Emadine

Allergic Conjunctivitis (AC)

Treatment

1 FDA approval

1 Active Study for Emadine

Treatment for

Allergic Conjunctivitis (AC)

What is Emadine

EmedastineThe Generic name of this drug

Treatment SummaryEmedastine is a medication used as eye drops to reduce the symptoms of allergic conjunctivitis, such as redness, itching, and swelling.

Emadineis the brand name

Emadine Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Emadine

Emedastine

1998

Approved as Treatment by the FDA

Emedastine, also called Emadine, is approved by the FDA for 1 uses which include Allergic Conjunctivitis (AC) .

Allergic Conjunctivitis (AC)

Effectiveness

How Emadine Affects PatientsEmedastine is a drug that interferes with the H<sub>1</sub> receptor, a type of protein found in the human body.

How Emadine works in the bodyEmedastine is a drug that specifically targets the histamine H1 receptor. It prevents histamine from making blood vessels in the eye become wider and leaky, which can cause redness, swelling, and itching. It has no effect on other types of receptors, such as adrenergic, dopaminergic, and serotonin receptors.

When to interrupt dosage

The advised dosage of Emadine is contingent upon the identified condition. Dosage level also differs depending on the administration process (e.g. Liquid - Ophthalmic or Solution / drops) specified in the table underneath.

Condition

Dosage

Administration

Allergic Conjunctivitis (AC)

0.05 %, , 0.5 mg/mL

, Ophthalmic, Liquid, Liquid - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic

Warnings

There are 20 known major drug interactions with Emadine.

Common Emadine Drug Interactions

Drug Name

Risk Level

Description

Amiodarone

Major

The risk or severity of QTc prolongation can be increased when Emedastine is combined with Amiodarone.

Anagrelide

Major

The risk or severity of QTc prolongation can be increased when Emedastine is combined with Anagrelide.

Arsenic trioxide

Major

The risk or severity of QTc prolongation can be increased when Emedastine is combined with Arsenic trioxide.

Artemether

Major

The risk or severity of QTc prolongation can be increased when Emedastine is combined with Artemether.

Asenapine

Major

The risk or severity of QTc prolongation can be increased when Emedastine is combined with Asenapine.

Emadine Toxicity & Overdose RiskTaking the drug orally on a daily basis has been linked to feelings of drowsiness and general discomfort.

image of a doctor in a lab doing drug, clinical research

Emadine Novel Uses: Which Conditions Have a Clinical Trial Featuring Emadine?

3 clinical trials are currently being conducted to assess the potential of Emadine in providing relief for Allergic Conjunctivitis (AC).

Condition

Clinical Trials

Trial Phases

Allergic Conjunctivitis (AC)

1 Actively Recruiting

Phase 2

Emadine Reviews: What are patients saying about Emadine?

2.3Patient Review

11/17/2018

Emadine for Allergic Conjunctivitis

I went to an ophtalmologist for my eye redness. He prescribed me Emadine eye drop but it made no difference in my eye redness. I used Emadine for 1 month, and saw no results.

Patient Q&A Section about emadine

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Why was Emadine discontinued?

"For business reasons, the manufacturer (Novartis) decided to stop making emedastine in 2019. It's possible that the medication wasn't as popular as antihistamine eye drops that are available over-the-counter. The medication was not discontinued for safety reasons."

Answered by AI

What is Naphazoline hydrochloride?

"This medication is for temporary relief of eye redness, puffiness, itching, and watering that is common with allergies. Naphazoline is a decongestant and it works by narrowing the blood vessels in the eye."

Answered by AI

What is Emadine used for?

"Emadine is a prescription medicine used to treat the symptoms of Allergic Conjunctivitis. Emadine is a class of drugs called Antihistamines, Ophthalmic, and it is not known if it is safe and effective in children younger than 3 years of age."

Answered by AI

How do you use cromolyn eye drops?

"To administer eye drops, tilt the head back and pull the lower eyelid down to create a space. Place the drops into the space and release the eyelid. Close the eyes without blinking."

Answered by AI