Femtrace
moderate Menopausal Vasomotor Symptoms, Menopause, moderate menopausal vulvovaginal atrophy + 1 more
Treatment
4 FDA approvals
0 Active Studies for Femtrace
Treatment for
moderate Menopausal Vasomotor Symptoms
What is Femtrace
Estradiol acetate
The Generic name of this drug
Treatment Summary
Estradiol acetate is a form of the naturally occurring hormone estrogen. It is often used to treat menopausal symptoms like hot flashes, vaginal dryness, mood changes, irregular menstrual cycles, chills, and sleeping problems. It does this by binding to special receptors in the body that act as a sort of switch for estrogenic effects. It is available in a vaginal ring called Femring, which is used to help absorb the drug and provide a sustained release of estrogen into the body.
Femring
is the brand name
Femtrace Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Femring
Estradiol acetate
2003
10
Approved as Treatment by the FDA
Estradiol acetate, commonly known as Femring, is approved by the FDA for 4 uses like moderate menopausal vulvovaginal atrophy and Menopause .
moderate menopausal vulvovaginal atrophy
Menopause
severe menopausal vulvovaginal atrophy
moderate Menopausal Vasomotor Symptoms
Effectiveness
How Femtrace Affects Patients
Estrogen works in the body by activating Estrogen Receptor (ER) located in various organs and tissues, such as the breasts, uterus, ovaries, skin, prostate, bone, fat, and brain. Estradiol activates both types of ER: the Alpha (ERα) and the Beta (ERβ) receptors. It is also a strong activator of G Protein-coupled Estrogen Receptor (GPER), which helps to quickly cause changes in cells.
How Femtrace works in the body
Estradiol, a hormone found in the female body, works by entering cells in organs like the female reproductive system, breasts, and brain. It then binds to a receptor in the cell's nucleus, which activates certain genes and causes the production of proteins. These proteins are responsible for the effects of Estradiol, such as increasing the amount of certain proteins in the blood and reducing the amount of follicle-stimulating hormone from the pituitary gland. Finally, these changes reverse some of the symptoms of menopause.
When to interrupt dosage
The prescribed dosage of Femtrace is contingent upon the diagnosed condition, such as moderate Menopausal Vasomotor Symptoms, moderate menopausal vulvovaginal atrophy and Menopause. The measure of dosage is described in the table below, in accordance with the technique of administration (e.g. Ring or Tablet - Oral).
Condition
Dosage
Administration
moderate Menopausal Vasomotor Symptoms
, 0.005 mg/hour, 0.01 mg/hour, 0.01 mg/[USP'U], 1.8 mg, 0.45 mg, 0.9 mg
Ring, Ring - Vaginal, , Vaginal, Oral, Tablet, Tablet - Oral
Menopause
, 0.005 mg/hour, 0.01 mg/hour, 0.01 mg/[USP'U], 1.8 mg, 0.45 mg, 0.9 mg
Ring, Ring - Vaginal, , Vaginal, Oral, Tablet, Tablet - Oral
moderate menopausal vulvovaginal atrophy
, 0.005 mg/hour, 0.01 mg/hour, 0.01 mg/[USP'U], 1.8 mg, 0.45 mg, 0.9 mg
Ring, Ring - Vaginal, , Vaginal, Oral, Tablet, Tablet - Oral
severe menopausal vulvovaginal atrophy
, 0.005 mg/hour, 0.01 mg/hour, 0.01 mg/[USP'U], 1.8 mg, 0.45 mg, 0.9 mg
Ring, Ring - Vaginal, , Vaginal, Oral, Tablet, Tablet - Oral
Warnings
There are 20 known major drug interactions with Femtrace.
Common Femtrace Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The metabolism of Abemaciclib can be increased when combined with Estradiol acetate.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be increased when combined with Estradiol acetate.
Alectinib
Major
The metabolism of Alectinib can be increased when combined with Estradiol acetate.
Aminophylline
Major
The metabolism of Aminophylline can be increased when combined with Estradiol acetate.
Anagrelide
Major
The metabolism of Anagrelide can be decreased when combined with Estradiol acetate.
Femtrace Toxicity & Overdose Risk
Overdosing on this drug can cause nausea and vomiting. Females may experience irregular bleeding.
Femtrace Novel Uses: Which Conditions Have a Clinical Trial Featuring Femtrace?
Currently, there are 0 active clinical trials assessing the potential of Femtrace to mitigate moderate and severe Menopausal Vulvovaginal Atrophy and other Menopause-related issues.
Condition
Clinical Trials
Trial Phases
moderate menopausal vulvovaginal atrophy
0 Actively Recruiting
moderate Menopausal Vasomotor Symptoms
0 Actively Recruiting
severe menopausal vulvovaginal atrophy
0 Actively Recruiting
Menopause
0 Actively Recruiting
Femtrace Reviews: What are patients saying about Femtrace?
5
Patient Review
2/9/2009
Femtrace for "Change of Life" Signs
5
Patient Review
4/24/2012
Femtrace for "Change of Life" Signs
Patient Q&A Section about femtrace
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
What are the side effects of taking estrogen?
"The following are symptoms of premenstrual syndrome: bloating, breast tenderness or swelling, swelling in other parts of the body, feeling sick, leg cramps, headaches, indigestion, vaginal bleeding."
Answered by AI
What is Femtrace used for?
"This drug is a female hormone that helps to alleviate symptoms of menopause, like hot flashes and vaginal dryness, by replacing the estrogen the body is no longer producing."
Answered by AI
What is cenestin made of?
"Cenestin, a synthetic hormone made from soy and yam plants, will be available by prescription within 90 days in two strengths -- 0.625 mg and 0.9 mg."
Answered by AI
What type of drug is estradiol?
"Estradiol is a type of estrogen, which is a hormone that plays an important role in the female body. This medicine is taken to treat menopause symptoms, such as hot flashes and vaginal dryness. It is also used to prevent bone loss in menopausal women."
Answered by AI