Flumadine

prophylaxis of Influenza A virus infection, influenza A virus
Treatment
2 FDA approvals
4 Active Studies for Flumadine

What is Flumadine

RimantadineThe Generic name of this drug
Treatment SummaryOseltamivir is an antiviral medication used to prevent and treat influenza (the flu). It works by blocking the replication of virus particles in the body.
Flumadineis the brand name
Flumadine Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Flumadine
Rimantadine
1993
11

Approved as Treatment by the FDA

Rimantadine, commonly known as Flumadine, is approved by the FDA for 2 uses which include influenza A virus and prophylaxis of Influenza A virus infection .
influenza A virus
Used to treat Influenza A Virus Infection in combination with Arginine
prophylaxis of Influenza A virus infection

Effectiveness

How Flumadine Affects PatientsRimantadine is a man-made antiviral drug made from a type of chemical called adamantane. It is effective against certain strains of the influenza A virus, but not the influenza B virus. Taking rimantadine does not affect the body's response to the inactivated influenza A vaccine.
How Flumadine works in the bodyWe don't know exactly how rimantadine works, but it seems to prevent the virus from entering cells. It does this by blocking a protein encoded by the M2 gene of influenza A.

When to interrupt dosage

The proposed dose of Flumadine is reliant upon the diagnosed condition. The amount of dosage is contingent upon the technique of delivery listed in the below table.
Condition
Dosage
Administration
influenza A virus
, 100.0 mg, 50.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit, Syrup, Syrup - Oral
prophylaxis of Influenza A virus infection
, 100.0 mg, 50.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit, Syrup, Syrup - Oral

Warnings

There are 12 known major drug interactions with Flumadine.
Common Flumadine Drug Interactions
Drug Name
Risk Level
Description
Adenovirus type 7 vaccine live
Major
The therapeutic efficacy of Adenovirus type 7 vaccine live can be decreased when used in combination with Rimantadine.
Anthrax vaccine
Major
The therapeutic efficacy of Anthrax vaccine can be decreased when used in combination with Rimantadine.
BCG vaccine
Major
The therapeutic efficacy of BCG vaccine can be decreased when used in combination with Rimantadine.
Bacillus calmette-guerin substrain connaught live antigen
Major
The therapeutic efficacy of Bacillus calmette-guerin substrain connaught live antigen can be decreased when used in combination with Rimantadine.
Bacillus calmette-guerin substrain russian BCG-I live antigen
Major
The therapeutic efficacy of Bacillus calmette-guerin substrain russian BCG-I live antigen can be decreased when used in combination with Rimantadine.
Flumadine Toxicity & Overdose RiskThe lowest toxic dose of the drug in rats is 640 mg/kg. Taking too much of a similar medication can cause agitation, hallucinations, irregular heartbeat, and even death.
image of a doctor in a lab doing drug, clinical research

Flumadine Novel Uses: Which Conditions Have a Clinical Trial Featuring Flumadine?

Currently, there are 3 active clinical trials examining the potential of Flumadine in providing relief from influenza A virus.
Condition
Clinical Trials
Trial Phases
influenza A virus
4 Actively Recruiting
Not Applicable
prophylaxis of Influenza A virus infection
0 Actively Recruiting

Flumadine Reviews: What are patients saying about Flumadine?

5Patient Review
10/11/2007
Flumadine for Influenza A Prevention
I've been taking flumadine for seven years now, and it's worked great for me. I only need to take one pill a day instead of the recommended two because I'm sensitive to medications. When I do take it, though, I make sure not to drive as it can make me feel dizzy and disoriented.
1Patient Review
12/28/2012
Flumadine for A Type of Flu - Influenza A
About a decade ago, I took this medication along with a Z-pak and had a severe allergic reaction. Hives, swelling of the throat, crossed eyes for months afterwards... it was awful. Thankfully I've never had an allergic reaction like that since, but I definitely think this drug is dangerous and not worth the risk.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about flumadine

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What type of drug is rimantadine?

"Rimantadine is an antiviral drug that is only effective against influenza A virus. It will not work for colds, other types of flu, or other virus infections."

Answered by AI

What is the generic name for flumadine?

"The generic name of the medication is Rimantadine. It is taken orally."

Answered by AI

What does flumadine treat?

"Flumadine is a prescription medicine that is used to treat the symptoms of the Influenza A Virus. It may be used alone, or in combination with other medications. Flumadine belongs to a class of drugs known as Antivirals, which are designed to treat influenza."

Answered by AI

What is the mechanism of action of rimantadine?

"The drugs amantadine and rimantadine inhibit the uncoating of viral RNA in infected cells, which prevents viral replication from occurring."

Answered by AI

Clinical Trials for Flumadine

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