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What is Grifulvin V
GriseofulvinThe Generic name of this drug
Treatment SummaryGriseofulvin is an antibiotic used to treat fungal infections such as tinea. It is taken orally.
Griseofulvin MICROSIZEis the brand name
Grifulvin V Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Griseofulvin MICROSIZE
Griseofulvin
1971
41
Approved as Treatment by the FDA
Griseofulvin, otherwise known as Griseofulvin MICROSIZE, is approved by the FDA for 6 uses including Tinea Corporis and Tinea Pedis .Tinea Corporis
Tinea Pedis
Kerion Celsi
Tinea barbae
Tinea Unguium
Tinea cruris
Effectiveness
How Grifulvin V Affects PatientsGriseofulvin is a medication made from a type of mold. It is used to treat fungal infections on the skin, and has been used for over forty years. After being taken orally, Griseofulvin is deposited in the cells that create skin and hair, and has a stronger affinity for infected areas. It binds to the newly created cells, which makes them resistant to fungal invasions. Once it reaches the affected area, it binds to the fungal microtubules and changes the way the fungus grows.
How Grifulvin V works in the bodyGriseofulvin works to stop the growth of fungi. It does this by stopping the cell division process in fungi and disrupting the production of new molecules. Griseofulvin also binds to certain proteins in fungal cells, which prevents them from forming the structures needed for successful cell division. Finally, it binds to keratin in human cells, which helps it reach the fungi and then binds to the fungal cells, further disrupting the cell division process.
When to interrupt dosage
The measure of Grifulvin V is predicated upon the determined condition, including Tinea cruris, Tinea barbae and Tinea Unguium. The magnitude of dosage relies upon the system of delivery as specified in the table below.Condition
Dosage
Administration
Tinea cruris
, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg
, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral
Tinea Pedis
, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg
, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral
Tinea Corporis
, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg
, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral
Tinea barbae
, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg
, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral
Tinea Unguium
, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg
, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral
Kerion Celsi
, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg
, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral
Warnings
Grifulvin V ContraindicationsCondition
Risk Level
Notes
Porphyria
Do Not Combine
hepatocellular failure
Do Not Combine
Common Grifulvin V Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The metabolism of Abemaciclib can be increased when combined with Griseofulvin.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be increased when combined with Griseofulvin.
Alectinib
Major
The metabolism of Alectinib can be increased when combined with Griseofulvin.
Alpelisib
Major
The metabolism of Alpelisib can be increased when combined with Griseofulvin.
Aminophylline
Major
The metabolism of Aminophylline can be increased when combined with Griseofulvin.
Grifulvin V Toxicity & Overdose RiskCommon side effects from taking this drug are headaches, digestive issues, and skin rashes.
Grifulvin V Novel Uses: Which Conditions Have a Clinical Trial Featuring Grifulvin V?
Currently, there are no active studies examining the potential of Grifulvin V in treating Tinea Corporis, Tinea barbae and Tinea Pedis.Condition
Clinical Trials
Trial Phases
Tinea Pedis
0 Actively Recruiting
Tinea Corporis
0 Actively Recruiting
Tinea barbae
0 Actively Recruiting
Tinea Unguium
0 Actively Recruiting
Tinea cruris
0 Actively Recruiting
Kerion Celsi
0 Actively Recruiting
Grifulvin V Reviews: What are patients saying about Grifulvin V?
5Patient Review
7/10/2013 These oral tabs have been working great for me. I've only been taking them for a few days, but the ringworm is already starting to clear up.
5Patient Review
12/30/2012 I've used this medicine before and it worked great, so I had no hesitation using it again when my child got ringworm.
4.7Patient Review
8/28/2009 For the first week I had incredibly severe headaches and stomach aches. The doctor neglected to mention that this drug would make me dizzy. After taking for the first week, the ringworm started itching horribly worse than it ever had before. Even though it's drying up now, when I put anti itch cream on it burns very badly for about 20 minutes before the itchiness goes away.
4Patient Review
9/10/2010 I took this medication once a day for five weeks, and it cleared up an infection as well as some nail fungus on my toes.
3.7Patient Review
12/10/2009 My twelve year old daughter has had ringworm for a year now. I've tried every topical cream there is. She started with the liquid Griseofulvin 10 days ago. (300mg 2x's a day for 8 weeks) Haven't noticed any change in ringworm, but no side effects either which is good. Will continue to update on progress.
3.7Patient Review
1/20/2010 I saw results from this medication overnight, which was amazing. However, after about a week of use my gout flared up again. I stopped taking the medication and the pain went away, so I'm not sure if it's worth the risk for me.
3.7Patient Review
2/4/2009 I had a severe headache all weekend after taking the first dosage on Thursday.
3Patient Review
5/5/2011 While this medication did help get rid of my ringworm, I constantly felt tired and it took a toll on my work and family life.
2.3Patient Review
1/11/20092Patient Review
2/22/2009 I was disappointed that there wasn't a warning about sun sensitivity on the label. I got seriously sunburned as a result of using this treatment and it still hasn't completely gone away even though it's been weeks.
2Patient Review
9/8/2009 I've been taking this for about a month now. Prior to starting the medication, I would get one nail infection at a time. Since starting it, though, I haven't had any new infections. Now I'm just waiting to see if it will improve the nails that were already infected.
1.7Patient Review
4/10/2010 I took this medication for only two days because the side effects were so severe. I had a terrible headache, felt nauseous, and my stomach hurt terribly. Do not recommend this medicine to anyone.
1Patient Review
9/22/2009 There was very little improvement after taking this drug for a month. I experienced severe headaches, loss of appetite, severe stomach aches, and extreme itchiness in the affected area. Additionally, the cost for 30 pills was $155.
1Patient Review
11/3/2009 I tried soaking in a bath of epsom salts before taking any medication for ringworm and it worked like a charm.
1Patient Review
3/10/2010 I was extremely disappointed with this treatment. I had a few ringworms and saw no change after completing the prescribed dosage. The only thing that changed were some bothersome side effects like headaches, insomnia, and a sore tongue.
Patient Q&A Section about grifulvin v
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is griseofulvin an antibiotic?
"A new oral antibiotic, griseofulvin, has been found to be effective in treating fungal infections of the skin. This new medication is taken in pill form and is well tolerated by most patients. It is especially useful in treating children with fungal infections of the scalp and nails."
Answered by AI
What is grifulvin V used for?
"This medication is used to treat fungal infections of the skin, hair, and nails. Clearing such infections will get rid of symptoms such as itching, red/peeling/scaly skin, and discolored nails. This medication works by inhibiting the growth of fungi."
Answered by AI
What is the most common side effect of griseofulvin?
"Some side effects that might occur are: headaches, feeling nauseous, vomiting, having diarrhea, stomachaches, feeling tired, dizzy, or having trouble sleeping."
Answered by AI
How long does griseofulvin take to work?
"Typically, it takes two to four weeks for skin infections, three to four months for fingernail infections, and at least six months for toenail infections to heal. You should continue taking this medicine for as long as your doctor tells you to."
Answered by AI