Econazole Nitrate

Tinea Pedis, Inflammation, Fungal eye infections + 17 more
Treatment
20 Active Studies for Econazole Nitrate

What is Econazole Nitrate

EconazoleThe Generic name of this drug
Treatment SummaryTerbinafine is an antifungal medication used to treat fungal infections on the skin, taken orally, or given as an injection. It can also be used to treat some types of bacterial infections.
Spectazoleis the brand name
image of different drug pills on a surface
Econazole Nitrate Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Spectazole
Econazole
1982
30

Effectiveness

How Econazole Nitrate Affects PatientsEconazole is a type of antifungal medicine similar to Diflucan, Nizoral, Sporanox, and Lotrimin. It stops fungal organisms from getting the materials they need to grow and stay alive, but it will not help with bacterial or viral infections.
How Econazole Nitrate works in the bodyEconazole interferes with the production of a type of cholesterol in fungal cells. This cholesterol is an essential part of the cell membrane, and when its production is blocked, it causes the cell to become more permeable. This leads to the leakage of the cell's contents. Econazole also affects other functions in the fungal cells, such as respiration, membrane phospholipids, yeast transformation, purine uptake, and the production of triglycerides and phospholipids.

When to interrupt dosage

The measure of Econazole Nitrate is contingent upon the diagnosed disorder, such as Cellulitis, Tinea cruris and Fungal eye infections. The dosage fluctuates as per the mode of delivery (e.g. Cream - Topical or Topical) featured in the table beneath.
Condition
Dosage
Administration
Tinea Pedis
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
Inflammation
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
Balanitis candida
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
Cellulitis
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
Tinea pedis of the interdigital
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
cutaneous candidiasis
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
Atopic Dermatitis
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
cutaneous dermatophyte infection
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
Shingles
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
Ringworm
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
Pityriasis versicolor
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
Skin
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
Tinea cruris
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
Fungal eye infections
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
Intertrigo
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
Tinea Corporis
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
Eczema
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
Skin candida
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
severe local inflammatory reactions
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
Mycoses
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit

Warnings

There are 20 known major drug interactions with Econazole Nitrate.
Common Econazole Nitrate Drug Interactions
Drug Name
Risk Level
Description
Alfuzosin
Major
The metabolism of Alfuzosin can be decreased when combined with Econazole.
Avanafil
Major
The metabolism of Avanafil can be decreased when combined with Econazole.
Bromocriptine
Major
The serum concentration of Bromocriptine can be increased when it is combined with Econazole.
Cabergoline
Major
The serum concentration of Cabergoline can be increased when it is combined with Econazole.
Cariprazine
Major
The metabolism of Cariprazine can be decreased when combined with Econazole.
Econazole Nitrate Toxicity & Overdose RiskSo far, there have not been any reported cases of people overdosing on econazole. The lethal dose for mice, rats, guinea pigs, and dogs were found to be 462, 668, 272, and greater than 160mg/kg respectively.
image of a doctor in a lab doing drug, clinical research

Econazole Nitrate Novel Uses: Which Conditions Have a Clinical Trial Featuring Econazole Nitrate?

303 active studies are currently assessing the potential of Econazole Nitrate to provide relief for Atopic Dermatitis, Eczema and Cellulitis.
Condition
Clinical Trials
Trial Phases
Tinea pedis of the interdigital
0 Actively Recruiting
severe local inflammatory reactions
0 Actively Recruiting
Balanitis candida
0 Actively Recruiting
Skin
0 Actively Recruiting
Shingles
14 Actively Recruiting
Phase 4, Phase 2, Phase 3, Phase 1, Not Applicable
cutaneous candidiasis
0 Actively Recruiting
Tinea cruris
0 Actively Recruiting
Cellulitis
0 Actively Recruiting
Skin candida
0 Actively Recruiting
Ringworm
0 Actively Recruiting
Fungal eye infections
0 Actively Recruiting
Eczema
0 Actively Recruiting
Mycoses
0 Actively Recruiting
Pityriasis versicolor
0 Actively Recruiting
Atopic Dermatitis
3 Actively Recruiting
Phase 2, Phase 3
Inflammation
172 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Early Phase 1, Phase 3, Phase 4
cutaneous dermatophyte infection
0 Actively Recruiting
Tinea Pedis
0 Actively Recruiting
Tinea Corporis
0 Actively Recruiting
Intertrigo
0 Actively Recruiting

Patient Q&A Section about econazole nitrate

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the side effects of econazole nitrate cream?

"Possible side effects of the medication include burning, stinging, swelling, irritation, redness, pimple-like bumps, tenderness, or flaking of the treated skin."

Answered by AI

What is econazole nitrate used for?

"Econazole topical is used to treat infections caused by a fungus or yeast. It works by killing the fungus or yeast or preventing its growth."

Answered by AI

How long does it take for econazole nitrate to work?

"How long does it take for econazole cream to work? Most people notice an improvement in symptoms after one or two weeks of using the cream. It is important to use the cream for the recommended amount of time, even if the symptoms have mostly gone away."

Answered by AI

Is econazole Nitrate an antifungal?

"This antifungal drug is very effective, as shown in dermatological studies. In these studies, about 90% of patients were cured, often after a short treatment period of 2 to 6 weeks. This is similar to what is seen with other imidazole antifungal agents."

Answered by AI

Clinical Trials for Econazole Nitrate

Have you considered Econazole Nitrate clinical trials? We made a collection of clinical trials featuring Econazole Nitrate, we think they might fit your search criteria.
Have you considered Econazole Nitrate clinical trials? We made a collection of clinical trials featuring Econazole Nitrate, we think they might fit your search criteria.
Have you considered Econazole Nitrate clinical trials? We made a collection of clinical trials featuring Econazole Nitrate, we think they might fit your search criteria.