Cleviprex

Hypertensive disease
Treatment
18 Active Studies for Cleviprex

What is Cleviprex

ClevidipineThe Generic name of this drug
Treatment SummaryClevidipine is a type of medication used to lower blood pressure in patients who cannot take oral medications. It works by blocking calcium channels in the walls of the blood vessels, reducing the force of the blood flow and lowering blood pressure.
Cleviprexis the brand name
image of different drug pills on a surface
Cleviprex Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Cleviprex
Clevidipine
2008
6

Effectiveness

How Cleviprex Affects PatientsClevidipine is a type of drug that helps to widen small arteries and veins, which can reduce blood pressure. It belongs to a class of drugs called dihydropyridine calcium channel blockers, and is the first of its kind. Studies have shown that it works by relaxing the smooth muscle cells that line small arteries, but does not reduce central venous pressure or affect the heart's output.
How Cleviprex works in the bodyClevidipine blocks the entry of calcium into muscle cells of the heart and blood vessels. This helps the heart and arteries relax, allowing more oxygen to reach the heart muscle and resulting in improved blood flow.

When to interrupt dosage

The quantity of Cleviprex is contingent upon the determined condition. The dosage is subject to the technique of delivery as noted in the table below.
Condition
Dosage
Administration
Hypertensive disease
, 0.5 mg/mL
, Intravenous, Emulsion, Emulsion - Intravenous

Warnings

There are 20 known major drug interactions with Cleviprex.
Common Cleviprex Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The metabolism of Abemaciclib can be increased when combined with Clevidipine.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be increased when combined with Clevidipine.
Alectinib
Major
The metabolism of Alectinib can be increased when combined with Clevidipine.
Alpelisib
Major
The metabolism of Alpelisib can be increased when combined with Clevidipine.
Aminophylline
Major
The metabolism of Aminophylline can be increased when combined with Clevidipine.
image of a doctor in a lab doing drug, clinical research

Cleviprex Novel Uses: Which Conditions Have a Clinical Trial Featuring Cleviprex?

Investigation is currently ongoing in 18 active studies to examine the potential of Cleviprex in relieving symptoms of Hypertensive Disease.
Condition
Clinical Trials
Trial Phases
Hypertensive disease
18 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3

Cleviprex Reviews: What are patients saying about Cleviprex?

3.3Patient Review
9/8/2011
Cleviprex for High Blood Pressure
1Patient Review
12/21/2013
Cleviprex for High Blood Pressure
Do not use this drug. It caused my blood pressure to drop too quickly and I ended up having a stroke as a result.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about cleviprex

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does CLEVIPREX affect heart rate?

"Cleviprex is not a beta blocker and will not reduce heart rate. There is no protection against the effects of abrupt beta blocker withdrawal when taking this medication. Beta blockers should be tapered off slowly to avoid withdrawal effects."

Answered by AI

Is CLEVIPREX a sedative?

"Clevidipine (Cleviprex®) is an IV antihypertensive agent indicated for the reduction of blood pressure when oral therapy is not feasible or not desired. Both products are supplied as sterile, preservative-free solutions in 50 mL single-dose vials.

Although both products are supplied in preservative-free, 50 mL, single-dose vials and have very similar names, they are different medications that should not be confused.

Both Propofol (Diprivan®) and Clevidipine (Cleviprex®) are supplied in preservative-free, 50 mL, single-dose vials. However, they are different medications that should not be confused. Propofol (Diprivan®) is an intravenous (IV) sedative agent used in the induction and maintenance of general anesthesia, monitored anesthesia care sedation, procedural sedation, and sedation for mechanical ventilation. Clevidipine (Cleviprex®) is an IV antihypertensive agent indicated for the reduction of blood pressure when oral therapy is not feasible or not desired."

Answered by AI

Does CLEVIPREX increase blood pressure?

"Cleviprex can be used to lower blood pressure when oral medication is not an option or is not desired."

Answered by AI

What is CLEVIPREX used for?

"CLEVIPREX can help to lower blood pressure in both the perioperative setting and in cases of acute severe hypertension. CLEVIPREX is a ready-to-use option and only takes ~1 minute to start working."

Answered by AI

Clinical Trials for Cleviprex

Have you considered Cleviprex clinical trials? We made a collection of clinical trials featuring Cleviprex, we think they might fit your search criteria.
Have you considered Cleviprex clinical trials? We made a collection of clinical trials featuring Cleviprex, we think they might fit your search criteria.
Have you considered Cleviprex clinical trials? We made a collection of clinical trials featuring Cleviprex, we think they might fit your search criteria.