What is Genvoya
ElvitegravirThe Generic name of this drug
Treatment SummaryElvitegravir is a medication used to treat HIV-1 infections in adults who have already tried other antiretroviral treatments. It works by stopping the virus from replicating and spreading. Elvitegravir must be taken in combination with other medications, including an HIV protease inhibitor, ritonavir, and another antiretroviral drug. It was first licensed in 2008 and approved by the FDA in 2012. In 2014, the single pill form of elvitegravir was approved.
Stribildis the brand name
Genvoya Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Stribild
Elvitegravir
2012
10
Approved as Treatment by the FDA
Elvitegravir, also known as Stribild, is approved by the FDA for 2 uses which include HIV and treatment experienced .HIV
treatment experienced
Effectiveness
How Genvoya works in the bodyElvitegravir is an anti-HIV drug that stops the virus from replicating. It does this by blocking the enzyme called integrase, which is needed for HIV-1 to spread. Elvitegravir does not affect the host's own topoisomerases, which are enzymes involved in DNA regulation.
When to interrupt dosage
The proposed measure of Genvoya is contingent upon the perceived condition, including treatment experienced, Treatment Naive and HIV (Human Immunodeficiency Virus). The amount of dosage relies upon the technique of delivery (e.g. Tablet, film coated or Tablet) delineated in the table hereunder.Condition
Dosage
Administration
treatment experienced
, 150.0 mg, 85.0 mg
Tablet, film coated, Tablet, , Tablet, film coated - Oral, Tablet - Oral, Oral
Treatment Naive
, 150.0 mg, 85.0 mg
Tablet, film coated, Tablet, , Tablet, film coated - Oral, Tablet - Oral, Oral
HIV
, 150.0 mg, 85.0 mg
Tablet, film coated, Tablet, , Tablet, film coated - Oral, Tablet - Oral, Oral
Warnings
Genvoya ContraindicationsCondition
Risk Level
Notes
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Common Genvoya Drug Interactions
Drug Name
Risk Level
Description
1,2-Benzodiazepine
Major
The metabolism of 1,2-Benzodiazepine can be decreased when combined with Elvitegravir.
3,5-diiodothyropropionic acid
Major
The metabolism of 3,5-diiodothyropropionic acid can be decreased when combined with Elvitegravir.
5-androstenedione
Major
The metabolism of 5-androstenedione can be decreased when combined with Elvitegravir.
6-O-benzylguanine
Major
The metabolism of 6-O-benzylguanine can be decreased when combined with Elvitegravir.
7-ethyl-10-hydroxycamptothecin
Major
The metabolism of 7-ethyl-10-hydroxycamptothecin can be decreased when combined with Elvitegravir.
Genvoya Toxicity & Overdose RiskTaking elvitegravir may lead to nausea, vomiting, diarrhea, abdominal pain, indigestion, fatigue, insomnia, rash, depression, and suicidal thoughts or attempts. These side effects are not very common and occur in fewer than 2% of patients.
Genvoya Novel Uses: Which Conditions Have a Clinical Trial Featuring Genvoya?
43 active clinical trials are assessing the potential of Genvoya in managing HIV (Human Immunodeficiency Virus) in both Treatment Naive and Treatment Experienced Patients.Condition
Clinical Trials
Trial Phases
HIV
45 Actively Recruiting
Phase 2, Phase 3, Early Phase 1, Phase 1, Phase 4, Not Applicable
Treatment Naive
0 Actively Recruiting
treatment experienced
0 Actively Recruiting
Genvoya Reviews: What are patients saying about Genvoya?
5Patient Review
5/21/2017 I was diagnosed in April 2017 and have been amazed by the progress of my treatment.
5Patient Review
10/18/2016 This treatment is very simple, just one pill a day. I did experience some dizziness, but it was nothing compared to other drugs I've been prescribed.
5Patient Review
12/22/2016 I'm really pleased with genvoya. I started taking it on 8/1/2016 and haven't had a single side effect. In fact, not only did it get rid of a rash I had on my leg, but it did so within a month.
5Patient Review
4/28/2017 I'm pregnant and so far this medication has had zero negative side effects that I can tell.
5Patient Review
12/30/2017 I appreciate that I only have to take this medication once per day, and that there are no side effects. I've been on it for over two years now, and it has helped me immensely.
5Patient Review
7/7/20165Patient Review
8/20/20164.7Patient Review
10/10/2017 I was struggling to sleep, but this treatment really helped me.
4.7Patient Review
7/16/20163.7Patient Review
5/31/2018 I switched to this treatment a month ago and feel much healthier now. I also take an antifungal daily because of spinal meningitis, but my doctor is the best and he saved my life. Recovery was long, but it was worth it in the end.
3.7Patient Review
3/11/2019 I just took my first pill an hour and a half ago. I'm feeling a little tingling in my tongue and cheeks got red, sort of like when someone rubs them. I don't know yet how effective this pill is going to be.
3Patient Review
3/17/2019 I feel like I can't get any good advice on which treatments will work best for me. I was on an old HIV treatment that had been working well for me for 20 years, but the drugs became temporarily unavailable. I was then advised to switch to Genvoya, and started having all kinds of bothersome side effects: fat distribution in my midsection, dryness in my mouth, wake up choking due to lack of moisture, difficulty sleeping.
1Patient Review
6/15/2017 I was diagnosed with HIV in 2014 and have been taking Genvoya for 1.5 years now. I haven't experienced any side effects that I know of, and I'm generally satisfied with the medication.
1Patient Review
6/21/2017 I developed a horrible rash and inflammation after using this treatment.
Patient Q&A Section about genvoya
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Can you drink alcohol while taking Genvoya?
"Most people can drink alcohol while taking Genvoya without any interactions."
Answered by AI
Is Genvoya the same as Biktarvy?
"Genvoya and Biktarvy are both antiretrovirals that contain elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide. Biktarvy also contains bictegravir."
Answered by AI
Does Genvoya make you undetectable?
"In a study of people with HIV-1, those who switched to taking GENVOYA® were 93% more likely to still have an undetectable viral load after two years of treatment, as compared to those who stayed on their current treatment."
Answered by AI
What is Genvoya used to treat?
"Genvoya is a once-daily pill for treating HIV that combines four drugs: 150mg elvitegravir, 200mg emtricitabine, 10mg tenofovir alafenamide, and 150mg cobicistat. The green film-coated tablet bears the markings "GSI" on one side and "510" on the other."
Answered by AI
What are the side effects of Genvoya?
"Some common symptoms of HIV include nausea, diarrhea, fatigue, headaches, and changes in body fat distribution."
Answered by AI