeling/scaly skin, and discolored nails. This medication works by inhibiting the growth of fungi."

Answered by AI

What is the most common side effect of griseofulvin?

"Some side effects that might occur are: headaches, feeling nauseous, vomiting, having diarrhea, stomachaches, feeling tired, dizzy, or having trouble sleeping."

Answered by AI

How long does griseofulvin take to work?

"Typically, it takes two to four weeks for skin infections, three to four months for fingernail infections, and at least six months for toenail infections to heal. You should continue taking this medicine for as long as your doctor tells you to."

Answered by AI