Femtrace

moderate Menopausal Vasomotor Symptoms, Menopause, moderate menopausal vulvovaginal atrophy + 1 more

Treatment

4 FDA approvals

0 Active Studies for Femtrace

Treatment for

moderate Menopausal Vasomotor Symptoms

What is Femtrace

Estradiol acetateThe Generic name of this drug

Treatment SummaryEstradiol acetate is a form of the naturally occurring hormone estrogen. It is often used to treat menopausal symptoms like hot flashes, vaginal dryness, mood changes, irregular menstrual cycles, chills, and sleeping problems. It does this by binding to special receptors in the body that act as a sort of switch for estrogenic effects. It is available in a vaginal ring called Femring, which is used to help absorb the drug and provide a sustained release of estrogen into the body.

Femringis the brand name

image of different drug pills on a surface

Femtrace Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Femring

Estradiol acetate

2003

Approved as Treatment by the FDA

Estradiol acetate, commonly known as Femring, is approved by the FDA for 4 uses like moderate menopausal vulvovaginal atrophy and Menopause .

moderate menopausal vulvovaginal atrophy

Menopause

severe menopausal vulvovaginal atrophy

moderate Menopausal Vasomotor Symptoms

Effectiveness

How Femtrace Affects PatientsEstrogen works in the body by activating Estrogen Receptor (ER) located in various organs and tissues, such as the breasts, uterus, ovaries, skin, prostate, bone, fat, and brain. Estradiol activates both types of ER: the Alpha (ERα) and the Beta (ERβ) receptors. It is also a strong activator of G Protein-coupled Estrogen Receptor (GPER), which helps to quickly cause changes in cells.

How Femtrace works in the bodyEstradiol, a hormone found in the female body, works by entering cells in organs like the female reproductive system, breasts, and brain. It then binds to a receptor in the cell's nucleus, which activates certain genes and causes the production of proteins. These proteins are responsible for the effects of Estradiol, such as increasing the amount of certain proteins in the blood and reducing the amount of follicle-stimulating hormone from the pituitary gland. Finally, these changes reverse some of the symptoms of menopause.

When to interrupt dosage

The prescribed dosage of Femtrace is contingent upon the diagnosed condition, such as moderate Menopausal Vasomotor Symptoms, moderate menopausal vulvovaginal atrophy and Menopause. The measure of dosage is described in the table below, in accordance with the technique of administration (e.g. Ring or Tablet - Oral).

Condition

Dosage

Administration

moderate Menopausal Vasomotor Symptoms

, 0.005 mg/hour, 0.01 mg/hour, 0.01 mg/[USP'U], 1.8 mg, 0.45 mg, 0.9 mg

Ring, Ring - Vaginal, , Vaginal, Oral, Tablet, Tablet - Oral

Menopause

, 0.005 mg/hour, 0.01 mg/hour, 0.01 mg/[USP'U], 1.8 mg, 0.45 mg, 0.9 mg

Ring, Ring - Vaginal, , Vaginal, Oral, Tablet, Tablet - Oral

moderate menopausal vulvovaginal atrophy

, 0.005 mg/hour, 0.01 mg/hour, 0.01 mg/[USP'U], 1.8 mg, 0.45 mg, 0.9 mg

Ring, Ring - Vaginal, , Vaginal, Oral, Tablet, Tablet - Oral

severe menopausal vulvovaginal atrophy

, 0.005 mg/hour, 0.01 mg/hour, 0.01 mg/[USP'U], 1.8 mg, 0.45 mg, 0.9 mg

Ring, Ring - Vaginal, , Vaginal, Oral, Tablet, Tablet - Oral

Warnings

There are 20 known major drug interactions with Femtrace.

Common Femtrace Drug Interactions

Drug Name

Risk Level

Description

Abemaciclib

Major

The metabolism of Abemaciclib can be increased when combined with Estradiol acetate.

Acalabrutinib

Major

The metabolism of Acalabrutinib can be increased when combined with Estradiol acetate.

Alectinib

Major

The metabolism of Alectinib can be increased when combined with Estradiol acetate.

Aminophylline

Major

The metabolism of Aminophylline can be increased when combined with Estradiol acetate.

Anagrelide

Major

The metabolism of Anagrelide can be decreased when combined with Estradiol acetate.

Femtrace Toxicity & Overdose RiskOverdosing on this drug can cause nausea and vomiting. Females may experience irregular bleeding.

image of a doctor in a lab doing drug, clinical research

Femtrace Novel Uses: Which Conditions Have a Clinical Trial Featuring Femtrace?

Currently, there are 0 active clinical trials assessing the potential of Femtrace to mitigate moderate and severe Menopausal Vulvovaginal Atrophy and other Menopause-related issues.

Condition

Clinical Trials

Trial Phases

moderate menopausal vulvovaginal atrophy

0 Actively Recruiting

moderate Menopausal Vasomotor Symptoms

0 Actively Recruiting

severe menopausal vulvovaginal atrophy

0 Actively Recruiting

Menopause

0 Actively Recruiting

Femtrace Reviews: What are patients saying about Femtrace?

5Patient Review

2/9/2009

Femtrace for "Change of Life" Signs

After trying unsuccessfully to manage my menopause symptoms with natural supplements for over a year and a half, my doctor prescribed Femtrace. This medication has been an absolute godsend--I haven't had a hot flash in years and I sleep like a baby now.

5Patient Review

4/24/2012

Femtrace for "Change of Life" Signs

I've been on hrt for 12 years and have tried, pempro and femtrace. I love femtrace but they're not making the dosage I need anymore. It did not cause bloating, stomach cramps or other abdominal symptoms.

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about femtrace

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the side effects of taking estrogen?

"The following are symptoms of premenstrual syndrome: bloating, breast tenderness or swelling, swelling in other parts of the body, feeling sick, leg cramps, headaches, indigestion, vaginal bleeding."

Answered by AI

What is Femtrace used for?

"This drug is a female hormone that helps to alleviate symptoms of menopause, like hot flashes and vaginal dryness, by replacing the estrogen the body is no longer producing."

Answered by AI

What is cenestin made of?

"Cenestin, a synthetic hormone made from soy and yam plants, will be available by prescription within 90 days in two strengths -- 0.625 mg and 0.9 mg."

Answered by AI

What type of drug is estradiol?

"Estradiol is a type of estrogen, which is a hormone that plays an important role in the female body. This medicine is taken to treat menopause symptoms, such as hot flashes and vaginal dryness. It is also used to prevent bone loss in menopausal women."

Answered by AI