Benzoyl peroxide for Molluscum Contagiosum

Phase-Based Progress Estimates
2
Effectiveness
3
Safety
OU Health Department of Dermatology, Oklahoma City, OK
Molluscum Contagiosum
Benzoyl peroxide - Drug
Eligibility
< 18
All Sexes
What conditions do you have?
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Study Summary

Non-blinded randomized controlled trial comparing efficacy of topical benzoyl peroxide 10% (vehicle choice per patient preference: e.g. gel, cream, lotion, wash) to topical adapalene 0.1% gel in the treatment of molluscum contagiosum in children aged 1 year old to 14 years old. Two treatment wings: topical benzoyl peroxide 10% (vehicle choice per patient preference) applied 1-2x daily as tolerated vs adapalene 0.1% gel applied 1-2x daily as tolerated. Primary outcome: Complete clearance at 12wks (defined as lack of identifiable papular molluscum contagiosum lesions on physical exam) Secondary outcomes: % change in lesion count at 12wks.

Treatment Effectiveness

Effectiveness Progress

2 of 3
This is further along than 85% of similar trials

Other trials for Molluscum Contagiosum

Study Objectives

1 Primary · 1 Secondary · Reporting Duration: 12 weeks

12 weeks
% change in lesion count at 12 weeks
Complete clearance at 12 weeks
Incidence and severity of irritant contact dermatitis and other adverse events

Trial Safety

Safety Progress

3 of 3
This is further along than 85% of similar trials

Other trials for Molluscum Contagiosum

Trial Design

2 Treatment Groups

Adapalene
1 of 2
Benzoyl peroxide
1 of 2
Active Control
Experimental Treatment

150 Total Participants · 2 Treatment Groups

Primary Treatment: Benzoyl peroxide · No Placebo Group · Phase 3

Benzoyl peroxide
Drug
Experimental Group · 1 Intervention: Benzoyl peroxide · Intervention Types: Drug
Adapalene
Drug
ActiveComparator Group · 1 Intervention: Adapalene Gel · Intervention Types: Drug
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Benzoyl peroxide
2006
Completed Phase 3
~2820

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 12 weeks
Closest Location: OU Health Department of Dermatology · Oklahoma City, OK
Photo of oklahoma city  1Photo of oklahoma city  2Photo of oklahoma city  3
N/AFirst Recorded Clinical Trial
1 TrialsResearching Molluscum Contagiosum
0 CompletedClinical Trials

Eligibility Criteria

Age < 18 · All Participants · 1 Total Inclusion Criteria

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About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.

References