Dronabinol

Acquired Immunodeficiency Syndrome, Obesity, Pharmacotherapy + 2 more
Treatment
20 Active Studies for Dronabinol

What is Dronabinol

DronabinolThe Generic name of this drug
Treatment SummaryDronabinol (brand name Marinol) is a synthetic form of delta-9-tetrahydrocannabinol (THC), the main active ingredient found in cannabis (marijuana). It interacts with receptors in the body that regulate appetite, pain, and other mental and physical functions. It is used to stimulate appetite and reduce nausea in people with AIDS and cancer who have not responded to traditional treatments. THC and cannabidiol (CBD) are two cannabinoids found in marijuana that have medicinal properties due to their interaction with receptors in the body. THC and CBD must be activated in order to be effective, either by
Dronabinolis the brand name
Dronabinol Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Dronabinol
Dronabinol
1994
62

Effectiveness

How Dronabinol Affects PatientsDronabinol can cause an increase in heart rate and redness in the eyes. It can also lead to changes in blood pressure, feeling faint when standing, and changes in mood, thinking, memory, and perception. These effects typically start after half an hour to an hour, peak in two to four hours, and last up to six hours. With long term use, people may become tolerant to some of the effects on the heart and brain, but not to the appetite stimulant effect which can last for up to five months.
How Dronabinol works in the bodyDronabinol is a synthetic version of the chemical found in cannabis (marijuana) known as delta-9-tetrahydrocannabinol (Δ⁹-THC). When this chemical binds to receptors in the body, it can produce effects like increased appetite, pain relief, and changes in thinking.

When to interrupt dosage

The proposed dosage of Dronabinol is contingent upon the identified illness, for example Unintentional Weight Loss, Pharmacotherapy and Acquired Immunodeficiency Syndrome. The dose fluctuates as per the delivery system (e.g. Buccal or Capsule - Oral) presented in the table below.
Condition
Dosage
Administration
Pharmacotherapy
, 2.5 mg, 10.0 mg, 5.0 mg, 5.0 mg/mL, 2.7 mg/pump actuation
, Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Capsule, Capsule - Oral, Spray - Buccal, Buccal, Spray, Solution, Solution - Oral
Anorexia
, 2.5 mg, 10.0 mg, 5.0 mg, 5.0 mg/mL, 2.7 mg/pump actuation
, Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Capsule, Capsule - Oral, Spray - Buccal, Buccal, Spray, Solution, Solution - Oral
Acquired Immunodeficiency Syndrome
, 2.5 mg, 10.0 mg, 5.0 mg, 5.0 mg/mL, 2.7 mg/pump actuation
, Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Capsule, Capsule - Oral, Spray - Buccal, Buccal, Spray, Solution, Solution - Oral
Obesity
, 2.5 mg, 10.0 mg, 5.0 mg, 5.0 mg/mL, 2.7 mg/pump actuation
, Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Capsule, Capsule - Oral, Spray - Buccal, Buccal, Spray, Solution, Solution - Oral
Disease
, 2.5 mg, 10.0 mg, 5.0 mg, 5.0 mg/mL, 2.7 mg/pump actuation
, Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Capsule, Capsule - Oral, Spray - Buccal, Buccal, Spray, Solution, Solution - Oral

Warnings

Dronabinol has four contraindications, so it should not be taken while encountering any of the conditions given in the following table.Dronabinol Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
There are 20 known major drug interactions with Dronabinol.
Common Dronabinol Drug Interactions
Drug Name
Risk Level
Description
Acenocoumarol
Major
The metabolism of Acenocoumarol can be decreased when combined with Dronabinol.
Aminophylline
Major
The metabolism of Aminophylline can be decreased when combined with Dronabinol.
Anagrelide
Major
The metabolism of Anagrelide can be decreased when combined with Dronabinol.
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Dronabinol.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Dronabinol.
Dronabinol Toxicity & Overdose RiskSYNDROS is a synthetic cannabinoid containing alcohol and should not be used by pregnant women as it can cause harm to the fetus. Breastfeeding mothers should also not take SYNDROS, as it can be transferred to the baby through breast milk and cause adverse reactions. SYNDROS has not been tested in pediatric patients, so its safety and effectiveness in this population is unknown. Elderly patients may be more sensitive to the psychological and physical effects of SYNDROS and should use caution. Overdosing on SYNDROS can lead to drowsiness, euphoria, heightened sensory awareness, altered time perception, dry
image of a doctor in a lab doing drug, clinical research

Dronabinol Novel Uses: Which Conditions Have a Clinical Trial Featuring Dronabinol?

137 active trials are being conducted to investigate the potential of Dronabinol to provide Pharmacotherapy, ameliorate Unintentional Weight Loss and enhance response to conventional therapy.
Condition
Clinical Trials
Trial Phases
Disease
0 Actively Recruiting
Acquired Immunodeficiency Syndrome
3 Actively Recruiting
Phase 1, Phase 2, Not Applicable
Pharmacotherapy
2 Actively Recruiting
Phase 4, Not Applicable
Anorexia
1 Actively Recruiting
Phase 1
Obesity
56 Actively Recruiting
Phase 2, Not Applicable, Phase 4, Phase 3

Dronabinol Reviews: What are patients saying about Dronabinol?

5Patient Review
12/8/2015
Dronabinol for Nausea and Vomiting caused by Cancer Drugs
I had stage 4 breast cancer for 5 years and never found any relief... until now. This drug completely removed my pain within just one hour, and I've been pain-free for the past three days.
4.7Patient Review
12/12/2019
Dronabinol for Nausea and Vomiting caused by Cancer Drugs
I've been using this medication to combat nausea and it works very well.
4.3Patient Review
4/6/2013
Dronabinol for Loss of Appetite with HIV
I've been eating more since starting this treatment, which is great.
4.3Patient Review
2/13/2009
Dronabinol for Nausea and Vomiting caused by Cancer Drugs
4.3Patient Review
8/11/2009
Dronabinol for Increased Hunger
View All Reviews

Patient Q&A Section about dronabinol

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does dronabinol make you feel high?

"Some people taking Marinol report feeling high."

Answered by AI

Is dronabinol a painkiller?

"Dronabinol, which contains THC,..."

Answered by AI

Is dronabinol a CBD?

"Dronabinol only includes tetrahydrocannabinol (THC) isomers and no cannabidiol."

Answered by AI

What is dronabinol used for?

"Dronabinol is a medication used to prevent or treat nausea and vomiting that may occur after cancer treatment, or to increase appetite in patients with AIDS. It is only prescribed when other medications for these conditions have been ineffective."

Answered by AI

Clinical Trials for Dronabinol

Have you considered Dronabinol clinical trials? We made a collection of clinical trials featuring Dronabinol, we think they might fit your search criteria.
Have you considered Dronabinol clinical trials? We made a collection of clinical trials featuring Dronabinol, we think they might fit your search criteria.
Have you considered Dronabinol clinical trials? We made a collection of clinical trials featuring Dronabinol, we think they might fit your search criteria.
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