Diatrizoate Meglumine

Retrograde cystourethrography, Arteriography, discography + 10 more

Treatment

12 FDA approvals

1 Active Study for Diatrizoate Meglumine

What is Diatrizoate Meglumine

Diatrizoate

The Generic name of this drug

Treatment Summary

Diatrizoate is a type of x-ray dye used to create a clearer image during diagnostic imaging tests. It can be used to study the gastrointestinal system, perform angiography, and diagnose urinary problems.

Renografin-60

is the brand name

image of different drug pills on a surface

Diatrizoate Meglumine Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Renografin-60

Diatrizoate

1956

23

Approved as Treatment by the FDA

Diatrizoate, also known as Renografin-60, is approved by the FDA for 12 uses which include computerized tomography and peripheral arteriography .

computerized tomography

peripheral arteriography

angiogram

splenoportography

Gastrointestinal and abdominal imaging procedures

Retrograde cystourethrography

Arteriography

excretory urography

Cholangiography

Arteriography

discography

selective coronary arteriography

Effectiveness

How Diatrizoate Meglumine Affects Patients

Diatrizoate is a medicine used to help doctors diagnose medical problems. It contains iodine, which blocks the x-ray radiation. Depending on how it is given, it will build up in certain areas of the body, allowing the x-ray to produce a picture of the area. The areas with the medicine will appear white on the x-ray, which will help the doctor see any conditions that may exist.

How Diatrizoate Meglumine works in the body

Diatrizoate is an X-ray contrast agent that contains iodine. It is used to create a clearer image when taking X-rays. It works because iodine is very dense and can stop X-rays. The more iodine in the solution, the better the X-ray image will be. Diatrizoate is a clear, colorless water solution, and it is safe for the body. It can be used almost anywhere in the body, including intravenously, in the spine, and in any body cavity.

When to interrupt dosage

The proposed dose of Diatrizoate Meglumine is reliant upon the identified condition, including Arteriography, angiogram and Gastrointestinal and abdominal imaging processes. The measure of dosage can be found in the following table, contingent upon the procedure of administration.

Condition

Dosage

Administration

selective coronary arteriography

, 300.0 mg/mL, 180.0 mg/mL, 527.0 mg/mL, 50.0 %, 100.0 %, 30.0 %, 60.0 %, 18.0 %, 52.7 %, 66.0 %, 52.0 %, 660.0 mg/mL, 600.0 mg/mL, 760.0 mg/mL, 700.0 mg/mL, 76.0 %, 520.0 mg/mL, 0.6 mg/mg, 500.0 mg/mL, 0.9974 mg/mg

, Intravenous, Injection, solution, Injection, solution - Intravenous, Oral; Rectal, Intravesical, Injection, solution - Intravesical, Liquid, Injection, solution - Intrauterine, Intrauterine, Oral, Solution, Solution - Oral, Liquid - Intravenous, Powder, Powder - Oral, Liquid - Oral, Liquid - Oral; Rectal, Powder - Oral; Rectal, Intra-arterial; Intravenous, Liquid - Intra-arterial; Intravenous, Liquid - Intramuscular; Intravenous, Intramuscular; Intravenous, Solution - Intravenous, Solution - Intra-arterial; Intravenous, Liquid - Intrauterine, Solution - Oral; Rectal, Powder, for solution - Oral, Intravascular, Injection, solution - Intravascular, Powder, for solution

Arteriography

, 300.0 mg/mL, 180.0 mg/mL, 527.0 mg/mL, 50.0 %, 100.0 %, 30.0 %, 60.0 %, 18.0 %, 52.7 %, 66.0 %, 52.0 %, 660.0 mg/mL, 600.0 mg/mL, 760.0 mg/mL, 700.0 mg/mL, 76.0 %, 520.0 mg/mL, 0.6 mg/mg, 500.0 mg/mL, 0.9974 mg/mg

, Intravenous, Injection, solution, Injection, solution - Intravenous, Oral; Rectal, Intravesical, Injection, solution - Intravesical, Liquid, Injection, solution - Intrauterine, Intrauterine, Oral, Solution, Solution - Oral, Liquid - Intravenous, Powder, Powder - Oral, Liquid - Oral, Liquid - Oral; Rectal, Powder - Oral; Rectal, Intra-arterial; Intravenous, Liquid - Intra-arterial; Intravenous, Liquid - Intramuscular; Intravenous, Intramuscular; Intravenous, Solution - Intravenous, Solution - Intra-arterial; Intravenous, Liquid - Intrauterine, Solution - Oral; Rectal, Powder, for solution - Oral, Intravascular, Injection, solution - Intravascular, Powder, for solution

hysterosalpingogram

, 300.0 mg/mL, 180.0 mg/mL, 527.0 mg/mL, 50.0 %, 100.0 %, 30.0 %, 60.0 %, 18.0 %, 52.7 %, 66.0 %, 52.0 %, 660.0 mg/mL, 600.0 mg/mL, 760.0 mg/mL, 700.0 mg/mL, 76.0 %, 520.0 mg/mL, 0.6 mg/mg, 500.0 mg/mL, 0.9974 mg/mg

, Intravenous, Injection, solution, Injection, solution - Intravenous, Oral; Rectal, Intravesical, Injection, solution - Intravesical, Liquid, Injection, solution - Intrauterine, Intrauterine, Oral, Solution, Solution - Oral, Liquid - Intravenous, Powder, Powder - Oral, Liquid - Oral, Liquid - Oral; Rectal, Powder - Oral; Rectal, Intra-arterial; Intravenous, Liquid - Intra-arterial; Intravenous, Liquid - Intramuscular; Intravenous, Intramuscular; Intravenous, Solution - Intravenous, Solution - Intra-arterial; Intravenous, Liquid - Intrauterine, Solution - Oral; Rectal, Powder, for solution - Oral, Intravascular, Injection, solution - Intravascular, Powder, for solution

excretory urography

, 300.0 mg/mL, 180.0 mg/mL, 527.0 mg/mL, 50.0 %, 100.0 %, 30.0 %, 60.0 %, 18.0 %, 52.7 %, 66.0 %, 52.0 %, 660.0 mg/mL, 600.0 mg/mL, 760.0 mg/mL, 700.0 mg/mL, 76.0 %, 520.0 mg/mL, 0.6 mg/mg, 500.0 mg/mL, 0.9974 mg/mg

, Intravenous, Injection, solution, Injection, solution - Intravenous, Oral; Rectal, Intravesical, Injection, solution - Intravesical, Liquid, Injection, solution - Intrauterine, Intrauterine, Oral, Solution, Solution - Oral, Liquid - Intravenous, Powder, Powder - Oral, Liquid - Oral, Liquid - Oral; Rectal, Powder - Oral; Rectal, Intra-arterial; Intravenous, Liquid - Intra-arterial; Intravenous, Liquid - Intramuscular; Intravenous, Intramuscular; Intravenous, Solution - Intravenous, Solution - Intra-arterial; Intravenous, Liquid - Intrauterine, Solution - Oral; Rectal, Powder, for solution - Oral, Intravascular, Injection, solution - Intravascular, Powder, for solution

splenoportography

, 300.0 mg/mL, 180.0 mg/mL, 527.0 mg/mL, 50.0 %, 100.0 %, 30.0 %, 60.0 %, 18.0 %, 52.7 %, 66.0 %, 52.0 %, 660.0 mg/mL, 600.0 mg/mL, 760.0 mg/mL, 700.0 mg/mL, 76.0 %, 520.0 mg/mL, 0.6 mg/mg, 500.0 mg/mL, 0.9974 mg/mg

, Intravenous, Injection, solution, Injection, solution - Intravenous, Oral; Rectal, Intravesical, Injection, solution - Intravesical, Liquid, Injection, solution - Intrauterine, Intrauterine, Oral, Solution, Solution - Oral, Liquid - Intravenous, Powder, Powder - Oral, Liquid - Oral, Liquid - Oral; Rectal, Powder - Oral; Rectal, Intra-arterial; Intravenous, Liquid - Intra-arterial; Intravenous, Liquid - Intramuscular; Intravenous, Intramuscular; Intravenous, Solution - Intravenous, Solution - Intra-arterial; Intravenous, Liquid - Intrauterine, Solution - Oral; Rectal, Powder, for solution - Oral, Intravascular, Injection, solution - Intravascular, Powder, for solution

peripheral arteriography

, 300.0 mg/mL, 180.0 mg/mL, 527.0 mg/mL, 50.0 %, 100.0 %, 30.0 %, 60.0 %, 18.0 %, 52.7 %, 66.0 %, 52.0 %, 660.0 mg/mL, 600.0 mg/mL, 760.0 mg/mL, 700.0 mg/mL, 76.0 %, 520.0 mg/mL, 0.6 mg/mg, 500.0 mg/mL, 0.9974 mg/mg

, Intravenous, Injection, solution, Injection, solution - Intravenous, Oral; Rectal, Intravesical, Injection, solution - Intravesical, Liquid, Injection, solution - Intrauterine, Intrauterine, Oral, Solution, Solution - Oral, Liquid - Intravenous, Powder, Powder - Oral, Liquid - Oral, Liquid - Oral; Rectal, Powder - Oral; Rectal, Intra-arterial; Intravenous, Liquid - Intra-arterial; Intravenous, Liquid - Intramuscular; Intravenous, Intramuscular; Intravenous, Solution - Intravenous, Solution - Intra-arterial; Intravenous, Liquid - Intrauterine, Solution - Oral; Rectal, Powder, for solution - Oral, Intravascular, Injection, solution - Intravascular, Powder, for solution

Cholangiography

, 300.0 mg/mL, 180.0 mg/mL, 527.0 mg/mL, 50.0 %, 100.0 %, 30.0 %, 60.0 %, 18.0 %, 52.7 %, 66.0 %, 52.0 %, 660.0 mg/mL, 600.0 mg/mL, 760.0 mg/mL, 700.0 mg/mL, 76.0 %, 520.0 mg/mL, 0.6 mg/mg, 500.0 mg/mL, 0.9974 mg/mg

, Intravenous, Injection, solution, Injection, solution - Intravenous, Oral; Rectal, Intravesical, Injection, solution - Intravesical, Liquid, Injection, solution - Intrauterine, Intrauterine, Oral, Solution, Solution - Oral, Liquid - Intravenous, Powder, Powder - Oral, Liquid - Oral, Liquid - Oral; Rectal, Powder - Oral; Rectal, Intra-arterial; Intravenous, Liquid - Intra-arterial; Intravenous, Liquid - Intramuscular; Intravenous, Intramuscular; Intravenous, Solution - Intravenous, Solution - Intra-arterial; Intravenous, Liquid - Intrauterine, Solution - Oral; Rectal, Powder, for solution - Oral, Intravascular, Injection, solution - Intravascular, Powder, for solution

Retrograde cystourethrography

, 300.0 mg/mL, 180.0 mg/mL, 527.0 mg/mL, 50.0 %, 100.0 %, 30.0 %, 60.0 %, 18.0 %, 52.7 %, 66.0 %, 52.0 %, 660.0 mg/mL, 600.0 mg/mL, 760.0 mg/mL, 700.0 mg/mL, 76.0 %, 520.0 mg/mL, 0.6 mg/mg, 500.0 mg/mL, 0.9974 mg/mg

, Intravenous, Injection, solution, Injection, solution - Intravenous, Oral; Rectal, Intravesical, Injection, solution - Intravesical, Liquid, Injection, solution - Intrauterine, Intrauterine, Oral, Solution, Solution - Oral, Liquid - Intravenous, Powder, Powder - Oral, Liquid - Oral, Liquid - Oral; Rectal, Powder - Oral; Rectal, Intra-arterial; Intravenous, Liquid - Intra-arterial; Intravenous, Liquid - Intramuscular; Intravenous, Intramuscular; Intravenous, Solution - Intravenous, Solution - Intra-arterial; Intravenous, Liquid - Intrauterine, Solution - Oral; Rectal, Powder, for solution - Oral, Intravascular, Injection, solution - Intravascular, Powder, for solution

Arteriography

, 300.0 mg/mL, 180.0 mg/mL, 527.0 mg/mL, 50.0 %, 100.0 %, 30.0 %, 60.0 %, 18.0 %, 52.7 %, 66.0 %, 52.0 %, 660.0 mg/mL, 600.0 mg/mL, 760.0 mg/mL, 700.0 mg/mL, 76.0 %, 520.0 mg/mL, 0.6 mg/mg, 500.0 mg/mL, 0.9974 mg/mg

, Intravenous, Injection, solution, Injection, solution - Intravenous, Oral; Rectal, Intravesical, Injection, solution - Intravesical, Liquid, Injection, solution - Intrauterine, Intrauterine, Oral, Solution, Solution - Oral, Liquid - Intravenous, Powder, Powder - Oral, Liquid - Oral, Liquid - Oral; Rectal, Powder - Oral; Rectal, Intra-arterial; Intravenous, Liquid - Intra-arterial; Intravenous, Liquid - Intramuscular; Intravenous, Intramuscular; Intravenous, Solution - Intravenous, Solution - Intra-arterial; Intravenous, Liquid - Intrauterine, Solution - Oral; Rectal, Powder, for solution - Oral, Intravascular, Injection, solution - Intravascular, Powder, for solution

discography

, 300.0 mg/mL, 180.0 mg/mL, 527.0 mg/mL, 50.0 %, 100.0 %, 30.0 %, 60.0 %, 18.0 %, 52.7 %, 66.0 %, 52.0 %, 660.0 mg/mL, 600.0 mg/mL, 760.0 mg/mL, 700.0 mg/mL, 76.0 %, 520.0 mg/mL, 0.6 mg/mg, 500.0 mg/mL, 0.9974 mg/mg

, Intravenous, Injection, solution, Injection, solution - Intravenous, Oral; Rectal, Intravesical, Injection, solution - Intravesical, Liquid, Injection, solution - Intrauterine, Intrauterine, Oral, Solution, Solution - Oral, Liquid - Intravenous, Powder, Powder - Oral, Liquid - Oral, Liquid - Oral; Rectal, Powder - Oral; Rectal, Intra-arterial; Intravenous, Liquid - Intra-arterial; Intravenous, Liquid - Intramuscular; Intravenous, Intramuscular; Intravenous, Solution - Intravenous, Solution - Intra-arterial; Intravenous, Liquid - Intrauterine, Solution - Oral; Rectal, Powder, for solution - Oral, Intravascular, Injection, solution - Intravascular, Powder, for solution

angiogram

, 300.0 mg/mL, 180.0 mg/mL, 527.0 mg/mL, 50.0 %, 100.0 %, 30.0 %, 60.0 %, 18.0 %, 52.7 %, 66.0 %, 52.0 %, 660.0 mg/mL, 600.0 mg/mL, 760.0 mg/mL, 700.0 mg/mL, 76.0 %, 520.0 mg/mL, 0.6 mg/mg, 500.0 mg/mL, 0.9974 mg/mg

, Intravenous, Injection, solution, Injection, solution - Intravenous, Oral; Rectal, Intravesical, Injection, solution - Intravesical, Liquid, Injection, solution - Intrauterine, Intrauterine, Oral, Solution, Solution - Oral, Liquid - Intravenous, Powder, Powder - Oral, Liquid - Oral, Liquid - Oral; Rectal, Powder - Oral; Rectal, Intra-arterial; Intravenous, Liquid - Intra-arterial; Intravenous, Liquid - Intramuscular; Intravenous, Intramuscular; Intravenous, Solution - Intravenous, Solution - Intra-arterial; Intravenous, Liquid - Intrauterine, Solution - Oral; Rectal, Powder, for solution - Oral, Intravascular, Injection, solution - Intravascular, Powder, for solution

Gastrointestinal and abdominal imaging procedures

, 300.0 mg/mL, 180.0 mg/mL, 527.0 mg/mL, 50.0 %, 100.0 %, 30.0 %, 60.0 %, 18.0 %, 52.7 %, 66.0 %, 52.0 %, 660.0 mg/mL, 600.0 mg/mL, 760.0 mg/mL, 700.0 mg/mL, 76.0 %, 520.0 mg/mL, 0.6 mg/mg, 500.0 mg/mL, 0.9974 mg/mg

, Intravenous, Injection, solution, Injection, solution - Intravenous, Oral; Rectal, Intravesical, Injection, solution - Intravesical, Liquid, Injection, solution - Intrauterine, Intrauterine, Oral, Solution, Solution - Oral, Liquid - Intravenous, Powder, Powder - Oral, Liquid - Oral, Liquid - Oral; Rectal, Powder - Oral; Rectal, Intra-arterial; Intravenous, Liquid - Intra-arterial; Intravenous, Liquid - Intramuscular; Intravenous, Intramuscular; Intravenous, Solution - Intravenous, Solution - Intra-arterial; Intravenous, Liquid - Intrauterine, Solution - Oral; Rectal, Powder, for solution - Oral, Intravascular, Injection, solution - Intravascular, Powder, for solution

computerized tomography

, 300.0 mg/mL, 180.0 mg/mL, 527.0 mg/mL, 50.0 %, 100.0 %, 30.0 %, 60.0 %, 18.0 %, 52.7 %, 66.0 %, 52.0 %, 660.0 mg/mL, 600.0 mg/mL, 760.0 mg/mL, 700.0 mg/mL, 76.0 %, 520.0 mg/mL, 0.6 mg/mg, 500.0 mg/mL, 0.9974 mg/mg

, Intravenous, Injection, solution, Injection, solution - Intravenous, Oral; Rectal, Intravesical, Injection, solution - Intravesical, Liquid, Injection, solution - Intrauterine, Intrauterine, Oral, Solution, Solution - Oral, Liquid - Intravenous, Powder, Powder - Oral, Liquid - Oral, Liquid - Oral; Rectal, Powder - Oral; Rectal, Intra-arterial; Intravenous, Liquid - Intra-arterial; Intravenous, Liquid - Intramuscular; Intravenous, Intramuscular; Intravenous, Solution - Intravenous, Solution - Intra-arterial; Intravenous, Liquid - Intrauterine, Solution - Oral; Rectal, Powder, for solution - Oral, Intravascular, Injection, solution - Intravascular, Powder, for solution

Warnings

Diatrizoate Meglumine has eight contraindications and should not be taken while facing conditions in the table below.

Diatrizoate Meglumine Contraindications

Condition

Risk Level

Notes

Carotid Arteries

Do Not Combine

Anuria

Do Not Combine

dehydrated azotemic patients

Do Not Combine

Sphenoid Sinusitis

Do Not Combine

direct injection into spinal arteries

Do Not Combine

Myelography

Do Not Combine

Structure of vertebral artery

Do Not Combine

use for examination of dorsal cysts

Do Not Combine

There are 20 known major drug interactions with Diatrizoate Meglumine.

Common Diatrizoate Meglumine Drug Interactions

Drug Name

Risk Level

Description

Abacavir

Minor

Diatrizoate may decrease the excretion rate of Abacavir which could result in a higher serum level.

Acetaminophen

Minor

Diatrizoate may decrease the excretion rate of Acetaminophen which could result in a higher serum level.

Aclidinium

Minor

Diatrizoate may decrease the excretion rate of Aclidinium which could result in a higher serum level.

Acrivastine

Minor

Diatrizoate may decrease the excretion rate of Acrivastine which could result in a higher serum level.

Albutrepenonacog alfa

Minor

Diatrizoate may decrease the excretion rate of Albutrepenonacog alfa which could result in a higher serum level.

Diatrizoate Meglumine Toxicity & Overdose Risk

Overdosing on diatrizoate can be damaging to kidney cells, causing cell death, energy failure, calcium imbalance, and altering the shape of the cells. It is believed that these effects are caused by an increase in oxidative stress.

image of a doctor in a lab doing drug, clinical research

Diatrizoate Meglumine Novel Uses: Which Conditions Have a Clinical Trial Featuring Diatrizoate Meglumine?

Investigations are ongoing to assess the potential of Diatrizoate Meglumine for use in hysterosalpingogram, Arteriography and excretory urography.

Condition

Clinical Trials

Trial Phases

selective coronary arteriography

0 Actively Recruiting

Arteriography

0 Actively Recruiting

splenoportography

0 Actively Recruiting

Arteriography

0 Actively Recruiting

hysterosalpingogram

0 Actively Recruiting

Cholangiography

0 Actively Recruiting

computerized tomography

1 Actively Recruiting

Phase 2

Retrograde cystourethrography

0 Actively Recruiting

discography

0 Actively Recruiting

peripheral arteriography

0 Actively Recruiting

angiogram

0 Actively Recruiting

excretory urography

0 Actively Recruiting

Gastrointestinal and abdominal imaging procedures

0 Actively Recruiting

Diatrizoate Meglumine Reviews: What are patients saying about Diatrizoate Meglumine?

2

Patient Review

6/6/2014

Diatrizoate Meglumine for Process of Making X-Rays of Stomach or Intestines

This didn't work well for me.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about diatrizoate meglumine

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How do you take diatrizoate?

"Use this medication 15 to 30 minutes before your test, unless your doctor has told you to do otherwise."

Answered by AI

What is diatrizoate sodium used for?

"Diatrizoate is a contrast agent that is injected and used in radiology. It is commonly used as an x-ray contrast medium and can be used for gastrointestinal studies, angiography, and urography."

Answered by AI

What is diatrizoate meglumine used for?

"Diatrizoate meglumine injection helps to improve the clarity of imaging for diagnosing issues in the urinary bladder. Diatrizoate meglumine is a radiopaque contrast agent which means it makes different parts of the body easier to see during medical procedures such as retrograde cystourethrography."

Answered by AI

What is gastrografin used for?

"Gastrografin contains iodine and is used as a contrast medium to clearly show the area your doctor wants to investigate on X-rays, which will be your gullet (oesophagus), stomach, or intestines (gastrointestinal tract)."

Answered by AI

Clinical Trials for Diatrizoate Meglumine