Emadine
Allergic Conjunctivitis (AC)
Treatment
1 FDA approval
1 Active Study for Emadine
Treatment for
Allergic Conjunctivitis (AC)
What is Emadine
Emedastine
The Generic name of this drug
Treatment Summary
Emedastine is a medication used as eye drops to reduce the symptoms of allergic conjunctivitis, such as redness, itching, and swelling.
Emadine
is the brand name
Emadine Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Emadine
Emedastine
1998
1
Approved as Treatment by the FDA
Emedastine, also called Emadine, is approved by the FDA for 1 uses which include Allergic Conjunctivitis (AC) .
Allergic Conjunctivitis (AC)
Effectiveness
How Emadine Affects Patients
Emedastine is a drug that interferes with the H<sub>1</sub> receptor, a type of protein found in the human body.
How Emadine works in the body
Emedastine is a drug that specifically targets the histamine H1 receptor. It prevents histamine from making blood vessels in the eye become wider and leaky, which can cause redness, swelling, and itching. It has no effect on other types of receptors, such as adrenergic, dopaminergic, and serotonin receptors.
When to interrupt dosage
The advised dosage of Emadine is contingent upon the identified condition. Dosage level also differs depending on the administration process (e.g. Liquid - Ophthalmic or Solution / drops) specified in the table underneath.
Condition
Dosage
Administration
Allergic Conjunctivitis (AC)
0.05 %, , 0.5 mg/mL
Ophthalmic, Liquid, , Liquid - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic
Warnings
There are 20 known major drug interactions with Emadine.
Common Emadine Drug Interactions
Drug Name
Risk Level
Description
Amiodarone
Major
The risk or severity of QTc prolongation can be increased when Emedastine is combined with Amiodarone.
Anagrelide
Major
The risk or severity of QTc prolongation can be increased when Emedastine is combined with Anagrelide.
Arsenic trioxide
Major
The risk or severity of QTc prolongation can be increased when Emedastine is combined with Arsenic trioxide.
Artemether
Major
The risk or severity of QTc prolongation can be increased when Emedastine is combined with Artemether.
Asenapine
Major
The risk or severity of QTc prolongation can be increased when Emedastine is combined with Asenapine.
Emadine Toxicity & Overdose Risk
Taking the drug orally on a daily basis has been linked to feelings of drowsiness and general discomfort.
Emadine Novel Uses: Which Conditions Have a Clinical Trial Featuring Emadine?
3 clinical trials are currently being conducted to assess the potential of Emadine in providing relief for Allergic Conjunctivitis (AC).
Condition
Clinical Trials
Trial Phases
Allergic Conjunctivitis (AC)
1 Actively Recruiting
Phase 2
Emadine Reviews: What are patients saying about Emadine?
2.3
Patient Review
11/17/2018
Emadine for Allergic Conjunctivitis
Patient Q&A Section about emadine
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Why was Emadine discontinued?
"For business reasons, the manufacturer (Novartis) decided to stop making emedastine in 2019. It's possible that the medication wasn't as popular as antihistamine eye drops that are available over-the-counter. The medication was not discontinued for safety reasons."
Answered by AI
What is Naphazoline hydrochloride?
"This medication is for temporary relief of eye redness, puffiness, itching, and watering that is common with allergies. Naphazoline is a decongestant and it works by narrowing the blood vessels in the eye."
Answered by AI
What is Emadine used for?
"Emadine is a prescription medicine used to treat the symptoms of Allergic Conjunctivitis. Emadine is a class of drugs called Antihistamines, Ophthalmic, and it is not known if it is safe and effective in children younger than 3 years of age."
Answered by AI
How do you use cromolyn eye drops?
"To administer eye drops, tilt the head back and pull the lower eyelid down to create a space. Place the drops into the space and release the eyelid. Close the eyes without blinking."
Answered by AI