Exelon

Parkinson Disease, Parkinson Disease, Dementia + 2 more
Treatment
8 FDA approvals
14 Active Studies for Exelon

What is Exelon

RivastigmineThe Generic name of this drug
Treatment SummaryRivastigmine is a medication used to treat mild to moderate Alzheimer's dementia. It belongs to a class of drugs called cholinesterase inhibitors, which work by increasing the amount of the neurotransmitter acetylcholine in the brain. Rivastigmine works by blocking the enzymes that break down acetylcholine, allowing it to remain active for longer periods of time.
Rivastigmine Tartrateis the brand name
image of different drug pills on a surface
Exelon Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Rivastigmine Tartrate
Rivastigmine
2000
128

Approved as Treatment by the FDA

Rivastigmine, also known as Rivastigmine Tartrate, is approved by the FDA for 8 uses including moderate Alzheimer's Type Dementia and moderate Dementia due to Parkinson's disease .
moderate Alzheimer's Type Dementia
Helps manage moderate Alzheimer's Type Dementia
moderate Dementia due to Parkinson's disease
Helps manage moderate Dementia due to Parkinson's disease
mild Dementia due to Parkinson's disease
Helps manage mild Dementia due to Parkinson's disease
mild Dementia of the Alzheimer's Type
Helps manage mild Dementia of the Alzheimer's Type
Alzheimer Disease
Helps manage mild Dementia of the Alzheimer's Type
Alzheimer's Disease
Helps manage moderate Alzheimer's Type Dementia
Parkinson Disease
Helps manage moderate Dementia due to Parkinson's disease
Parkinson Disease
Helps manage mild Dementia due to Parkinson's disease

Effectiveness

How Exelon Affects PatientsRivastigmine is used to treat Alzheimer's disease. It works by increasing the amount of a chemical in the brain called acetylcholine, which helps improve memory and thinking. The exact way it does this is unknown, but it is thought to work by blocking the breakdown of acetylcholine. Over time, as Alzheimer's disease gets worse, there may be fewer healthy neurons in the brain, which could mean that rivastigmine's effects may decrease.
How Exelon works in the bodyRivastigmine works by restoring the balance of a chemical in the brain called acetylcholine. It does this by blocking an enzyme that breaks down acetylcholine, leading to an increase in acetylcholine in the brain. Acetylcholine helps with memory, thinking and behavior, so increasing its levels can help with the symptoms of Alzheimer's disease. Rivastigmine is specifically targeted at acetylcholine in the brain, rather than in other parts of the body.

When to interrupt dosage

The proposed dosage of Exelon is contingent upon the distinguished disorder, for instance, Parkinson Disease, Parkinson Disease and Alzheimer's Disease. The measure of dosage fluctuates, in accordance with the delivery approach (e.g. Patch, extended release - Transdermal or Capsule - Oral) featured in the table beneath.
Condition
Dosage
Administration
Dementia
1.5 mg, , 3.0 mg, 4.5 mg, 6.0 mg, 0.46 mg/hour, 1.33 mg/hour, 0.95 mg/hour, 0.46 mg/[USP'U], 4.6 mg, 9.5 mg, 13.3 mg, 0.95 mg/[USP'U], 2.0 mg/mL, 9.0 mg/cm2, 1.8 mg/cm2
, Oral, Capsule, Capsule - Oral, Transdermal, Patch, extended release, Patch, extended release - Transdermal, Solution, Solution - Oral, Patch - Transdermal, Patch, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral
Parkinson Disease
1.5 mg, , 3.0 mg, 4.5 mg, 6.0 mg, 0.46 mg/hour, 1.33 mg/hour, 0.95 mg/hour, 0.46 mg/[USP'U], 4.6 mg, 9.5 mg, 13.3 mg, 0.95 mg/[USP'U], 2.0 mg/mL, 9.0 mg/cm2, 1.8 mg/cm2
, Oral, Capsule, Capsule - Oral, Transdermal, Patch, extended release, Patch, extended release - Transdermal, Solution, Solution - Oral, Patch - Transdermal, Patch, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral
Parkinson Disease
1.5 mg, , 3.0 mg, 4.5 mg, 6.0 mg, 0.46 mg/hour, 1.33 mg/hour, 0.95 mg/hour, 0.46 mg/[USP'U], 4.6 mg, 9.5 mg, 13.3 mg, 0.95 mg/[USP'U], 2.0 mg/mL, 9.0 mg/cm2, 1.8 mg/cm2
, Oral, Capsule, Capsule - Oral, Transdermal, Patch, extended release, Patch, extended release - Transdermal, Solution, Solution - Oral, Patch - Transdermal, Patch, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral
Alzheimer's Disease
1.5 mg, , 3.0 mg, 4.5 mg, 6.0 mg, 0.46 mg/hour, 1.33 mg/hour, 0.95 mg/hour, 0.46 mg/[USP'U], 4.6 mg, 9.5 mg, 13.3 mg, 0.95 mg/[USP'U], 2.0 mg/mL, 9.0 mg/cm2, 1.8 mg/cm2
, Oral, Capsule, Capsule - Oral, Transdermal, Patch, extended release, Patch, extended release - Transdermal, Solution, Solution - Oral, Patch - Transdermal, Patch, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral
Alzheimer Disease
1.5 mg, , 3.0 mg, 4.5 mg, 6.0 mg, 0.46 mg/hour, 1.33 mg/hour, 0.95 mg/hour, 0.46 mg/[USP'U], 4.6 mg, 9.5 mg, 13.3 mg, 0.95 mg/[USP'U], 2.0 mg/mL, 9.0 mg/cm2, 1.8 mg/cm2
, Oral, Capsule, Capsule - Oral, Transdermal, Patch, extended release, Patch, extended release - Transdermal, Solution, Solution - Oral, Patch - Transdermal, Patch, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral

Warnings

Exelon Contraindications
Condition
Risk Level
Notes
Anniversary Reaction
Do Not Combine
There are 20 known major drug interactions with Exelon.
Common Exelon Drug Interactions
Drug Name
Risk Level
Description
Metoclopramide
Major
The risk or severity of adverse effects can be increased when Rivastigmine is combined with Metoclopramide.
Acetylcholine
Minor
The risk or severity of adverse effects can be increased when Rivastigmine is combined with Acetylcholine.
Agmatine
Minor
The therapeutic efficacy of Agmatine can be decreased when used in combination with Rivastigmine.
Alcuronium
Minor
The therapeutic efficacy of Alcuronium can be decreased when used in combination with Rivastigmine.
Amantadine
Minor
The therapeutic efficacy of Amantadine can be decreased when used in combination with Rivastigmine.
image of a doctor in a lab doing drug, clinical research

Exelon Novel Uses: Which Conditions Have a Clinical Trial Featuring Exelon?

17 active trials are being conducted to investigate the potential of Exelon in treating Dementia, Alzheimer's Disease and mild Cognitive Impairment of the Alzheimer's Type.
Condition
Clinical Trials
Trial Phases
Parkinson Disease
0 Actively Recruiting
Alzheimer's Disease
3 Actively Recruiting
Phase 3, Phase 2
Parkinson Disease
0 Actively Recruiting
Dementia
11 Actively Recruiting
Phase 4, Not Applicable, Early Phase 1
Alzheimer Disease
0 Actively Recruiting

Exelon Reviews: What are patients saying about Exelon?

5Patient Review
12/31/2013
Exelon for Mild to Moderate Alzheimer's Type Dementia
My parents both took this patch for years with different dosages. After my father passed away, my mom tried to use up his dosages (9.5 mg), but it made her hallucinate and experience flu symptoms, so she changed back to a lower dosage. The only side effect now is the redness and sometimes itchiness of the skin after removing the patch, but using alcohol wipes have made those problems disappear.
5Patient Review
6/6/2008
Exelon for Alzheimer's Disease
My 89 year old grandmother took this medication and it improved her quality of life quite significantly. She became more energetic and interested in things when she was taking the medication, but when she ran out and stopped taking it, she quickly lost that energy and interest.
5Patient Review
12/30/2014
Exelon for Dementia associated with Parkinson's Disease
I was having some serious issues with my memory, so my doctor put me on Exelon. After a few months of gradually increasing the dosage, I (and more importantly, my family) started to notice an improvement in my concentration and memory retention. Unfortunately, this stopped after a while and we had to up the dosage again. So far so good, but I have experienced some nausea and insomnia which comes with the territory I suppose.
5Patient Review
4/13/2010
Exelon for Alzheimer's Disease
The drug was effective, but the patient experienced a lot of drooling, which was embarrassing.
5Patient Review
10/7/2008
Exelon for Diffuse Lewy Body Disease
My mother was prescribed this medication, and within two weeks we noticed a scary difference. She began to lose more memory, become more incoherent, and then she started getting weak until the point of falling on the kitchen floor. We took her off immediately.
View All Reviews
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Patient Q&A Section about exelon

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What type of company is Exelon?

"A paraphrased version of the text might read:

Exelon is a large energy company with many utility customers, a clean and low-cost power generation fleet, and a large retail customer base. The Exelon family of companies is involved in nearly every stage of the energy business, from generation and power sales to..."

Answered by AI

What companies does Exelon own?

"Exelon is a company that is made up of BGE, ComEd, PECO, Atlantic City Electric, Delmarva Power, and Pepco. Exelon Business Services Company is a unit that is shared by all of these different parts of the company. We are currently in a time period where the energy industry is changing rapidly and we have to adapt."

Answered by AI

What is going on with Exelon?

"Exelon is planning to finish the separation in the first quarter of 2022. The current CEO Chris Crane and management team will stay until the separation is done, which will be when SpinCo is publicly listed."

Answered by AI

Is Exelon a good stock to buy?

"A majority of analysts rate Exelon as a "Buy," with the company's average rating score being 2.54 out of a possible 5. This is based on 7 analysts rating the company as a "Buy," 6 rating it as a "Hold," and no analysts rating it as a "Sell.""

Answered by AI

Clinical Trials for Exelon

Have you considered Exelon clinical trials? We made a collection of clinical trials featuring Exelon, we think they might fit your search criteria.
Have you considered Exelon clinical trials? We made a collection of clinical trials featuring Exelon, we think they might fit your search criteria.
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