Aspirin for Fallopian Tube Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial will test if taking a small amount of aspirin daily can reduce inflammation in women who are having their fallopian tubes removed.
Will I have to stop taking my current medications?
The trial requires that you are not currently taking regular aspirin, NSAIDs (non-steroidal anti-inflammatory drugs), acetaminophen, or chronic steroidal anti-inflammatory medications. If you are on these medications, you would need to stop them to participate.
Is aspirin generally safe for humans?
Aspirin (also known as acetylsalicylic acid or ASA) is widely used and generally considered safe for humans, especially for long-term use in preventing heart attacks and strokes. However, it can cause side effects like stomach upset or bleeding, so it's important to use it under medical supervision.12345
How does aspirin differ from other drugs for fallopian tube cancer?
Aspirin is unique because it is a common anti-inflammatory drug that may help improve survival in various cancers, including ovarian cancer, by inhibiting tumor growth and progression. Unlike traditional cancer treatments, aspirin is widely used for other conditions and may offer a novel approach to managing fallopian tube cancer.12367
What evidence supports the effectiveness of aspirin as a drug for fallopian tube cancer?
Who Is on the Research Team?
Laura L. Holman
Principal Investigator
Stephenson Cancer Center, University of Oklahoma Health Sciences Center
Are You a Good Fit for This Trial?
This trial is for women over 21 who are having surgery to remove their fallopian tubes and have completed childbearing. They should not be at high risk for fallopian tube cancer, nor have a history of gynecologic cancer, bleeding disorders, or regular use of NSAIDs or aspirin. Women with gastritis, peptic ulcers, aspirin allergies, asthma with nasal polyps are excluded.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive low dose aspirin for 14 days prior to surgery for removal of fallopian tubes
Surgery
Participants undergo surgery to have their fallopian tubes removed
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Aspirin
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Oklahoma
Lead Sponsor